| Title : A novel inhibitor of soluble epoxide hydrolase that adducts C521 is cardioprotective - Charles_2025_Redox.Biol_89_103974 |
| Author(s) : Charles RL , Fernandez-Caggiano M , Rudyk O , Tyson-Hirst I , Ehteramyan M , Switzer CH , Buccafusca R , Rajeeve V , Bianchi K , Morales V , Finch AJ , Eaton P |
| Ref : Redox Biol , 89 :103974 , 2025 |
| Abstract : |
| PubMedSearch : Charles_2025_Redox.Biol_89_103974 |
| PubMedID: 41406572 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension - Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| Author(s) : Simoes de Jesus D , Buffonge S , Abis G , Buccafusca R , Baliga R , Warren HR , Hobbs A , Ruppert C , Weiss A , Schermuly RT , Eaton P , Charles RL |
| Ref : American Journal of Respiratory & Critical Care Medicine , : , 2025 |
| Abstract : |
| PubMedSearch : Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| PubMedID: 40504769 |
| Title : Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension - Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| Author(s) : Simoes de Jesus D , Buffonge S , Abis G , Buccafusca R , Baliga R , Warren HR , Hobbs A , Ruppert C , Weiss A , Schermuly RT , Eaton P , Charles RL |
| Ref : American Journal of Respiratory & Critical Care Medicine , : , 2025 |
| Abstract : |
| PubMedSearch : Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| PubMedID: 40504769 |
| Title : Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension - Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| Author(s) : Simoes de Jesus D , Buffonge S , Abis G , Buccafusca R , Baliga R , Warren HR , Hobbs A , Ruppert C , Weiss A , Schermuly RT , Eaton P , Charles RL |
| Ref : American Journal of Respiratory & Critical Care Medicine , : , 2025 |
| Abstract : |
| PubMedSearch : Simoes_2025_Am.J.Respir.Crit.Care.Med__ |
| PubMedID: 40504769 |
| Title : A novel inhibitor of soluble epoxide hydrolase that adducts C521 is cardioprotective - Charles_2025_Redox.Biol_89_103974 |
| Author(s) : Charles RL , Fernandez-Caggiano M , Rudyk O , Tyson-Hirst I , Ehteramyan M , Switzer CH , Buccafusca R , Rajeeve V , Bianchi K , Morales V , Finch AJ , Eaton P |
| Ref : Redox Biol , 89 :103974 , 2025 |
| Abstract : |
| PubMedSearch : Charles_2025_Redox.Biol_89_103974 |
| PubMedID: 41406572 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : A novel inhibitor of soluble epoxide hydrolase that adducts C521 is cardioprotective - Charles_2025_Redox.Biol_89_103974 |
| Author(s) : Charles RL , Fernandez-Caggiano M , Rudyk O , Tyson-Hirst I , Ehteramyan M , Switzer CH , Buccafusca R , Rajeeve V , Bianchi K , Morales V , Finch AJ , Eaton P |
| Ref : Redox Biol , 89 :103974 , 2025 |
| Abstract : |
| PubMedSearch : Charles_2025_Redox.Biol_89_103974 |
| PubMedID: 41406572 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease - Charles_2022_Cells_11_ |
| Author(s) : Charles R , Eaton P |
| Ref : Cells , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Charles_2022_Cells_11_ |
| PubMedID: 35741062 |
| Title : Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease - Charles_2022_Cells_11_ |
| Author(s) : Charles R , Eaton P |
| Ref : Cells , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Charles_2022_Cells_11_ |
| PubMedID: 35741062 |
| Title : Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease - Charles_2022_Cells_11_ |
| Author(s) : Charles R , Eaton P |
| Ref : Cells , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Charles_2022_Cells_11_ |
| PubMedID: 35741062 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : Redox regulation of soluble epoxide hydrolase does not affect pain behavior in mice - Wack_2020_Neurosci.Lett_721_134798 |
| Author(s) : Wack G , Eaton P , Schmidtko A , Kallenborn-Gerhardt W |
| Ref : Neuroscience Letters , 721 :134798 , 2020 |
| Abstract : |
| PubMedSearch : Wack_2020_Neurosci.Lett_721_134798 |
| PubMedID: 32006628 |
| Title : Redox regulation of soluble epoxide hydrolase does not affect pain behavior in mice - Wack_2020_Neurosci.Lett_721_134798 |
| Author(s) : Wack G , Eaton P , Schmidtko A , Kallenborn-Gerhardt W |
| Ref : Neuroscience Letters , 721 :134798 , 2020 |
| Abstract : |
| PubMedSearch : Wack_2020_Neurosci.Lett_721_134798 |
| PubMedID: 32006628 |
| Title : Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth - Cho_2020_Redox.Biol_29_101405 |
| Author(s) : Cho HJ , Switzer CH , Kamynina A , Charles R , Rudyk O , Ng T , Burgoyne JR , Eaton P |
| Ref : Redox Biol , 29 :101405 , 2020 |
| Abstract : |
| PubMedSearch : Cho_2020_Redox.Biol_29_101405 |
| PubMedID: 31926628 |
| Title : Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth - Cho_2020_Redox.Biol_29_101405 |
| Author(s) : Cho HJ , Switzer CH , Kamynina A , Charles R , Rudyk O , Ng T , Burgoyne JR , Eaton P |
| Ref : Redox Biol , 29 :101405 , 2020 |
| Abstract : |
| PubMedSearch : Cho_2020_Redox.Biol_29_101405 |
| PubMedID: 31926628 |
| Title : Redox regulation of soluble epoxide hydrolase does not affect pain behavior in mice - Wack_2020_Neurosci.Lett_721_134798 |
| Author(s) : Wack G , Eaton P , Schmidtko A , Kallenborn-Gerhardt W |
| Ref : Neuroscience Letters , 721 :134798 , 2020 |
| Abstract : |
| PubMedSearch : Wack_2020_Neurosci.Lett_721_134798 |
| PubMedID: 32006628 |
| Title : Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth - Cho_2020_Redox.Biol_29_101405 |
| Author(s) : Cho HJ , Switzer CH , Kamynina A , Charles R , Rudyk O , Ng T , Burgoyne JR , Eaton P |
| Ref : Redox Biol , 29 :101405 , 2020 |
| Abstract : |
| PubMedSearch : Cho_2020_Redox.Biol_29_101405 |
| PubMedID: 31926628 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |
| Title : Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase - Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| Author(s) : Charles RL , Rudyk O , Prysyazhna O , Kamynina A , Yang J , Morisseau C , Hammock BD , Freeman BA , Eaton P |
| Ref : Proc Natl Acad Sci U S A , 111 :8167 , 2014 |
| Abstract : |
| PubMedSearch : Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| PubMedID: 24843165 |
| Title : Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase - Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| Author(s) : Charles RL , Rudyk O , Prysyazhna O , Kamynina A , Yang J , Morisseau C , Hammock BD , Freeman BA , Eaton P |
| Ref : Proc Natl Acad Sci U S A , 111 :8167 , 2014 |
| Abstract : |
| PubMedSearch : Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| PubMedID: 24843165 |
| Title : Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase - Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| Author(s) : Charles RL , Rudyk O , Prysyazhna O , Kamynina A , Yang J , Morisseau C , Hammock BD , Freeman BA , Eaton P |
| Ref : Proc Natl Acad Sci U S A , 111 :8167 , 2014 |
| Abstract : |
| PubMedSearch : Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| PubMedID: 24843165 |
| Title : Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation - Charles_2011_Circ.Res_108_324 |
| Author(s) : Charles RL , Burgoyne JR , Mayr M , Weldon SM , Hubner N , Dong H , Morisseau C , Hammock BD , Landar A , Eaton P |
| Ref : Circulation Research , 108 :324 , 2011 |
| Abstract : |
| PubMedSearch : Charles_2011_Circ.Res_108_324 |
| PubMedID: 21164107 |
| Title : Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation - Charles_2011_Circ.Res_108_324 |
| Author(s) : Charles RL , Burgoyne JR , Mayr M , Weldon SM , Hubner N , Dong H , Morisseau C , Hammock BD , Landar A , Eaton P |
| Ref : Circulation Research , 108 :324 , 2011 |
| Abstract : |
| PubMedSearch : Charles_2011_Circ.Res_108_324 |
| PubMedID: 21164107 |
| Title : Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation - Charles_2011_Circ.Res_108_324 |
| Author(s) : Charles RL , Burgoyne JR , Mayr M , Weldon SM , Hubner N , Dong H , Morisseau C , Hammock BD , Landar A , Eaton P |
| Ref : Circulation Research , 108 :324 , 2011 |
| Abstract : |
| PubMedSearch : Charles_2011_Circ.Res_108_324 |
| PubMedID: 21164107 |