Magno L

Title : Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity - Atkinson_2023_Eur.J.Med.Chem_251_115132

Author(s) : Atkinson BN , Willis NJ , Zhao Y , Patel C , Frew S , Costelloe K , Magno L , Svensson F , Jones EY , Fish PV

Ref : Eur Journal of Medicinal Chemistry , 251 :115132 , 2023

Abstract :

PubMedSearch : Atkinson_2023_Eur.J.Med.Chem_251_115132

PubMedID: 36934521

Gene_locus related to this paper: human-NOTUM

Title : Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity - Steadman_2022_J.Med.Chem_65_562

Author(s) : Steadman D , Atkinson BN , Zhao Y , Willis NJ , Frew S , Monaghan A , Patel C , Armstrong E , Costelloe K , Magno L , Bictash M , Jones EY , Fish PV , Svensson F

Ref : Journal of Medicinal Chemistry , 65 :562 , 2022

Abstract :

PubMedSearch : Steadman_2022_J.Med.Chem_65_562

PubMedID: 34939789

Gene_locus related to this paper: human-NOTUM

Magno L

References (2)

1. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity - Atkinson_2023_Eur.J.Med.Chem_251_115132

2. Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity - Steadman_2022_J.Med.Chem_65_562