| Title : Effects of Oral ALZ-801\/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease - Hey_2024_Drugs__ |
| Author(s) : Hey JA , Abushakra S , Blennow K , Reiman EM , Hort J , Prins ND , Sheardova K , Kesslak P , Shen L , Zhu X , Albayrak A , Paul J , Schaefer JF , Power A , Tolar M |
| Ref : Drugs , : , 2024 |
| Abstract : |
| PubMedSearch : Hey_2024_Drugs__ |
| PubMedID: 38902571 |
| Title : Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity - Schilling_2023_Acta.Neuropathol.Commun_11_87 |
| Author(s) : Schilling S , Pradhan A , Heesch A , Helbig A , Blennow K , Koch C , Bertgen L , Koo EH , Brinkmalm G , Zetterberg H , Kins S , Eggert S |
| Ref : Acta Neuropathologica Commun , 11 :87 , 2023 |
| Abstract : |
| PubMedSearch : Schilling_2023_Acta.Neuropathol.Commun_11_87 |
| PubMedID: 37259128 |
| Title : Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease - Brinkley_2022_Front.Neurosci_16_906539 |
| Author(s) : Brinkley TE , Leng I , Register TC , Neth BJ , Zetterberg H , Blennow K , Craft S |
| Ref : Front Neurosci , 16 :906539 , 2022 |
| Abstract : |
| PubMedSearch : Brinkley_2022_Front.Neurosci_16_906539 |
| PubMedID: 35720727 |
| Title : Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease - Bateman_2022_Alzheimers.Res.Ther_14_178 |
| Author(s) : Bateman RJ , Cummings J , Schobel S , Salloway S , Vellas B , Boada M , Black SE , Blennow K , Fontoura P , Klein G , Assuncao SS , Smith J , Doody RS |
| Ref : Alzheimers Res Ther , 14 :178 , 2022 |
| Abstract : |
| PubMedSearch : Bateman_2022_Alzheimers.Res.Ther_14_178 |
| PubMedID: 36447240 |
| Title : Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry - Camporesi_2022_EBioMedicine_75_103793 |
| Author(s) : Camporesi E , Nilsson J , Vrillon A , Cognat E , Hourregue C , Zetterberg H , Blennow K , Becker B , Brinkmalm A , Paquet C , Brinkmalm G |
| Ref : EBioMedicine , 75 :103793 , 2022 |
| Abstract : |
| PubMedSearch : Camporesi_2022_EBioMedicine_75_103793 |
| PubMedID: 34990894 |
| Title : Evidence of upregulation of the cholinergic anti-inflammatory pathway in late-life depression - Pomara_2021_J.Affect.Disord_286_275 |
| Author(s) : Pomara N , Bruno D , Plaska CR , Pillai A , Ramos-Cejudo J , Osorio R , Imbimbo BP , Heslegrave A , Zetterberg H , Blennow K |
| Ref : J Affect Disord , 286 :275 , 2021 |
| Abstract : |
| PubMedSearch : Pomara_2021_J.Affect.Disord_286_275 |
| PubMedID: 33756305 |
| Title : Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers - Camporesi_2021_Acta.Neuropathol.Commun_9_19 |
| Author(s) : Camporesi E , Lashley T , Gobom J , Lantero-Rodriguez J , Hansson O , Zetterberg H , Blennow K , Becker B |
| Ref : Acta Neuropathologica Commun , 9 :19 , 2021 |
| Abstract : |
| PubMedSearch : Camporesi_2021_Acta.Neuropathol.Commun_9_19 |
| PubMedID: 33522967 |
| Title : Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study - Tofiq_2021_J.Alzheimers.Dis__ |
| Author(s) : Tofiq A , Zetterberg H , Blennow K , Basun H , Cederholm T , Eriksdotter M , Faxen-Irving G , Hjorth E , Jerneren F , Schultzberg M , Wahlund LO , Palmblad J , Freund-Levi Y |
| Ref : J Alzheimers Dis , : , 2021 |
| Abstract : |
| PubMedSearch : Tofiq_2021_J.Alzheimers.Dis__ |
| PubMedID: 34420949 |
| Title : [Alzheimer's disease - the most common cause of dementia] - Bogdanovic_2020_Lakartidningen_117_ |
| Author(s) : Bogdanovic N , Hansson O , Zetterberg H , Basun H , Ingelsson M , Lannfelt L , Blennow K |
| Ref : Lakartidningen , 117 : , 2020 |
| Abstract : |
| PubMedSearch : Bogdanovic_2020_Lakartidningen_117_ |
| PubMedID: 32154904 |
| Title : Cerebro-spinal fluid biomarker levels: phosphorylated tau (T) and total tau (N) as markers for rate of progression in Alzheimer's disease - Wattmo_2020_BMC.Neurol_20_10 |
| Author(s) : Wattmo C , Blennow K , Hansson O |
| Ref : BMC Neurol , 20 :10 , 2020 |
| Abstract : |
| PubMedSearch : Wattmo_2020_BMC.Neurol_20_10 |
| PubMedID: 31918679 |
| Title : Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid - Bloniecki_2017_J.Alzheimers.Dis_57_387 |
| Author(s) : Bloniecki V , Aarsland D , Blennow K , Cummings J , Falahati F , Winblad B , Freund-Levi Y |
| Ref : J Alzheimers Dis , 57 :387 , 2017 |
| Abstract : |
| PubMedSearch : Bloniecki_2017_J.Alzheimers.Dis_57_387 |
| PubMedID: 28269767 |
| Title : Reduced cerebrospinal fluid concentration of interleukin-12\/23 subunit p40 in patients with cognitive impairment - Johansson_2017_PLoS.One_12_e0176760 |
| Author(s) : Johansson P , Almqvist EG , Wallin A , Johansson JO , Andreasson U , Blennow K , Zetterberg H , Svensson J |
| Ref : PLoS ONE , 12 :e0176760 , 2017 |
| Abstract : |
| PubMedSearch : Johansson_2017_PLoS.One_12_e0176760 |
| PubMedID: 28464009 |
| Title : Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device - Eyjolfsdottir_2016_Alzheimers.Res.Ther_8_30 |
| Author(s) : Eyjolfsdottir H , Eriksdotter M , Linderoth B , Lind G , Juliusson B , Kusk P , Almkvist O , Andreasen N , Blennow K , Ferreira D , Westman E , Nennesmo I , Karami A , Darreh-Shori T , Kadir A , Nordberg A , Sundstrom E , Wahlund LO , Wall A , Wiberg M , Winblad B , Seiger A , Wahlberg L , Almqvist P |
| Ref : Alzheimers Res Ther , 8 :30 , 2016 |
| Abstract : |
| PubMedSearch : Eyjolfsdottir_2016_Alzheimers.Res.Ther_8_30 |
| PubMedID: 27389402 |
| Title : Brain changes in Alzheimer's disease patients with implanted encapsulated cells releasing nerve growth factor - Ferreira_2015_J.Alzheimers.Dis_43_1059 |
| Author(s) : Ferreira D , Westman E , Eyjolfsdottir H , Almqvist P , Lind G , Linderoth B , Seiger A , Blennow K , Karami A , Darreh-Shori T , Wiberg M , Simmons A , Wahlund LO , Wahlberg L , Eriksdotter M |
| Ref : J Alzheimers Dis , 43 :1059 , 2015 |
| Abstract : |
| PubMedSearch : Ferreira_2015_J.Alzheimers.Dis_43_1059 |
| PubMedID: 25147108 |
| Title : Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease - Karami_2015_Alzheimers.Dement_11_1316 |
| Author(s) : Karami A , Eyjolfsdottir H , Vijayaraghavan S , Lind G , Almqvist P , Kadir A , Linderoth B , Andreasen N , Blennow K , Wall A , Westman E , Ferreira D , Kristoffersen Wiberg M , Wahlund LO , Seiger A , Nordberg A , Wahlberg L , Darreh-Shori T , Eriksdotter M |
| Ref : Alzheimers Dement , 11 :1316 , 2015 |
| Abstract : |
| PubMedSearch : Karami_2015_Alzheimers.Dement_11_1316 |
| PubMedID: 25676388 |
| Title : Cerebrospinal Fluid (CSF) 25-Hydroxyvitamin D Concentration and CSF Acetylcholinesterase Activity Are Reduced in Patients with Alzheimer's Disease - Johansson_2013_PLoS.One_8_e81989 |
| Author(s) : Johansson P , Almqvist EG , Johansson JO , Mattsson N , Andreasson U , Hansson O , Wallin A , Blennow K , Zetterberg H , Svensson J |
| Ref : PLoS ONE , 8 :e81989 , 2013 |
| Abstract : |
| PubMedSearch : Johansson_2013_PLoS.One_8_e81989 |
| PubMedID: 24312390 |
| Title : Dose and plasma concentration of galantamine in Alzheimer's disease - clinical application - Wattmo_2013_Alzheimers.Res.Ther_5_2 |
| Author(s) : Wattmo C , Jedenius E , Blennow K , Wallin AK |
| Ref : Alzheimers Res Ther , 5 :2 , 2013 |
| Abstract : |
| PubMedSearch : Wattmo_2013_Alzheimers.Res.Ther_5_2 |
| PubMedID: 23286718 |
| Title : CSF Presenilin-1 complexes are increased in Alzheimer's disease - Garcia-Ayllon_2013_Acta.Neuropathol.Commun_1_46 |
| Author(s) : Garcia-Ayllon MS , Campanari ML , Brinkmalm G , Rabano A , Alom J , Saura CA , Andreasen N , Blennow K , Saez-Valero J |
| Ref : Acta Neuropathologica Commun , 1 :46 , 2013 |
| Abstract : |
| PubMedSearch : Garcia-Ayllon_2013_Acta.Neuropathol.Commun_1_46 |
| PubMedID: 24252417 |
| Title : Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease - Hoglund_2012_J.Alzheimers.Dis_32_939 |
| Author(s) : Hoglund K , Bogstedt A , Fabre S , Aziz A , Annas P , Basun H , Minthon L , Lannfelt L , Blennow K , Andreasen N |
| Ref : J Alzheimers Dis , 32 :939 , 2012 |
| Abstract : |
| PubMedSearch : Hoglund_2012_J.Alzheimers.Dis_32_939 |
| PubMedID: 22936008 |
| Title : The apolipoprotein E epsilon4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase - Darreh-Shori_2011_Neurobiol.Aging_32_1236 |
| Author(s) : Darreh-Shori T , Modiri N , Blennow K , Baza S , Kamil C , Ahmed H , Andreasen N , Nordberg A |
| Ref : Neurobiology of Aging , 32 :1236 , 2011 |
| Abstract : |
| PubMedSearch : Darreh-Shori_2011_Neurobiol.Aging_32_1236 |
| PubMedID: 19713000 |
| Title : Changes in CSF acetyl- and butyrylcholinesterase activity after long-term treatment with AChE inhibitors in Alzheimer's disease - Parnetti_2011_Acta.Neurol.Scand_124_122 |
| Author(s) : Parnetti L , Chiasserini D , Andreasson U , Ohlson M , Huls C , Zetterberg H , Minthon L , Wallin AK , Andreasen N , Talesa VN , Blennow K |
| Ref : Acta Neurologica Scandinavica , 124 :122 , 2011 |
| Abstract : |
| PubMedSearch : Parnetti_2011_Acta.Neurol.Scand_124_122 |
| PubMedID: 20880294 |
| Title : Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo - Darreh-Shori_2011_Neurobiol.Aging_32_2320 e15 |
| Author(s) : Darreh-Shori T , Forsberg A , Modiri N , Andreasen N , Blennow K , Kamil C , Ahmed H , Almkvist O , Langstrom B , Nordberg A |
| Ref : Neurobiology of Aging , 32 :2320 e15 , 2011 |
| Abstract : |
| PubMedSearch : Darreh-Shori_2011_Neurobiol.Aging_32_2320 e15 |
| PubMedID: 20538374 |
| Title : CSF biomarkers predict a more malignant outcome in Alzheimer disease - Wallin_2010_Neurology_74_1531 |
| Author(s) : Wallin AK , Blennow K , Zetterberg H , Londos E , Minthon L , Hansson O |
| Ref : Neurology , 74 :1531 , 2010 |
| Abstract : |
| PubMedSearch : Wallin_2010_Neurology_74_1531 |
| PubMedID: 20458070 |
| Title : The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer's disease - Wiig_2010_Acta.Neurol.Scand_121_186 |
| Author(s) : Wiig EH , Annas P , Basun H , Andreasen N , Lannfelt L , Zetterberg H , Blennow K , Minthon L |
| Ref : Acta Neurologica Scandinavica , 121 :186 , 2010 |
| Abstract : |
| PubMedSearch : Wiig_2010_Acta.Neurol.Scand_121_186 |
| PubMedID: 19785641 |
| Title : Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study - Degerman_2010_Dement.Geriatr.Cogn.Disord_29_204 |
| Author(s) : Degerman Gunnarsson M , Lindau M , Wall A , Blennow K , Darreh-Shori T , Basu S , Nordberg A , Larsson A , Lannfelt L , Basun H , Kilander L |
| Ref : Dementia & Geriatric Cognitive Disorders , 29 :204 , 2010 |
| Abstract : |
| PubMedSearch : Degerman_2010_Dement.Geriatr.Cogn.Disord_29_204 |
| PubMedID: 20332638 |
| Title : Computerized cognition assessment during acetylcholinesterase inhibitor treatment in Alzheimer's disease - Wesnes_2010_Acta.Neurol.Scand_122_270 |
| Author(s) : Wesnes K , Edgar C , Andreasen N , Annas P , Basun H , Lannfelt L , Zetterberg H , Blennow K , Minthon L |
| Ref : Acta Neurologica Scandinavica , 122 :270 , 2010 |
| Abstract : |
| PubMedSearch : Wesnes_2010_Acta.Neurol.Scand_122_270 |
| PubMedID: 20047570 |
| Title : Can CSF biomarkers or pre-treatment progression rate predict response to cholinesterase inhibitor treatment in Alzheimer's disease? - Wallin_2009_Int.J.Geriatr.Psychiatry_24_638 |
| Author(s) : Wallin AK , Hansson O , Blennow K , Londos E , Minthon L |
| Ref : Int J Geriatr Psychiatry , 24 :638 , 2009 |
| Abstract : |
| PubMedSearch : Wallin_2009_Int.J.Geriatr.Psychiatry_24_638 |
| PubMedID: 19123199 |
| Title : Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial - Lannfelt_2008_Lancet.Neurol_7_779 |
| Author(s) : Lannfelt L , Blennow K , Zetterberg H , Batsman S , Ames D , Harrison J , Masters CL , Targum S , Bush AI , Murdoch R , Wilson J , Ritchie CW |
| Ref : Lancet Neurol , 7 :779 , 2008 |
| Abstract : |
| PubMedSearch : Lannfelt_2008_Lancet.Neurol_7_779 |
| PubMedID: 18672400 |
| Title : Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease - Garcia-Ayllon_2007_J.Neurochem_101_1701 |
| Author(s) : Garcia-Ayllon MS , Silveyra MX , Andreasen N , Brimijoin S , Blennow K , Saez-Valero J |
| Ref : Journal of Neurochemistry , 101 :1701 , 2007 |
| Abstract : |
| PubMedSearch : Garcia-Ayllon_2007_J.Neurochem_101_1701 |
| PubMedID: 17326766 |
| Title : Longitudinal stability of CSF biomarkers in Alzheimer's disease - Blennow_2007_Neurosci.Lett_419_18 |
| Author(s) : Blennow K , Zetterberg H , Minthon L , Lannfelt L , Strid S , Annas P , Basun H , Andreasen N |
| Ref : Neuroscience Letters , 419 :18 , 2007 |
| Abstract : |
| PubMedSearch : Blennow_2007_Neurosci.Lett_419_18 |
| PubMedID: 17482358 |
| Title : Alzheimer's disease - Blennow_2006_Lancet_368_387 |
| Author(s) : Blennow K , de Leon MJ , Zetterberg H |
| Ref : Lancet , 368 :387 , 2006 |
| Abstract : |
| PubMedSearch : Blennow_2006_Lancet_368_387 |
| PubMedID: 16876668 |
| Title : Decreased cerebrospinal fluid acetylcholinesterase in patients with subcortical ischemic vascular dementia - Wallin_2003_Dement.Geriatr.Cogn.Disord_16_200 |
| Author(s) : Wallin A , Sjogren M , Blennow K , Davidsson P |
| Ref : Dementia & Geriatric Cognitive Disorders , 16 :200 , 2003 |
| Abstract : |
| PubMedSearch : Wallin_2003_Dement.Geriatr.Cogn.Disord_16_200 |
| PubMedID: 14512714 |
| Title : Cerebral glucose metabolism, cerebrospinal fluid-beta-amyloid(1-42) (CSF-Abeta42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients - Stefanova_2003_Neurosci.Lett_338_159 |
| Author(s) : Stefanova E , Blennow K , Almkvist O , Hellstrom-Lindahl E , Nordberg A |
| Ref : Neuroscience Letters , 338 :159 , 2003 |
| Abstract : |
| PubMedSearch : Stefanova_2003_Neurosci.Lett_338_159 |
| PubMedID: 12566177 |
| Title : CSF markers for incipient Alzheimer's disease - Blennow_2003_Lancet.Neurol_2_605 |
| Author(s) : Blennow K , Hampel H |
| Ref : Lancet Neurol , 2 :605 , 2003 |
| Abstract : |
| PubMedSearch : Blennow_2003_Lancet.Neurol_2_605 |
| PubMedID: 14505582 |
| Title : Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease - Saez-Valero_2003_J.Neurosci.Res_72_520 |
| Author(s) : Saez-Valero J , Fodero LR , Sjogren M , Andreasen N , Amici S , Gallai V , Vanderstichele H , Vanmechelen E , Parnetti L , Blennow K , Small DH |
| Ref : Journal of Neuroscience Research , 72 :520 , 2003 |
| Abstract : |
| PubMedSearch : Saez-Valero_2003_J.Neurosci.Res_72_520 |
| PubMedID: 12704813 |
| Title : Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors - Parnetti_2002_Neurol.Sci_23_S95 |
| Author(s) : Parnetti L , Amici S , Lanari A , Romani C , Antognelli C , Andreasen N , Minthon L , Davidsson P , Pottel H , Blennow K , Gallai V |
| Ref : Neurol Sci , 23 :S95 , 2002 |
| Abstract : |
| PubMedSearch : Parnetti_2002_Neurol.Sci_23_S95 |
| PubMedID: 12548360 |
| Title : Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease - Davidsson_2001_Neurosci.Lett_300_157 |
| Author(s) : Davidsson P , Blennow K , Andreasen N , Eriksson B , Minthon L , Hesse C |
| Ref : Neuroscience Letters , 300 :157 , 2001 |
| Abstract : |
| PubMedSearch : Davidsson_2001_Neurosci.Lett_300_157 |
| PubMedID: 11226635 |
| Title : Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease - Prince_2001_Eur.J.Hum.Genet_9_437 |
| Author(s) : Prince JA , Feuk L , Sawyer SL , Gottfries J , Ricksten A , Nagga K , Bogdanovic N , Blennow K , Brookes AJ |
| Ref : Eur J Hum Genet , 9 :437 , 2001 |
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| PubMedSearch : Prince_2001_Eur.J.Hum.Genet_9_437 |
| PubMedID: 11436125 |