Josamycin
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate
Canonical SMILES : C[C@@H]1C\/C=C\/C=C\/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)OC(=O)C)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)O
InChI : InChI=1S\/C42H69NO15\/c1-23(2)19-32(47)56-40-27(6)53-34(22-42(40,8)50)57-37-26(5)54-41(36(49)35(37)43(9)10)58-38-29(17-18-44)20-24(3)30(46)16-14-12-13-15-25(4)52-33(48)21-31(39(38)51-11)55-28(7)45\/h12-14,16,18,23-27,29-31,34-41,46,49-50H,15,17,19-22H2,1-11H3\/b13-12+,16-14+\/t24-,25-,26-,27+,29+,30+,31-,34+,35-,36-,37-,38+,39+,40+,41+,42-\/m1\/s1
InChIKey : XJSFLOJWULLJQS-NGVXBBESSA-N
Other name(s) : Leucomycin A3 || Turimycin A5 || Kitasamycin A3 || Josamycine || 16846-24-5 || Josamicina || Antibiotic yl-704 A3
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (3)
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |