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Piperidine

Heterocyclic amine consisting of a six-membered ring containing five methylene bridges (CH2) and one amine bridge (NH). Building block for many inhibitors of enzymes
Substrate Main targeted enzyme families Type Structure
G1M9-va-JW972 Carb_B_Chordata pNP Triazol Carbamate Piperidine Carbohydrate
Evategrel Not AlphaBeta Hydrolase target Drug Pro-Drug Piperidine Acetate Antiplatelet Sulfur Compound Organochlorine
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine Organochlorine
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperidine Antibiotic
Methylphenidate Carb_B_Chordata Piperidine Not AlphaBeta Hydrolase target Drug
Nap-FY-CPT Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine Peptide
NPC Carb_B_Bacteria Carbamate Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not AlphaBeta Hydrolase target
[18F]FEtP4A Piperidine PET probe
[11C]-PMP ACHE Piperidine PET probe Propionate
[11C]-MP4A ACHE Acetate Piperidine PET probe
Niraparib Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Imidazole Piperidine Carboxamide Indazole
G1M9-va-JW972 Carb_B_Chordata pNP Triazol Carbamate Piperidine Carbohydrate
Evategrel Not AlphaBeta Hydrolase target Drug Pro-Drug Piperidine Acetate Antiplatelet Sulfur Compound Organochlorine
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine Organochlorine
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperidine Antibiotic
Methylphenidate Carb_B_Chordata Piperidine Not AlphaBeta Hydrolase target Drug
Nap-FY-CPT Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine Peptide
NPC Carb_B_Bacteria Carbamate Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not AlphaBeta Hydrolase target
[18F]FEtP4A Piperidine PET probe
[11C]-PMP ACHE Piperidine PET probe Propionate
[11C]-MP4A ACHE Acetate Piperidine PET probe
Niraparib Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Imidazole Piperidine Carboxamide Indazole
G1M9-va-JW972 Carb_B_Chordata pNP Triazol Carbamate Piperidine Carbohydrate
Evategrel Not AlphaBeta Hydrolase target Drug Pro-Drug Piperidine Acetate Antiplatelet Sulfur Compound Organochlorine
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine Organochlorine
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperidine Antibiotic
Methylphenidate Carb_B_Chordata Piperidine Not AlphaBeta Hydrolase target Drug
Nap-FY-CPT Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine Peptide
NPC Carb_B_Bacteria Carbamate Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not AlphaBeta Hydrolase target
[18F]FEtP4A Piperidine PET probe
[11C]-PMP ACHE Piperidine PET probe Propionate
[11C]-MP4A ACHE Acetate Piperidine PET probe