| Title : Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo - Tora_2020_J.Med.Chem_63_1660 |
| Author(s) : Tora G , Kim SH , Pi Z , Johnson JA , Jiang J , Phillips M , Lloyd J , Abell LM , Lu H , Locke G , Adam LP , Taylor DS , Yin X , Behnia K , Zhao L , Yang R , Basso M , Caporuscio C , Chen AY , Liu E , Kirshgessner T , Onorato JM , Ryan C , Traeger SC , Gordon D , Wexler RR , Finlay HJ |
| Ref : Journal of Medicinal Chemistry , 63 :1660 , 2020 |
| Abstract : |
| PubMedSearch : Tora_2020_J.Med.Chem_63_1660 |
| PubMedID: 31990537 |
| Title : Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase - Kim_2019_Bioorg.Med.Chem.Lett_29_1918 |
| Author(s) : Kim SH , Johnson JA , Jiang J , Parkhurst B , Phillips M , Pi Z , Qiao JX , Tora G , Ye Chen A , Liu E , Yin X , Yang R , Zhao L , Taylor DS , Basso M , Behnia K , Onorato J , Chen XQ , Abell LM , Lu H , Locke G , Caporuscio C , Adam LP , Gordon D , Wexler RR , Finlay HJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 29 :1918 , 2019 |
| Abstract : |
| PubMedSearch : Kim_2019_Bioorg.Med.Chem.Lett_29_1918 |
| PubMedID: 31176700 |
| Gene_locus related to this paper: human-LIPG |
| Title : Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase - Johnson_2018_ACS.Med.Chem.Lett_9_1263 |
| Author(s) : Johnson JA , Tora G , Pi Z , Phillips M , Yin X , Yang R , Zhao L , Chen AY , Taylor DS , Basso M , Rose A , Behnia K , Onorato J , Chen XQ , Abell LM , Lu H , Locke G , Caporuscio C , Galella M , Adam LP , Gordon D , Wexler RR , Finlay HJ |
| Ref : ACS Med Chem Lett , 9 :1263 , 2018 |
| Abstract : |
| PubMedSearch : Johnson_2018_ACS.Med.Chem.Lett_9_1263 |
| PubMedID: 30613337 |
| Gene_locus related to this paper: human-LIPG |
| Title : Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections - Fura_2009_Drug.Metab.Dispos_37_1164 |
| Author(s) : Fura A , Khanna A , Vyas V , Koplowitz B , Chang SY , Caporuscio C , Boulton DW , Christopher LJ , Chadwick KD , Hamann LG , Humphreys WG , Kirby M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 37 :1164 , 2009 |
| Abstract : |
| PubMedSearch : Fura_2009_Drug.Metab.Dispos_37_1164 |
| PubMedID: 19251818 |