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Substrate Report for: TSO

cytosolic epoxide hydrolase, cytosolic EH EPHX2


General
Type Epoxide
Chemical_Nomenclature (2S,3S)-2,3-diphenyloxirane
Canonical SMILES C1=CC=C(C=C1)C2C(O2)C3=CC=CC=C3
InChI InChI=1S/C14H12O/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12/h1-10,13-14H/t13-,14-/m0/s1
InChIKey ARCJQKUWGAZPFX-KBPBESRZSA-N
Other name(s) Trans-Stilbene oxide ; t-SO ; Trans-1,2-Diphenyloxirane ; (S,S)-stilbene oxide ; Trans-2,3-Diphenyloxirane ; UNII-D2L0AGD7AK ; Trans-alpha,alpha-Epoxydibenzyl
________________________________________________________________________________________________
MW|196.24
Formula|C14H12O
CAS_number|
PubChem|91504
UniChem|ARCJQKUWGAZPFX-KBPBESRZSA-N
IUPHAR|
Wikipedia|

Target
Families | TSO ligand of proteins in family: Epoxide_hydrolase
Protein | mouse-hyes, human-EPHX2

References:
Search PubMed for references concerning: TSO

2 more
    Title: Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei
    de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS
    Ref: Mol Biol Rep, 46:371, 2019 : PubMed

            

    Title: Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics
    Archelas A, Zhao W, Faure B, Iacazio G, Kotik M
    Ref: Archives of Biochemistry & Biophysics, 591:66, 2016 : PubMed

            

    Title: Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis
    Elfstrom LT, Widersten M
    Ref: Biochemistry, 45:205, 2006 : PubMed