7VJT
Name : Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8
Revelation date : 28-Sep-2022
Family : Thioesterase
Gene_locus : myctu-PKS13
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhang, W., Wang, S.S., Yu, L.F.
Ligand : Inhibitor Coumestan-cpd8 Ligand in structure: Ligplot
References (1)
| Title : Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment - Zhang_2022_J.Med.Chem_65_13240 |
| Author(s) : Zhang W , Lun S , Wang SS , Cai YP , Yang F , Tang J , Bishai WR , Yu LF |
| Ref : Journal of Medicinal Chemistry , 65 :13240 , 2022 |
| Abstract : |
| PubMedSearch : Zhang_2022_J.Med.Chem_65_13240 |
| PubMedID: 36174223 |
| Gene_locus related to this paper: myctu-PKS13 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 7VJT Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 7VJT Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 7VJT Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 7VJT 3D, interactive encyclopedia of proteins - PROTEOPEDIA server