[18F]BMP
1-methyl-4-piperidyl-4'-fluorobenzoate is not a substrate for AChE, and thus not suitable as an in vivo radiotracer for studying this enzyme in the brain. 1-methyl-4-piperidinyl p-fluorobenzoate (BMP) is a substrate for BChE, not AChE
General
Type : PET probe, Piperidine, Benzoate
Chemical_Nomenclature : (1-methylpiperidin-4-yl) 4-fluorobenzoate
Canonical SMILES : CN1CCC(CC1)OC(=O)C2=CC=C(C=C2)F
InChI : InChI=1S\/C13H16FNO2\/c1-15-8-6-12(7-9-15)17-13(16)10-2-4-11(14)5-3-10\/h2-5,12H,6-9H2,1H3
InChIKey : WVLAEJNDCHGGDI-UHFFFAOYSA-N
Other name(s) : 1-Methyl-4-piperidyl 4'-fluorobenzoate || M4P 4'-Fluorobenzoate || DTXSID90145459 || RefChem:76332 || CHEMBL37274 || SCHEMBL1844575 || BMP
MW : 237.27
Formula : C13H16FNO2
CAS_number : 102698-53-3
PubChem : 128156
UniChem : WVLAEJNDCHGGDI-UHFFFAOYSA-N
Target
Structures : No structure
Families : BCHE
References (2)
| Title : Molecular Imaging of Butyrylcholinesterase Associated with Amyloid-beta Plaques Distinguishes 5XFAD from Wild-Type Mice: A Proof-of-Concept - Reid_2026_Mol.Imaging.Biol__ |
| Author(s) : Reid GA , DeBay DR , Macdonald IR , Laouz AB , Pottie IR , Darvesh S |
| Ref : Mol Imaging Biol , : , 2026 |
| Abstract : |
| PubMedSearch : Reid_2026_Mol.Imaging.Biol__ |
| PubMedID: 42209955 |
| Gene_locus related to this paper: human-BCHE |
| Title : Synthesis of carbon-11- and fluorine-18-labeled 1-methyl-4-piperidyl-4'-fluorobenzoate and their biodistribution in mice - Bormans_1996_Nucl.Med.Biol_23_513 |
| Author(s) : Bormans G , Sherman P , Snyder SE , Kilbourn MR |
| Ref : Nucl Med Biol , 23 :513 , 1996 |
| Abstract : |
| PubMedSearch : Bormans_1996_Nucl.Med.Biol_23_513 |
| PubMedID: 8832709 |