P(3HB-co-LA)
Copolymer of Polyhydroxybutyrate (PHB) and Lactic acid (LA). Polyhydroxybutyrate (PHB) is a polyhydroxyalkanoate (PHA) is produced by bacteria ( Ralstonia eutrophus, Methylobacterium rhodesianum or Bacillus megaterium) when nutrients are limited. The poly-3-hydroxybutyrate (P3HB)is the most common type, but other polymers are also produced. They are used as source of bio-derived and biodegradable plastics.
General
Type : Polyhydroxyalkanoate, Natural, Polymer
Chemical_Nomenclature :
Canonical SMILES :
InChI :
InChIKey :
Other name(s) : Poly(3-hydroxybutyrate-co-lactate)
MW :
Formula :
CAS_number :
PubChem :
UniChem :
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Target
Structures : No structure
Families : No family
References (20)
| Title : Engineering of fast-growing Vibrio natriegens for biosynthesis of poly(3-hydroxybutyrate-co-lactate) - Sun_2024_Bioresour.Bioprocess_11_86 |
| Author(s) : Sun X , Shang Y , Zhang B , Guo P , Luo Y , Wu H |
| Ref : Bioresour Bioprocess , 11 :86 , 2024 |
| Abstract : |
| PubMedSearch : Sun_2024_Bioresour.Bioprocess_11_86 |
| PubMedID: 39249183 |
| Title : Enhancement of lactate fraction in poly(lactate-co-3-hydroxybutyrate) biosynthesized by metabolically engineered E. coli - Zhang_2024_Bioresour.Bioprocess_11_88 |
| Author(s) : Zhang B , Guo P , Sun X , Shang Y , Luo Y , Wu H |
| Ref : Bioresour Bioprocess , 11 :88 , 2024 |
| Abstract : |
| PubMedSearch : Zhang_2024_Bioresour.Bioprocess_11_88 |
| PubMedID: 39297980 |
| Title : Cell-growth phase-dependent promoter replacement approach for improved poly(lactate-co-3-hydroxybutyrate) production in Escherichia coli - Nagao_2023_Microb.Cell.Fact_22_131 |
| Author(s) : Nagao Y , Koh S , Taguchi S , Shimada T |
| Ref : Microb Cell Fact , 22 :131 , 2023 |
| Abstract : |
| PubMedSearch : Nagao_2023_Microb.Cell.Fact_22_131 |
| PubMedID: 37468909 |
| Title : Recent advances in the microbial synthesis of lactate-based copolymer - Guo_2021_Bioresour.Bioprocess_8_106 |
| Author(s) : Guo P , Luo Y , Wu J , Wu H |
| Ref : Bioresour Bioprocess , 8 :106 , 2021 |
| Abstract : |
| PubMedSearch : Guo_2021_Bioresour.Bioprocess_8_106 |
| PubMedID: 38650297 |
| Title : Efficient poly(3-hydroxybutyrate-co-lactate) production from corn stover hydrolysate by metabolically engineered Escherichia coli - Wu_2021_Bioresour.Technol_341_125873 |
| Author(s) : Wu J , Wei X , Guo P , He A , Xu J , Jin M , Zhang Y , Wu H |
| Ref : Bioresour Technol , 341 :125873 , 2021 |
| Abstract : |
| PubMedSearch : Wu_2021_Bioresour.Technol_341_125873 |
| PubMedID: 34523584 |
| Title : In Vitro Analysis of d-Lactyl-CoA-Polymerizing Polyhydroxyalkanoate Synthase in Polylactate and Poly(lactate- co-3-hydroxybutyrate) Syntheses - Matsumoto_2018_Biomacromolecules_19_2889 |
| Author(s) : Matsumoto K , Iijima M , Hori C , Utsunomia C , Ooi T , Taguchi S |
| Ref : Biomacromolecules , 19 :2889 , 2018 |
| Abstract : |
| PubMedSearch : Matsumoto_2018_Biomacromolecules_19_2889 |
| PubMedID: 29667817 |
| Title : Genome-engineered Sinorhizobium meliloti for the production of poly(lactic-co-3-hydroxybutyric) acid copolymer - Tran_2016_Can.J.Microbiol_62_130 |
| Author(s) : Tran TT , Charles TC |
| Ref : Can J Microbiol , 62 :130 , 2016 |
| Abstract : |
| PubMedSearch : Tran_2016_Can.J.Microbiol_62_130 |
| PubMedID: 26639519 |
| Title : Molecular weight-dependent degradation of D-lactate-containing polyesters by polyhydroxyalkanoate depolymerases from Variovorax sp. C34 and Alcaligenes faecalis T1 - Sun_2015_Appl.Microbiol.Biotechnol_99_9555 |
| Author(s) : Sun J , Matsumoto K , Tabata Y , Kadoya R , Ooi T , Abe H , Taguchi S |
| Ref : Applied Microbiology & Biotechnology , 99 :9555 , 2015 |
| Abstract : |
| PubMedSearch : Sun_2015_Appl.Microbiol.Biotechnol_99_9555 |
| PubMedID: 26109003 |
| Title : Enhanced production of polyhydroxyalkanoates (PHAs) from beechwood xylan by recombinant Escherichia coli - Salamanca-Cardona_2014_Appl.Microbiol.Biotechnol_98_831 |
| Author(s) : Salamanca-Cardona L , Ashe CS , Stipanovic AJ , Nomura CT |
| Ref : Applied Microbiology & Biotechnology , 98 :831 , 2014 |
| Abstract : |
| PubMedSearch : Salamanca-Cardona_2014_Appl.Microbiol.Biotechnol_98_831 |
| PubMedID: 24287934 |
| Title : Metabolic engineering of Ralstonia eutropha for the biosynthesis of 2-hydroxyacid-containing polyhydroxyalkanoates - Park_2013_Metab.Eng_20_20 |
| Author(s) : Park SJ , Jang YA , Lee H , Park AR , Yang JE , Shin J , Oh YH , Song BK , Jegal J , Lee SH , Lee SY |
| Ref : Metab Eng , 20 :20 , 2013 |
| Abstract : |
| PubMedSearch : Park_2013_Metab.Eng_20_20 |
| PubMedID: 23973656 |
| Title : Effectiveness of xylose utilization for high yield production of lactate-enriched P(lactate-co-3-hydroxybutyrate) using a lactate-overproducing strain of Escherichia coli and an evolved lactate-polymerizing enzyme - Nduko_2013_Metab.Eng_15_159 |
| Author(s) : Nduko JM , Matsumoto K , Ooi T , Taguchi S |
| Ref : Metab Eng , 15 :159 , 2013 |
| Abstract : |
| PubMedSearch : Nduko_2013_Metab.Eng_15_159 |
| PubMedID: 23202750 |
| Title : Engineering of class I lactate-polymerizing polyhydroxyalkanoate synthases from Ralstonia eutropha that synthesize lactate-based polyester with a block nature - Ochi_2013_Appl.Microbiol.Biotechnol_97_3441 |
| Author(s) : Ochi A , Matsumoto K , Ooba T , Sakai K , Tsuge T , Taguchi S |
| Ref : Applied Microbiology & Biotechnology , 97 :3441 , 2013 |
| Abstract : |
| PubMedSearch : Ochi_2013_Appl.Microbiol.Biotechnol_97_3441 |
| PubMedID: 22801709 |
| Title : Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production - Song_2012_Appl.Microbiol.Biotechnol_93_1917 |
| Author(s) : Song Y , Matsumoto K , Yamada M , Gohda A , Brigham CJ , Sinskey AJ , Taguchi S |
| Ref : Applied Microbiology & Biotechnology , 93 :1917 , 2012 |
| Abstract : |
| PubMedSearch : Song_2012_Appl.Microbiol.Biotechnol_93_1917 |
| PubMedID: 22127753 |
| Title : In vitro synthesis of polyhydroxyalkanoate (PHA) incorporating lactate (LA) with a block sequence by using a newly engineered thermostable PHA synthase from Pseudomonas sp. SG4502 with acquired LA-polymerizing activity - Tajima_2012_Appl.Microbiol.Biotechnol_94_365 |
| Author(s) : Tajima K , Han X , Satoh Y , Ishii A , Araki Y , Munekata M , Taguchi S |
| Ref : Applied Microbiology & Biotechnology , 94 :365 , 2012 |
| Abstract : |
| PubMedSearch : Tajima_2012_Appl.Microbiol.Biotechnol_94_365 |
| PubMedID: 22249718 |
| Title : Efficient production of polylactic acid and its copolymers by metabolically engineered Escherichia coli - Jung_2011_J.Biotechnol_151_94 |
| Author(s) : Jung YK , Lee SY |
| Ref : J Biotechnol , 151 :94 , 2011 |
| Abstract : |
| PubMedSearch : Jung_2011_J.Biotechnol_151_94 |
| PubMedID: 21111011 |
| Title : Lactate fraction dependent mechanical properties of semitransparent poly(lactate-co-3-hydroxybutyrate)s produced by control of lactyl-CoA monomer fluxes in recombinant Escherichia coli - Yamada_2011_J.Biotechnol_154_255 |
| Author(s) : Yamada M , Matsumoto K , Uramoto S , Motohashi R , Abe H , Taguchi S |
| Ref : J Biotechnol , 154 :255 , 2011 |
| Abstract : |
| PubMedSearch : Yamada_2011_J.Biotechnol_154_255 |
| PubMedID: 21640144 |
| Title : Tailor-made type II Pseudomonas PHA synthases and their use for the biosynthesis of polylactic acid and its copolymer in recombinant Escherichia coli - Yang_2011_Appl.Microbiol.Biotechnol_90_603 |
| Author(s) : Yang TH , Jung YK , Kang HO , Kim TW , Park SJ , Lee SY |
| Ref : Applied Microbiology & Biotechnology , 90 :603 , 2011 |
| Abstract : |
| PubMedSearch : Yang_2011_Appl.Microbiol.Biotechnol_90_603 |
| PubMedID: 21221571 |
| Gene_locus related to this paper: psech-PHAC1 |
| Title : Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers - Jung_2010_Biotechnol.Bioeng_105_161 |
| Author(s) : Jung YK , Kim TY , Park SJ , Lee SY |
| Ref : Biotechnol Bioeng , 105 :161 , 2010 |
| Abstract : |
| PubMedSearch : Jung_2010_Biotechnol.Bioeng_105_161 |
| PubMedID: 19937727 |
| Title : Adjustable mutations in lactate (LA)-polymerizing enzyme for the microbial production of LA-based polyesters with tailor-made monomer composition - Yamada_2010_Biomacromolecules_11_815 |
| Author(s) : Yamada M , Matsumoto K , Shimizu K , Uramoto S , Nakai T , Shozui F , Taguchi S |
| Ref : Biomacromolecules , 11 :815 , 2010 |
| Abstract : |
| PubMedSearch : Yamada_2010_Biomacromolecules_11_815 |
| PubMedID: 20166718 |
| Title : A microbial factory for lactate-based polyesters using a lactate-polymerizing enzyme - Taguchi_2008_Proc.Natl.Acad.Sci.U.S.A_105_17323 |
| Author(s) : Taguchi S , Yamada M , Matsumoto K , Tajima K , Satoh Y , Munekata M , Ohno K , Kohda K , Shimamura T , Kambe H , Obata S |
| Ref : Proc Natl Acad Sci U S A , 105 :17323 , 2008 |
| Abstract : |
| PubMedSearch : Taguchi_2008_Proc.Natl.Acad.Sci.U.S.A_105_17323 |
| PubMedID: 18978031 |