Z-Phe-Arg-AMC

General

Type : Benzyloxycarbonyl || Peptide || 7-amido-4-methylcoumarin || Coumarin

Chemical_Nomenclature : benzyl N-[1-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate

Canonical SMILES : CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4

InChI : InChI=1S\/C33H36N6O6\/c1-21-17-29(40)45-28-19-24(14-15-25(21)28)37-30(41)26(13-8-16-36-32(34)35)38-31(42)27(18-22-9-4-2-5-10-22)39-33(43)44-20-23-11-6-3-7-12-23\/h2-7,9-12,14-15,17,19,26-27H,8,13,16,18,20H2,1H3,(H,37,41)(H,38,42)(H,39,43)(H4,34,35,36)

InChIKey : ZZGDDBWFXDMARY-UHFFFAOYSA-N

Other name(s) : Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride, Z-FR-AMC, Cathepsin L substrate, AC1NNMUX, C9521_SIGMA


MW : 612.67

Formula : C33H36N6O6

CAS_number :

PubChem :

UniChem :

Iuphar :

Target

References (1)

Title : Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor - McLuskey_2010_J.Biol.Chem_285_39249
Author(s) : McLuskey K , Paterson NG , Bland ND , Isaacs NW , Mottram JC
Ref : Journal of Biological Chemistry , 285 :39249 , 2010
Abstract : McLuskey_2010_J.Biol.Chem_285_39249
ESTHER : McLuskey_2010_J.Biol.Chem_285_39249
PubMedSearch : McLuskey_2010_J.Biol.Chem_285_39249
PubMedID: 20926390
Gene_locus related to this paper: leima-OPB