Gly-Pro-pNA

General

Type : Peptide, Pyrrolidine, Carboxamide, p-nitroaniline, pNP, Chromogen

Chemical_Nomenclature : (2S)-1-(2-aminoacetyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide

Canonical SMILES : C1CC(N(C1)C(=O)CN)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]

InChI : InChI=1S\/C13H16N4O4\/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21\/h3-6,11H,1-2,7-8,14H2,(H,15,19)\/t11-\/m0\/s1

InChIKey : NCOCKEVUJUIWRX-NSHDSACASA-N

Other name(s) : GP-pNA, Chromogenic Substrate  ||  Gly-Pro p-nitroanilide hydrochloride  ||  1-(2-aminoacetyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide hydrochloride  ||  G0513_SIGMA  ||  CTK8E9540  ||  AC1OIBUB  ||  SCHEMBL379486  ||  SCHEMBL5087159  ||  ZINC4544878  ||  (2S)-1-(2-aminoacetyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide  ||  1-(2-aminoacetyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide  ||  Gly-Pro-pNA  ||  Gly-Pro-p-nitroaniline  ||  SCHEMBL4372297  ||  BDBM11526


MW : 292.29

Formula : C13H16N4O4

CAS_number : 103213-34-9

PubChem : 7275806,    4297684

UniChem : NCOCKEVUJUIWRX-NSHDSACASA-N

Target

Structures : No structure

Families : DPP4N_Peptidase_S9, Prolylcarboxypeptidase, Lactobacillus_peptidase

References (8)

Title : Elucidating the Role of a Calcium-Binding Loop in an x-Prolyl Aminodipeptidase from Lb. helveticus - Ryder_2023_ACS.Omega_8_35410
Author(s) : Ryder S , Pedigo J , Ojennus DD
Ref : ACS Omega , 8 :35410 , 2023
Abstract :
PubMedSearch : Ryder_2023_ACS.Omega_8_35410
PubMedID: 37779945
Gene_locus related to this paper: lache-pepx

Title : Effect of zinc and calcium ions on the rat kidney membrane-bound form of dipeptidyl peptidase IV - Gomez_2013_J.Biosci_38_461
Author(s) : Gomez H , Chappe M , Valiente PA , Pons T , Chavez Mde L , Charli JL , Pascual I
Ref : J Biosci , 38 :461 , 2013
Abstract :
PubMedSearch : Gomez_2013_J.Biosci_38_461
PubMedID: 23938379

Title : Dipeptidyl peptidase-IV is a potential molecular biomarker in diabetic kidney disease - Sun_2012_Diab.Vasc.Dis.Res_9_301
Author(s) : Sun AL , Deng JT , Guan GJ , Chen SH , Liu YT , Cheng J , Li ZW , Zhuang XH , Sun FD , Deng HP
Ref : Diab Vasc Dis Res , 9 :301 , 2012
Abstract :
PubMedSearch : Sun_2012_Diab.Vasc.Dis.Res_9_301
PubMedID: 22388283

Title : Distribution of dipeptidyl peptidase IV in patients with chronic tonsillitis - Stankovic_2008_Clin.Vaccine.Immunol_15_794
Author(s) : Stankovic M , Vlahovic P , Avramovic V , Todorovic M
Ref : Clin Vaccine Immunol , 15 :794 , 2008
Abstract :
PubMedSearch : Stankovic_2008_Clin.Vaccine.Immunol_15_794
PubMedID: 18385458

Title : Elevated serum dipeptidyl peptidase IV activity in patients with chronic tonsillitis - Vlahovic_2007_Ann.Clin.Biochem_44_70
Author(s) : Vlahovic P , Avramovic V , Stankovic M , Savic S , Todorovic M
Ref : Annals of Clinical Biochemistry , 44 :70 , 2007
Abstract :
PubMedSearch : Vlahovic_2007_Ann.Clin.Biochem_44_70
PubMedID: 17270095

Title : Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78\/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis - Mavropoulos_2005_J.Rheumatol_32_2116
Author(s) : Mavropoulos JC , Cuchacovich M , Llanos C , Aguillon JC , Gatica H , Pizzo SV , Gonzalez-Gronow M
Ref : J Rheumatol , 32 :2116 , 2005
Abstract :
PubMedSearch : Mavropoulos_2005_J.Rheumatol_32_2116
PubMedID: 16265688

Title : Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase - Underwood_1999_J.Biol.Chem_274_34053
Author(s) : Underwood R , Chiravuri M , Lee H , Schmitz T , Kabcenell AK , Yardley K , Huber BT
Ref : Journal of Biological Chemistry , 274 :34053 , 1999
Abstract :
PubMedSearch : Underwood_1999_J.Biol.Chem_274_34053
PubMedID: 10567372
Gene_locus related to this paper: human-DPP7

Title : Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans - Beauvais_1997_Infect.Immun_65_3042
Author(s) : Beauvais A , Monod M , Wyniger J , Debeaupuis JP , Grouzmann E , Brakch N , Svab J , Hovanessian AG , Latge JP
Ref : Infect Immun , 65 :3042 , 1997
Abstract :
PubMedSearch : Beauvais_1997_Infect.Immun_65_3042
PubMedID: 9234752
Gene_locus related to this paper: aspfu-DPP4