Name : Torpedo californica acetylcholinesterase in complex with indolic multi-target directed ligand MR28926

Revelation date : 21-Nov-2018

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Santoni, G., Lalut, J., Karila, D., Lecoutey, C., Davis, A., Nachon, F., Sillman, I., Sussman, J., Weik, M., Maurice, T., Dallemagne, P., Rochais, C.

Ligand : Inhibitor Sigma1R-ACHE-6a Ligand in structure: Ligplot

References (1)

Title : Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase - Lalut_2019_Eur.J.Med.Chem_162_234
Author(s) : Lalut J , Santoni G , Karila D , Lecoutey C , Davis A , Nachon F , Silman I , Sussman JL , Weik M , Maurice T , Dallemagne P , Rochais C
Ref : Eur Journal of Medicinal Chemistry , 162 :234 , 2019
Abstract :
PubMedSearch : Lalut_2019_Eur.J.Med.Chem_162_234
PubMedID: 30447434
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 6EZH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6EZH Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6EZH Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6EZH 3D, interactive encyclopedia of proteins - PROTEOPEDIA server