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ratno-acph

Rattus norvegicus (Rat) Acyl-peptide hydrolase; Acylamino-acid-releasing enzyme

Comment

Belongs to peptidase family s9C

Relationship

Family : ACPH_Peptidase_S9

Block : X

Position in NCBI Life Tree : Rattus norvegicus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Rattus N E > Rattus norvegicus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MERQVLLSEP QEAAALYRGL SRQPSLSAAC LGPEVTTQYG GLYRTVHTEW TQRDLERMEN IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTVSGEEKQF LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK ALDISASDDE MARPKKPDQA IKGDQFVFYE DWGETMVSKS IPVLCVLDID SGNISVLEGV PENVSPGQAF WAPGDTGVVF VGWWHEPFRL GIRYCTNRRS ALYYVDLSGG KCELLSDGSL AICSPRLSPD QCRIVYLQYP CLAPHHQCSQ LCLYDWYTKV TSVVVDIVPR QLGESFSGIY CSLLPLGCWS ADSQRVVFDS AQRSRQDLFA VDTQTGSITS LTAAGSAGSW KLLTIDKDLM VAQFSTPSLP PSLKVGFLPP PGKEQSVSWV SLEEAEPIPG IHWGVRVLHP PPDQENVQYA DLDFEAILLQ PSNPPDKTQV PMVVMPHGGP HSSFVTAWML FPAMLCKMGF AVLLVNYRGS TGFGQDSILS LPGNVGHQDV KDVQFAVEQV LQEEHFDARR VALMGGSHGG FLSCHLIGQY PETYSACIAR NPVINIASMM GSTDIPDWCM VETGFPYSNS CLPDLNVWEE MLDKSPIKYI PQVKTPVLLM LGQEDRRVPF KQGMEYYRAL KARNVPVRLL LYPKSNHALS EVEAESDSFM NAVLWLHTHL GS

References (5)

Title : Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide - Yamin_2009_Mol.Neurodegener_4_33
Author(s) : Yamin R , Zhao C , O'Connor PB , McKee AC , Abraham CR
Ref : Mol Neurodegener , 4 :33 , 2009
Abstract :
PubMedSearch : Yamin_2009_Mol.Neurodegener_4_33
PubMedID: 19627603
Gene_locus related to this paper: ratno-acph

Title : Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide - Yamin_2007_J.Neurochem_100_458
Author(s) : Yamin R , Bagchi S , Hildebrant R , Scaloni A , Widom RL , Abraham CR
Ref : Journal of Neurochemistry , 100 :458 , 2007
Abstract :
PubMedSearch : Yamin_2007_J.Neurochem_100_458
PubMedID: 17241160
Gene_locus related to this paper: ratno-acph

Title : The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) - Gerhard_2004_Genome.Res_14_2121
Author(s) : Gerhard DS , Wagner L , Feingold EA , Shenmen CM , Grouse LH , Schuler G , Klein SL , Old S , Rasooly R , Good P , Guyer M , Peck AM , Derge JG , Lipman D , Collins FS , Jang W , Sherry S , Feolo M , Misquitta L , Lee E , Rotmistrovsky K , Greenhut SF , Schaefer CF , Buetow K , Bonner TI , Haussler D , Kent J , Kiekhaus M , Furey T , Brent M , Prange C , Schreiber K , Shapiro N , Bhat NK , Hopkins RF , Hsie F , Driscoll T , Soares MB , Casavant TL , Scheetz TE , Brown-stein MJ , Usdin TB , Toshiyuki S , Carninci P , Piao Y , Dudekula DB , Ko MS , Kawakami K , Suzuki Y , Sugano S , Gruber CE , Smith MR , Simmons B , Moore T , Waterman R , Johnson SL , Ruan Y , Wei CL , Mathavan S , Gunaratne PH , Wu J , Garcia AM , Hulyk SW , Fuh E , Yuan Y , Sneed A , Kowis C , Hodgson A , Muzny DM , McPherson J , Gibbs RA , Fahey J , Helton E , Ketteman M , Madan A , Rodrigues S , Sanchez A , Whiting M , Madari A , Young AC , Wetherby KD , Granite SJ , Kwong PN , Brinkley CP , Pearson RL , Bouffard GG , Blakesly RW , Green ED , Dickson MC , Rodriguez AC , Grimwood J , Schmutz J , Myers RM , Butterfield YS , Griffith M , Griffith OL , Krzywinski MI , Liao N , Morin R , Palmquist D , Petrescu AS , Skalska U , Smailus DE , Stott JM , Schnerch A , Schein JE , Jones SJ , Holt RA , Baross A , Marra MA , Clifton S , Makowski KA , Bosak S , Malek J
Ref : Genome Res , 14 :2121 , 2004
Abstract :
PubMedSearch : Gerhard_2004_Genome.Res_14_2121
PubMedID: 15489334
Gene_locus related to this paper: human-AFMID , human-CES4A , human-CES5A , human-NOTUM , human-SERAC1 , human-SERHL2 , human-TMEM53 , mouse-acot1 , mouse-adcl4 , mouse-Ces2f , mouse-Ces4a , mouse-notum , mouse-q6wqj1 , mouse-Q9DAI6 , mouse-rbbp9 , mouse-SERHL , mouse-srac1 , mouse-tmm53 , rat-abhd6 , rat-abhda , rat-abhea , rat-abheb , rat-Ldah , rat-cd029 , rat-estd , rat-Kansl3 , rat-nceh1 , ratno-acph , ratno-CMBL , mouse-b2rwd2 , rat-b5den3 , rat-ab17c , human-cb069

Title : Cloning and sequence analysis of a rat liver cDNA encoding acyl-peptide hydrolase - Kobayashi_1989_J.Biol.Chem_264_8892
Author(s) : Kobayashi K , Lin LW , Yeadon JE , Klickstein LB , Smith JA
Ref : Journal of Biological Chemistry , 264 :8892 , 1989
Abstract :
PubMedSearch : Kobayashi_1989_J.Biol.Chem_264_8892
PubMedID: 2722805
Gene_locus related to this paper: ratno-acph

Title : Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction - Kobayashi_1987_J.Biol.Chem_262_11435
Author(s) : Kobayashi K , Smith JA
Ref : Journal of Biological Chemistry , 262 :11435 , 1987
Abstract :
PubMedSearch : Kobayashi_1987_J.Biol.Chem_262_11435
PubMedID: 3305492
Gene_locus related to this paper: ratno-acph