| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Allosteric regulation of the soluble epoxide hydrolase by nitro fatty acids using a combined experimental and computational approach - Qiu_2022_J.Mol.Biol__167600 |
| Author(s) : Qiu Q , Abis G , Mattingly-Peck F , Lynham S , Fraternali F , Conte MR |
| Ref : Journal of Molecular Biology , :167600 , 2022 |
| Abstract : |
| PubMedSearch : Qiu_2022_J.Mol.Biol__167600 |
| PubMedID: 35460669 |
| Title : Allosteric regulation of the soluble epoxide hydrolase by nitro fatty acids using a combined experimental and computational approach - Qiu_2022_J.Mol.Biol__167600 |
| Author(s) : Qiu Q , Abis G , Mattingly-Peck F , Lynham S , Fraternali F , Conte MR |
| Ref : Journal of Molecular Biology , :167600 , 2022 |
| Abstract : |
| PubMedSearch : Qiu_2022_J.Mol.Biol__167600 |
| PubMedID: 35460669 |
| Title : Allosteric regulation of the soluble epoxide hydrolase by nitro fatty acids using a combined experimental and computational approach - Qiu_2022_J.Mol.Biol__167600 |
| Author(s) : Qiu Q , Abis G , Mattingly-Peck F , Lynham S , Fraternali F , Conte MR |
| Ref : Journal of Molecular Biology , :167600 , 2022 |
| Abstract : |
| PubMedSearch : Qiu_2022_J.Mol.Biol__167600 |
| PubMedID: 35460669 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation - Charles_2021_Redox.Biol_46_102107 |
| Author(s) : Charles RL , Abis G , Fernandez BF , Guttzeit S , Buccafusca R , Conte MR , Eaton P |
| Ref : Redox Biol , 46 :102107 , 2021 |
| Abstract : |
| PubMedSearch : Charles_2021_Redox.Biol_46_102107 |
| PubMedID: 34509915 |
| Title : Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase - Abis_2019_Anal.Chem_91_14865 |
| Author(s) : Abis G , Pacheco-Gomez R , Bui TTT , Conte MR |
| Ref : Analytical Chemistry , 91 :14865 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Anal.Chem_91_14865 |
| PubMedID: 31660733 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase - Abis_2019_Anal.Chem_91_14865 |
| Author(s) : Abis G , Pacheco-Gomez R , Bui TTT , Conte MR |
| Ref : Analytical Chemistry , 91 :14865 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Anal.Chem_91_14865 |
| PubMedID: 31660733 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase - Abis_2019_Anal.Chem_91_14865 |
| Author(s) : Abis G , Pacheco-Gomez R , Bui TTT , Conte MR |
| Ref : Analytical Chemistry , 91 :14865 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Anal.Chem_91_14865 |
| PubMedID: 31660733 |
| Title : 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism - Abis_2019_Commun.Biol_2_188 |
| Author(s) : Abis G , Charles RL , Kopec J , Yue WW , Atkinson RA , Bui TTT , Lynham S , Popova S , Sun YB , Fraternali F , Eaton P , Conte MR |
| Ref : Commun Biol , 2 :188 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Commun.Biol_2_188 |
| PubMedID: 31123712 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |
| Title : Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain - Abis_2019_Protein.Expr.Purif_153_105 |
| Author(s) : Abis G , Charles RL , Eaton P , Conte MR |
| Ref : Protein Expr Purif , 153 :105 , 2019 |
| Abstract : |
| PubMedSearch : Abis_2019_Protein.Expr.Purif_153_105 |
| PubMedID: 30218745 |