6I5G

Name : X-ray structure of human soluble Epoxide yhdrolase C-terminal domain (hsEH CTD)in complex with 15d-PGJ2

Revelation date : 29-May-2019

Family : Epoxide_hydrolase

Gene_locus : human-EPHX2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Abis, G., Charles, R.L., Kopec, J., Yue, W.W., Atkinson, R.A., Bui, T.T.T., Lynham, S., Popova, S., Sun, Y.-B., Fraternali, F., Eaton, P., Conte, M.R.

Ligand : Inhibitor 15d-PGJ2 Ligand in structure: Ligplot

References (1)

Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188
Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR
Ref : Commun Biol , 2 :188 , 2019
Abstract :
PubMedSearch : Abis_2019_Commun.Biol_2_188
PubMedID: 31123712
Gene_locus related to this paper: human-EPHX2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6I5G Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6I5G Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6I5G Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6I5G 3D, interactive encyclopedia of proteins - PROTEOPEDIA server