Cheung J

Title : Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6 - McGuire_2021_Chem.Res.Toxicol_34_804

Author(s) : McGuire JR , Bester SM , Guelta MA , Cheung J , Langley C , Winemiller MD , Bae SY , Funk V , Myslinski JM , Pegan SD , Height JJ

Ref : Chemical Research in Toxicology , 34 :804 , 2021

Abstract :

PubMedSearch : McGuire_2021_Chem.Res.Toxicol_34_804

PubMedID: 33538594

Gene_locus related to this paper: human-ACHE

Title : Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups - Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

Author(s) : Rosenberry TL , Cheung J

Ref : Chemico-Biological Interactions , : , 2019

Abstract :

PubMedSearch : Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

PubMedID: 31175846

Title : beta2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure - Vanhaesebrouck_2019_Brain_142_3713

Author(s) : Vanhaesebrouck AE , Webster R , Maxwell S , Rodriguez Cruz PM , Cossins J , Wickens J , Liu WW , Cetin H , Cheung J , Ramjattan H , Palace J , Beeson D

Ref : Brain , 142 :3713 , 2019

Abstract :

PubMedSearch : Vanhaesebrouck_2019_Brain_142_3713

PubMedID: 31633155

Title : The structural and biochemical impacts of monomerizing human acetylcholinesterase - Bester_2019_Protein.Sci_28_1106

Author(s) : Bester SM , Adipietro KA , Funk VL , Myslinski JM , Keul ND , Cheung J , Wilder PT , Wood ZA , Weber DJ , Height JJ , Pegan SD

Ref : Protein Science , 28 :1106 , 2019

Abstract :

PubMedSearch : Bester_2019_Protein.Sci_28_1106

PubMedID: 30993792

Gene_locus related to this paper: human-ACHE

Title : Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance - Cheung_2018_Structure_26_130

Author(s) : Cheung J , Mahmood A , Kalathur R , Liu L , Carlier PR

Ref : Structure , 26 :130 , 2018

Abstract :

PubMedSearch : Cheung_2018_Structure_26_130

PubMedID: 29276037

Gene_locus related to this paper: anoga-ACHE1

Title : Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6 - Bester_2018_Chem.Res.Toxicol_31_1405

Author(s) : Bester SM , Guelta MA , Cheung J , Winemiller MD , Bae SY , Myslinski J , Pegan SD , Height JJ

Ref : Chemical Research in Toxicology , 31 :1405 , 2018

Abstract :

PubMedSearch : Bester_2018_Chem.Res.Toxicol_31_1405

PubMedID: 30462502

Gene_locus related to this paper: human-ACHE

Title : A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants - Pilkington_2018_BMC.Genomics_19_257

Author(s) : Pilkington SM , Crowhurst R , Hilario E , Nardozza S , Fraser L , Peng Y , Gunaseelan K , Simpson R , Tahir J , Deroles SC , Templeton K , Luo Z , Davy M , Cheng C , McNeilage M , Scaglione D , Liu Y , Zhang Q , Datson P , De Silva N , Gardiner SE , Bassett H , Chagne D , McCallum J , Dzierzon H , Deng C , Wang YY , Barron L , Manako K , Bowen J , Foster TM , Erridge ZA , Tiffin H , Waite CN , Davies KM , Grierson EP , Laing WA , Kirk R , Chen X , Wood M , Montefiori M , Brummell DA , Schwinn KE , Catanach A , Fullerton C , Li D , Meiyalaghan S , Nieuwenhuizen N , Read N , Prakash R , Hunter D , Zhang H , McKenzie M , Knabel M , Harris A , Allan AC , Gleave A , Chen A , Janssen BJ , Plunkett B , Ampomah-Dwamena C , Voogd C , Leif D , Lafferty D , Souleyre EJF , Varkonyi-Gasic E , Gambi F , Hanley J , Yao JL , Cheung J , David KM , Warren B , Marsh K , Snowden KC , Lin-Wang K , Brian L , Martinez-Sanchez M , Wang M , Ileperuma N , Macnee N , Campin R , McAtee P , Drummond RSM , Espley RV , Ireland HS , Wu R , Atkinson RG , Karunairetnam S , Bulley S , Chunkath S , Hanley Z , Storey R , Thrimawithana AH , Thomson S , David C , Testolin R , Huang H , Hellens RP , Schaffer RJ

Ref : BMC Genomics , 19 :257 , 2018

Abstract :

PubMedSearch : Pilkington_2018_BMC.Genomics_19_257

PubMedID: 29661190

Gene_locus related to this paper: actde-CXE3 , actde-CXE5 , actch-a0a2r6p9v4 , actch-a0a2r6phk8 , actch-a0a2r6pty2 , actch-q0zpu6 , actcc-a0a2r6q553 , actcc-a0a2r6quq2 , actcc-a0a2r6q2m9 , actcc-a0a2r6q2n7 , actcc-a0a2r6ru97 , actcc-a0a2r6r3e8 , actcc-a0a2r6qy24 , actcc-a0a2r6pzy5 , actcc-a0a2r6p5n3 , actcc-a0a2r6qdp0 , actcc-a0a2r6qgs9

Title : Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface - Franklin_2016_Proteins_84_1246

Author(s) : Franklin MC , Rudolph MJ , Ginter C , Cassidy MS , Cheung J

Ref : Proteins , 84 :1246 , 2016

Abstract :

PubMedSearch : Franklin_2016_Proteins_84_1246

PubMedID: 27191504

Gene_locus related to this paper: human-ACHE

Title : Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence - Rosenberry_2016_Chem.Biol.Interact_259_78

Author(s) : Rosenberry TL , Martin PK , Nix AJ , Wildman SA , Cheung J , Snyder SA , Tan RX

Ref : Chemico-Biological Interactions , 259 :78 , 2016

Abstract :

PubMedSearch : Rosenberry_2016_Chem.Biol.Interact_259_78

PubMedID: 27297626

Title : Structural genomics for drug design against the pathogen Coxiella burnetii - Franklin_2015_Proteins_83_2124

Author(s) : Franklin MC , Cheung J , Rudolph MJ , Burshteyn F , Cassidy M , Gary E , Hillerich B , Yao ZK , Carlier PR , Totrov M , Love JD

Ref : Proteins , 83 :2124 , 2015

Abstract :

PubMedSearch : Franklin_2015_Proteins_83_2124

PubMedID: 26033498

Gene_locus related to this paper: coxbu-CBU1769

Title : Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination - Cheung_2014_J.Mol.Neurosci_53_506

Author(s) : Cheung J , Beri V , Shiomi K , Rosenberry TL

Ref : Journal of Molecular Neuroscience , 53 :506 , 2014

Abstract :

PubMedSearch : Cheung_2014_J.Mol.Neurosci_53_506

PubMedID: 24573600

Title : The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity - Beri_2013_Biochemistry_52_7486

Author(s) : Beri V , Wildman SA , Shiomi K , Al-Rashid ZF , Cheung J , Rosenberry TL

Ref : Biochemistry , 52 :7486 , 2013

Abstract :

PubMedSearch : Beri_2013_Biochemistry_52_7486

PubMedID: 24040835

Title : Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility - Cheung_2013_ACS.Med.Chem.Lett_4_1091

Author(s) : Cheung J , Gary EN , Shiomi K , Rosenberry TL

Ref : ACS Med Chem Lett , 4 :1091 , 2013

Abstract :

PubMedSearch : Cheung_2013_ACS.Med.Chem.Lett_4_1091

PubMedID: 24900610

Gene_locus related to this paper: human-ACHE

Title : Structures of human acetylcholinesterase in complex with pharmacologically important ligands - Cheung_2012_J.Med.Chem_55_10282

Author(s) : Cheung J , Rudolph MJ , Burshteyn F , Cassidy MS , Gary EN , Love J , Franklin MC , Height JJ

Ref : Journal of Medicinal Chemistry , 55 :10282 , 2012

Abstract :

PubMedSearch : Cheung_2012_J.Med.Chem_55_10282

PubMedID: 23035744

Gene_locus related to this paper: human-ACHE

Title : Crystal structure of a functional dimer of the PhoQ sensor domain - Cheung_2008_J.Biol.Chem_283_13762

Author(s) : Cheung J , Bingman CA , Reyngold M , Hendrickson WA , Waldburger CD

Ref : Journal of Biological Chemistry , 283 :13762 , 2008

Abstract :

PubMedSearch : Cheung_2008_J.Biol.Chem_283_13762

PubMedID: 18348979

Title : Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans - Wen_2003_Hum.Mol.Genet_12_1131

Author(s) : Wen XY , Hegele RA , Wang J , Wang DY , Cheung J , Wilson M , Yahyapour M , Bai Y , Zhuang L , Skaug J , Young TK , Connelly PW , Koop BF , Tsui LC , Stewart AK

Ref : Hum Mol Genet , 12 :1131 , 2003

Abstract :

PubMedSearch : Wen_2003_Hum.Mol.Genet_12_1131

PubMedID: 12719377

Gene_locus related to this paper: human-LIPI

Cheung J

General

References (16)

Cheung J

General

References (16)

1. Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6 - McGuire_2021_Chem.Res.Toxicol_34_804

2. Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups - Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

3. beta2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure - Vanhaesebrouck_2019_Brain_142_3713

4. The structural and biochemical impacts of monomerizing human acetylcholinesterase - Bester_2019_Protein.Sci_28_1106

5. Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance - Cheung_2018_Structure_26_130

6. Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6 - Bester_2018_Chem.Res.Toxicol_31_1405

7. A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants - Pilkington_2018_BMC.Genomics_19_257

8. Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface - Franklin_2016_Proteins_84_1246

9. Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence - Rosenberry_2016_Chem.Biol.Interact_259_78

10. Structural genomics for drug design against the pathogen Coxiella burnetii - Franklin_2015_Proteins_83_2124

11. Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination - Cheung_2014_J.Mol.Neurosci_53_506

12. The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity - Beri_2013_Biochemistry_52_7486

13. Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility - Cheung_2013_ACS.Med.Chem.Lett_4_1091

14. Structures of human acetylcholinesterase in complex with pharmacologically important ligands - Cheung_2012_J.Med.Chem_55_10282

15. Crystal structure of a functional dimer of the PhoQ sensor domain - Cheung_2008_J.Biol.Chem_283_13762

16. Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans - Wen_2003_Hum.Mol.Genet_12_1131