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Structure Report for: 5LZ9

Name|Fragment-based inhibitors of human Lipoprotein associated Phospholipase A2
Revelation date|21-Dec-2016
Family|PAF-Acetylhydrolase: there are 145 genes in this family, 35 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Woolford, A.J-A, Day, P.J.
Ligand|Inhibitor: 5LZ9-7BR Ligand in structure: Ligplot


    Title: Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
    Woolford AJ, Day PJ, Beneton V, Berdini V, Coyle JE, Dudit Y, Grondin P, Huet P, Lee LY and Zhang X <11 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:10738, 2016 : PubMed


Representative scheme of PAF-Acetylhydrolase structure and an image from PDBsum server


PDB-Sum5LZ9 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5LZ9 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5LZ9 Structural Classification Of Protein - SCOP server
PROTEOPEDIA5lz9 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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