Local anesthetic

A local anesthetic (LA) is a medication that causes absence of pain sensation. In the context of surgery, a local anesthetic creates an absence of pain in a specific location of the body without a loss of consciousness, as opposed to a general anesthetic. When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) also can be achieved.
Substrate Main targeted enzyme families Type Structure
Prilocaine Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Isobucaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Meprylcaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Oxybuprocaine BCHE Drug Local anesthetic Not AlphaBeta Hydrolase target
Procaine BCHE Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Organochlorine
Lidocaine Carboxylesterase Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Prilocaine Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Isobucaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Meprylcaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Oxybuprocaine BCHE Drug Local anesthetic Not AlphaBeta Hydrolase target
Procaine BCHE Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Organochlorine
Lidocaine Carboxylesterase Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Prilocaine Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Isobucaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Meprylcaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Oxybuprocaine BCHE Drug Local anesthetic Not AlphaBeta Hydrolase target
Procaine BCHE Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Tetracaine BCHE Local anesthetic Organochlorine
Lidocaine Carboxylesterase Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target