Full name : Brimijoin Stephen
First name : Stephen
Mail : Mayo Clinic\; Department of Molecular Pharmacology & Experimental Therapeutics\; 200 First Street SW\; Rochester\; MN 55905
Zip Code : 55905
City : Rochester, Minnesota
Country : USA
Email :
Phone :
Fax :
Website : \/\/www.mayo.edu\/research\/faculty\/brimijoin-william-s-ph-d\/BIO-00025901
Directory :
Comment
William Stephen Brimijoin (Steve) was born July 1, 1942 in Passaic New Jersey and died August 13 2024. He earned a Harvard pharmacology PhD in 1969. He joined Julius Axelrod at the National Institute of Health (NIH). Brimijoin invented novel methods to measure intra-neuronal trafficking systems. Brimijoin joined in 1971 the Department of Pharmacology at Mayo Clinic. He discovered a major role for Butyrylcholinesterase: to regulate ghrelin, which drives cravings for food, drink, and addictive drugs like cocaine. His animal studies showed that raising BChE levels with a harmless viral vector would lower ghrelin levels, reduce hunger pangs, restore healthy eating in obesity-prone subjects, reduce cravings for drugs like cocaine, and ease anxiety and stress.
| Title : A plant-derived cocaine hydrolase prevents cocaine overdose lethality and attenuates cocaine-induced drug seeking behavior - Larrimore_2020_Prog.Neuropsychopharmacol.Biol.Psychiatry__109961 |
| Author(s) : Larrimore KE , Kannan L , Kendle RP , Jamal T , Barcus M , Stefanko K , Kilbourne J , Brimijoin S , Zhan CG , Neisewander J , Mor TS |
| Ref : Prog Neuropsychopharmacol Biological Psychiatry , :109961 , 2020 |
| Abstract : |
| PubMedSearch : Larrimore_2020_Prog.Neuropsychopharmacol.Biol.Psychiatry__109961 |
| PubMedID: 32387315 |
| Title : In vivo localization of human acetylcholinesterase-derived species in a beta-sheet conformation at the core of senile plaques in Alzheimer's disease - Jean_2019_J.Biol.Chem_294_6253 |
| Author(s) : Jean L , Brimijoin S , Vaux DJ |
| Ref : Journal of Biological Chemistry , 294 :6253 , 2019 |
| Abstract : |
| PubMedSearch : Jean_2019_J.Biol.Chem_294_6253 |
| PubMedID: 30787102 |
| Title : Author Correction: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity - Larrimore_2018_Sci.Rep_8_17223 |
| Author(s) : Larrimore KE , Kazan IC , Kannan L , Kendle RP , Jamal T , Barcus M , Bolia A , Brimijoin S , Zhan CG , Ozkan SB , Mor TS |
| Ref : Sci Rep , 8 :17223 , 2018 |
| Abstract : |
| PubMedSearch : Larrimore_2018_Sci.Rep_8_17223 |
| PubMedID: 30443038 |
| Title : Favorable Impact on Stress-Related Behaviors by Modulating Plasma Butyrylcholinesterase - Brimijoin_2018_Cell.Mol.Neurobiol_38_7 |
| Author(s) : Brimijoin S , Tye S |
| Ref : Cellular Molecular Neurobiology , 38 :7 , 2018 |
| Abstract : |
| PubMedSearch : Brimijoin_2018_Cell.Mol.Neurobiol_38_7 |
| PubMedID: 28712092 |
| Title : Treating Cocaine Addiction, Obesity, and Emotional Disorders by Viral Gene Transfer of Butyrylcholinesterase - Brimijoin_2018_Front.Pharmacol_9_112 |
| Author(s) : Brimijoin S , Gao Y , Geng L , Chen VP |
| Ref : Front Pharmacol , 9 :112 , 2018 |
| Abstract : |
| PubMedSearch : Brimijoin_2018_Front.Pharmacol_9_112 |
| PubMedID: 29535625 |
| Title : Cholinesterases and the fine line between poison and remedy - Pope_2018_Biochem.Pharmacol_153_205 |
| Author(s) : Pope CN , Brimijoin S |
| Ref : Biochemical Pharmacology , 153 :205 , 2018 |
| Abstract : |
| PubMedSearch : Pope_2018_Biochem.Pharmacol_153_205 |
| PubMedID: 29409903 |
| Title : Therapeutic Delivery of Butyrylcholinesterase by Brain-Wide Viral Gene Transfer to Mice - Gao_2017_Molecules_22_ |
| Author(s) : Gao Y , Geng L , Chen VP , Brimijoin S |
| Ref : Molecules , 22 : , 2017 |
| Abstract : |
| PubMedSearch : Gao_2017_Molecules_22_ |
| PubMedID: 28698452 |
| Title : Polyionic complexes of butyrylcholinesterase and poly-l-lysine-g-poly(ethylene glycol): Comparative kinetics of catalysis and inhibition and in vitro inactivation by proteases and heat - Hester_2017_Chem.Biol.Interact_275_86 |
| Author(s) : Hester K , Liu J , Flynn N , Sultatos LG , Geng L , Brimijoin S , Ramsey JD , Hartson S , Ranjan A , Pope C |
| Ref : Chemico-Biological Interactions , 275 :86 , 2017 |
| Abstract : |
| PubMedSearch : Hester_2017_Chem.Biol.Interact_275_86 |
| PubMedID: 28756151 |
| Title : Butyrylcholinesterase gene transfer in obese mice prevents postdieting body weight rebound by suppressing ghrelin signaling - Chen_2017_Proc.Natl.Acad.Sci.U.S.A_114_10960 |
| Author(s) : Chen VP , Gao Y , Geng L , Brimijoin S |
| Ref : Proc Natl Acad Sci U S A , 114 :10960 , 2017 |
| Abstract : |
| PubMedSearch : Chen_2017_Proc.Natl.Acad.Sci.U.S.A_114_10960 |
| PubMedID: 28973869 |
| Title : Butyrylcholinesterase regulates central ghrelin signaling and has an impact on food intake and glucose homeostasis - Chen_2017_Int.J.Obes.(Lond)_41_1413 |
| Author(s) : Chen VP , Gao Y , Geng L , Brimijoin S |
| Ref : Int J Obes (Lond) , 41 :1413 , 2017 |
| Abstract : |
| PubMedSearch : Chen_2017_Int.J.Obes.(Lond)_41_1413 |
| PubMedID: 28529331 |
| Title : Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity - Larrimore_2017_Sci.Rep_7_10419 |
| Author(s) : Larrimore KE , Kazan IC , Kannan L , Kendle RP , Jamal T , Barcus M , Bolia A , Brimijoin S , Zhan CG , Ozkan SB , Mor TS |
| Ref : Sci Rep , 7 :10419 , 2017 |
| Abstract : |
| PubMedSearch : Larrimore_2017_Sci.Rep_7_10419 |
| PubMedID: 28874829 |
| Title : Cocaine Hydrolase Gene Transfer Demonstrates Cardiac Safety and Efficacy against Cocaine-Induced QT Prolongation in Mice - Murthy_2016_J.Pharmacol.Exp.Ther_356_720 |
| Author(s) : Murthy V , Reyes S , Geng L , Gao Y , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 356 :720 , 2016 |
| Abstract : |
| PubMedSearch : Murthy_2016_J.Pharmacol.Exp.Ther_356_720 |
| PubMedID: 26669428 |
| Title : Long-Term Blockade of Cocaine Self-Administration and Locomotor Activation in Rats by an Adenoviral Vector-Delivered Cocaine Hydrolase - Smethells_2016_J.Pharmacol.Exp.Ther_357_375 |
| Author(s) : Smethells JR , Swalve N , Brimijoin S , Gao Y , Parks RJ , Greer A , Carroll ME |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 357 :375 , 2016 |
| Abstract : |
| PubMedSearch : Smethells_2016_J.Pharmacol.Exp.Ther_357_375 |
| PubMedID: 26968195 |
| Title : Monoclonal Antibodies That Recognize Various Folding States of Pure Human Butyrylcholinesterase Can Immunopurify Butyrylcholinesterase from Human Plasma Stored at Elevated Temperatures - Peng_2016_ACS.Omega_1_1182 |
| Author(s) : Peng H , Blake TA , Johnson RC , Dafferner AJ , Brimijoin S , Lockridge O |
| Ref : ACS Omega , 1 :1182 , 2016 |
| Abstract : |
| PubMedSearch : Peng_2016_ACS.Omega_1_1182 |
| PubMedID: 28058292 |
| Title : Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma - Peng_2016_Chem.Biol.Interact_243_82 |
| Author(s) : Peng H , Brimijoin S , Hrabovska A , Krejci E , Blake TA , Johnson RC , Masson P , Lockridge O |
| Ref : Chemico-Biological Interactions , 243 :82 , 2016 |
| Abstract : |
| PubMedSearch : Peng_2016_Chem.Biol.Interact_243_82 |
| PubMedID: 26585590 |
| Title : Butyrylcholinesterase deficiency promotes adipose tissue growth and hepatic lipid accumulation in male mice on high-fat diet - Chen_2016_Endocrinology__en20161166 |
| Author(s) : Chen VP , Gao Y , Geng L , Stout MB , Jensen MD , Brimijoin S |
| Ref : Endocrinology , :en20161166 , 2016 |
| Abstract : |
| PubMedSearch : Chen_2016_Endocrinology__en20161166 |
| PubMedID: 27300766 |
| Title : Physiological Roles for Butyrylcholinesterase: A BChE-Ghrelin Axis - Brimijoin_2016_Chem.Biol.Interact_259_271 |
| Author(s) : Brimijoin S , Chen VP , Pang YP , Geng L , Gao Y |
| Ref : Chemico-Biological Interactions , 259 :271 , 2016 |
| Abstract : |
| PubMedSearch : Brimijoin_2016_Chem.Biol.Interact_259_271 |
| PubMedID: 26915976 |
| Title : Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase - Chen_2015_Biochem.J_466_243 |
| Author(s) : Chen X , Huang X , Geng L , Xue L , Hou S , Zheng X , Brimijoin S , Zheng F , Zhan CG |
| Ref : Biochemical Journal , 466 :243 , 2015 |
| Abstract : |
| PubMedSearch : Chen_2015_Biochem.J_466_243 |
| PubMedID: 25486543 |
| Gene_locus related to this paper: human-BCHE |
| Title : Plasma butyrylcholinesterase regulates ghrelin to control aggression - Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| Author(s) : Chen VP , Gao Y , Geng L , Parks RJ , Pang YP , Brimijoin S |
| Ref : Proc Natl Acad Sci U S A , 112 :2251 , 2015 |
| Abstract : |
| PubMedSearch : Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| PubMedID: 25646463 |
| Title : Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin - Schopfer_2015_Gen.Comp.Endocrinol_224_61 |
| Author(s) : Schopfer LM , Lockridge O , Brimijoin S |
| Ref : General & Comparative Endocrinology , 224 :61 , 2015 |
| Abstract : |
| PubMedSearch : Schopfer_2015_Gen.Comp.Endocrinol_224_61 |
| PubMedID: 26073531 |
| Title : Radiometric assay of ghrelin hydrolase activity and (3)H-ghrelin distribution into mouse tissues - Chen_2015_Biochem.Pharmacol_98_732 |
| Author(s) : Chen VP , Gao Y , Geng L , Brimijoin S |
| Ref : Biochemical Pharmacology , 98 :732 , 2015 |
| Abstract : |
| PubMedSearch : Chen_2015_Biochem.Pharmacol_98_732 |
| PubMedID: 26514871 |
| Title : Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase - Murthy_2015_Cell.Mol.Neurobiol_35_819 |
| Author(s) : Murthy V , Geng L , Gao Y , Zhang B , Miller JD , Reyes S , Brimijoin S |
| Ref : Cellular Molecular Neurobiology , 35 :819 , 2015 |
| Abstract : |
| PubMedSearch : Murthy_2015_Cell.Mol.Neurobiol_35_819 |
| PubMedID: 25814464 |
| Title : Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: K values, binding pairs, and amino acid sequences - Peng_2015_Chem.Biol.Interact_240_336 |
| Author(s) : Peng H , Brimijoin S , Hrabovska A , Targosova K , Krejci E , Blake TA , Johnson RC , Masson P , Lockridge O |
| Ref : Chemico-Biological Interactions , 240 :336 , 2015 |
| Abstract : |
| PubMedSearch : Peng_2015_Chem.Biol.Interact_240_336 |
| PubMedID: 26343001 |
| Title : In vitro characterization of cationic copolymer-complexed recombinant human butyrylcholinesterase - Pope_2015_Biochem.Pharmacol_98_531 |
| Author(s) : Pope C , Uchea C , Flynn N , Poindexter K , Geng L , Brimijoin S , Hartson S , Ranjan A , Ramsey JD , Liu J |
| Ref : Biochemical Pharmacology , 98 :531 , 2015 |
| Abstract : |
| PubMedSearch : Pope_2015_Biochem.Pharmacol_98_531 |
| PubMedID: 26456723 |
| Title : Long-term reduction of cocaine self-administration in rats treated with adenoviral vector-delivered cocaine hydrolase: evidence for enzymatic activity - Zlebnik_2014_Neuropsychopharmacology_39_1538 |
| Author(s) : Zlebnik NE , Brimijoin S , Gao Y , Saykao AT , Parks RJ , Carroll ME |
| Ref : Neuropsychopharmacology , 39 :1538 , 2014 |
| Abstract : |
| PubMedSearch : Zlebnik_2014_Neuropsychopharmacology_39_1538 |
| PubMedID: 24407266 |
| Title : Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice - Murthy_2014_Vaccine_32_4155 |
| Author(s) : Murthy V , Gao Y , Geng L , LeBrasseur NK , White TA , Parks RJ , Brimijoin S |
| Ref : Vaccine , 32 :4155 , 2014 |
| Abstract : |
| PubMedSearch : Murthy_2014_Vaccine_32_4155 |
| PubMedID: 24892251 |
| Title : Preclinical studies on neurobehavioral and neuromuscular effects of cocaine hydrolase gene therapy in mice - Murthy_2014_J.Mol.Neurosci_53_409 |
| Author(s) : Murthy V , Gao Y , Geng L , LeBrasseur NK , White TA , Brimijoin S |
| Ref : Journal of Molecular Neuroscience , 53 :409 , 2014 |
| Abstract : |
| PubMedSearch : Murthy_2014_J.Mol.Neurosci_53_409 |
| PubMedID: 24085526 |
| Title : The future potential for cocaine vaccines - Orson_2014_Expert.Opin.Biol.Ther_14_1271 |
| Author(s) : Orson FM , Wang R , Brimijoin S , Kinsey BM , Singh RA , Ramakrishnan M , Wang HY , Kosten TR |
| Ref : Expert Opin Biol Ther , 14 :1271 , 2014 |
| Abstract : |
| PubMedSearch : Orson_2014_Expert.Opin.Biol.Ther_14_1271 |
| PubMedID: 24835496 |
| Title : Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage - Gao_2013_Chem.Biol.Interact_203_208 |
| Author(s) : Gao Y , Geng L , Orson FM , Kinsey B , Kosten TR , Shen X , Brimijoin S |
| Ref : Chemico-Biological Interactions , 203 :208 , 2013 |
| Abstract : |
| PubMedSearch : Gao_2013_Chem.Biol.Interact_203_208 |
| PubMedID: 22935511 |
| Title : Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice - Brimijoin_2013_Chem.Biol.Interact_203_212 |
| Author(s) : Brimijoin S , Orson FM , Kosten TR , Kinsey B , Shen XY , White SJ , Gao Y |
| Ref : Chemico-Biological Interactions , 203 :212 , 2013 |
| Abstract : |
| PubMedSearch : Brimijoin_2013_Chem.Biol.Interact_203_212 |
| PubMedID: 22960160 |
| Title : Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity - Larrimore_2013_Chem.Biol.Interact_203_217 |
| Author(s) : Larrimore KE , Barcus M , Kannan L , Gao Y , Zhan CG , Brimijoin S , Mor TS |
| Ref : Chemico-Biological Interactions , 203 :217 , 2013 |
| Abstract : |
| PubMedSearch : Larrimore_2013_Chem.Biol.Interact_203_217 |
| PubMedID: 23000451 |
| Title : Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides - Pang_2012_Curr.Drug.Targets_13_471 |
| Author(s) : Pang YP , Brimijoin S , Ragsdale DW , Zhu KY , Suranyi R |
| Ref : Curr Drug Targets , 13 :471 , 2012 |
| Abstract : |
| PubMedSearch : Pang_2012_Curr.Drug.Targets_13_471 |
| PubMedID: 22280344 |
| Gene_locus related to this paper: aphgo-ACHE1 |
| Title : Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months - Anker_2012_Biol.Psychiatry_71_700 |
| Author(s) : Anker JJ , Brimijoin S , Gao Y , Geng L , Zlebnik NE , Parks RJ , Carroll ME |
| Ref : Biological Psychiatry , 71 :700 , 2012 |
| Abstract : |
| PubMedSearch : Anker_2012_Biol.Psychiatry_71_700 |
| PubMedID: 22209637 |
| Title : Cocaine hydrolase gene therapy for cocaine abuse - Brimijoin_2012_Future.Med.Chem_4_151 |
| Author(s) : Brimijoin S , Gao Y |
| Ref : Future Med Chem , 4 :151 , 2012 |
| Abstract : |
| PubMedSearch : Brimijoin_2012_Future.Med.Chem_4_151 |
| PubMedID: 22300095 |
| Title : Combined cocaine hydrolase gene transfer and anti-cocaine vaccine synergistically block cocaine-induced locomotion - Carroll_2012_PLoS.One_7_e43536 |
| Author(s) : Carroll ME , Zlebnik NE , Anker JJ , Kosten TR , Orson FM , Shen X , Kinsey B , Parks RJ , Gao Y , Brimijoin S |
| Ref : PLoS ONE , 7 :e43536 , 2012 |
| Abstract : |
| PubMedSearch : Carroll_2012_PLoS.One_7_e43536 |
| PubMedID: 22912888 |
| Title : Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats - Carroll_2011_Psychopharmacology.(Berl)_213_817 |
| Author(s) : Carroll ME , Gao Y , Brimijoin S , Anker JJ |
| Ref : Psychopharmacology (Berl) , 213 :817 , 2011 |
| Abstract : |
| PubMedSearch : Carroll_2011_Psychopharmacology.(Berl)_213_817 |
| PubMedID: 20972552 |
| Title : Interception of cocaine by enzyme or antibody delivered with viral gene transfer: a novel strategy for preventing relapse in recovering drug users - Brimijoin_2011_CNS.Neurol.Disord.Drug.Targets_10_880 |
| Author(s) : Brimijoin S |
| Ref : CNS Neurol Disord Drug Targets , 10 :880 , 2011 |
| Abstract : |
| PubMedSearch : Brimijoin_2011_CNS.Neurol.Disord.Drug.Targets_10_880 |
| PubMedID: 22229308 |
| Title : The concept of pharmacologic cocaine interception as a treatment for drug abuse - Gao_2010_Chem.Biol.Interact_187_421 |
| Author(s) : Gao Y , Orson FM , Kinsey B , Kosten T , Brimijoin S |
| Ref : Chemico-Biological Interactions , 187 :421 , 2010 |
| Abstract : |
| PubMedSearch : Gao_2010_Chem.Biol.Interact_187_421 |
| PubMedID: 20219449 |
| Title : Insect-specific irreversible inhibitors of acetylcholinesterase in pests including the bed bug, the eastern yellowjacket, German and American cockroaches, and the confused flour beetle - Polsinelli_2010_Chem.Biol.Interact_187_142 |
| Author(s) : Polsinelli GA , Singh SK , Mishra RK , Suranyi R , Ragsdale DW , Pang YP , Brimijoin S |
| Ref : Chemico-Biological Interactions , 187 :142 , 2010 |
| Abstract : |
| PubMedSearch : Polsinelli_2010_Chem.Biol.Interact_187_142 |
| PubMedID: 20109441 |
| Title : Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases - Pang_2009_PLoS.One_4_e6851 |
| Author(s) : Pang YP , Ekstrom F , Polsinelli GA , Gao Y , Rana S , Hua DH , Andersson B , Andersson PO , Peng L , Singh SK , Mishra RK , Zhu KY , Fallon AM , Ragsdale DW , Brimijoin S |
| Ref : PLoS ONE , 4 :e6851 , 2009 |
| Abstract : |
| PubMedSearch : Pang_2009_PLoS.One_4_e6851 |
| PubMedID: 19714254 |
| Gene_locus related to this paper: mouse-ACHE , mouse-acnt1 |
| Title : Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides - Pang_2009_PLoS.ONE_4_e4349 |
| Author(s) : Pang YP , Singh SK , Gao Y , Lassiter TL , Mishra RK , Zhu KY , Brimijoin S |
| Ref : PLoS ONE , 4 :e4349 , 2009 |
| Abstract : |
| PubMedSearch : Pang_2009_PLoS.ONE_4_e4349 |
| PubMedID: 19194505 |
| Title : Cholinesterase inhibition and acetylcholine accumulation following intracerebral administration of paraoxon in rats - Ray_2009_Toxicol.Appl.Pharmacol_236_341 |
| Author(s) : Ray A , Liu J , Karanth S , Gao Y , Brimijoin S , Pope C |
| Ref : Toxicol Appl Pharmacol , 236 :341 , 2009 |
| Abstract : |
| PubMedSearch : Ray_2009_Toxicol.Appl.Pharmacol_236_341 |
| PubMedID: 19272400 |
| Title : Lasting reduction of cocaine action in neostriatum--a hydrolase gene therapy approach - Gao_2009_J.Pharmacol.Exp.Ther_330_449 |
| Author(s) : Gao Y , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :449 , 2009 |
| Abstract : |
| PubMedSearch : Gao_2009_J.Pharmacol.Exp.Ther_330_449 |
| PubMedID: 19478136 |
| Title : An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties - Gao_2008_Chem.Biol.Interact_175_83 |
| Author(s) : Gao Y , Lafleur D , Shah R , Zhao Q , Singh M , Brimijoin S |
| Ref : Chemico-Biological Interactions , 175 :83 , 2008 |
| Abstract : |
| PubMedSearch : Gao_2008_Chem.Biol.Interact_175_83 |
| PubMedID: 18514640 |
| Title : A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats - Brimijoin_2008_Neuropsychopharmacology_33_2715 |
| Author(s) : Brimijoin S , Gao Y , Anker JJ , Gliddon LA , Lafleur D , Shah R , Zhao Q , Singh M , Carroll ME |
| Ref : Neuropsychopharmacology , 33 :2715 , 2008 |
| Abstract : |
| PubMedSearch : Brimijoin_2008_Neuropsychopharmacology_33_2715 |
| PubMedID: 18199998 |
| Title : Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease - Garcia-Ayllon_2007_J.Neurochem_101_1701 |
| Author(s) : Garcia-Ayllon MS , Silveyra MX , Andreasen N , Brimijoin S , Blennow K , Saez-Valero J |
| Ref : Journal of Neurochemistry , 101 :1701 , 2007 |
| Abstract : |
| PubMedSearch : Garcia-Ayllon_2007_J.Neurochem_101_1701 |
| PubMedID: 17326766 |
| Title : A method to determine precise benchmark doses for carbamate anticholinesterases - Lassiter_2007_Toxicol.Sci_96_154 |
| Author(s) : Lassiter TL , Brimijoin S |
| Ref : Toxicol Sci , 96 :154 , 2007 |
| Abstract : |
| PubMedSearch : Lassiter_2007_Toxicol.Sci_96_154 |
| PubMedID: 17159234 |
| Title : Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE epsilon4 allele, in relation to cognitive function and cerebral glucose metabolism - Darreh-Shori_2006_Neurobiol.Dis_24_326 |
| Author(s) : Darreh-Shori T , Brimijoin S , Kadir A , Almkvist O , Nordberg A |
| Ref : Neurobiol Dis , 24 :326 , 2006 |
| Abstract : |
| PubMedSearch : Darreh-Shori_2006_Neurobiol.Dis_24_326 |
| PubMedID: 16973370 |
| Title : Viral transduction of cocaine hydrolase in brain reward centers - Gao_2006_Cell.Mol.Neurobiol_26_357 |
| Author(s) : Gao Y , Brimijoin S |
| Ref : Cellular Molecular Neurobiology , 26 :357 , 2006 |
| Abstract : |
| PubMedSearch : Gao_2006_Cell.Mol.Neurobiol_26_357 |
| PubMedID: 16708286 |
| Title : Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats - Gao_2005_Mol.Pharmacol_67_204 |
| Author(s) : Gao Y , Atanasova E , Sui N , Pancook JD , Watkins JD , Brimijoin S |
| Ref : Molecular Pharmacology , 67 :204 , 2005 |
| Abstract : |
| PubMedSearch : Gao_2005_Mol.Pharmacol_67_204 |
| PubMedID: 15465921 |
| Title : Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats - Gao_2005_Chem.Biol.Interact_157-158_97 |
| Author(s) : Gao Y , Brimijoin S |
| Ref : Chemico-Biological Interactions , 157-158 :97 , 2005 |
| Abstract : |
| PubMedSearch : Gao_2005_Chem.Biol.Interact_157-158_97 |
| PubMedID: 16243302 |
| Title : Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice - Rees_2005_Curr.Alzheimer.Res_2_291 |
| Author(s) : Rees TM , Berson A , Sklan EH , Younkin L , Younkin S , Brimijoin S , Soreq H |
| Ref : Curr Alzheimer Res , 2 :291 , 2005 |
| Abstract : |
| PubMedSearch : Rees_2005_Curr.Alzheimer.Res_2_291 |
| PubMedID: 15974894 |
| Title : Mechanisms underlying the axonal growth promoting property of acetylcholinesterase - |
| Author(s) : Bigbee JW , Sharma KV , Koenigsberger C , Brimijoin S |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :295 , 2004 |
| PubMedID: |
| Title : Poster (45) Mechanisms underlying the morphogenic properties of acetylcholinesterase - |
| Author(s) : Bigbee JW , Sharma KV , Koenigsberger C , Brimijoin S |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :344 , 2004 |
| PubMedID: |
| Title : An engineered cocaine hydrolase blunts and reverses cardiovascular responses to cocaine in rats - Gao_2004_J.Pharmacol.Exp.Ther_310_1046 |
| Author(s) : Gao Y , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :1046 , 2004 |
| Abstract : |
| PubMedSearch : Gao_2004_J.Pharmacol.Exp.Ther_310_1046 |
| PubMedID: 15100387 |
| Title : Poster (58) Acetylcholinesterase promotes amyloid plaques in transgenic mouse brain. - |
| Author(s) : Brimijoin S , Rees TM , Soreq H , Younkin S |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :352 , 2004 |
| PubMedID: |
| Title : Acetylcholinesterase expression and the formation of amyloid plaques in a transgenic mouse model of Alzheimer's disease - |
| Author(s) : Brimijoin S , Rees TM |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :115 , 2004 |
| PubMedID: |
| Title : Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex - Rees_2003_Neurobiol.Aging_24_777 |
| Author(s) : Rees TM , Hammond PI , Soreq H , Younkin S , Brimijoin S |
| Ref : Neurobiology of Aging , 24 :777 , 2003 |
| Abstract : |
| PubMedSearch : Rees_2003_Neurobiol.Aging_24_777 |
| PubMedID: 12927760 |
| Title : Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators - Pang_2003_Chem.Biol_10_491 |
| Author(s) : Pang YP , Kollmeyer TM , Hong F , Lee JC , Hammond PI , Haugabouk SP , Brimijoin S |
| Ref : Chemical Biology , 10 :491 , 2003 |
| Abstract : |
| PubMedSearch : Pang_2003_Chem.Biol_10_491 |
| PubMedID: 12837382 |
| Title : The role of acetylcholinesterase in the pathogenesis of Alzheimer's disease - Rees_2003_Drugs.Today.(Barc)_39_75 |
| Author(s) : Rees TM , Brimijoin S |
| Ref : Drugs Today (Barc) , 39 :75 , 2003 |
| Abstract : |
| PubMedSearch : Rees_2003_Drugs.Today.(Barc)_39_75 |
| PubMedID: 12669110 |
| Title : Cholinesterase reactivation in vivo with a novel bis-oxime optimized by computer-aided design - Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| Author(s) : Hammond PI , Kern C , Hong F , Kollmeyer TM , Pang YP , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 307 :190 , 2003 |
| Abstract : |
| PubMedSearch : Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| PubMedID: 12893843 |
| Title : Apoptosis induced by beta-amyloid25-35 in acetylcholinesterase-overexpressing neuroblastoma cells - Zhang_2003_Acta.Pharmacol.Sin_24_853 |
| Author(s) : Zhang HY , Brimijoin S , Tang XC |
| Ref : Acta Pharmacol Sin , 24 :853 , 2003 |
| Abstract : |
| PubMedSearch : Zhang_2003_Acta.Pharmacol.Sin_24_853 |
| PubMedID: 12956931 |
| Title : Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation - Hu_2003_J.Neurochem_86_470 |
| Author(s) : Hu W , Gray NW , Brimijoin S |
| Ref : Journal of Neurochemistry , 86 :470 , 2003 |
| Abstract : |
| PubMedSearch : Hu_2003_J.Neurochem_86_470 |
| PubMedID: 12871588 |
| Title : Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase - Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| Author(s) : Sun H , Shen ML , Pang YP , Lockridge O , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :710 , 2002 |
| Abstract : |
| PubMedSearch : Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| PubMedID: 12130735 |
| Gene_locus related to this paper: human-BCHE |
| Title : Re-engineering butyrylcholinesterase as a cocaine hydrolase - Sun_2002_Mol.Pharmacol_62_220 |
| Author(s) : Sun H , Pang YP , Lockridge O , Brimijoin S |
| Ref : Molecular Pharmacology , 62 :220 , 2002 |
| Abstract : |
| PubMedSearch : Sun_2002_Mol.Pharmacol_62_220 |
| PubMedID: 12130672 |
| Gene_locus related to this paper: human-BCHE |
| Title : Death of preganglionic sympathetic neurons after surgical or immunologic lesion of peripheral processes - Tang_2002_Exp.Neurol_177_105 |
| Author(s) : Tang H , Brimijoin S |
| Ref : Experimental Neurology , 177 :105 , 2002 |
| Abstract : |
| PubMedSearch : Tang_2002_Exp.Neurol_177_105 |
| PubMedID: 12429215 |
| Title : Direct evidence for an adhesive function in the noncholinergic role of acetylcholinesterase in neurite outgrowth - Sharma_2001_J.Neurosci.Res_63_165 |
| Author(s) : Sharma KV , Koenigsberger C , Brimijoin S , Bigbee JW |
| Ref : Journal of Neuroscience Research , 63 :165 , 2001 |
| Abstract : |
| PubMedSearch : Sharma_2001_J.Neurosci.Res_63_165 |
| PubMedID: 11169626 |
| Title : Complement regulatory proteins and selective vulnerability of neurons to lysis on exposure to acetylcholinesterase antibody - Tang_2001_J.Neuroimmunol_115_53 |
| Author(s) : Tang H , Brimijoin S |
| Ref : Journal of Neuroimmunology , 115 :53 , 2001 |
| Abstract : |
| PubMedSearch : Tang_2001_J.Neuroimmunol_115_53 |
| PubMedID: 11282154 |
| Title : Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. - Sun_2001_J.Biol.Chem_276_9330 |
| Author(s) : Sun H , El Yazal J , Lockridge O , Schopfer LM , Brimijoin S , Pang YP |
| Ref : Journal of Biological Chemistry , 276 :9330 , 2001 |
| Abstract : |
| PubMedSearch : Sun_2001_J.Biol.Chem_276_9330 |
| PubMedID: 11104759 |
| Title : Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse - Li_2000_J.Neurochem_75_1320 |
| Author(s) : Li B , Stribley JA , Ticu A , Xie W , Schopfer LM , Hammond P , Brimijoin S , Hinrichs SH , Lockridge O |
| Ref : Journal of Neurochemistry , 75 :1320 , 2000 |
| Abstract : |
| PubMedSearch : Li_2000_J.Neurochem_75_1320 |
| PubMedID: 10936216 |
| Title : Cholinesterases in Neural Development: New Findings and Toxicologic Implications - Brimijoin_1999_Environ.Health.Perspect_1_59 |
| Author(s) : Brimijoin S , Koenigsberger C |
| Ref : Environmental Health Perspectives , 1 :59 , 1999 |
| Abstract : |
| PubMedSearch : Brimijoin_1999_Environ.Health.Perspect_1_59 |
| PubMedID: 10229707 |
| Title : Complement-mediated lesion of sympathetic ganglia in vitro with acetylcholinesterase antibodies - Tang_1999_J.Neuroimmunol_97_86 |
| Author(s) : Tang H , Miller SM , Ermilov LG , Lennon VA , Brimijoin S |
| Ref : Journal of Neuroimmunology , 97 :86 , 1999 |
| Abstract : |
| PubMedSearch : Tang_1999_J.Neuroimmunol_97_86 |
| PubMedID: 10408983 |
| Title : Novel messenger RNA and alternative promoter for murine acetylcholinesterase - Atanasova_1999_J.Biol.Chem_274_21078 |
| Author(s) : Atanasova E , Chiappa S , Wieben E , Brimijoin S |
| Ref : Journal of Biological Chemistry , 274 :21078 , 1999 |
| Abstract : |
| PubMedSearch : Atanasova_1999_J.Biol.Chem_274_21078 |
| PubMedID: 10409660 |
| Title : Developmental expression of acetyl- and butyrylcholinesterase in the rat: enzyme and mRNA levels in embryonic dorsal root ganglia - Koenigsberger_1998_Brain.Res_787_248 |
| Author(s) : Koenigsberger C , Hammond P , Brimijoin S |
| Ref : Brain Research , 787 :248 , 1998 |
| Abstract : |
| PubMedSearch : Koenigsberger_1998_Brain.Res_787_248 |
| PubMedID: 9518638 |
| Title : Pharmacologic Tests of a Role for Acetylcholinesterase in Promoting Neurite Outgrowth by Dorsal Root Ganglia - |
| Author(s) : Chiappa S , Brimijoin S |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :585 , 1998 |
| PubMedID: |
| Title : Improved Acetylcholinesterase Reactivation with Bis-Oximes Modeled on Crystal Structure - |
| Author(s) : Hammond P , Kern C , Pang YP , Brimijoin S |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :252 , 1998 |
| PubMedID: |
| Title : Comparison of the in vitro sensitivity of rat acetylcholinesterase to chlorpyrifos-oxon: what do tissue IC50 values represent? - Mortensen_1998_Toxicol.Appl.Pharmacol_148_46 |
| Author(s) : Mortensen SR , Brimijoin S , Hooper MJ , Padilla S |
| Ref : Toxicol Appl Pharmacol , 148 :46 , 1998 |
| Abstract : |
| PubMedSearch : Mortensen_1998_Toxicol.Appl.Pharmacol_148_46 |
| PubMedID: 9465262 |
| Title : Acetylcholinesterase immunolesioning: regional vulnerability of preganglionic sympathetic neurons in rat spinal cord - Tang_1998_Exp.Neurol_152_167 |
| Author(s) : Tang H , Hammond P , Brimijoin S |
| Ref : Experimental Neurology , 152 :167 , 1998 |
| Abstract : |
| PubMedSearch : Tang_1998_Exp.Neurol_152_167 |
| PubMedID: 9710515 |
| Title : Novel Transcription Start Site for Murine AChE - |
| Author(s) : Atanasova E , Brimijoin S |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :112 , 1998 |
| PubMedID: |
| Title : Pharmacologic tests of a role for acetylcholinesterase in promoting neurite outgrowth by dorsal root ganglia - |
| Author(s) : Chiappa S , Brimijoin S |
| Ref : In Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :585 , 1998 |
| PubMedID: |
| Title : Acetylcholinesterase Autoimmunity In Vitro - |
| Author(s) : Tang H , Hammond P , Ermilov L , Miller S , Brimijoin S |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :149 , 1998 |
| PubMedID: |
| Title : Neurite differentiation is modulated in neuroblastoma cells engineered for altered acetylcholinesterase expression - Koenigsberger_1997_J.Neurochem_69_1389 |
| Author(s) : Koenigsberger C , Chiappa S , Brimijoin S |
| Ref : Journal of Neurochemistry , 69 :1389 , 1997 |
| Abstract : |
| PubMedSearch : Koenigsberger_1997_J.Neurochem_69_1389 |
| PubMedID: 9326267 |
| Title : Selective disrpution of neurotransmission by acetylcholinesterase antibodies in sympathetic ganglia examined with intracellular microelectrodes - Miller_1997_J.Auton.Nerv.Syst_67_156 |
| Author(s) : Miller SM , Ermilov LG , Szurszewkski JH , Hammond PI , Brimijoin S |
| Ref : J Auton Nerv Syst , 67 :156 , 1997 |
| Abstract : |
| PubMedSearch : Miller_1997_J.Auton.Nerv.Syst_67_156 |
| PubMedID: 9479667 |
| Title : Lowered norepinephrine turnover as a sign of impaired ganglionic transmission after preganglionic lesioning by acetylcholinesterase antibodies - McKinzie_1996_J.Pharmacol.Exp.Ther_277_817 |
| Author(s) : McKinzie S , Tyce GM , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 277 :817 , 1996 |
| Abstract : |
| PubMedSearch : McKinzie_1996_J.Pharmacol.Exp.Ther_277_817 |
| PubMedID: 8627563 |
| Title : Transient expression of acetylcholinesterase messenger RNA and enzyme activity in developing rat thalamus studied by quantitative histochemistry and in situ hybridization - Brimijoin_1996_Neurosci_71_555 |
| Author(s) : Brimijoin S , Hammond P |
| Ref : Neuroscience , 71 :555 , 1996 |
| Abstract : |
| PubMedSearch : Brimijoin_1996_Neurosci_71_555 |
| PubMedID: 9053807 |
| Title : Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease - Pang_1996_J.Biol.Chem_271_23646 |
| Author(s) : Pang YP , Quiram P , Jelacic T , Hong F , Brimijoin S |
| Ref : Journal of Biological Chemistry , 271 :23646 , 1996 |
| Abstract : |
| PubMedSearch : Pang_1996_J.Biol.Chem_271_23646 |
| PubMedID: 8798583 |
| Title : PACAP in the adrenal gland--relationship with choline acetyltransferase, enkephalin and chromaffin cells and effects of immunological sympathectomy - Holgert_1996_Neuroreport_8_297 |
| Author(s) : Holgert H , Holmberg K , Hannibal J , Fahrenkrug J , Brimijoin S , Hartman BK , Hokfelt T |
| Ref : Neuroreport , 8 :297 , 1996 |
| Abstract : |
| PubMedSearch : Holgert_1996_Neuroreport_8_297 |
| PubMedID: 9051799 |
| Title : Factors in standardizing automated cholinesterase assays - Wilson_1996_J.Toxicol.Environ.Health_48_187 |
| Author(s) : Wilson BW , Padilla S , Henderson JD , Brimijoin S , Dass PD , Elliot G , Jaeger B , Lanz D , Pearson R , Spies R |
| Ref : J Toxicol Environ Health , 48 :187 , 1996 |
| Abstract : |
| PubMedSearch : Wilson_1996_J.Toxicol.Environ.Health_48_187 |
| PubMedID: 8642625 |
| Title : Quantitative, video-based histochemistry to measure regional effects of anticholinesterase pesticides in rat brain - Hammond_1996_Anal.Biochem_241_82 |
| Author(s) : Hammond PI , Jelacic T , Padilla S , Brimijoin S |
| Ref : Analytical Biochemistry , 241 :82 , 1996 |
| Abstract : |
| PubMedSearch : Hammond_1996_Anal.Biochem_241_82 |
| PubMedID: 8921169 |
| Title : Accumulation of enkephalin, proenkephalin mRNA, and neuropeptide Y in immunologically denervated rat adrenal glands: evidence for divergent peptide regulation - Brimijoin_1995_J.Neurochem_64_1281 |
| Author(s) : Brimijoin S , Dagerlind A , Rao R , McKinzie S , Hammond P |
| Ref : Journal of Neurochemistry , 64 :1281 , 1995 |
| Abstract : |
| PubMedSearch : Brimijoin_1995_J.Neurochem_64_1281 |
| PubMedID: 7861161 |
| Title : Slow accumulation of acetylcholinesterase in rat brain during enzyme inhibition by repeated dosing with chlorpyrifos - Chiappa_1995_Biochem.Pharmacol_49_955 |
| Author(s) : Chiappa S , Padilla S , Koenigsberger C , Moser V , Brimijoin S |
| Ref : Biochemical Pharmacology , 49 :955 , 1995 |
| Abstract : |
| PubMedSearch : Chiappa_1995_Biochem.Pharmacol_49_955 |
| PubMedID: 7537966 |
| Title : Reverse transcriptase-polymerase chain reaction assay for acetylcholinesterase mRNA in rat brain - Rao_1995_Neurochem.Res_20_129 |
| Author(s) : Rao R , Brimijoin S |
| Ref : Neurochemical Research , 20 :129 , 1995 |
| Abstract : |
| PubMedSearch : Rao_1995_Neurochem.Res_20_129 |
| PubMedID: 7540259 |
| Title : The cholinergic innervation of the adrenal gland and its relation to enkephalin and nitric oxide synthase - Holgert_1995_Neuroreport_6_2576 |
| Author(s) : Holgert H , Aman K , Cozzari C , Hartman BK , Brimijoin S , Emson P , Goldstein M , Hokfelt T |
| Ref : Neuroreport , 6 :2576 , 1995 |
| Abstract : |
| PubMedSearch : Holgert_1995_Neuroreport_6_2576 |
| PubMedID: 8741766 |
| Title : Mechanism and Implications of Selective Neural Lesions by Acetylcholinesterase Antibodies in the Central and Peripheral Nervous Systems - |
| Author(s) : Brimijoin S , Hammond P , Rakonczay Z |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :247 , 1995 |
| PubMedID: |
| Title : Repeated Dosing with Chlorpyrifos Increases Acetylcholinesterase Immunoreactivity in Rat Brain - |
| Author(s) : Padilla S , Chiappa S , Koenigsberger C , Moser V , Brimijoin S |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :337 , 1995 |
| PubMedID: |
| Title : Regional variation in expression of acetylcholinesterase mRNA in adult rat brain analyzed by in situ hybridization - Hammond_1994_Proc.Natl.Acad.Sci.U.S.A_91_10933 |
| Author(s) : Hammond P , Rao R , Koenigsberger C , Brimijoin S |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 91 :10933 , 1994 |
| Abstract : |
| PubMedSearch : Hammond_1994_Proc.Natl.Acad.Sci.U.S.A_91_10933 |
| PubMedID: 7971986 |
| Title : Catecholamine release and excretion in rats with immunologically induced preganglionic sympathectomy - Brimijoin_1994_J.Neurochem_62_2195 |
| Author(s) : Brimijoin S , Hammond P , Khraibi AA , Tyce GM |
| Ref : Journal of Neurochemistry , 62 :2195 , 1994 |
| Abstract : |
| PubMedSearch : Brimijoin_1994_J.Neurochem_62_2195 |
| PubMedID: 8189228 |
| Title : Effects of preganglionic sympathectomy on peptides in the rat superior cervical ganglion - Dagerlind_1994_Neuroreport_5_909 |
| Author(s) : Dagerlind A , Zhang X , Brimijoin S , Lindh B , Hokfelt T |
| Ref : Neuroreport , 5 :909 , 1994 |
| Abstract : |
| PubMedSearch : Dagerlind_1994_Neuroreport_5_909 |
| PubMedID: 8061294 |
| Title : Neurofibrillary tangles have no obligatory predilection for acetylcholinesterase-rich neurons - Mesulam_1994_Neurobiol.Aging_15_615 |
| Author(s) : Mesulam MM , Brimijoin S , Geula C |
| Ref : Neurobiology of Aging , 15 :615 , 1994 |
| Abstract : |
| PubMedSearch : Mesulam_1994_Neurobiol.Aging_15_615 |
| PubMedID: 7824053 |
| Title : Immunologically induced sympathectomy of preganglionic nerves by antibodies against acetylcholinesterase: increased levels of peptides and their messenger RNAs in rat adrenal chromaffin cells [published erratum appears in Neuroscience 1994 Nov\;63(1):349] - Dagerlind_1994_Neurosci_62_217 |
| Author(s) : Dagerlind A , Pelto-Huikko M , Lundberg JM , Ubink R , Verhofstad A , Brimijoin S , Hokfelt T |
| Ref : Neuroscience , 62 :217 , 1994 |
| Abstract : |
| PubMedSearch : Dagerlind_1994_Neurosci_62_217 |
| PubMedID: 7816201 |
| Title : Lesion of central cholinergic systems by systemically administered acetylcholinesterase antibodies in newborn rats - Rakonczay_1993_Neurosci_54_225 |
| Author(s) : Rakonczay Z , Hammond P , Brimijoin S |
| Ref : Neuroscience , 54 :225 , 1993 |
| Abstract : |
| PubMedSearch : Rakonczay_1993_Neurosci_54_225 |
| PubMedID: 8515843 |
| Title : Effects of antibodies against acetylcholinesterase on the expression of peptides and catecholamine synthesizing enzymes in the rat adrenal gland - Dagerlind_1993_Neurosci_54_1079 |
| Author(s) : Dagerlind A , Brimijoin S , Goldstein M , Hokfelt T |
| Ref : Neuroscience , 54 :1079 , 1993 |
| Abstract : |
| PubMedSearch : Dagerlind_1993_Neurosci_54_1079 |
| PubMedID: 8101982 |
| Title : Death of intermediolateral spinal cord neurons follows selective, complement-mediated destruction of peripheral preganglionic sympathetic terminals by acetylcholinesterase antibodies - Brimijoin_1993_Neurosci_54_201 |
| Author(s) : Brimijoin S , Moser V , Hammond P , Oka N , Lennon VA |
| Ref : Neuroscience , 54 :201 , 1993 |
| Abstract : |
| PubMedSearch : Brimijoin_1993_Neurosci_54_201 |
| PubMedID: 8515842 |
| Title : Experimental Acetylcholinesterase Autoimmunity - |
| Author(s) : Brimijoin S , Lennon VA |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :261 , 1992 |
| PubMedID: |
| Title : Paraoxon toxicity is not potentiated by prior reduction in blood acetylcholinesterase - Padilla_1992_Toxicol.Appl.Pharmacol_117_110 |
| Author(s) : Padilla S , Moser VC , Pope CN , Brimijoin S |
| Ref : Toxicol Appl Pharmacol , 117 :110 , 1992 |
| Abstract : |
| PubMedSearch : Padilla_1992_Toxicol.Appl.Pharmacol_117_110 |
| PubMedID: 1440604 |
| Title : Immunocytochemical demonstration of axonal and perikaryal acetylcholinesterase in human cerebral cortex - Mesulam_1991_Brain.Res_539_233 |
| Author(s) : Mesulam MM , Geula C , Cosgrove R , Mash D , Brimijoin S |
| Ref : Brain Research , 539 :233 , 1991 |
| Abstract : |
| PubMedSearch : Mesulam_1991_Brain.Res_539_233 |
| PubMedID: 2054599 |
| Title : Effect of intracerebral injection of monoclonal acetylcholinesterase antibodies on cholinergic nerve terminals in the rat central nervous system - Bean_1991_Neurosci.Lett_133_145 |
| Author(s) : Bean AJ , Xu Z , Chai SY , Brimijoin S , Hokfelt T |
| Ref : Neuroscience Letters , 133 :145 , 1991 |
| Abstract : |
| PubMedSearch : Bean_1991_Neurosci.Lett_133_145 |
| PubMedID: 1686480 |
| Title : Selective destruction of preganglionic sympathetic nerves by antibodies to acetylcholinesterase. - Brimijoin_1991_J.Neural.Transm.Suppl_34_139 |
| Author(s) : Brimijoin S , Lennon VA |
| Ref : J Neural Transm Suppl , 34 :139 , 1991 |
| Abstract : |
| PubMedSearch : Brimijoin_1991_J.Neural.Transm.Suppl_34_139 |
| PubMedID: 1817157 |
| Title : Experimental Autoimmunity to Neural Acetylcholinesterase - |
| Author(s) : Brimijoin S , Hammond P , Balm M , Lennon VA |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :332 , 1991 |
| PubMedID: |
| Title : Selective complexing of acetylcholinesterase in brain by intravenously administered monoclonal antibody - Brimijoin_1990_J.Neurochem_54_236 |
| Author(s) : Brimijoin S , Balm M , Hammond P , Lennon VA |
| Ref : Journal of Neurochemistry , 54 :236 , 1990 |
| Abstract : |
| PubMedSearch : Brimijoin_1990_J.Neurochem_54_236 |
| PubMedID: 2293614 |
| Title : Autoimmune preganglionic sympathectomy induced by acetylcholinesterase antibodies - Brimijoin_1990_Proc.Natl.Acad.Sci.U.S.A_87_9630 |
| Author(s) : Brimijoin S , Lennon VA |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 87 :9630 , 1990 |
| Abstract : |
| PubMedSearch : Brimijoin_1990_Proc.Natl.Acad.Sci.U.S.A_87_9630 |
| PubMedID: 2175909 |
| Title : Acetylcholinesterase in Huntington's and Alzheimer's diseases: simultaneous enzyme assay and immunoassay of multiple brain regions - Hammond_1988_J.Neurochem_50_1111 |
| Author(s) : Hammond P , Brimijoin S |
| Ref : Journal of Neurochemistry , 50 :1111 , 1988 |
| Abstract : |
| PubMedSearch : Hammond_1988_J.Neurochem_50_1111 |
| PubMedID: 2964509 |
| Title : Monoclonal antibodies to human brain acetylcholinesterase: properties and applications - Rakonczay_1988_Cell.Mol.Neurobiol_8_85 |
| Author(s) : Rakonczay Z , Brimijoin S |
| Ref : Cellular Molecular Neurobiology , 8 :85 , 1988 |
| Abstract : |
| PubMedSearch : Rakonczay_1988_Cell.Mol.Neurobiol_8_85 |
| PubMedID: 3401901 |
| Title : Biochemistry and pathophysiology of the molecular forms of cholinesterases. - |
| Author(s) : Rakonczay Z , Brimijoin S |
| Ref : Subcell Biochem , 12 :335 , 1988 |
| PubMedID: 3043772 |
| Title : Butyrylcholinesterase in human brain and acetylcholinesterase in human plasma: trace enzymes measured by two-site immunoassay - Brimijoin_1988_J.Neurochem_51_1227 |
| Author(s) : Brimijoin S , Hammond P |
| Ref : Journal of Neurochemistry , 51 :1227 , 1988 |
| Abstract : |
| PubMedSearch : Brimijoin_1988_J.Neurochem_51_1227 |
| PubMedID: 2901462 |
| Title : Immunoassay of acetylcholinesterase. - Brimijoin_1987_Fed.Proc_46_2557 |
| Author(s) : Brimijoin S , Rakonczay Z , Hammond P |
| Ref : Federation Proceedings , 46 :2557 , 1987 |
| Abstract : |
| PubMedSearch : Brimijoin_1987_Fed.Proc_46_2557 |
| PubMedID: 3297804 |
| Title : Two-site immunoassay for acetylcholinesterase in brain, nerve, and muscle - Brimijoin_1987_J.Neurochem_49_555 |
| Author(s) : Brimijoin S , Hammond P , Rakonczay Z |
| Ref : Journal of Neurochemistry , 49 :555 , 1987 |
| Abstract : |
| PubMedSearch : Brimijoin_1987_J.Neurochem_49_555 |
| PubMedID: 3298548 |
| Title : Monoclonal antibodies to rat brain acetylcholinesterase: comparative affinity for soluble and membrane-associated enzyme and for enzyme from different vertebrate species - Rakonczay_1986_J.Neurochem_46_280 |
| Author(s) : Rakonczay Z , Brimijoin S |
| Ref : Journal of Neurochemistry , 46 :280 , 1986 |
| Abstract : |
| PubMedSearch : Rakonczay_1986_J.Neurochem_46_280 |
| PubMedID: 3510009 |
| Title : Paroxysmal nocturnal hemoglobinuria: erythrocyte acetylcholinesterase deficit analyzed by immunoassay and fluorescence-activated sorting - Brimijoin_1986_Mayo.Clinic.Proc_61_522 |
| Author(s) : Brimijoin S , Hammond PI , Petitt RM |
| Ref : Mayo Clinic Proceedings , 61 :522 , 1986 |
| Abstract : |
| PubMedSearch : Brimijoin_1986_Mayo.Clinic.Proc_61_522 |
| PubMedID: 3520169 |
| Title : Immunochemistry of mammalian cholinesterases. - Brimijoin_1986_Fed.Proc_45_2960 |
| Author(s) : Brimijoin S , Rakonczay Z , Mintz K |
| Ref : Federation Proceedings , 45 :2960 , 1986 |
| Abstract : |
| PubMedSearch : Brimijoin_1986_Fed.Proc_45_2960 |
| PubMedID: 2430838 |
| Title : Immunology and molecular biology of the cholinesterases: current results and prospects. - |
| Author(s) : Brimijoin S , Rakonczay Z |
| Ref : International Review of Neurobiology , 28 :363 , 1986 |
| PubMedID: 2433246 |
| Title : An inhibitory monoclonal antibody to rabbit brain acetylcholinesterase. Studies on interaction with the enzyme - Brimijoin_1985_Mol.Pharmacol_28_539 |
| Author(s) : Brimijoin S , Mintz KP , Prendergast FG |
| Ref : Molecular Pharmacology , 28 :539 , 1985 |
| Abstract : |
| PubMedSearch : Brimijoin_1985_Mol.Pharmacol_28_539 |
| PubMedID: 4079910 |
| Title : Two-step immunoaffinity purification of acetylcholinesterase from rabbit brain - Mintz_1985_J.Neurochem_44_225 |
| Author(s) : Mintz KP , Brimijoin S |
| Ref : Journal of Neurochemistry , 44 :225 , 1985 |
| Abstract : |
| PubMedSearch : Mintz_1985_J.Neurochem_44_225 |
| PubMedID: 3964830 |
| Title : Human acetylcholinesterase. Immunochemical studies with monoclonal antibodies - Brimijoin_1985_Biochim.Biophys.Acta_828_290 |
| Author(s) : Brimijoin S , Mintz KP |
| Ref : Biochimica & Biophysica Acta , 828 :290 , 1985 |
| Abstract : |
| PubMedSearch : Brimijoin_1985_Biochim.Biophys.Acta_828_290 |
| PubMedID: 2580561 |
| Title : Monoclonal antibodies to rabbit brain acetylcholinesterase: selective enzyme inhibition, differential affinity for enzyme forms, and cross-reactivity with other mammalian cholinesterases - Mintz_1985_J.Neurochem_45_284 |
| Author(s) : Mintz KP , Brimijoin S |
| Ref : Journal of Neurochemistry , 45 :284 , 1985 |
| Abstract : |
| PubMedSearch : Mintz_1985_J.Neurochem_45_284 |
| PubMedID: 3889223 |
| Title : Immunochemical differences among molecular forms of acetylcholinesterase in brain and blood - Rakonczay_1985_Biochim.Biophys.Acta_832_127 |
| Author(s) : Rakonczay Z , Brimijoin S |
| Ref : Biochimica & Biophysica Acta , 832 :127 , 1985 |
| Abstract : |
| PubMedSearch : Rakonczay_1985_Biochim.Biophys.Acta_832_127 |
| PubMedID: 4063372 |
| Title : Immunochemical approaches to the study of mammalian cholinesterases - |
| Author(s) : Brimijoin S , Mintz KP |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :247 , 1984 |
| PubMedID: |
| Title : Evolution of butyrylcholinesterase in higher primates: an immunochemical study - Mintz_1984_Comp.Biochem.Physiol.C_79_35 |
| Author(s) : Mintz KP , Weinshilboum RM , Brimijoin S |
| Ref : Comparative Biochemistry & Physiology C , 79 :35 , 1984 |
| Abstract : |
| PubMedSearch : Mintz_1984_Comp.Biochem.Physiol.C_79_35 |
| PubMedID: 6149875 |
| Title : Molecular forms of acetylcholinesterase in brain, nerve and muscle: nature, localization and dynamics. - |
| Author(s) : Brimijoin S |
| Ref : Prog Neurobiol , 21 :291 , 1983 |
| PubMedID: 6198691 |
| Title : Dansylarginine N-(3-ethyl-1.5-pentanediyl)amide. A potent and selective fluorescent inhibitor of butyrylcholinesterase - Brimijoin_1983_Biochem.Pharmacol_32_699 |
| Author(s) : Brimijoin S , Mintz KP , Prendergast FG |
| Ref : Biochemical Pharmacology , 32 :699 , 1983 |
| Abstract : |
| PubMedSearch : Brimijoin_1983_Biochem.Pharmacol_32_699 |
| PubMedID: 6830632 |
| Title : Thermal inactivation of the molecular forms of acetylcholinesterase and butyrylcholinesterase - Edwards_1983_Biochim.Biophys.Acta_742_509 |
| Author(s) : Edwards JA , Brimijoin S |
| Ref : Biochimica & Biophysica Acta , 742 :509 , 1983 |
| Abstract : |
| PubMedSearch : Edwards_1983_Biochim.Biophys.Acta_742_509 |
| PubMedID: 6838885 |
| Title : Effects of hypophysectomy on acetylcholinesterase and butyrylcholinesterase in the rat - Edwards_1983_Biochem.Pharmacol_32_1183 |
| Author(s) : Edwards JA , Brimijoin S |
| Ref : Biochemical Pharmacology , 32 :1183 , 1983 |
| Abstract : |
| PubMedSearch : Edwards_1983_Biochem.Pharmacol_32_1183 |
| PubMedID: 6847710 |
| Title : Production and characterization of separate monoclonal antibodies to human acetylcholinesterase and butyrylcholinesterase - Brimijoin_1983_Mol.Pharmacol_24_513 |
| Author(s) : Brimijoin S , Mintz KP , Alley MC |
| Ref : Molecular Pharmacology , 24 :513 , 1983 |
| Abstract : |
| PubMedSearch : Brimijoin_1983_Mol.Pharmacol_24_513 |
| PubMedID: 6195517 |
| Title : Divergent regulation of acetylcholinesterase and butyrylcholinesterase in tissues of the rat - Edwards_1982_J.Neurochem_38_1393 |
| Author(s) : Edwards JA , Brimijoin S |
| Ref : Journal of Neurochemistry , 38 :1393 , 1982 |
| Abstract : |
| PubMedSearch : Edwards_1982_J.Neurochem_38_1393 |
| PubMedID: 7062057 |
| Title : Content and release of acetylcholinesterase in skeletal muscle of rats with experimental autoimmune myasthenia gravis - |
| Author(s) : Carter J , Lennon VA , Schreiber P , Brimijoin S |
| Ref : Experimental Neurology , 75 :490 , 1982 |
| PubMedID: 6980793 |
| Title : Turnover of the molecular forms of acetylcholinesterase in the rat diaphragm - Brimijoin_1982_J.Neurochem_38_588 |
| Author(s) : Brimijoin S , Carter J |
| Ref : Journal of Neurochemistry , 38 :588 , 1982 |
| Abstract : |
| PubMedSearch : Brimijoin_1982_J.Neurochem_38_588 |
| PubMedID: 7108559 |
| Title : Reduced axonal transport of 10S acetylcholinesterase in dystrophic mice - Brimijoin_1982_Muscle.Nerve_5_405 |
| Author(s) : Brimijoin S , Schreiber PA |
| Ref : Muscle & Nerve , 5 :405 , 1982 |
| Abstract : |
| PubMedSearch : Brimijoin_1982_Muscle.Nerve_5_405 |
| PubMedID: 6181401 |
| Title : Effects of acute and chronic denervation on release of acetylcholinesterase and its molecular forms in rat diaphragms - Cater_1981_J.Neurochem_36_1018 |
| Author(s) : Cater JL , Brimijoin S |
| Ref : Journal of Neurochemistry , 36 :1018 , 1981 |
| Abstract : |
| PubMedSearch : Cater_1981_J.Neurochem_36_1018 |
| PubMedID: 7205254 |
| Title : Retrograde axonal transport of transmitter enzymes, fucose-labeled protein, and nerve growth factor in streptozotocin-diabetic rats - |
| Author(s) : Jakobsen J , Brimijoin S , Skau KA , Sidenius P , Wells D |
| Ref : Diabetes , 30 :797 , 1981 |
| PubMedID: 7274587 |
| Title : Abnormal distribution of skeletal muscle acetylcholinesterase molecular forms in dystrophic mice - |
| Author(s) : Skau KA , Brimijoin S |
| Ref : Experimental Neurology , 74 :111 , 1981 |
| PubMedID: 7286112 |
| Title : Axonal transport of enzymes and labeled proteins in experimental axonopathy induced by p-bromophenylacetylurea - Jakobsen_1981_Brain.Res_229_103 |
| Author(s) : Jakobsen J , Brimijoin S |
| Ref : Brain Research , 229 :103 , 1981 |
| Abstract : |
| PubMedSearch : Jakobsen_1981_Brain.Res_229_103 |
| PubMedID: 6171326 |
| Title : Multiple molecular forms of acetylcholinesterase in rat vagus nerve, smooth muscle, and heart - Skau_1980_J.Neurochem_35_1151 |
| Author(s) : Skau KA , Brimijoin S |
| Ref : Journal of Neurochemistry , 35 :1151 , 1980 |
| Abstract : |
| PubMedSearch : Skau_1980_J.Neurochem_35_1151 |
| PubMedID: 7452310 |
| Title : Axonal transport of dopamine-beta-hydroxylase and acetylcholinesterase in human peripheral neuropathy - |
| Author(s) : Brimijoin S , Dyck PJ |
| Ref : Experimental Neurology , 66 :467 , 1979 |
| PubMedID: 226391 |
| Title : Axonal transport and subcellular distribution of molecular forms of acetylcholinesterase in rabbit sciatic nerve - Brimijoin_1979_Mol.Pharmacol_15_641 |
| Author(s) : Brimijoin S |
| Ref : Molecular Pharmacology , 15 :641 , 1979 |
| Abstract : |
| PubMedSearch : Brimijoin_1979_Mol.Pharmacol_15_641 |
| PubMedID: 91090 |
| Title : On the origin and fate of external acetylcholinesterase in peripheral nerve - Brimijoin_1978_J.Physiol_285_143 |
| Author(s) : Brimijoin S , Skau KA , Wiermaa MJ |
| Ref : The Journal of Physiology , 285 :143 , 1978 |
| Abstract : |
| PubMedSearch : Brimijoin_1978_J.Physiol_285_143 |
| PubMedID: 84869 |
| Title : Release of acetylcholinesterase from rat hemidiaphragm preparations stimulated through the phrenic nerve - |
| Author(s) : Skau KA , Brimijoin S |
| Ref : Nature , 275 :224 , 1978 |
| PubMedID: 80750 |
| Title : Rapid orthograde and retrograde axonal transport of acetylcholinesterase as characterized by the stop-flow technique - Brimijoin_1978_J.Physiol_285_129 |
| Author(s) : Brimijoin S , Wiermaa MJ |
| Ref : The Journal of Physiology , 285 :129 , 1978 |
| Abstract : |
| PubMedSearch : Brimijoin_1978_J.Physiol_285_129 |
| PubMedID: 84868 |