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  3. Not AlphaBeta Hydrolase target

Not AlphaBeta Hydrolase target

Substrates or inhibitors which are not primarily found or designed to be ligand of any alpha\/beta hydrolases. Some Alpha\/beta hydrolases can be considered as off targets of these compounds
Substrate Main targeted enzyme families Type Structure
Capsaicin Canar_LipB Fatty acid ester Natural Not AlphaBeta Hydrolase target
Anandamide Acyl-Glycerol Natural Arachidonate Not AlphaBeta Hydrolase target
Epalrestat-RM-13 Not AlphaBeta Hydrolase target Pro-Drug Drug Fluorescent Probe Coumarin Chromen Thiazolidine Sulfur Compound
Epalrestat-RM-28 Not AlphaBeta Hydrolase target Pro-Drug Drug Fluorescent Probe Coumarin Chromen
KGP-25 Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Multitarget
Homocysteine-thiolactone Valacyclovir-hydrolase Carb_B_Chordata BCHE Natural Sulfur Compound Not AlphaBeta Hydrolase target Thiophen
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine
Ramipril Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Peptide
NT-0796 Carboxylesterase Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Indacen Pyrimidine
Candesartan-cilexetil Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyrrolidine Angiotensin-receptor blocker Benzimidazole
Fosinopril Plasmodium_subtelomeric_PST-A Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor Organophosphate
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
2,4-D-Butyl-ester Lipase_2 Herbicide Not AlphaBeta Hydrolase target
Cypermethrin Carb_B_Arthropoda LYsophospholipase_carboxylesterase Carb_B_Chordata 6_AlphaBeta_hydrolase Pyrethroid Insecticide Phenoxyphenyl Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Cypermethrine-analog-fluo-CpdII Carb_B_Arthropoda Pyrethroid Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Fenvalerate-analog-fluo-CpdII Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide
Cypermethrine-analog-acid-CpdI Carb_B_Arthropoda Carb_B_Chordata Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Fenvalerate-analog-acid-CpdI Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide
2,4-D-Methyl Plant_carboxylesterase Herbicide Not AlphaBeta Hydrolase target
Rufinamide Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Carboxamide Triazol
Dimethyl-fumarate Carb_B_Chordata Drug Pro-Drug Not AlphaBeta Hydrolase target
Beclomethasone-dipropionate Arylacetamide_deacetylase Drug Pro-Drug Not AlphaBeta Hydrolase target Steroid Propionate Phenanthrene
Esmolol Carb_B_Chordata LYsophospholipase_carboxylesterase Not AlphaBeta Hydrolase target Drug Propionate
S-bromobenzylglutathione-dicyclopentyl-ester Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Sulfur Compound Peptide
Phenytoin Not AlphaBeta Hydrolase target
Diltiazem Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Calcium Channel Antagonist Azepane Benzothiazepine
ADP-ribose Plant_lipase_EDS1-like Aminopurin Not AlphaBeta Hydrolase target Purine Drug Ribose
Remimazolam Carb_B_Chordata Benzodiazepin Not AlphaBeta Hydrolase target Drug Propionate Azepane
MGS0274 Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug
Mirabegron BCHE Drug Not AlphaBeta Hydrolase target Adrenergic-Receptor-ligand Thiazol Sulfur Compound
Amplex-red Carb_B_Chordata Phenoxazin Derivative of Resorufin Not AlphaBeta Hydrolase target Fluorescent Probe
RedGreen-BODIPY-PC-A2 Fluorescent Probe BODIPY-derivative Choline ester Boron compound Not AlphaBeta Hydrolase target Trimethylammonium Phospholipid
Ethyl-Zaltoprofen Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Not AlphaBeta Hydrolase target Drug Pro-Drug Propionate Alkyl ester
Ethyl-Carprofen Hormone-sensitive_lipase_like Not AlphaBeta Hydrolase target Drug Pro-Drug Carbazol Propionate Alkyl ester
Ethyl-Flurbiprofen Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Canar_LipB Not AlphaBeta Hydrolase target Drug Pro-Drug Propionate Alkyl ester
Imidapril Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Imidazole
Indiplon Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Sulfur Compound Pyrimidine Pyrazole Thiophen
Rifapentine Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperazine Antibiotic
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperidine Antibiotic
Baloxavir-marboxil Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Sulfur Compound
Abiraterone-acetate Arylacetamide_deacetylase Pro-Drug Drug Pyridine Not AlphaBeta Hydrolase target Phenanthrene
Ketoconazole Arylacetamide_deacetylase Pro-Drug Drug Not AlphaBeta Hydrolase target Piperazine Imidazole Dioxolane
Flupirtine Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Carbamate
Acebutolol Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target
Mycophenolate-mofetil Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Morpholine Benzofuran
Nintedanib Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Piperazine
Vixotrigine Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Pyrrolidine Carboxamide
Clofibrate Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Propionate
Bemnifosbuvir Carboxypeptidase_S10 Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Propionate Purine
Remdesivir Carb_B_Chordata Carboxypeptidase_S10 Pro-Drug Drug Not AlphaBeta Hydrolase target Propionate Triazine
Molnupiravir Carb_B_Chordata BCHE Pro-Drug Drug Not AlphaBeta Hydrolase target Propionate Nucleoside
AZD1979 Epoxide_hydrolase Not AlphaBeta Hydrolase target Azaspiro Oxadiazol Azetidin
Rifampicin Arylacetamide_deacetylase Drug Not AlphaBeta Hydrolase target Acetate Natural Antibiotic
Prasugrel Carb_B_Chordata Arylacetamide_deacetylase Drug Not AlphaBeta Hydrolase target Acetate Cyclopropyl Antiplatlet
Olmesartan-medoxomil CMBL Not AlphaBeta Hydrolase target Tetrazol
N-acetylserotonin Arylacetamide_deacetylase Derivative of Tryptamine Indole Not AlphaBeta Hydrolase target Natural
Trandolapril Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Probenecid-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronide
Mycophenolic-acid-acyl-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronoyl Benzofuran Glucuronide
Simvastatin Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Naphthalen
Cyflumetofen Cholinesterase-like Acaricide Cyanide Propionate Not AlphaBeta Hydrolase target
Selexipag Carb_B_Chordata Sulfonyl Sulfur Compound Not AlphaBeta Hydrolase target Pro-Drug Drug
Ciclesonide Carb_B_Chordata BCHE Not AlphaBeta Hydrolase target Pro-Drug Butyrate Drug
Clevidipine Not AlphaBeta Hydrolase target Pro-Drug Butyrate Drug
Iomazenil Carb_B_Chordata Benzodiazepin Not AlphaBeta Hydrolase target Drug Azepane
trans-Bifenthrin HNLyase_Bact Carb_B_Arthropoda Pyrethroid Insecticide Trifluoro Not AlphaBeta Hydrolase target Carbamate Cyclopropyl
Fenpropathrin Carb_B_Arthropoda Cholinesterase-like Pyrethroid Insecticide Acaricide Cyanide Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
Vicagrel Arylacetamide_deacetylase Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pyridine Acetate Antiplatlet
2-oxo-clopidogrel Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyridine Acetate Antiplatlet
Benzoylecgonine BCHE Cocaine_esterase Drug Not AlphaBeta Hydrolase target Alkaloid Azabicyclo
Dipivefrin Carb_B_Chordata ACHE BCHE Drug Not AlphaBeta Hydrolase target Pro-Drug Propionate
Homatropine Carb_B_Chordata A85-Mycolyl-transferase Not AlphaBeta Hydrolase target Drug Azabicyclo
W22-methyl-ester Bacterial_esterase Canar_LipB Benzodiazepin Not AlphaBeta Hydrolase target Drug Pro-Drug Azepane
Enalapril Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Quinapril Carb_B_Chordata Isoquinoline Not AlphaBeta Hydrolase target Drug Pro-Drug Angiotensin-converting enzyme inhibitor
Sacubitril Carb_B_Chordata Pro-Drug Not AlphaBeta Hydrolase target Drug Oxobutanoate
Dabigatran-etexilate Carb_B_Chordata Pro-Drug Not AlphaBeta Hydrolase target Drug Pyridine Propionate Benzimidazole
Clopidogrel Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pyridine Antiplatlet
Temocapril Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Angiotensin-converting enzyme inhibitor Azepane Thiophen
Sivelestat Carb_B_Chordata Peptide Drug Not AlphaBeta Hydrolase target Pro-Drug Sulfur Compound Sulfonamide Benzenesulfonamide
Camostat Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Pro-Drug
Dilazep Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Pro-Drug Diazepane
Delapril Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Pro-Drug Peptide
Benazepril Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Pro-Drug Benzazepin Azepane
Oxybutinin Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Pro-Drug Muscarinic antagonist Neuromuscular Nondepolarizing Agents
Methylphenidate Carb_B_Chordata Piperidine Not AlphaBeta Hydrolase target Drug
PAF PAF-Acetylhydrolase LYsophospholipase_carboxylesterase Natural Trimethylammonium Water-insoluble medium and long chain ester Choline ester Not AlphaBeta Hydrolase target Phosphatidylcholine
Oseltamivir Carb_B_Chordata BCHE Pro-Drug Drug Not AlphaBeta Hydrolase target
DTS-108 Carboxylesterase Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Peptide
Valgancyclovir Valacyclovir-hydrolase Purine Drug Not AlphaBeta Hydrolase target
Valacyclovir Valacyclovir-hydrolase Purine Drug Not AlphaBeta Hydrolase target Nucleoside
Remifentanil Carboxylesterase Carb_B_Chordata Drug Not AlphaBeta Hydrolase target Opioid analgesic
Isobucaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Meprylcaine BCHE Local anesthetic Not AlphaBeta Hydrolase target
Atropine BCHE AlphaBeta_hydrolase Not AlphaBeta Hydrolase target Muscarinic antagonist Drug Alkaloid Natural Azabicyclo Propionate
Carbachol ACHE Drug Not AlphaBeta Hydrolase target Carbamate Trimethylammonium Choline ester Analogue of substrate Muscarinic agonist Nicotinic agonist
NPC Carb_B_Bacteria Carbamate Drug Derivative of Irinotecan Not AlphaBeta Hydrolase target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not AlphaBeta Hydrolase target
Mivacurium BCHE Neuromuscular Nondepolarizing Agents Drug Isoquinoline Bisquaternary Not AlphaBeta Hydrolase target
Permethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria Pyrethroid Insecticide Drug Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
Oxybuprocaine BCHE Drug Local anesthetic Not AlphaBeta Hydrolase target
Procaine BCHE Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target
Lidocaine Carboxylesterase Carb_B_Chordata Local anesthetic Drug Not AlphaBeta Hydrolase target