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Structure Report for: 1YA8

NameCrystal Structure of Human Liver Carboxylesterase in complex with Mevastatin
Revelation date02-Aug-2005
FamilyCarb_B_Chordata: there are 543 genes in this family, 20 structure(s)
Gene_locushuman-CES1
PDB FileESTHER: header of PDB entry RCSB: Full entry
CommentFleming, C.D., Bencharit, S., Edwards, C.C., Hyatt, J.L., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Reference
    Title: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
    Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard-Williams EL and Redinbo MR <1 more author(s)>
    Ref: Journal of Molecular Biology, 352:165, 2005 : PubMed

            

LigandInhibitor: Mevastatin Ligand in structure: Ligplot
Representative scheme of Carb_B_Chordata structure and an image from PDBsum server
Databases
PDB-Sum1YA8 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP1YA8 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP1YA8 Structural Classification Of Protein - SCOP server
PROTEOPEDIA1ya8 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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