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Piperidine

Heterocyclic amine consisting of a six-membered ring containing five methylene bridges (CH2) and one amine bridge (NH). Building block for many inhibitors of enzymes
Substrate Main targeted enzyme families Type Structure
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperidine Antibiotic
Methylphenidate Carb_B_Chordata Piperidine Not AlphaBeta Hydrolase target Drug
Nap-FY-CPT Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine Peptide
NPC Carb_B_Bacteria Carbamate Drug Pro-Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not AlphaBeta Hydrolase target
[18F]FEtP4A Piperidine PET probe
[11C]-PMP ACHE Piperidine PET probe Propionate
[11C]-MP4A ACHE Acetate Piperidine PET probe