8QZD
Name : Soluble epoxide hydrolase in complex with Epoxykinin
Revelation date : 28-Feb-2024
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Kumar, A.,Ehrler, J.M.H.,Ziegler, S.,Doetsch, L.,Proschak, E.,Knapp, S.,Structural Genomics Consortium (SGC)
Ligand : Inhibitor Epoxykinin Ligand in structure: Ligplot
References (1)
| Title : Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator - Dotsch_2024_J.Med.Chem__ |
| Author(s) : Dotsch L , Davies C , Hennes E , Schonfeld J , Kumar A , Guita C , Ehrler JHM , Hiesinger K , Thavam S , Janning P , Sievers S , Knapp S , Proschak E , Ziegler S , Waldmann H |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Dotsch_2024_J.Med.Chem__ |
| PubMedID: 38470246 |
| Gene_locus related to this paper: human-EPHX2 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 8QZD Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 8QZD Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 8QZD Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 8QZD 3D, interactive encyclopedia of proteins - PROTEOPEDIA server