Midecamycin
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-[(2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-propanoyloxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
Canonical SMILES : CCC(=O)O[C@@H]1CC(=O)O[C@@H](C\/C=C\/C=C\/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]1OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC)(C)O)N(C)C)O)CC=O)C)O)C
InChI : InChI=1S\/C41H67NO15\/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2\/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3\/b14-13+,17-15+\/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-\/m1\/s1
InChIKey : DMUAPQTXSSNEDD-QALJCMCCSA-N
Other name(s) : Rubimycin || Espinomycin A || Platenomycin B1 || Turimycin P3 || Medemycin || Macropen || RefChem:818844 || SCHEMBL141581 || CHEMBL444963 || CHEBI:31845 || DB13456
MW : 814
Formula : C41H67NO15
CAS_number : 35457-80-8
PubChem : 5282169
UniChem : DMUAPQTXSSNEDD-QALJCMCCSA-N
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (3)
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |