Tetracaine

Local anesthetic, substrate as well as inhibitor || Local anesthetic, substrate as well as inhibitor, C15H24N2O2,[94-24-6],264.3

General

Type : Local anesthetic

Chemical_Nomenclature : 4-(Butylamino)benzoicacid 2-(dimethylamino)ehtyl ester

Canonical SMILES : CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C

InChI : InChI=1S\/C15H24N2O2\/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3\/h6-9,16H,4-5,10-12H2,1-3H3

InChIKey : GKCBAIGFKIBETG-UHFFFAOYSA-N

Other name(s) : Amethocaine  ||  Uromucaesthin  ||  Contralgin  ||  Fissucain  ||  Intercain  ||  Laudocaine  ||  Medicaine  ||  Meethobalm  ||  Metraspray  ||  Cetacaine  ||  Pontocain


MW : 300.83

Formula : C15H25ClN2O2

CAS_number : 136-47-0

PubChem : 5411

UniChem : GKCBAIGFKIBETG-UHFFFAOYSA-N

Wikipedia : Tetracaine

Target

Structures : No structure

Families : BCHE

References (4)

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract :
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies - Valentino_1981_Biochem.Pharmacol_30_1643
Author(s) : Valentino RJ , Lockridge O , Eckerson HW , La Du BN
Ref : Biochemical Pharmacology , 30 :1643 , 1981
Abstract :
PubMedSearch : Valentino_1981_Biochem.Pharmacol_30_1643
PubMedID: 7271851

Title : Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide - Whittaker_1981_Hum.Hered_31_242
Author(s) : Whittaker M , Britten JJ
Ref : Hum Hered , 31 :242 , 1981
Abstract :
PubMedSearch : Whittaker_1981_Hum.Hered_31_242
PubMedID: 7287015

Title : The activity of various esterase inhibitors towards atypical human serum cholinesterase -
Author(s) : Kalow W , Davies R0
Ref : Biochemical Pharmacology , 1 :183 , 1958
PubMedID: