| Title : Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy - Turner_2025_PLoS.One_20_e0318508 |
| Author(s) : Turner SR , Timperley CM , Bird M , Green AC , Price ME , Rice H , Chad JE , Tattersall JEH |
| Ref : PLoS ONE , 20 :e0318508 , 2025 |
| Abstract : |
| PubMedSearch : Turner_2025_PLoS.One_20_e0318508 |
| PubMedID: 39999134 |
| Title : Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships - Amend_2024_Toxicology__153741 |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicology , :153741 , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicology__153741 |
| PubMedID: 38311098 |
| Title : The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization - Amend_2024_Toxicol.Lett__ |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicol.Lett__ |
| PubMedID: 38723915 |
| Title : Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice - Kassa_2022_Toxics_10_ |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxics , 10 : , 2022 |
| Abstract : |
| PubMedSearch : Kassa_2022_Toxics_10_ |
| PubMedID: 35448453 |
| Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__ |
| Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC |
| Ref : Toxicol Lett , : , 2021 |
| Abstract : |
| PubMedSearch : Epstein_2021_Toxicol.Lett__ |
| PubMedID: 33482275 |
| Title : Two cases of non-alcoholic fatty liver disease caused by biallelic ABHD5 mutations - |
| Author(s) : Adant I , Declercq M , Bird M , Bauters M , Boeckx N , Devriendt K , Cassiman D , Witters P |
| Ref : Journal of Hepatology , 72 :1030 , 2020 |
| PubMedID: 32107051 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Assessment of false transmitters as treatments for nerve agent poisoning - Whitmore_2020_Toxicol.Lett_321_21 |
| Author(s) : Whitmore C , Lindsay CD , Bird M , Gore SJ , Rice H , Williams RL , Timperley CM , Green AC |
| Ref : Toxicol Lett , 321 :21 , 2020 |
| Abstract : |
| PubMedSearch : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedID: 31830555 |
| Title : Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment - Kassa_2020_Toxicol.Mech.Methods_30_703 |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxicol Mech Methods , 30 :703 , 2020 |
| Abstract : |
| PubMedSearch : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedID: 32878547 |
| Title : Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig - Price_2016_Toxicol.Lett_244_154 |
| Author(s) : Price ME , Docx CJ , Rice H , Fairhall SJ , Poole SJ , Bird M , Whiley L , Flint DP , Green AC , Timperley CM , Tattersall JE |
| Ref : Toxicol Lett , 244 :154 , 2016 |
| Abstract : |
| PubMedSearch : Price_2016_Toxicol.Lett_244_154 |
| PubMedID: 26325216 |
| Title : Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice - Kassa_2016_Toxicol.Mech.Methods_26_334 |
| Author(s) : Kassa J , Pohanka M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Mech Methods , 26 :334 , 2016 |
| Abstract : |
| PubMedSearch : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedID: 27097774 |
| Title : Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines - Ring_2015_PLoS.One_10_e0135811 |
| Author(s) : Ring A , Strom BO , Turner SR , Timperley CM , Bird M , Green AC , Chad JE , Worek F , Tattersall JE |
| Ref : PLoS ONE , 10 :e0135811 , 2015 |
| Abstract : |
| PubMedSearch : Ring_2015_PLoS.One_10_e0135811 |
| PubMedID: 26274808 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : 1,1'-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy - Timperley_2012_Medchemcomm_3_352 |
| Author(s) : Timperley CM , Bird M , Green C , Price ME , Chad JE , Turner SR , Tattersall JEH |
| Ref : Medchemcomm , 3 :352 , 2012 |
| Abstract : |
| PubMedSearch : Timperley_2012_Medchemcomm_3_352 |
| PubMedID: |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist - Turner_2011_Toxicol.Lett_206_105 |
| Author(s) : Turner SR , Chad JE , Price M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Lett , 206 :105 , 2011 |
| Abstract : |
| PubMedSearch : Turner_2011_Toxicol.Lett_206_105 |
| PubMedID: 21641979 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |