Brewer HB, Jr.

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Title : Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency - Sakai_1997_J.Biol.Chem_272_7506
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Title : Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis - Hoeg_1996_Proc.Natl.Acad.Sci.U.S.A_93_11448
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Title : A naturally occurring mutation at the second base of codon asparagine 43 in the proposed N-linked glycosylation site of human lipoprotein lipase: in vivo evidence that asparagine 43 is essential for catalysis and secretion - Kobayashi_1994_Biochem.Biophys.Res.Commun_205_506
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Title : Markedly accelerated catabolism of apolipoprotein A-II (ApoA-II) and high density lipoproteins containing ApoA-II in classic lecithin: cholesterol acyltransferase deficiency and fish-eye disease - Rader_1994_J.Clin.Invest_93_321
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Title : A novel missense mutation in the C-terminal domain of lipoprotein lipase (Glu410-->Val) leads to enzyme inactivation and familial chylomicronemia - Previato_1994_J.Lipid.Res_35_1552
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Gene_locus related to this paper: human-LPL

Title : Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn) - Klein_1993_J.Lipid.Res_34_49
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Title : Fish eye syndrome: a molecular defect in the lecithin-cholesterol acyltransferase (LCAT) gene associated with normal alpha-LCAT-specific activity. Implications for classification and prognosis - Klein_1993_J.Clin.Invest_92_479
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Title : Functional characterization of a chimeric lipase genetically engineered from human lipoprotein lipase and human hepatic lipase - Dichek_1993_J.Lipid.Res_34_1393
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Gene_locus related to this paper: human-LCAT

Title : Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241 - Emmerich_1992_J.Biol.Chem_267_4161
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Gene_locus related to this paper: human-LPL

Title : Identification of two separate allelic mutations in the lipoprotein lipase gene of a patient with the familial hyperchylomicronemia syndrome - Dichek_1991_J.Biol.Chem_266_473
Author(s) : Dichek HL , Fojo SS , Beg OU , Skarlatos SI , Brunzell JD , Cutler GB, Jr. , Brewer HB, Jr.
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PubMedSearch : Dichek_1991_J.Biol.Chem_266_473
PubMedID: 1702428
Gene_locus related to this paper: human-LPL

Title : Lipoprotein lipaseBethesda: a single amino acid substitution (Ala-176----Thr) leads to abnormal heparin binding and loss of enzymic activity - Beg_1990_Proc.Natl.Acad.Sci.U.S.A_87_3474
Author(s) : Beg OU , Meng MS , Skarlatos SI , Previato L , Brunzell JD , Brewer HB, Jr. , Fojo SS
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Gene_locus related to this paper: human-LPL

Title : Cholesteryl ester storage disease and Wolman disease: phenotypic variants of lysosomal acid cholesteryl ester hydrolase deficiency - Hoeg_1984_Am.J.Hum.Genet_36_1190
Author(s) : Hoeg JM , Demosky SJ, Jr. , Pescovitz OH , Brewer HB, Jr.
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Title : Initial diagnosis of lipoprotein lipase deficiency in a 75-year-old man - Hoeg_1983_Am.J.Med_75_889
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