Macdonald IR

General

Full name : Macdonald Ian R

First name : Ian R

Mail : Dalhousie University\; Anatomy & Neurobiology\; Rm 12D\; 5850 College Street\; PO Box 15000\; Halifax

Zip Code :

City :

Country : Canada

Email : Ian.Macdonald@dal.ca

Phone : +19024942007

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References (10)

Title : Butyrylcholinesterase-knockout reduces fibrillar beta-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease - DeBay_2017_Brain.Res_1671_102
Author(s) : DeBay DR , Reid GA , Macdonald IR , Mawko G , Burrell S , Martin E , Bowen CV , Darvesh S
Ref : Brain Research , 1671 :102 , 2017
PubMedID: 28729192

Title : Quantification of Butyrylcholinesterase Activity as a Sensitive and Specific Biomarker of Alzheimer's Disease - Macdonald_2017_J.Alzheimers.Dis_58_491
Author(s) : Macdonald IR , Maxwell SP , Reid GA , Cash MK , DeBay DR , Darvesh S
Ref : J Alzheimers Dis , 58 :491 , 2017
PubMedID: 28453492

Title : Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study - Rosenberry_2017_Molecules_22_
Author(s) : Rosenberry TL , Brazzolotto X , Macdonald IR , Wandhammer M , Trovaslet-Leroy M , Darvesh S , Nachon F
Ref : Molecules , 22 : , 2017
PubMedID: 29186056
Gene_locus related to this paper: human-BCHE

Title : Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology - Macdonald_2016_J.Nucl.Med_57_297
Author(s) : Macdonald IR , Reid GA , Pottie IR , Martin E , Darvesh S
Ref : J Nucl Med , 57 :297 , 2016
PubMedID: 26541777

Title : Cholinesterase inhibition in Alzheimer's disease: is specificity the answer? - Macdonald_2014_J.Alzheimers.Dis_42_379
Author(s) : Macdonald IR , Rockwood K , Martin E , Darvesh S
Ref : J Alzheimers Dis , 42 :379 , 2014
PubMedID: 24898642

Title : Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems - Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822
Author(s) : Darvesh S , Macdonald IR , Martin E
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3822 , 2013
PubMedID: 23707254

Title : Thioesters for the in vitro evaluation of agents to image brain cholinesterases - Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447
Author(s) : Macdonald IR , Jollymore CT , Reid GA , Pottie IR , Martin E , Darvesh S
Ref : J Enzyme Inhib Med Chem , 28 :447 , 2013
PubMedID: 22233541

Title : Probing the peripheral site of human butyrylcholinesterase - Macdonald_2012_Biochemistry_51_7046
Author(s) : Macdonald IR , Martin E , Rosenberry TL , Darvesh S
Ref : Biochemistry , 51 :7046 , 2012
PubMedID: 22901043

Title : Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase - Macdonald_2011_Mol.Imaging.Biol_13_1250
Author(s) : Macdonald IR , Reid GA , Joy EE , Pottie IR , Matte G , Burrell S , Mawko G , Martin E , Darvesh S
Ref : Mol Imaging Biol , 13 :1250 , 2011
PubMedID: 20976626

Title : Butyrylcholinesterase activity in multiple sclerosis neuropathology - Darvesh_2010_Chem.Biol.Interact_187_425
Author(s) : Darvesh S , Leblanc AM , Macdonald IR , Reid GA , Bhan V , Macaulay RJ , Fisk JD
Ref : Chemico-Biological Interactions , 187 :425 , 2010
PubMedID: 20122907