| Title : The synthesis and influence of the novel bispyridinium compound LB1 on the effectiveness of the standard antidotal treatment of organophosphorus nerve agent intoxicated mice and some structure-activity considerations - Kassa_2025_Chem.Biol.Interact__111470 |
| Author(s) : Kassa J , Ambler RE , Brown LJ , Cummins J , Green AC , Timperley CM |
| Ref : Chemico-Biological Interactions , :111470 , 2025 |
| Abstract : |
| PubMedSearch : Kassa_2025_Chem.Biol.Interact__111470 |
| PubMedID: 40058717 |
| Title : Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy - Turner_2025_PLoS.One_20_e0318508 |
| Author(s) : Turner SR , Timperley CM , Bird M , Green AC , Price ME , Rice H , Chad JE , Tattersall JEH |
| Ref : PLoS ONE , 20 :e0318508 , 2025 |
| Abstract : |
| PubMedSearch : Turner_2025_PLoS.One_20_e0318508 |
| PubMedID: 39999134 |
| Title : The synthesis and influence of the novel bispyridinium compound LB1 on the effectiveness of the standard antidotal treatment of organophosphorus nerve agent intoxicated mice and some structure-activity considerations - Kassa_2025_Chem.Biol.Interact__111470 |
| Author(s) : Kassa J , Ambler RE , Brown LJ , Cummins J , Green AC , Timperley CM |
| Ref : Chemico-Biological Interactions , :111470 , 2025 |
| Abstract : |
| PubMedSearch : Kassa_2025_Chem.Biol.Interact__111470 |
| PubMedID: 40058717 |
| Title : Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy - Turner_2025_PLoS.One_20_e0318508 |
| Author(s) : Turner SR , Timperley CM , Bird M , Green AC , Price ME , Rice H , Chad JE , Tattersall JEH |
| Ref : PLoS ONE , 20 :e0318508 , 2025 |
| Abstract : |
| PubMedSearch : Turner_2025_PLoS.One_20_e0318508 |
| PubMedID: 39999134 |
| Title : The synthesis and influence of the novel bispyridinium compound LB1 on the effectiveness of the standard antidotal treatment of organophosphorus nerve agent intoxicated mice and some structure-activity considerations - Kassa_2025_Chem.Biol.Interact__111470 |
| Author(s) : Kassa J , Ambler RE , Brown LJ , Cummins J , Green AC , Timperley CM |
| Ref : Chemico-Biological Interactions , :111470 , 2025 |
| Abstract : |
| PubMedSearch : Kassa_2025_Chem.Biol.Interact__111470 |
| PubMedID: 40058717 |
| Title : Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy - Turner_2025_PLoS.One_20_e0318508 |
| Author(s) : Turner SR , Timperley CM , Bird M , Green AC , Price ME , Rice H , Chad JE , Tattersall JEH |
| Ref : PLoS ONE , 20 :e0318508 , 2025 |
| Abstract : |
| PubMedSearch : Turner_2025_PLoS.One_20_e0318508 |
| PubMedID: 39999134 |
| Title : Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships - Amend_2024_Toxicology__153741 |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicology , :153741 , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicology__153741 |
| PubMedID: 38311098 |
| Title : The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization - Amend_2024_Toxicol.Lett__ |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicol.Lett__ |
| PubMedID: 38723915 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships - Amend_2024_Toxicology__153741 |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicology , :153741 , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicology__153741 |
| PubMedID: 38311098 |
| Title : The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization - Amend_2024_Toxicol.Lett__ |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicol.Lett__ |
| PubMedID: 38723915 |
| Title : Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships - Amend_2024_Toxicology__153741 |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicology , :153741 , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicology__153741 |
| PubMedID: 38311098 |
| Title : The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization - Amend_2024_Toxicol.Lett__ |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Amend_2024_Toxicol.Lett__ |
| PubMedID: 38723915 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice - Kassa_2022_Toxics_10_ |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxics , 10 : , 2022 |
| Abstract : |
| PubMedSearch : Kassa_2022_Toxics_10_ |
| PubMedID: 35448453 |
| Title : Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice - Kassa_2022_Toxics_10_ |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxics , 10 : , 2022 |
| Abstract : |
| PubMedSearch : Kassa_2022_Toxics_10_ |
| PubMedID: 35448453 |
| Title : Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice - Kassa_2022_Toxics_10_ |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxics , 10 : , 2022 |
| Abstract : |
| PubMedSearch : Kassa_2022_Toxics_10_ |
| PubMedID: 35448453 |
| Title : Reply to Comment on Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - Timperley_2021_J.Chem.Educ_98_1468 |
| Author(s) : Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 98 :1468 , 2021 |
| Abstract : |
| PubMedSearch : Timperley_2021_J.Chem.Educ_98_1468 |
| PubMedID: |
| Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__ |
| Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC |
| Ref : Toxicol Lett , : , 2021 |
| Abstract : |
| PubMedSearch : Epstein_2021_Toxicol.Lett__ |
| PubMedID: 33482275 |
| Title : Reply to Comment on Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - Timperley_2021_J.Chem.Educ_98_1468 |
| Author(s) : Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 98 :1468 , 2021 |
| Abstract : |
| PubMedSearch : Timperley_2021_J.Chem.Educ_98_1468 |
| PubMedID: |
| Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__ |
| Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC |
| Ref : Toxicol Lett , : , 2021 |
| Abstract : |
| PubMedSearch : Epstein_2021_Toxicol.Lett__ |
| PubMedID: 33482275 |
| Title : Reply to Comment on Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - Timperley_2021_J.Chem.Educ_98_1468 |
| Author(s) : Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 98 :1468 , 2021 |
| Abstract : |
| PubMedSearch : Timperley_2021_J.Chem.Educ_98_1468 |
| PubMedID: |
| Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__ |
| Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC |
| Ref : Toxicol Lett , : , 2021 |
| Abstract : |
| PubMedSearch : Epstein_2021_Toxicol.Lett__ |
| PubMedID: 33482275 |
| Title : Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - |
| Author(s) : Pontes , Schneider J , Brud P , Benderitter L , Fourie B , Tang C , Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 97 :1715 , 2020 |
| PubMedID: |
| Title : Assessment of false transmitters as treatments for nerve agent poisoning - Whitmore_2020_Toxicol.Lett_321_21 |
| Author(s) : Whitmore C , Lindsay CD , Bird M , Gore SJ , Rice H , Williams RL , Timperley CM , Green AC |
| Ref : Toxicol Lett , 321 :21 , 2020 |
| Abstract : |
| PubMedSearch : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedID: 31830555 |
| Title : Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - |
| Author(s) : Pontes , Schneider J , Brud P , Benderitter L , Fourie B , Tang C , Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 97 :1715 , 2020 |
| PubMedID: |
| Title : Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment - Kassa_2020_Toxicol.Mech.Methods_30_703 |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxicol Mech Methods , 30 :703 , 2020 |
| Abstract : |
| PubMedSearch : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedID: 32878547 |
| Title : Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - |
| Author(s) : Pontes , Schneider J , Brud P , Benderitter L , Fourie B , Tang C , Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 97 :1715 , 2020 |
| PubMedID: |
| Title : Assessment of false transmitters as treatments for nerve agent poisoning - Whitmore_2020_Toxicol.Lett_321_21 |
| Author(s) : Whitmore C , Lindsay CD , Bird M , Gore SJ , Rice H , Williams RL , Timperley CM , Green AC |
| Ref : Toxicol Lett , 321 :21 , 2020 |
| Abstract : |
| PubMedSearch : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedID: 31830555 |
| Title : Assessment of false transmitters as treatments for nerve agent poisoning - Whitmore_2020_Toxicol.Lett_321_21 |
| Author(s) : Whitmore C , Lindsay CD , Bird M , Gore SJ , Rice H , Williams RL , Timperley CM , Green AC |
| Ref : Toxicol Lett , 321 :21 , 2020 |
| Abstract : |
| PubMedSearch : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedID: 31830555 |
| Title : Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment - Kassa_2020_Toxicol.Mech.Methods_30_703 |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxicol Mech Methods , 30 :703 , 2020 |
| Abstract : |
| PubMedSearch : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedID: 32878547 |
| Title : Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment - Kassa_2020_Toxicol.Mech.Methods_30_703 |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxicol Mech Methods , 30 :703 , 2020 |
| Abstract : |
| PubMedSearch : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedID: 32878547 |
| Title : Advice on assistance and protection from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents - Timperley_2019_Toxicology_413_13 |
| Author(s) : Timperley CM , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Fusaro Mourao NM , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S , Forman JE , Alwan WS , Suri V |
| Ref : Toxicology , 413 :13 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_413_13 |
| PubMedID: 30500381 |
| Title : Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents - Timperley_2019_Toxicology_415_56 |
| Author(s) : Timperley CM , Forman JE , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Mourao NMF , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S |
| Ref : Toxicology , 415 :56 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_415_56 |
| PubMedID: 30639304 |
| Title : Advice on assistance and protection from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents - Timperley_2019_Toxicology_413_13 |
| Author(s) : Timperley CM , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Fusaro Mourao NM , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S , Forman JE , Alwan WS , Suri V |
| Ref : Toxicology , 413 :13 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_413_13 |
| PubMedID: 30500381 |
| Title : Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents - Timperley_2019_Toxicology_415_56 |
| Author(s) : Timperley CM , Forman JE , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Mourao NMF , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S |
| Ref : Toxicology , 415 :56 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_415_56 |
| PubMedID: 30639304 |
| Title : Advice on assistance and protection from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents - Timperley_2019_Toxicology_413_13 |
| Author(s) : Timperley CM , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Fusaro Mourao NM , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S , Forman JE , Alwan WS , Suri V |
| Ref : Toxicology , 413 :13 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_413_13 |
| PubMedID: 30500381 |
| Title : Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents - Timperley_2019_Toxicology_415_56 |
| Author(s) : Timperley CM , Forman JE , Abdollahi M , Al-Amri AS , Baulig A , Benachour D , Borrett V , Carino FA , Geist M , Gonzalez D , Kane W , Kovarik Z , Martinez-Alvarez R , Mourao NMF , Neffe S , Raza SK , Rubaylo V , Suarez AG , Takeuchi K , Tang C , Trifiro F , van Straten FM , Vanninen PS , Vucinic S , Zaitsev V , Zafar-Uz-Zaman M , Zina MS , Holen S |
| Ref : Toxicology , 415 :56 , 2019 |
| Abstract : |
| PubMedSearch : Timperley_2019_Toxicology_415_56 |
| PubMedID: 30639304 |
| Title : Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig - Price_2016_Toxicol.Lett_244_154 |
| Author(s) : Price ME , Docx CJ , Rice H , Fairhall SJ , Poole SJ , Bird M , Whiley L , Flint DP , Green AC , Timperley CM , Tattersall JE |
| Ref : Toxicol Lett , 244 :154 , 2016 |
| Abstract : |
| PubMedSearch : Price_2016_Toxicol.Lett_244_154 |
| PubMedID: 26325216 |
| Title : Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice - Kassa_2016_Toxicol.Mech.Methods_26_334 |
| Author(s) : Kassa J , Pohanka M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Mech Methods , 26 :334 , 2016 |
| Abstract : |
| PubMedSearch : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedID: 27097774 |
| Title : Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig - Price_2016_Toxicol.Lett_244_154 |
| Author(s) : Price ME , Docx CJ , Rice H , Fairhall SJ , Poole SJ , Bird M , Whiley L , Flint DP , Green AC , Timperley CM , Tattersall JE |
| Ref : Toxicol Lett , 244 :154 , 2016 |
| Abstract : |
| PubMedSearch : Price_2016_Toxicol.Lett_244_154 |
| PubMedID: 26325216 |
| Title : Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice - Kassa_2016_Toxicol.Mech.Methods_26_334 |
| Author(s) : Kassa J , Pohanka M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Mech Methods , 26 :334 , 2016 |
| Abstract : |
| PubMedSearch : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedID: 27097774 |
| Title : Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig - Price_2016_Toxicol.Lett_244_154 |
| Author(s) : Price ME , Docx CJ , Rice H , Fairhall SJ , Poole SJ , Bird M , Whiley L , Flint DP , Green AC , Timperley CM , Tattersall JE |
| Ref : Toxicol Lett , 244 :154 , 2016 |
| Abstract : |
| PubMedSearch : Price_2016_Toxicol.Lett_244_154 |
| PubMedID: 26325216 |
| Title : Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice - Kassa_2016_Toxicol.Mech.Methods_26_334 |
| Author(s) : Kassa J , Pohanka M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Mech Methods , 26 :334 , 2016 |
| Abstract : |
| PubMedSearch : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedID: 27097774 |
| Title : Toxicity and medical countermeasure studies on the organophosphorus nerve agents VM and VX - Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| Author(s) : Rice H , Dalton CH , Price ME , Graham SJ , Green AC , Jenner J , Groombridge HJ , Timperley CM |
| Ref : Proc Math Phys Eng Sci , 471 :20140891 , 2015 |
| Abstract : |
| PubMedSearch : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| PubMedID: 27547080 |
| Title : Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines - Ring_2015_PLoS.One_10_e0135811 |
| Author(s) : Ring A , Strom BO , Turner SR , Timperley CM , Bird M , Green AC , Chad JE , Worek F , Tattersall JE |
| Ref : PLoS ONE , 10 :e0135811 , 2015 |
| Abstract : |
| PubMedSearch : Ring_2015_PLoS.One_10_e0135811 |
| PubMedID: 26274808 |
| Title : Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines - Ring_2015_PLoS.One_10_e0135811 |
| Author(s) : Ring A , Strom BO , Turner SR , Timperley CM , Bird M , Green AC , Chad JE , Worek F , Tattersall JE |
| Ref : PLoS ONE , 10 :e0135811 , 2015 |
| Abstract : |
| PubMedSearch : Ring_2015_PLoS.One_10_e0135811 |
| PubMedID: 26274808 |
| Title : Toxicity and medical countermeasure studies on the organophosphorus nerve agents VM and VX - Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| Author(s) : Rice H , Dalton CH , Price ME , Graham SJ , Green AC , Jenner J , Groombridge HJ , Timperley CM |
| Ref : Proc Math Phys Eng Sci , 471 :20140891 , 2015 |
| Abstract : |
| PubMedSearch : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| PubMedID: 27547080 |
| Title : Toxicity and medical countermeasure studies on the organophosphorus nerve agents VM and VX - Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| Author(s) : Rice H , Dalton CH , Price ME , Graham SJ , Green AC , Jenner J , Groombridge HJ , Timperley CM |
| Ref : Proc Math Phys Eng Sci , 471 :20140891 , 2015 |
| Abstract : |
| PubMedSearch : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| PubMedID: 27547080 |
| Title : Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines - Ring_2015_PLoS.One_10_e0135811 |
| Author(s) : Ring A , Strom BO , Turner SR , Timperley CM , Bird M , Green AC , Chad JE , Worek F , Tattersall JE |
| Ref : PLoS ONE , 10 :e0135811 , 2015 |
| Abstract : |
| PubMedSearch : Ring_2015_PLoS.One_10_e0135811 |
| PubMedID: 26274808 |
| Title : Fate of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) on soil following accelerant-based fire and liquid decontamination - Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Riches JR |
| Ref : Anal Bioanal Chem , 406 :5121 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| PubMedID: 24972874 |
| Title : Evidence of VX nerve agent use from contaminated white mustard plants - Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Baker MJ |
| Ref : Proc Math Phys Eng Sci , 470 :20140076 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| PubMedID: 25104906 |
| Title : Evidence of VX nerve agent use from contaminated white mustard plants - Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Baker MJ |
| Ref : Proc Math Phys Eng Sci , 470 :20140076 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| PubMedID: 25104906 |
| Title : Fate of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) on soil following accelerant-based fire and liquid decontamination - Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Riches JR |
| Ref : Anal Bioanal Chem , 406 :5121 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| PubMedID: 24972874 |
| Title : Fate of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) on soil following accelerant-based fire and liquid decontamination - Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Riches JR |
| Ref : Anal Bioanal Chem , 406 :5121 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Anal.Bioanal.Chem_406_5121 |
| PubMedID: 24972874 |
| Title : Evidence of VX nerve agent use from contaminated white mustard plants - Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Baker MJ |
| Ref : Proc Math Phys Eng Sci , 470 :20140076 , 2014 |
| Abstract : |
| PubMedSearch : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| PubMedID: 25104906 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : 1,1'-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy - Timperley_2012_Medchemcomm_3_352 |
| Author(s) : Timperley CM , Bird M , Green C , Price ME , Chad JE , Turner SR , Tattersall JEH |
| Ref : Medchemcomm , 3 :352 , 2012 |
| Abstract : |
| PubMedSearch : Timperley_2012_Medchemcomm_3_352 |
| PubMedID: |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : 1,1'-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy - Timperley_2012_Medchemcomm_3_352 |
| Author(s) : Timperley CM , Bird M , Green C , Price ME , Chad JE , Turner SR , Tattersall JEH |
| Ref : Medchemcomm , 3 :352 , 2012 |
| Abstract : |
| PubMedSearch : Timperley_2012_Medchemcomm_3_352 |
| PubMedID: |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : 1,1'-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy - Timperley_2012_Medchemcomm_3_352 |
| Author(s) : Timperley CM , Bird M , Green C , Price ME , Chad JE , Turner SR , Tattersall JEH |
| Ref : Medchemcomm , 3 :352 , 2012 |
| Abstract : |
| PubMedSearch : Timperley_2012_Medchemcomm_3_352 |
| PubMedID: |
| Title : Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist - Turner_2011_Toxicol.Lett_206_105 |
| Author(s) : Turner SR , Chad JE , Price M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Lett , 206 :105 , 2011 |
| Abstract : |
| PubMedSearch : Turner_2011_Toxicol.Lett_206_105 |
| PubMedID: 21641979 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891 |
| Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O |
| Ref : Chemical Research in Toxicology , 24 :1891 , 2011 |
| Abstract : |
| PubMedSearch : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| PubMedID: 21875074 |
| Gene_locus related to this paper: mouse-Ces1c |
| Title : Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist - Turner_2011_Toxicol.Lett_206_105 |
| Author(s) : Turner SR , Chad JE , Price M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Lett , 206 :105 , 2011 |
| Abstract : |
| PubMedSearch : Turner_2011_Toxicol.Lett_206_105 |
| PubMedID: 21641979 |
| Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891 |
| Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O |
| Ref : Chemical Research in Toxicology , 24 :1891 , 2011 |
| Abstract : |
| PubMedSearch : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| PubMedID: 21875074 |
| Gene_locus related to this paper: mouse-Ces1c |
| Title : Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist - Turner_2011_Toxicol.Lett_206_105 |
| Author(s) : Turner SR , Chad JE , Price M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Lett , 206 :105 , 2011 |
| Abstract : |
| PubMedSearch : Turner_2011_Toxicol.Lett_206_105 |
| PubMedID: 21641979 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891 |
| Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O |
| Ref : Chemical Research in Toxicology , 24 :1891 , 2011 |
| Abstract : |
| PubMedSearch : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| PubMedID: 21875074 |
| Gene_locus related to this paper: mouse-Ces1c |
| Title : Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase - Blum_2008_Biochemistry_47_5216 |
| Author(s) : Blum MM , Timperley CM , Williams GR , Thiermann H , Worek F |
| Ref : Biochemistry , 47 :5216 , 2008 |
| Abstract : |
| PubMedSearch : Blum_2008_Biochemistry_47_5216 |
| PubMedID: 18396898 |
| Title : Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase - Blum_2008_Biochemistry_47_5216 |
| Author(s) : Blum MM , Timperley CM , Williams GR , Thiermann H , Worek F |
| Ref : Biochemistry , 47 :5216 , 2008 |
| Abstract : |
| PubMedSearch : Blum_2008_Biochemistry_47_5216 |
| PubMedID: 18396898 |
| Title : Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase - Blum_2008_Biochemistry_47_5216 |
| Author(s) : Blum MM , Timperley CM , Williams GR , Thiermann H , Worek F |
| Ref : Biochemistry , 47 :5216 , 2008 |
| Abstract : |
| PubMedSearch : Blum_2008_Biochemistry_47_5216 |
| PubMedID: 18396898 |
| Title : Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents - Briseno-Roa_2006_J.Med.Chem_49_246 |
| Author(s) : Briseno-Roa L , Hill J , Notman S , Sellers D , Smith AP , Timperley CM , Wetherell J , Williams NH , Williams GR , Fersht AR , Griffiths AD |
| Ref : Journal of Medicinal Chemistry , 49 :246 , 2006 |
| Abstract : |
| PubMedSearch : Briseno-Roa_2006_J.Med.Chem_49_246 |
| PubMedID: 16392809 |
| Title : Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents - Briseno-Roa_2006_J.Med.Chem_49_246 |
| Author(s) : Briseno-Roa L , Hill J , Notman S , Sellers D , Smith AP , Timperley CM , Wetherell J , Williams NH , Williams GR , Fersht AR , Griffiths AD |
| Ref : Journal of Medicinal Chemistry , 49 :246 , 2006 |
| Abstract : |
| PubMedSearch : Briseno-Roa_2006_J.Med.Chem_49_246 |
| PubMedID: 16392809 |
| Title : Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents - Briseno-Roa_2006_J.Med.Chem_49_246 |
| Author(s) : Briseno-Roa L , Hill J , Notman S , Sellers D , Smith AP , Timperley CM , Wetherell J , Williams NH , Williams GR , Fersht AR , Griffiths AD |
| Ref : Journal of Medicinal Chemistry , 49 :246 , 2006 |
| Abstract : |
| PubMedSearch : Briseno-Roa_2006_J.Med.Chem_49_246 |
| PubMedID: 16392809 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |