8BT5
Name : Structure of the human Wnt deacylase Notum in complex with ARUK3004877
Revelation date : 14-Dec-2022
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhao, Y.,Jones, E.Y.,Fish, P.
Ligand : Inhibitor ARUK3004877 Ligand in structure: Ligplot
References (1)
| Title : Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity - Atkinson_2023_Eur.J.Med.Chem_251_115132 |
| Author(s) : Atkinson BN , Willis NJ , Zhao Y , Patel C , Frew S , Costelloe K , Magno L , Svensson F , Jones EY , Fish PV |
| Ref : Eur Journal of Medicinal Chemistry , 251 :115132 , 2023 |
| Abstract : |
| PubMedSearch : Atkinson_2023_Eur.J.Med.Chem_251_115132 |
| PubMedID: 36934521 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 8BT5 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 8BT5 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 8BT5 Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 8BT5 3D, interactive encyclopedia of proteins - PROTEOPEDIA server