17,18-EEQ

General

Type : Epoxy-fatty-acid, Fatty acid

Chemical_Nomenclature : (5Z,8Z,11Z,14Z)-16-[(2R,3S)-3-ethyloxiran-2-yl]hexadeca-5,8,11,14-tetraenoic acid, (5Z,8Z,11Z,14Z)-16-[(2S,3R)-3-ethyloxiran-2-yl]hexadeca-5,8,11,14-tetraenoic acid

Canonical SMILES : CCC1C(O1)CC=CCC=CCC=CCC=CCCCC(=O)O

InChI : InChI=1S\/C20H30O3\/c1-2-18-19(23-18)16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-20(21)22\/h3,5-6,8-9,11-12,14,18-19H,2,4,7,10,13,15-17H2,1H3,(H,21,22)\/b5-3-,8-6-,11-9-,14-12-\/t18-,19+\/m0\/s1 || InChI=1S\/C20H30O3\/c1-2-18-19(23-18)16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-20(21)22\/h3,5-6,8-9,11-12,14,18-19H,2,4,7,10,13,15-17H2,1H3,(H,21,22)\/b5-3-,8-6-,11-9-,14-12-\/t18-,19+\/m1\/s1

InChIKey : GPQVVJQEBXAKBJ-VDTDYMMTSA-N || GPQVVJQEBXAKBJ-YQLHGUCYSA-N

Other name(s) : 17,18-Epoxyeicosatetraenoic acid  ||  17R,18S-EpETE  ||  17(R),18(S)-EETeTr  ||  CHEBI:76953  ||  (5Z,8Z,11Z,14Z)-(17R,18S)-17,18-Epoxyicosa-5,8,11,14-tetraenoic acid  ||  17R,18S-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid  ||  CHEMBL1802675  ||  (+\/-)17(18)-EpETE  ||  17(S),18(R)-EETeTr  ||  CHEBI:76955  ||  17,18-EETeTr  ||  17(18)-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid  ||  CHEMBL1802676


MW : 318.4

Formula : C20H30O3

CAS_number :

PubChem : 5282277,    27076755

UniChem : GPQVVJQEBXAKBJ-VDTDYMMTSA-N,    GPQVVJQEBXAKBJ-YQLHGUCYSA-N

Target

Families : Epoxide_hydrolase

References (2)

Title : Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice - Yang_2021_Int.J.Mol.Sci_22_
Author(s) : Yang Y , Xu X , Wu H , Yang J , Chen J , Morisseau C , Hammock BD , Bettaieb A , Zhao L
Ref : Int J Mol Sci , 22 : , 2021
Abstract :
PubMedSearch : Yang_2021_Int.J.Mol.Sci_22_
PubMedID: 34361032

Title : Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation - McReynolds_2020_Adv.Exp.Med.Biol_1274_71
Author(s) : McReynolds C , Morisseau C , Wagner K , Hammock B
Ref : Advances in Experimental Medicine & Biology , 1274 :71 , 2020
Abstract :
PubMedSearch : McReynolds_2020_Adv.Exp.Med.Biol_1274_71
PubMedID: 32894508