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Carboxamide

compound with the general formula R1C(=O)NR2R3, where R1, R2, and R3 represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein. Building block for many inhibitors of enzymes
Substrate Main targeted enzyme families Type Structure
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
DTNP BCHE Fluorescent Probe Hemicyanine Near-Infrared fluorescent Probe Triazol Carboxamide Xanthene Cyclopropyl HDAC inhibitor
N-benzyl-picolinamide Hormone-sensitive_lipase_like Pyridine Carboxamide
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Rufinamide Carb_B_Chordata Triazol Carboxamide Drug Not AlphaBeta Hydrolase target
Gly-Pro-Leu-beta-NA Tiancimycin-TnmK-Tripeptidase-HIP Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Tribenuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Triazine
Sulfometuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Bensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative
Ethametsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Metsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Thifensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Triazine Thiophen
Chlorimuron-methyl BioH Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Pyrimidine Benzoate Organochlorine
Ethyl-2-(carbamoylsulfamoyl)benzoate BioH Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Benzoate
L-prolinamide Proline_iminopeptidase Carboxamide Pyrrolidine Peptide
Piperazine-2-tert-butylcarboxamide Proline_iminopeptidase Carboxamide Piperazine tert-Butyl
(S)-piperazine-2-carboxamide Proline_iminopeptidase Piperazine Carboxamide
AND-logic-probe-P2 BCHE Phenothiazine Carboxamide Sulfur Compound
Vixotrigine Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Pyrrolidine Carboxamide
Carbamazepine-10,11-epoxide Epoxide_hydrolase Benzazepin Epoxide Carboxamide Azepane
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
Eslicarbazepine-acetate Carb_B_Chordata Arylacetamide_deacetylase Drug Pro-Drug Benzazepin Carbamate Acetate Carboxamide Azepane
Cerulenin Dieckmann_Cyclase Epoxide Carboxamide
Prolyl-2-naphthylamide Carb_B_Chordata PMH_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Pyrazosulfuron Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Chlorimuron Bacterial_esterase Herbicide Sulfonamide Benzenesulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine Benzoate Organochlorine
Chlorimuron-ethyl Carb_B_Bacteria BioH Bacterial_esterase Haloperoxidase Herbicide Benzoate Sulfur Compound Sulfonamide Urea derivative Organochlorine Carboxamide Pyrimidine
DB07813 DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Ala-Pro-AFC Prolylcarboxypeptidase DPP4N_Peptidase_S9 Peptide Coumarin Trifluoro Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Z-Gly-Pro-pNA S9N_PPCE_Peptidase_S9 Benzyloxycarbonyl Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Pro-pNA DPP4N_Peptidase_S9 Prolylcarboxypeptidase Lactobacillus_peptidase Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Lys-Pro-MNA DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Arg-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-Ala-pNA Tiancimycin-TnmK-Tripeptidase-HIP Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Phe-pNA Prolyl_oligopeptidase_S9 DPP4N_Peptidase_S9 Peptide Carboxamide p-nitroaniline pNP Chromogen
BHETA Tannase Terephthalate Phthalate Carboxamide
H-Pro-AMC Proline_iminopeptidase Peptide Coumarin Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Gly-Pro-4MbNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide Naphthalen Naphthylamide
Gly-Pro-AMC DPP4N_Peptidase_S9 Coumarin Peptide Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Naphthol-AS-D-acetate HNLyase_Bact Acetate Naphtyl ester Naphthalen Carboxamide Aromatic ester (two rings)
Niraparib Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Imidazole Piperidine Carboxamide Indazole
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
N-benzyl-picolinamide Hormone-sensitive_lipase_like Pyridine Carboxamide
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Rufinamide Carb_B_Chordata Triazol Carboxamide Drug Not AlphaBeta Hydrolase target
Gly-Pro-Leu-beta-NA Tiancimycin-TnmK-Tripeptidase-HIP Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Tribenuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Triazine
Sulfometuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Bensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative
Ethametsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Metsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Thifensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Triazine Thiophen
Chlorimuron-methyl BioH Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Pyrimidine Benzoate Organochlorine
Ethyl-2-(carbamoylsulfamoyl)benzoate BioH Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Benzoate
L-prolinamide Proline_iminopeptidase Carboxamide Pyrrolidine Peptide
Piperazine-2-tert-butylcarboxamide Proline_iminopeptidase Carboxamide Piperazine tert-Butyl
(S)-piperazine-2-carboxamide Proline_iminopeptidase Piperazine Carboxamide
AND-logic-probe-P2 BCHE Phenothiazine Carboxamide Sulfur Compound
Vixotrigine Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Pyrrolidine Carboxamide
Carbamazepine-10,11-epoxide Epoxide_hydrolase Benzazepin Epoxide Carboxamide Azepane
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
Eslicarbazepine-acetate Carb_B_Chordata Arylacetamide_deacetylase Drug Pro-Drug Benzazepin Carbamate Acetate Carboxamide Azepane
Cerulenin Dieckmann_Cyclase Epoxide Carboxamide
Prolyl-2-naphthylamide Carb_B_Chordata PMH_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Pyrazosulfuron Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Chlorimuron Bacterial_esterase Herbicide Sulfonamide Benzenesulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine Benzoate Organochlorine
Chlorimuron-ethyl Carb_B_Bacteria BioH Bacterial_esterase Haloperoxidase Herbicide Benzoate Sulfur Compound Sulfonamide Urea derivative Organochlorine Carboxamide Pyrimidine
DB07813 DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Ala-Pro-AFC Prolylcarboxypeptidase DPP4N_Peptidase_S9 Peptide Coumarin Trifluoro Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Z-Gly-Pro-pNA S9N_PPCE_Peptidase_S9 Benzyloxycarbonyl Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Pro-pNA DPP4N_Peptidase_S9 Prolylcarboxypeptidase Lactobacillus_peptidase Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Lys-Pro-MNA DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Arg-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-Ala-pNA Tiancimycin-TnmK-Tripeptidase-HIP Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Phe-pNA Prolyl_oligopeptidase_S9 DPP4N_Peptidase_S9 Peptide Carboxamide p-nitroaniline pNP Chromogen
BHETA Tannase Terephthalate Phthalate Carboxamide
H-Pro-AMC Proline_iminopeptidase Peptide Coumarin Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Gly-Pro-4MbNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide Naphthalen Naphthylamide
Gly-Pro-AMC DPP4N_Peptidase_S9 Coumarin Peptide Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Naphthol-AS-D-acetate HNLyase_Bact Acetate Naphtyl ester Naphthalen Carboxamide Aromatic ester (two rings)
Niraparib Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Imidazole Piperidine Carboxamide Indazole
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide Sulfur Compound Thiazole
N-benzyl-picolinamide Hormone-sensitive_lipase_like Pyridine Carboxamide
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Rufinamide Carb_B_Chordata Triazol Carboxamide Drug Not AlphaBeta Hydrolase target
Gly-Pro-Leu-beta-NA Tiancimycin-TnmK-Tripeptidase-HIP Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Tribenuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Triazine
Sulfometuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Bensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative
Ethametsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Metsulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Triazine
Thifensulfuron-methyl Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Triazine Thiophen
Chlorimuron-methyl BioH Herbicide Sulfonamide Sulfur Compound Carboxamide Benzenesulfonamide Urea derivative Pyrimidine Benzoate Organochlorine
Ethyl-2-(carbamoylsulfamoyl)benzoate BioH Herbicide Sulfonamide Sulfur Compound Benzenesulfonamide Carboxamide Urea derivative Benzoate
L-prolinamide Proline_iminopeptidase Carboxamide Pyrrolidine Peptide
Piperazine-2-tert-butylcarboxamide Proline_iminopeptidase Carboxamide Piperazine tert-Butyl
(S)-piperazine-2-carboxamide Proline_iminopeptidase Piperazine Carboxamide
AND-logic-probe-P2 BCHE Phenothiazine Carboxamide Sulfur Compound
Vixotrigine Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Pyrrolidine Carboxamide
Carbamazepine-10,11-epoxide Epoxide_hydrolase Benzazepin Epoxide Carboxamide Azepane
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
Eslicarbazepine-acetate Carb_B_Chordata Arylacetamide_deacetylase Drug Pro-Drug Benzazepin Carbamate Acetate Carboxamide Azepane
Cerulenin Dieckmann_Cyclase Epoxide Carboxamide
Prolyl-2-naphthylamide Carb_B_Chordata PMH_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Pyrazosulfuron Bacterial_esterase Herbicide Sulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine
Chlorimuron Bacterial_esterase Herbicide Sulfonamide Benzenesulfonamide Sulfur Compound Carboxamide Urea derivative Pyrimidine Benzoate Organochlorine
Chlorimuron-ethyl Carb_B_Bacteria BioH Bacterial_esterase Haloperoxidase Herbicide Benzoate Sulfur Compound Sulfonamide Urea derivative Organochlorine Carboxamide Pyrimidine
DB07813 DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Ala-Pro-AFC Prolylcarboxypeptidase DPP4N_Peptidase_S9 Peptide Coumarin Trifluoro Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Z-Gly-Pro-pNA S9N_PPCE_Peptidase_S9 Benzyloxycarbonyl Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Pro-pNA DPP4N_Peptidase_S9 Prolylcarboxypeptidase Lactobacillus_peptidase Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Lys-Pro-MNA DPP4N_Peptidase_S9 Naphthylamide Peptide Pyrrolidine Carboxamide Naphthalen
Arg-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-Ala-pNA Tiancimycin-TnmK-Tripeptidase-HIP Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Ala-Pro-pNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide p-nitroaniline pNP Chromogen
Gly-Phe-pNA Prolyl_oligopeptidase_S9 DPP4N_Peptidase_S9 Peptide Carboxamide p-nitroaniline pNP Chromogen
BHETA Tannase Terephthalate Phthalate Carboxamide
H-Pro-AMC Proline_iminopeptidase Peptide Coumarin Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Gly-Pro-4MbNA DPP4N_Peptidase_S9 Peptide Pyrrolidine Carboxamide Naphthalen Naphthylamide
Gly-Pro-AMC DPP4N_Peptidase_S9 Coumarin Peptide Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
Naphthol-AS-D-acetate HNLyase_Bact Acetate Naphtyl ester Naphthalen Carboxamide Aromatic ester (two rings)