Tiancimycin-H
anthraquinone fused enediyne biosynthesis compound containing an unprecedented cryptic C16 aldehyde group
General
Type : Natural, Antibiotic, Polyketide
Chemical_Nomenclature :
Canonical SMILES : C1=CC=C3C(=C1)C(C2=C(C=CC(=C2C3=O)O)NC4C#CC=CC#CC5C(C4=C(C=C5OC)C)C=O)=O
InChI : InChI=1S\/C30H21NO5\/c1-17-15-25(36-2)18-9-5-3-4-6-12-22(26(17)21(18)16-32)31-23-13-14-24(33)28-27(23)29(34)19-10-7-8-11-20(19)30(28)35\/h3-4,7-8,10-11,13-16,18,21-22,31,33H,1-2H3\/b4-3-
InChIKey : JYCGJRIRIPRYLD-ARJAWSKDSA-N
Other name(s) :
Target
Structures : 8E19
Families : Tiancimycin-TnmK-Tripeptidase-HIP
References (1)
| Title : Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis - Gui_2022_J.Am.Chem.Soc__ |
| Author(s) : Gui C , Kalkreuter E , Liu YC , Adhikari A , Teijaro CN , Yang D , Chang C , Shen B |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : |
| PubMedSearch : Gui_2022_J.Am.Chem.Soc__ |
| PubMedID: 36279548 |
| Gene_locus related to this paper: strsp-TnmK1 |