Ac-Ala-pNA

General

Type : Peptide, p-nitroaniline, pNP, Chromogen

Chemical_Nomenclature : (2S)-2-acetamido-N-(4-nitrophenyl)propanamide

Canonical SMILES : C[C@@H](C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C

InChI : InChI=1S\/C11H13N3O4\/c1-7(12-8(2)15)11(16)13-9-3-5-10(6-4-9)14(17)18\/h3-7H,1-2H3,(H,12,15)(H,13,16)\/t7-\/m0\/s1

InChIKey : ABYZSYDGJGVCHS-ZETCQYMHSA-N

Other name(s) : AANA  ||  Acetylalanine 4-nitroanilide  ||  Acala-pna  ||  DTXSID10189532  ||  N-Acetyl-L-alanine 4-nitroanilide  ||  N-acetyl-L-alanine-P-nitroanilide  ||  SCHEMBL2681740


MW : 251.24

Formula : C11H13N3O4

CAS_number : 35978-75-7

PubChem : 169741

UniChem : ABYZSYDGJGVCHS-ZETCQYMHSA-N

Target

Structures : No structure

Families : ACPH_Peptidase_S9

References (5)

Title : Ligand binding Pro-miscuity of acylpeptide hydrolase, structural analysis of a detoxifying serine hydrolase - Kiss-Szeman_2025_Protein.Sci_34_e70320
Author(s) : Kiss-Szeman AJ , Takacs L , Jakli I , Banoczi Z , Hosogi N , Traore DAK , Harmat V , Perczel A , Menyhard DK
Ref : Protein Science , 34 :e70320 , 2025
Abstract :
PubMedSearch : Kiss-Szeman_2025_Protein.Sci_34_e70320
PubMedID: 41074793

Title : Molecular cloning, expression and characterization of acylpeptide hydrolase in the silkworm, Bombyx mori - Fu_2016_Gene_580_8
Author(s) : Fu P , Sun W , Zhang Z
Ref : Gene , 580 :8 , 2016
Abstract :
PubMedSearch : Fu_2016_Gene_580_8
PubMedID: 26778207
Gene_locus related to this paper: bommo-acph

Title : Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide - Yamin_2009_Mol.Neurodegener_4_33
Author(s) : Yamin R , Zhao C , O'Connor PB , McKee AC , Abraham CR
Ref : Mol Neurodegener , 4 :33 , 2009
Abstract :
PubMedSearch : Yamin_2009_Mol.Neurodegener_4_33
PubMedID: 19627603
Gene_locus related to this paper: ratno-acph

Title : Acylaminoacyl-peptidase -
Author(s) : Jones WM , Scaloni A , Manning JM
Ref : Methods Enzymol , 244 :227 , 1994
PubMedID: 7845211

Title : Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction - Kobayashi_1987_J.Biol.Chem_262_11435
Author(s) : Kobayashi K , Smith JA
Ref : Journal of Biological Chemistry , 262 :11435 , 1987
Abstract :
PubMedSearch : Kobayashi_1987_J.Biol.Chem_262_11435
PubMedID: 3305492
Gene_locus related to this paper: ratno-acph