Title : Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo - Tora_2020_J.Med.Chem_63_1660 |
Author(s) : Tora G , Kim SH , Pi Z , Johnson JA , Jiang J , Phillips M , Lloyd J , Abell LM , Lu H , Locke G , Adam LP , Taylor DS , Yin X , Behnia K , Zhao L , Yang R , Basso M , Caporuscio C , Chen AY , Liu E , Kirshgessner T , Onorato JM , Ryan C , Traeger SC , Gordon D , Wexler RR , Finlay HJ |
Ref : Journal of Medicinal Chemistry , 63 :1660 , 2020 |
Abstract : |
PubMedSearch : Tora_2020_J.Med.Chem_63_1660 |
PubMedID: 31990537 |
Title : Benzothiazole-based compounds as potent endothelial lipase inhibitors - Meng_2019_Bioorg.Med.Chem.Lett__126673 |
Author(s) : Meng W , Adam LP , Behnia K , Zhao L , Yang R , Kopcho LM , Locke GA , Taylor DS , Yin X , Wexler RR , Finlay H |
Ref : Bioorganic & Medicinal Chemistry Lett , :126673 , 2019 |
Abstract : |
PubMedSearch : Meng_2019_Bioorg.Med.Chem.Lett__126673 |
PubMedID: 31519373 |
Gene_locus related to this paper: human-LIPG |
Title : Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase - Kim_2019_Bioorg.Med.Chem.Lett_29_1918 |
Author(s) : Kim SH , Johnson JA , Jiang J , Parkhurst B , Phillips M , Pi Z , Qiao JX , Tora G , Ye Chen A , Liu E , Yin X , Yang R , Zhao L , Taylor DS , Basso M , Behnia K , Onorato J , Chen XQ , Abell LM , Lu H , Locke G , Caporuscio C , Adam LP , Gordon D , Wexler RR , Finlay HJ |
Ref : Bioorganic & Medicinal Chemistry Lett , 29 :1918 , 2019 |
Abstract : |
PubMedSearch : Kim_2019_Bioorg.Med.Chem.Lett_29_1918 |
PubMedID: 31176700 |
Gene_locus related to this paper: human-LIPG |
Title : Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase - Johnson_2018_ACS.Med.Chem.Lett_9_1263 |
Author(s) : Johnson JA , Tora G , Pi Z , Phillips M , Yin X , Yang R , Zhao L , Chen AY , Taylor DS , Basso M , Rose A , Behnia K , Onorato J , Chen XQ , Abell LM , Lu H , Locke G , Caporuscio C , Galella M , Adam LP , Gordon D , Wexler RR , Finlay HJ |
Ref : ACS Med Chem Lett , 9 :1263 , 2018 |
Abstract : |
PubMedSearch : Johnson_2018_ACS.Med.Chem.Lett_9_1263 |
PubMedID: 30613337 |
Gene_locus related to this paper: human-LIPG |