Oxybuprocaine
Local anaesthetic (ester 'caine') used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
General
Type : Drug, Local anesthetic, Not AlphaBeta Hydrolase target
Chemical_Nomenclature : 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate
Canonical SMILES : CCCCOC1=C(C=CC(=C1)C(=O)OCCN(CC)CC)N
InChI : InChI=1S\/C17H28N2O3\/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3\/h8-9,13H,4-7,10-12,18H2,1-3H3
InChIKey : CMHHMUWAYWTMGS-UHFFFAOYSA-N
Other name(s) : Benoxinate || Oxybucaine || Oxyriprocaine
MW : 308.4
Formula : C17H28N2O3
CAS_number : 99-43-4
PubChem : 4633
UniChem : CMHHMUWAYWTMGS-UHFFFAOYSA-N
Target
Structures : No structure
Families : BCHE
References (6)
| Title : Interindividual differences of corneal sensitivity. Genetic aspects - Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| Author(s) : Draeger J , Schloot W , Wirt H |
| Ref : Ophthalmic Paediatr Genet , 6 :291 , 1985 |
| Abstract : |
| PubMedSearch : Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| PubMedID: 4069587 |
| Title : Interindividual differences of corneal sensitivity. Genetic aspects - Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| Author(s) : Draeger J , Schloot W , Wirt H |
| Ref : Ophthalmic Paediatr Genet , 6 :291 , 1985 |
| Abstract : |
| PubMedSearch : Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| PubMedID: 4069587 |
| Title : Interindividual differences of corneal sensitivity. Genetic aspects - Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| Author(s) : Draeger J , Schloot W , Wirt H |
| Ref : Ophthalmic Paediatr Genet , 6 :291 , 1985 |
| Abstract : |
| PubMedSearch : Draeger_1985_Ophthalmic.Paediatr.Genet_6_291 |
| PubMedID: 4069587 |
| Title : Studies on the metabolism of benoxinate by human pseudocholinesterase - Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| Author(s) : Dubbels R , Schloot W |
| Ref : Metab Pediatr Syst Ophthalmol , 7 :37 , 1983 |
| Abstract : |
| PubMedSearch : Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| PubMedID: 6621359 |
| Title : Studies on the metabolism of benoxinate by human pseudocholinesterase - Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| Author(s) : Dubbels R , Schloot W |
| Ref : Metab Pediatr Syst Ophthalmol , 7 :37 , 1983 |
| Abstract : |
| PubMedSearch : Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| PubMedID: 6621359 |
| Title : Studies on the metabolism of benoxinate by human pseudocholinesterase - Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| Author(s) : Dubbels R , Schloot W |
| Ref : Metab Pediatr Syst Ophthalmol , 7 :37 , 1983 |
| Abstract : |
| PubMedSearch : Dubbels_1983_Metab.Pediatr.Syst.Ophthalmol_7_37 |
| PubMedID: 6621359 |