Name : Structure of the human Wnt deacylase Notum in complex with ARUK3004552

Revelation date : 14-Dec-2022

Family : Pectinacetylesterase-Notum

Gene_locus : human-NOTUM

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Zhao, Y.,Jones, E.Y.,Fish, P.

Ligand :

References (1)

Title : Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity - Atkinson_2023_Eur.J.Med.Chem_251_115132
Author(s) : Atkinson BN , Willis NJ , Zhao Y , Patel C , Frew S , Costelloe K , Magno L , Svensson F , Jones EY , Fish PV
Ref : Eur Journal of Medicinal Chemistry , 251 :115132 , 2023
PubMedID: 36934521
Gene_locus related to this paper: human-NOTUM

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 8BTH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 8BTH Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 8BTH Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 8BTH 3D, interactive encyclopedia of proteins - PROTEOPEDIA server