Family: Lactobacillus_peptidase

Block: X

Parent Family: Peptidase_S15


Lactococcus X-Pro dipeptidyl-peptidase proteins (X-PDAP) belong to the S15 family of the carboxypeptidase (SC) clan. These proteins, which have similar pecificity to mammalian dipeptidyl-peptidase IV, cleave Xaa-Pro-releasing N-terminal dipeptides. The penultimate residue must be proline. In Lactococcus, the proteins exist as cytoplasmic homodimers. The closest relative is Cocaine_esterase


Interpro : IPR000383 X-Pro dipeptidyl-peptidase-like domain Peptidase_S15

PIRSF : PIRSF009397 X-Pro dipeptidyl-peptidase

Pdoc : No Pdoc

Pfam : PF02129 Peptidase_S15

Prints : No Print

EC Number :


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (2)

Genes Proteins in Lactobacillus_peptidase family (37)

No fragment of genes

Structures in Lactobacillus_peptidase family (2)

Substrates in Lactobacillus_peptidase family (1)

Inhibitors in Lactobacillus_peptidase family (2)

References (2)

Title : Elucidating the Role of a Calcium-Binding Loop in an x-Prolyl Aminodipeptidase from Lb. helveticus - Ryder_2023_ACS.Omega_8_35410
Author(s) : Ryder S , Pedigo J , Ojennus DD
Ref : ACS Omega , 8 :35410 , 2023
PubMedID: 37779945
Gene_locus related to this paper: lache-pepx

Title : The Structural Basis for Catalysis and Specificity of the X-Prolyl Dipeptidyl Aminopeptidase from Lactococcus lactis - Rigolet_2002_Structure.(Camb)_10_1383
Author(s) : Rigolet P , Mechin I , Delage M , Chich J
Ref : Structure (Camb) , 10 :1383 , 2002
PubMedID: 12377124
Gene_locus related to this paper: lacla-pepx