Rader DJ

References (62)

Title : Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial - Rosenson_2023_Nat.Med__
Author(s) : Rosenson RS , Gaudet D , Ballantyne CM , Baum SJ , Bergeron J , Kershaw EE , Moriarty PM , Rubba P , Whitcomb DC , Banerjee P , Gewitz A , Gonzaga-Jauregui C , McGinniss J , Ponda MP , Pordy R , Zhao J , Rader DJ
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PubMedSearch : Rosenson_2023_Nat.Med__
PubMedID: 36879129
Gene_locus related to this paper: human-LPL

Title : Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins - Khetarpal_2021_PLoS.Genet_17_e1009802
Author(s) : Khetarpal SA , Vitali C , Levin MG , Klarin D , Park J , Pampana A , Millar JS , Kuwano T , Sugasini D , Subbaiah PV , Billheimer JT , Natarajan P , Rader DJ
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PubMedSearch : Khetarpal_2021_PLoS.Genet_17_e1009802
PubMedID: 34543263
Gene_locus related to this paper: mouse-Lipg , human-LIPG

Title : LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase -
Author(s) : Wu L , Soundarapandian MM , Castoreno AB , Millar JS , Rader DJ
Ref : Circulation Research , 127 :1112 , 2020
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Title : CRISPR\/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report - Zhang_2017_Arterioscler.Thromb.Vasc.Biol_37_2156
Author(s) : Zhang H , Shi J , Hachet MA , Xue C , Bauer RC , Jiang H , Li W , Tohyama J , Millar J , Billheimer J , Phillips MC , Razani B , Rader DJ , Reilly MP
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Title : Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease - Khera_2017_JAMA_317_937
Author(s) : Khera AV , Won HH , Peloso GM , O'Dushlaine C , Liu D , Stitziel NO , Natarajan P , Nomura A , Emdin CA , Gupta N , Borecki IB , Asselta R , Duga S , Merlini PA , Correa A , Kessler T , Wilson JG , Bown MJ , Hall AS , Braund PS , Carey DJ , Murray MF , Kirchner HL , Leader JB , Lavage DR , Manus JN , Hartzel DN , Samani NJ , Schunkert H , Marrugat J , Elosua R , McPherson R , Farrall M , Watkins H , Lander ES , Rader DJ , Danesh J , Ardissino D , Gabriel S , Willer C , Abecasis GR , Saleheen D , Dewey FE , Kathiresan S
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Gene_locus related to this paper: human-LPL

Title : Lysosomal Acid Lipase Deficiency--A New Therapy for a Genetic Lipid Disease -
Author(s) : Rader DJ
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Title : Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity - Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669
Author(s) : Miksztowicz V , Schreier L , McCoy M , Lucero D , Fassio E , Billheimer J , Rader DJ , Berg G
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Abstract :
PubMedSearch : Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669
PubMedID: 24458708
Gene_locus related to this paper: human-LIPC , human-LPL , human-LIPG

Title : Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species - Yang_2014_Lipids_49_505
Author(s) : Yang Y , Kuwano T , Lagor WR , Albert CJ , Brenton S , Rader DJ , Ford DA , Brown RJ
Ref : Lipids , 49 :505 , 2014
Abstract :
PubMedSearch : Yang_2014_Lipids_49_505
PubMedID: 24777581
Gene_locus related to this paper: human-LIPC , human-LIPG

Title : Inhibition of endothelial lipase activity by sphingomyelin in the lipoproteins - Yang_2014_Lipids_49_987
Author(s) : Yang P , Belikova NA , Billheimer J , Rader DJ , Hill JS , Subbaiah PV
Ref : Lipids , 49 :987 , 2014
Abstract :
PubMedSearch : Yang_2014_Lipids_49_987
PubMedID: 25167836
Gene_locus related to this paper: human-LIPG

Title : Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium - Tatematsu_2013_Arterioscler.Thromb.Vasc.Biol_33_1788
Author(s) : Tatematsu S , Francis SA , Natarajan P , Rader DJ , Saghatelian A , Brown JD , Michel T , Plutzky J
Ref : Arterioscler Thromb Vasc Biol , 33 :1788 , 2013
Abstract :
PubMedSearch : Tatematsu_2013_Arterioscler.Thromb.Vasc.Biol_33_1788
PubMedID: 23723371
Gene_locus related to this paper: human-LIPG

Title : Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia - Stitziel_2013_Arterioscler.Thromb.Vasc.Biol_33_2909
Author(s) : Stitziel NO , Fouchier SW , Sjouke B , Peloso GM , Moscoso AM , Auer PL , Goel A , Gigante B , Barnes TA , Melander O , Orho-Melander M , Duga S , Sivapalaratnam S , Nikpay M , Martinelli N , Girelli D , Jackson RD , Kooperberg C , Lange LA , Ardissino D , McPherson R , Farrall M , Watkins H , Reilly MP , Rader DJ , de Faire U , Schunkert H , Erdmann J , Samani NJ , Charnas L , Altshuler D , Gabriel S , Kastelein JJ , Defesche JC , Nederveen AJ , Kathiresan S , Hovingh GK
Ref : Arterioscler Thromb Vasc Biol , 33 :2909 , 2013
Abstract :
PubMedSearch : Stitziel_2013_Arterioscler.Thromb.Vasc.Biol_33_2909
PubMedID: 24072694

Title : Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics - Larach_2013_Clin.Lipidol_8_635
Author(s) : Larach DB , Cuchel M , Rader DJ
Ref : Clin Lipidol , 8 :635 , 2013
Abstract :
PubMedSearch : Larach_2013_Clin.Lipidol_8_635
PubMedID: 25374625
Gene_locus related to this paper: human-LIPG

Title : Genetics of lipid traits and relationship to coronary artery disease - Keenan_2013_Curr.Cardiol.Rep_15_396
Author(s) : Keenan TE , Rader DJ
Ref : Curr Cardiol Rep , 15 :396 , 2013
Abstract :
PubMedSearch : Keenan_2013_Curr.Cardiol.Rep_15_396
PubMedID: 23881580

Title : Design and synthesis of boronic acid inhibitors of endothelial lipase - O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397
Author(s) : O'Connell DP , LeBlanc DF , Cromley D , Billheimer J , Rader DJ , Bachovchin WW
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1397 , 2012
Abstract :
PubMedSearch : O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397
PubMedID: 22225633

Title : Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol - Khetarpal_2011_PLoS.Genet_7_e1002393
Author(s) : Khetarpal SA , Edmondson AC , Raghavan A , Neeli H , Jin W , Badellino KO , Demissie S , Manning AK , Derohannessian SL , Wolfe ML , Cupples LA , Li M , Kathiresan S , Rader DJ
Ref : PLoS Genet , 7 :e1002393 , 2011
Abstract :
PubMedSearch : Khetarpal_2011_PLoS.Genet_7_e1002393
PubMedID: 22174694
Gene_locus related to this paper: human-LIPG

Title : Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol - Edmondson_2011_Circ.Cardiovasc.Genet_4_145
Author(s) : Edmondson AC , Braund PS , Stylianou IM , Khera AV , Nelson CP , Wolfe ML , Derohannessian SL , Keating BJ , Qu L , He J , Tobin MD , Tomaszewski M , Baumert J , Klopp N , Doring A , Thorand B , Li M , Reilly MP , Koenig W , Samani NJ , Rader DJ
Ref : Circ Cardiovasc Genet , 4 :145 , 2011
Abstract :
PubMedSearch : Edmondson_2011_Circ.Cardiovasc.Genet_4_145
PubMedID: 21303902
Gene_locus related to this paper: human-LIPG

Title : VLDL hydrolysis by hepatic lipase regulates PPARdelta transcriptional responses - Brown_2011_PLoS.One_6_e21209
Author(s) : Brown JD , Oligino E , Rader DJ , Saghatelian A , Plutzky J
Ref : PLoS ONE , 6 :e21209 , 2011
Abstract :
PubMedSearch : Brown_2011_PLoS.One_6_e21209
PubMedID: 21750705

Title : Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function - Watson_2011_J.Lipid.Res_52_361
Author(s) : Watson CE , Weissbach N , Kjems L , Ayalasomayajula S , Zhang Y , Chang I , Navab M , Hama S , Hough G , Reddy ST , Soffer D , Rader DJ , Fogelman AM , Schecter A
Ref : J Lipid Res , 52 :361 , 2011
Abstract :
PubMedSearch : Watson_2011_J.Lipid.Res_52_361
PubMedID: 21068008

Title : A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease - Wild_2011_Circ.Cardiovasc.Genet_4_403
Author(s) : Wild PS , Zeller T , Schillert A , Szymczak S , Sinning CR , Deiseroth A , Schnabel RB , Lubos E , Keller T , Eleftheriadis MS , Bickel C , Rupprecht HJ , Wilde S , Rossmann H , Diemert P , Cupples LA , Perret C , Erdmann J , Stark K , Kleber ME , Epstein SE , Voight BF , Kuulasmaa K , Li M , Schafer AS , Klopp N , Braund PS , Sager HB , Demissie S , Proust C , Konig IR , Wichmann HE , Reinhard W , Hoffmann MM , Virtamo J , Burnett MS , Siscovick D , Wiklund PG , Qu L , El Mokthari NE , Thompson JR , Peters A , Smith AV , Yon E , Baumert J , Hengstenberg C , Marz W , Amouyel P , Devaney J , Schwartz SM , Saarela O , Mehta NN , Rubin D , Silander K , Hall AS , Ferrieres J , Harris TB , Melander O , Kee F , Hakonarson H , Schrezenmeir J , Gudnason V , Elosua R , Arveiler D , Evans A , Rader DJ , Illig T , Schreiber S , Bis JC , Altshuler D , Kavousi M , Witteman JC , Uitterlinden AG , Hofman A , Folsom AR , Barbalic M , Boerwinkle E , Kathiresan S , Reilly MP , O'Donnell CJ , Samani NJ , Schunkert H , Cambien F , Lackner KJ , Tiret L , Salomaa V , Munzel T , Ziegler A , Blankenberg S
Ref : Circ Cardiovasc Genet , 4 :403 , 2011
Abstract :
PubMedSearch : Wild_2011_Circ.Cardiovasc.Genet_4_403
PubMedID: 21606135
Gene_locus related to this paper: human-LIPA

Title : Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins - Brown_2010_Circ.Res_107_357
Author(s) : Brown RJ , Lagor WR , Sankaranaravanan S , Yasuda T , Quertermous T , Rothblat GH , Rader DJ
Ref : Circulation Research , 107 :357 , 2010
Abstract :
PubMedSearch : Brown_2010_Circ.Res_107_357
PubMedID: 20558822
Gene_locus related to this paper: human-LIPC , human-LIPG

Title : Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis - Yasuda_2010_Circ.J_74_2263
Author(s) : Yasuda T , Ishida T , Rader DJ
Ref : Circ J , 74 :2263 , 2010
Abstract :
PubMedSearch : Yasuda_2010_Circ.J_74_2263
PubMedID: 20962428

Title : Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases - Liu_2010_J.Biol.Chem_285_27561
Author(s) : Liu J , Afroza H , Rader DJ , Jin W
Ref : Journal of Biological Chemistry , 285 :27561 , 2010
Abstract :
PubMedSearch : Liu_2010_J.Biol.Chem_285_27561
PubMedID: 20581395

Title : The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations - Jensen_2009_Eur.Heart.J_30_1584
Author(s) : Jensen MK , Rimm EB , Mukamal KJ , Edmondson AC , Rader DJ , Vogel U , Tjonneland A , Sorensen TI , Schmidt EB , Overvad K
Ref : Eur Heart J , 30 :1584 , 2009
Abstract :
PubMedSearch : Jensen_2009_Eur.Heart.J_30_1584
PubMedID: 19411665
Gene_locus related to this paper: human-LIPG

Title : Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation - Griffon_2009_J.Biol.Chem_284_23322
Author(s) : Griffon N , Jin W , Petty TJ , Millar J , Badellino KO , Saven JG , Marchadier DH , Kempner ES , Billheimer J , Glick JM , Rader DJ
Ref : Journal of Biological Chemistry , 284 :23322 , 2009
Abstract :
PubMedSearch : Griffon_2009_J.Biol.Chem_284_23322
PubMedID: 19567873

Title : Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans - Edmondson_2009_J.Clin.Invest_119_1042
Author(s) : Edmondson AC , Brown RJ , Kathiresan S , Cupples LA , Demissie S , Manning AK , Jensen MK , Rimm EB , Wang J , Rodrigues A , Bamba V , Khetarpal SA , Wolfe ML , Derohannessian S , Li M , Reilly MP , Aberle J , Evans D , Hegele RA , Rader DJ
Ref : J Clinical Investigation , 119 :1042 , 2009
Abstract :
PubMedSearch : Edmondson_2009_J.Clin.Invest_119_1042
PubMedID: 19287092
Gene_locus related to this paper: human-LIPG

Title : A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis - Brown_2009_J.Lipid.Res_50_1910
Author(s) : Brown RJ , Edmondson AC , Griffon N , Hill TB , Fuki IV , Badellino KO , Li M , Wolfe ML , Reilly MP , Rader DJ
Ref : J Lipid Res , 50 :1910 , 2009
Abstract :
PubMedSearch : Brown_2009_J.Lipid.Res_50_1910
PubMedID: 19411705
Gene_locus related to this paper: human-LIPG

Title : Endothelial lipase is increased in vivo by inflammation in humans - Badellino_2008_Circulation_117_678
Author(s) : Badellino KO , Wolfe ML , Reilly MP , Rader DJ
Ref : Circulation , 117 :678 , 2008
Abstract :
PubMedSearch : Badellino_2008_Circulation_117_678
PubMedID: 18212282

Title : Glycosylation of endothelial lipase at asparagine-116 reduces activity and the hydrolysis of native lipoproteins in vitro and in vivo - Brown_2007_J.Lipid.Res_48_1132
Author(s) : Brown RJ , Miller GC , Griffon N , Long CJ , Rader DJ
Ref : J Lipid Res , 48 :1132 , 2007
Abstract :
PubMedSearch : Brown_2007_J.Lipid.Res_48_1132
PubMedID: 17322565

Title : Upregulation of macrophage endothelial lipase by toll-like receptors 4 and 3 modulates macrophage interleukin-10 and -12 production - Wang_2007_Circ.Res_100_1008
Author(s) : Wang X , Jin W , Rader DJ
Ref : Circulation Research , 100 :1008 , 2007
Abstract :
PubMedSearch : Wang_2007_Circ.Res_100_1008
PubMedID: 17347473

Title : N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins - Skropeta_2007_J.Lipid.Res_48_2047
Author(s) : Skropeta D , Settasatian C , McMahon MR , Shearston K , Caiazza D , McGrath KC , Jin W , Rader DJ , Barter PJ , Rye KA
Ref : J Lipid Res , 48 :2047 , 2007
Abstract :
PubMedSearch : Skropeta_2007_J.Lipid.Res_48_2047
PubMedID: 17545692

Title : Lipases as modulators of atherosclerosis in murine models - Brown_2007_Curr.Drug.Targets_8_1307
Author(s) : Brown RJ , Rader DJ
Ref : Curr Drug Targets , 8 :1307 , 2007
Abstract :
PubMedSearch : Brown_2007_Curr.Drug.Targets_8_1307
PubMedID: 18220707

Title : High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion - Ahmed_2006_Circ.Res_98_490
Author(s) : Ahmed W , Orasanu G , Nehra V , Asatryan L , Rader DJ , Ziouzenkova O , Plutzky J
Ref : Circulation Research , 98 :490 , 2006
Abstract :
PubMedSearch : Ahmed_2006_Circ.Res_98_490
PubMedID: 16439686

Title : Visceral adiposity and endothelial lipase - Paradis_2006_J.Clin.Endocrinol.Metab_91_3538
Author(s) : Paradis ME , Badellino KO , Rader DJ , Tchernof A , Richard C , Luu-The V , Deshaies Y , Bergeron J , Archer WR , Couture P , Bergeron N , Lamarche B
Ref : J Clinical Endocrinology Metab , 91 :3538 , 2006
Abstract :
PubMedSearch : Paradis_2006_J.Clin.Endocrinol.Metab_91_3538
PubMedID: 16772345

Title : Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis - Badellino_2006_PLoS.Med_3_e22
Author(s) : Badellino KO , Wolfe ML , Reilly MP , Rader DJ
Ref : PLoS Med , 3 :e22 , 2006
Abstract :
PubMedSearch : Badellino_2006_PLoS.Med_3_e22
PubMedID: 16354105

Title : Substrate specificity of lipoprotein lipase and endothelial lipase: studies of lid chimeras - Griffon_2006_J.Lipid.Res_47_1803
Author(s) : Griffon N , Budreck EC , Long CJ , Broedl UC , Marchadier DH , Glick JM , Rader DJ
Ref : J Lipid Res , 47 :1803 , 2006
Abstract :
PubMedSearch : Griffon_2006_J.Lipid.Res_47_1803
PubMedID: 16682746

Title : Endothelial lipase is associated with inflammation in humans - Paradis_2006_J.Lipid.Res_47_2808
Author(s) : Paradis ME , Badellino KO , Rader DJ , Deshaies Y , Couture P , Archer WR , Bergeron N , Lamarche B
Ref : J Lipid Res , 47 :2808 , 2006
Abstract :
PubMedSearch : Paradis_2006_J.Lipid.Res_47_2808
PubMedID: 16980590

Title : Molecular regulation of HDL metabolism and function: implications for novel therapies - Rader_2006_J.Clin.Invest_116_3090
Author(s) : Rader DJ
Ref : J Clinical Investigation , 116 :3090 , 2006
Abstract :
PubMedSearch : Rader_2006_J.Clin.Invest_116_3090
PubMedID: 17143322

Title : Regulated expression of endothelial lipase by porcine brain capillary endothelial cells constituting the blood-brain barrier - Sovic_2005_J.Neurochem_94_109
Author(s) : Sovic A , Panzenboeck U , Wintersperger A , Kratzer I , Hammer A , Levak-Frank S , Frank S , Rader DJ , Malle E , Sattler W
Ref : Journal of Neurochemistry , 94 :109 , 2005
Abstract :
PubMedSearch : Sovic_2005_J.Neurochem_94_109
PubMedID: 15953354

Title : Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation - Moore_2005_Circ.Res_97_763
Author(s) : Moore RE , Navab M , Millar JS , Zimetti F , Hama S , Rothblat GH , Rader DJ
Ref : Circulation Research , 97 :763 , 2005
Abstract :
PubMedSearch : Moore_2005_Circ.Res_97_763
PubMedID: 16151025

Title : Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue - Kratky_2005_J.Clin.Invest_115_161
Author(s) : Kratky D , Zimmermann R , Wagner EM , Strauss JG , Jin W , Kostner GM , Haemmerle G , Rader DJ , Zechner R
Ref : J Clinical Investigation , 115 :161 , 2005
Abstract :
PubMedSearch : Kratky_2005_J.Clin.Invest_115_161
PubMedID: 15630456

Title : Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I - Jahangiri_2005_J.Lipid.Res_46_896
Author(s) : Jahangiri A , Rader DJ , Marchadier D , Curtiss LK , Bonnet DJ , Rye KA
Ref : J Lipid Res , 46 :896 , 2005
Abstract :
PubMedSearch : Jahangiri_2005_J.Lipid.Res_46_896
PubMedID: 15687350

Title : Tissue-specific expression pattern of human endothelial lipase in transgenic mice - Broedl_2005_Atherosclerosis_181_271
Author(s) : Broedl UC , Jin W , Marchadier D , Secreto A , Rader DJ
Ref : Atherosclerosis , 181 :271 , 2005
Abstract :
PubMedSearch : Broedl_2005_Atherosclerosis_181_271
PubMedID: 16039280

Title : Higher order lipase gene association with plasma triglycerides - Reilly_2005_J.Lipid.Res_46_1914
Author(s) : Reilly MP , Foulkes AS , Wolfe ML , Rader DJ
Ref : J Lipid Res , 46 :1914 , 2005
Abstract :
PubMedSearch : Reilly_2005_J.Lipid.Res_46_1914
PubMedID: 15961789

Title : Gene therapy for genetic lipid disorders: lipoprotein lipase deficiency as a paradigm -
Author(s) : Rader DJ
Ref : Neth J Med , 63 :2 , 2005
PubMedID: 15719845

Title : Gain-of-function mutations and therapeutic implications: lipoprotein lipase S447X to the rescue -
Author(s) : Rader DJ
Ref : Arterioscler Thromb Vasc Biol , 25 :2018 , 2005
PubMedID: 16199757

Title : Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase - Jin_2005_J.Biol.Chem_280_36551
Author(s) : Jin W , Fuki IV , Seidah NG , Benjannet S , Glick JM , Rader DJ
Ref : Journal of Biological Chemistry , 280 :36551 , 2005
Abstract :
PubMedSearch : Jin_2005_J.Biol.Chem_280_36551
PubMedID: 16109723

Title : Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation - Broedl_2004_Trends.Cardiovasc.Med_14_202
Author(s) : Broedl UC , Jin W , Rader DJ
Ref : Trends Cardiovasc Med , 14 :202 , 2004
Abstract :
PubMedSearch : Broedl_2004_Trends.Cardiovasc.Med_14_202
PubMedID: 15261893
Gene_locus related to this paper: human-LIPG

Title : Structural basis of endothelial lipase tropism for HDL - Broedl_2004_FASEB.J_18_1891
Author(s) : Broedl UC , Jin W , Fuki IV , Glick JM , Rader DJ
Ref : FASEB Journal , 18 :1891 , 2004
Abstract :
PubMedSearch : Broedl_2004_FASEB.J_18_1891
PubMedID: 15456739
Gene_locus related to this paper: human-LIPG

Title : The role of endothelial lipase in high-density lipoprotein metabolism - Badellino_2004_Curr.Opin.Cardiol_19_392
Author(s) : Badellino KO , Rader DJ
Ref : Curr Opin Cardiol , 19 :392 , 2004
Abstract :
PubMedSearch : Badellino_2004_Curr.Opin.Cardiol_19_392
PubMedID: 15218402

Title : Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins - Broedl_2004_Circ.Res_94_1554
Author(s) : Broedl UC , Maugeais C , Millar JS , Jin W , Moore RE , Fuki IV , Marchadier D , Glick JM , Rader DJ
Ref : Circulation Research , 94 :1554 , 2004
Abstract :
PubMedSearch : Broedl_2004_Circ.Res_94_1554
PubMedID: 15117821

Title : Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway - Fuki_2003_J.Biol.Chem_278_34331
Author(s) : Fuki IV , Blanchard N , Jin W , Marchadier DH , Millar JS , Glick JM , Rader DJ
Ref : Journal of Biological Chemistry , 278 :34331 , 2003
Abstract :
PubMedSearch : Fuki_2003_J.Biol.Chem_278_34331
PubMedID: 12810721
Gene_locus related to this paper: human-LIPG

Title : Evidence that hepatic lipase and endothelial lipase have different substrate specificities for high-density lipoprotein phospholipids - Duong_2003_Biochemistry_42_13778
Author(s) : Duong M , Psaltis M , Rader DJ , Marchadier D , Barter PJ , Rye KA
Ref : Biochemistry , 42 :13778 , 2003
Abstract :
PubMedSearch : Duong_2003_Biochemistry_42_13778
PubMedID: 14622025
Gene_locus related to this paper: human-LIPC , human-LIPG

Title : Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo - Jin_2003_J.Clin.Invest_111_357
Author(s) : Jin W , Millar JS , Broedl U , Glick JM , Rader DJ
Ref : J Clinical Investigation , 111 :357 , 2003
Abstract :
PubMedSearch : Jin_2003_J.Clin.Invest_111_357
PubMedID: 12569161

Title : Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase - Maugeais_2003_Circulation_108_2121
Author(s) : Maugeais C , Tietge UJ , Broedl UC , Marchadier D , Cain W , McCoy MG , Lund-Katz S , Glick JM , Rader DJ
Ref : Circulation , 108 :2121 , 2003
Abstract :
PubMedSearch : Maugeais_2003_Circulation_108_2121
PubMedID: 14517167

Title : Lipase H, a new member of the triglyceride lipase family synthesized by the intestine - Jin_2002_Genomics_80_268
Author(s) : Jin W , Broedl UC , Monajemi H , Glick JM , Rader DJ
Ref : Genomics , 80 :268 , 2002
Abstract :
PubMedSearch : Jin_2002_Genomics_80_268
PubMedID: 12213196
Gene_locus related to this paper: human-LIPH , mouse-LIPH

Title : Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol - deLemos_2002_Circulation_106_1321
Author(s) : deLemos AS , Wolfe ML , Long CJ , Sivapackianathan R , Rader DJ
Ref : Circulation , 106 :1321 , 2002
Abstract :
PubMedSearch : deLemos_2002_Circulation_106_1321
PubMedID: 12221047
Gene_locus related to this paper: human-LIPE

Title : Characterization of the lipolytic activity of endothelial lipase - McCoy_2002_J.Lipid.Res_43_921
Author(s) : McCoy MG , Sun GS , Marchadier D , Maugeais C , Glick JM , Rader DJ
Ref : J Lipid Res , 43 :921 , 2002
Abstract :
PubMedSearch : McCoy_2002_J.Lipid.Res_43_921
PubMedID: 12032167
Gene_locus related to this paper: human-LIPG

Title : Phenotypic correction of lipid storage and growth arrest in wolman disease fibroblasts by gene transfer of lysosomal acid lipase - Tietge_2001_Hum.Gene.Ther_12_279
Author(s) : Tietge UJ , Sun G , Czarnecki S , Yu Q , Lohse P , Du H , Grabowski GA , Glick JM , Rader DJ
Ref : Hum Gene Therapy , 12 :279 , 2001
Abstract :
PubMedSearch : Tietge_2001_Hum.Gene.Ther_12_279
PubMedID: 11177564
Gene_locus related to this paper: human-LIPA

Title : Endothelial lipase: a new member of the triglyceride lipase gene family - Rader_2000_Curr.Opin.Lipidol_11_141
Author(s) : Rader DJ , Jaye M
Ref : Curr Opin Lipidol , 11 :141 , 2000
Abstract :
PubMedSearch : Rader_2000_Curr.Opin.Lipidol_11_141
PubMedID: 10787175

Title : A novel endothelial-derived lipase that modulates HDL metabolism - Jaye_1999_Nat.Genet_21_424
Author(s) : Jaye M , Lynch KJ , Krawiec J , Marchadier D , Maugeais C , Doan K , South V , Amin D , Perrone M , Rader DJ
Ref : Nat Genet , 21 :424 , 1999
Abstract :
PubMedSearch : Jaye_1999_Nat.Genet_21_424
PubMedID: 10192396
Gene_locus related to this paper: human-LIPG

Title : Markedly accelerated catabolism of apolipoprotein A-II (ApoA-II) and high density lipoproteins containing ApoA-II in classic lecithin: cholesterol acyltransferase deficiency and fish-eye disease - Rader_1994_J.Clin.Invest_93_321
Author(s) : Rader DJ , Ikewaki K , Duverger N , Schmidt H , Pritchard H , Frohlich J , Clerc M , Dumon MF , Fairwell T , Zech L , Santamarina-Fojo S , Brewer HB, Jr. , et al.
Ref : J Clinical Investigation , 93 :321 , 1994
Abstract :
PubMedSearch : Rader_1994_J.Clin.Invest_93_321
PubMedID: 8282802

Title : Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn) - Klein_1993_J.Lipid.Res_34_49
Author(s) : Klein HG , Lohse P , Duverger N , Albers JJ , Rader DJ , Zech LA , Santamarina-Fojo S , Brewer HB, Jr.
Ref : J Lipid Res , 34 :49 , 1993
Abstract :
PubMedSearch : Klein_1993_J.Lipid.Res_34_49
PubMedID: 8445342