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Structure Report for: 6CQW

Name|Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with VX(-) and HI-6
Revelation date|05-Dec-2018
Family|ACHE: there are 546 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Bester, S.M., Guelta, M.A., Pegan, S.D., Height, J.J. (replaces 5VLT withdrawn)
Ligand|Inhibitor: VX Ligand in structure: Ligplot Reactivator: HI-6 Ligand in structure: Ligplot


    Title: Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6
    Bester SM, Guelta MA, Cheung J, Winemiller MD, Bae SY, Myslinski J, Pegan SD, Height JJ
    Ref: Chemical Research in Toxicology, 31:1405, 2018 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6CQW Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6CQW Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6CQW Structural Classification Of Protein - SCOP server
PROTEOPEDIA6cqw 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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