Chiang PK

References (19)

Title : Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors - Leader_2002_J.Med.Chem_45_902
Author(s) : Leader H , Wolfe AD , Chiang PK , Gordon RK
Ref : Journal of Medicinal Chemistry , 45 :902 , 2002
Abstract :
PubMedSearch : Leader_2002_J.Med.Chem_45_902
PubMedID: 11831902

Title : 6,7,8,9-Tetrahydro-3-methyl-1H-pyrano-[4,3-b]quinolin-1-one - Hua_1999_Acta.Crystallogr.C_55 ( Pt 10)_1698
Author(s) : Hua DH , Chen Y , Sin HS , Robinson PD , Meyers CY , Perchellet EM , Perchellet JP , Chiang PK , Biellmann JF
Ref : Acta Crystallographica C , 55 ( Pt 10) :1698 , 1999
Abstract :
PubMedSearch : Hua_1999_Acta.Crystallogr.C_55 ( Pt 10)_1698
PubMedID: 10573829

Title : Monoclonal antibody AE-2 modulates carbamate and organophosphate inhibition of fetal bovine serum acetylcholinesterase - Wolfe_1993_Mol.Pharmacol_44_1152
Author(s) : Wolfe AD , Chiang PK , Doctor BP , Fryar N , Rhee JP , Saeed M
Ref : Molecular Pharmacology , 44 :1152 , 1993
Abstract :
PubMedSearch : Wolfe_1993_Mol.Pharmacol_44_1152
PubMedID: 8264551

Title : Synthesis and antimuscarinic activity of 2-[N-(ethyl)-(N-beta- hydroxyethyl)]aminoethyl 2,2-diphenylpropionate, a metabolite of aprophen - Brown_1993_J.Pharm.Sci_82_563
Author(s) : Brown ND , Leader H , Phillips LR , Smejkal RM , Gordon RK , Chiang PK
Ref : J Pharm Sci , 82 :563 , 1993
Abstract :
PubMedSearch : Brown_1993_J.Pharm.Sci_82_563
PubMedID: 8331525

Title : Relationship of three-dimensional structure of muscarinic antagonists to antimuscarinic activity: structure of thiodeacylaprophen hydrochloride - Karle_1992_Acta.Crystallogr.B_48_208
Author(s) : Karle JM , Karle IL , Gordon RK , Chiang PK
Ref : Acta Crystallographica B , 48 :208 , 1992
Abstract :
PubMedSearch : Karle_1992_Acta.Crystallogr.B_48_208
PubMedID: 1515109

Title : Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2- cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogues) - Leader_1992_J.Med.Chem_35_1290
Author(s) : Leader H , Gordon RK , Baumgold J , Boyd VL , Newman AH , Smejkal RM , Chiang PK
Ref : Journal of Medicinal Chemistry , 35 :1290 , 1992
Abstract :
PubMedSearch : Leader_1992_J.Med.Chem_35_1290
PubMedID: 1560441

Title : Isolation and identification of beta-hydroxyethylaprophen: a urinary metabolite of aprophen in rats - Brown_1991_J.Chromatogr_563_466
Author(s) : Brown ND , Phillips LR , Leader H , Chiang PK
Ref : Journal of Chromatography , 563 :466 , 1991
Abstract :
PubMedSearch : Brown_1991_J.Chromatogr_563_466
PubMedID: 2056011

Title : Aprophit: an irreversible antagonist for muscarinic receptors - Newman_1990_Biochem.Pharmacol_40_1357
Author(s) : Newman AH , Covington J , Oleshansky M , Jackson BW , Weissman BA , Leader H , Chiang PK
Ref : Biochemical Pharmacology , 40 :1357 , 1990
Abstract :
PubMedSearch : Newman_1990_Biochem.Pharmacol_40_1357
PubMedID: 2403389

Title : Structural comparison of the potent antimuscarinic agent azaprophen hydrochloride with aprophen hydrochloride and structurally related antimuscarinic agents - Karle_1990_Acta.Crystallogr.B_46_215
Author(s) : Karle JM , Karle IL , Chiang PK
Ref : Acta Crystallographica B , 46 :215 , 1990
Abstract :
PubMedSearch : Karle_1990_Acta.Crystallogr.B_46_215
PubMedID: 2344395

Title : Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates - Leader_1989_J.Med.Chem_32_1522
Author(s) : Leader H , Smejkal RM , Payne CS , Padilla FN , Doctor BP , Gordon RK , Chiang PK
Ref : Journal of Medicinal Chemistry , 32 :1522 , 1989
Abstract :
PubMedSearch : Leader_1989_J.Med.Chem_32_1522
PubMedID: 2738887

Title : Reversal of inhibition of prolactin secretion in cultured pituitary cells by muscarinic antagonists - Beach_1988_J.Pharmacol.Exp.Ther_246_548
Author(s) : Beach JE , Smallridge RC , Chiang PK , Fein HG
Ref : Journal of Pharmacology & Experimental Therapeutics , 246 :548 , 1988
Abstract :
PubMedSearch : Beach_1988_J.Pharmacol.Exp.Ther_246_548
PubMedID: 3404446

Title : Effects of muscarinic pharmacophores on the cholinergic regulation of catecholamine secretion from perfused adrenal glands - Nakazato_1988_Arch.Int.Pharmacodyn.Ther_293_209
Author(s) : Nakazato Y , Oleshansky MA , Chiang PK
Ref : Archives Internationales de Pharmacodynamie et de Therapie , 293 :209 , 1988
Abstract :
PubMedSearch : Nakazato_1988_Arch.Int.Pharmacodyn.Ther_293_209
PubMedID: 3421778

Title : Desethylaprophen: a metabolite of aprophen with antimuscarinic activities - Brown_1988_J.Pharm.Sci_77_145
Author(s) : Brown ND , Smejkal RM , Breuer E , Doctor BP , Chiang PK
Ref : J Pharm Sci , 77 :145 , 1988
Abstract :
PubMedSearch : Brown_1988_J.Pharm.Sci_77_145
PubMedID: 3258910

Title : Comparison of in vitro actions with behavioral effects of antimuscarinic agents - Witkin_1987_J.Pharmacol.Exp.Ther_242_796
Author(s) : Witkin JM , Gordon RK , Chiang PK
Ref : Journal of Pharmacology & Experimental Therapeutics , 242 :796 , 1987
Abstract :
PubMedSearch : Witkin_1987_J.Pharmacol.Exp.Ther_242_796
PubMedID: 3498817

Title : 6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent - Carroll_1987_J.Med.Chem_30_805
Author(s) : Carroll FI , Abraham P , Parham K , Griffith RC , Ahmad A , Richard MM , Padilla FN , Witkin JM , Chiang PK
Ref : Journal of Medicinal Chemistry , 30 :805 , 1987
Abstract :
PubMedSearch : Carroll_1987_J.Med.Chem_30_805
PubMedID: 3494849

Title : Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine - Miura_1986_Gen.Pharmacol_17_477
Author(s) : Miura GA , Chiang PK , Gordon RK , Doctor BP , Twine CE , Philip A , Kepler JA , Carroll FI
Ref : General Pharmacology , 17 :477 , 1986
Abstract :
PubMedSearch : Miura_1986_Gen.Pharmacol_17_477
PubMedID: 2875921

Title : Disposition of aprophen in rats - Aarbakke_1986_J.Pharm.Pharmacol_38_928
Author(s) : Aarbakke J , Miura GA , Brown ND , Gray RR , Gordon RK , Doctor BP , Chiang PK
Ref : J Pharm Pharmacol , 38 :928 , 1986
Abstract :
PubMedSearch : Aarbakke_1986_J.Pharm.Pharmacol_38_928
PubMedID: 2880971

Title : Antimuscarinic activity of aprophen -
Author(s) : Gordon RK , Padilla FN , Moore E , Doctor BP , Chiang PK
Ref : Biochemical Pharmacology , 32 :2979 , 1983
PubMedID: 6626268

Title : A radioactive assay for acetylcholinesterase using anion-exchange disk -
Author(s) : Gordon RK , Doctor BP , Chiang PK
Ref : Analytical Biochemistry , 124 :333 , 1982
PubMedID: 6756205