Phospho-Ibuprofen

General

Type : phospho-NSAID, Drug, Pro-Drug

Chemical_Nomenclature : 2-(4-isobutylphenyl)propionic acid 4-(diethoxyphosphoryloxy)butyl ester

Canonical SMILES : CC(C)CC1=CC=C(C=C1)C(C)(C(=O)O)P(=O)=O

InChI : InChI=1S\/C13H17O4P\/c1-9(2)8-10-4-6-11(7-5-10)13(3,12(14)15)18(16)17\/h4-7,9H,8H2,1-3H3,(H,14,15)

InChIKey : ZXIUZHKMKUFJIG-UHFFFAOYSA-N

Other name(s) : MDC 917  ||  MDC-917  ||  MDC917


MW : .24

Formula : C13H17O4P

CAS_number :

PubChem : 129846570

UniChem : ZXIUZHKMKUFJIG-UHFFFAOYSA-N

Target

Families : Carb_B_Chordata

References (1)

Title : Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity - Wong_2012_J.Pharmacol.Exp.Ther_340_422
Author(s) : Wong CC , Cheng KW , Xie G , Zhou D , Zhu CH , Constantinides PP , Rigas B
Ref : Journal of Pharmacology & Experimental Therapeutics , 340 :422 , 2012
Abstract :
PubMedSearch : Wong_2012_J.Pharmacol.Exp.Ther_340_422
PubMedID: 22085648