Doctor BP

General

Full name : Doctor Bhupendra P

First name : Bhupendra P

Mail : Division of Biochemistry\; Walter Reed Army Institute of Research\; 503 Robert Grant Road\; Silver Spring\; MD 20910

Zip Code :

City :

Country : USA

Email :

Phone :

Fax :

Website :

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References (163)

Title : Prophylaxis with human serum butyrylcholinesterase protects Gottingen minipigs exposed to a lethal high-dose of sarin vapor - Saxena_2015_Chem.Biol.Interact_238_161
Author(s) : Saxena A , Hastings NB , Sun W , Dabisch PA , Hulet SW , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Chemico-Biological Interactions , 238 :161 , 2015
PubMedID: 26145887

Title : A combination of [+] and [-]-Huperzine A improves protection against soman toxicity compared to [+]-Huperzine A in guinea pigs - Wang_2013_Chem.Biol.Interact_203_120
Author(s) : Wang Y , Wei Y , Oguntayo S , Doctor BP , Nambiar MP
Ref : Chemico-Biological Interactions , 203 :120 , 2013
PubMedID: 23123250

Title : Structural analogs of huperzine A improve survival in guinea pigs exposed to soman - Gunosewoyo_2013_Bioorg.Med.Chem.Lett_23_1544
Author(s) : Gunosewoyo H , Tipparaju SK , Pieroni M , Wang Y , Doctor BP , Nambiar MP , Kozikowski AP
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :1544 , 2013
PubMedID: 23395652

Title : Amino acid residues at the N- and C-termini are essential for the folding of active human butyrylcholinesterase polypeptide - Naik_2013_Chem.Biol.Interact_203_24
Author(s) : Naik RS , Pattabiraman N , Patel KA , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 203 :24 , 2013
PubMedID: 23044488

Title : Effect of polyethylene glycol conjugation on the circulatory stability of plasma-derived human butyrylcholinesterase in mice - Sun_2013_Chem.Biol.Interact_203_172
Author(s) : Sun W , Luo C , Tipparaju P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 203 :172 , 2013
PubMedID: 23220586

Title : Aerosolized delivery of oxime MMB-4 in combination with atropine sulfate protects against soman exposure in guinea pigs - Perkins_2012_Inhal.Toxicol_24_539
Author(s) : Perkins MW , Pierre Z , Sabnekar P , Sciuto AM , Song J , Soojhawon I , Oguntayo S , Doctor BP , Nambiar MP
Ref : Inhal Toxicol , 24 :539 , 2012
PubMedID: 22860999

Title : Characterization of human serum butyrylcholinesterase in rhesus monkeys: behavioral and physiological effects - Myers_2012_Neurotoxicol.Teratol_34_323
Author(s) : Myers TM , Sun W , Naik RS , Clark MG , Doctor BP , Saxena A
Ref : Neurotoxicology & Teratology , 34 :323 , 2012
PubMedID: 22402122

Title : Neuroprotective effects of imidazenil against chemical warfare nerve agent soman toxicity in guinea pigs - Wang_2012_Neurotoxicol_33_169
Author(s) : Wang Y , Oguntayo S , Wei Y , Wood E , Brown A , Jensen N , Auta J , Guiodotti A , Doctor BP , Nambiar MP
Ref : Neurotoxicology , 33 :169 , 2012
PubMedID: 22245390

Title : Treatment with endotracheal therapeutics after sarin microinstillation inhalation exposure increases blood cholinesterase levels in guinea pigs - Che_2012_Toxicol.Mech.Methods_22_250
Author(s) : Che MM , Song J , Oguntayo S , Doctor BP , Rezk P , Perkins MW , Sciuto AM , Nambiar MP
Ref : Toxicol Mech Methods , 22 :250 , 2012
PubMedID: 22145985

Title : Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis - Costante_2012_Toxicol.In.Vitro_26_182
Author(s) : Costante M , Biggemann L , Alamneh Y , Soojhawon I , Short R , Nigam S , Garcia G , Doctor BP , Valiyaveettil M , Nambiar MP
Ref : Toxicol In Vitro , 26 :182 , 2012
PubMedID: 22120822

Title : In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates - Valiyaveettil_2011_Toxicol.In.Vitro_25_905
Author(s) : Valiyaveettil M , Alamneh Y , Biggemann L , Soojhawon I , Farag HA , Agrawal P , Doctor BP , Nambiar MP
Ref : Toxicol In Vitro , 25 :905 , 2011
PubMedID: 21382471

Title : Recombinant paraoxonase 1 protects against sarin and soman toxicity following microinstillation inhalation exposure in guinea pigs - Valiyaveettil_2011_Toxicol.Lett_202_203
Author(s) : Valiyaveettil M , Alamneh Y , Rezk P , Perkins MW , Sciuto AM , Doctor BP , Nambiar MP
Ref : Toxicol Lett , 202 :203 , 2011
PubMedID: 21329748

Title : Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Gottingen minipigs exposed to sarin vapor - Saxena_2011_Biochem.Pharmacol_82_1984
Author(s) : Saxena A , Sun W , Dabisch PA , Hulet SW , Hastings NB , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Biochemical Pharmacology , 82 :1984 , 2011
PubMedID: 21968035

Title : Protective effects of aerosolized scopolamine against soman-induced acute respiratory toxicity in guinea pigs - Perkins_2011_Int.J.Toxicol_30_639
Author(s) : Perkins MW , Pierre Z , Rezk P , Song J , Oguntayo S , Morthole V , Sciuto AM , Doctor BP , Nambiar MP
Ref : Int J Toxicol , 30 :639 , 2011
PubMedID: 21960666

Title : Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX - Saxena_2011_Biochem.Pharmacol_81_164
Author(s) : Saxena A , Sun W , Fedorko JM , Koplovitz I , Doctor BP
Ref : Biochemical Pharmacology , 81 :164 , 2011
PubMedID: 20846507

Title : Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs - Valiyaveettil_2011_Biochem.Pharmacol_81_800
Author(s) : Valiyaveettil M , Alamneh Y , Rezk P , Biggemann L , Perkins MW , Sciuto AM , Doctor BP , Nambiar MP
Ref : Biochemical Pharmacology , 81 :800 , 2011
PubMedID: 21219877

Title : Systemic administration of the potential countermeasure huperzine reversibly inhibits central and peripheral acetylcholinesterase activity without adverse cognitive-behavioral effects - Myers_2010_Pharmacol.Biochem.Behav_94_477
Author(s) : Myers TM , Sun W , Saxena A , Doctor BP , Bonvillain AJ , Clark MG
Ref : Pharmacol Biochem Behav , 94 :477 , 2010
PubMedID: 19909771

Title : Gastrointestinal acetylcholinesterase activity following endotracheal microinstillation inhalation exposure to sarin in guinea pigs - Chanda_2010_Chem.Biol.Interact_187_309
Author(s) : Chanda S , Song J , Rezk P , Sabnekar P , Doctor BP , Sciuto AM , Nambiar MP
Ref : Chemico-Biological Interactions , 187 :309 , 2010
PubMedID: 20227400

Title : Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats - Genovese_2010_Basic.Clin.Pharmacol.Toxicol_106_428
Author(s) : Genovese RF , Sun W , Johnson CC , diTargiani RC , Doctor BP , Saxena A
Ref : Basic Clin Pharmacol Toxicol , 106 :428 , 2010
PubMedID: 20050840

Title : Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model - Rosenberg_2010_Chem.Biol.Interact_187_279
Author(s) : Rosenberg YJ , Saxena A , Sun W , Jiang X , Chilukuri N , Luo C , Doctor BP , Lee KD
Ref : Chemico-Biological Interactions , 187 :279 , 2010
PubMedID: 20211615

Title : Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1 - Valiyaveettil_2010_Biochem.Biophys.Res.Commun_403_97
Author(s) : Valiyaveettil M , Alamneh Y , Biggemann L , Soojhawon I , Doctor BP , Nambiar MP
Ref : Biochemical & Biophysical Research Communications , 403 :97 , 2010
PubMedID: 21040699

Title : Acute respiratory toxicity following inhalation exposure to soman in guinea pigs - Perkins_2010_Toxicol.Appl.Pharmacol_245_171
Author(s) : Perkins MW , Pierre Z , Rezk P , Sabnekar P , Kabra K , Chanda S , Oguntayo S , Sciuto AM , Doctor BP , Nambiar MP
Ref : Toxicol Appl Pharmacol , 245 :171 , 2010
PubMedID: 20206646

Title : Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its aged soman conjugate - Gabel_2009_Biophys.J_96_1489
Author(s) : Gabel F , Masson P , Froment MT , Doctor BP , Saxena A , Silman I , Zaccai G , Weik M
Ref : Biophysical Journal , 96 :1489 , 2009
PubMedID: 19217865

Title : Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents - Chilukuri_2009_Mol.Pharmacol_76_612
Author(s) : Chilukuri N , Duysen EG , Parikh K , diTargiani RC , Doctor BP , Lockridge O , Saxena A
Ref : Molecular Pharmacology , 76 :612 , 2009
PubMedID: 19542320

Title : Pharmacokinetics and immunologic consequences of repeated administrations of purified heterologous and homologous butyrylcholinesterase in mice - Sun_2009_Life.Sci_85_657
Author(s) : Sun W , Luo C , Naik RS , Doctor BP , Saxena A
Ref : Life Sciences , 85 :657 , 2009
PubMedID: 19772863

Title : The IXth International Meeting on Cholinesterases, Suzhou, People's Republic of China, 6 to 10 May 2007 -
Author(s) : Doctor BP , Tsim KWK , Siow NL
Ref : Chemico-Biological Interactions , 175 :1 , 2008
PubMedID: 18582448

Title : A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice - Chilukuri_2008_Toxicol.Appl.Pharmacol_231_423
Author(s) : Chilukuri N , Sun W , Parikh K , Naik RS , Tang L , Doctor BP , Saxena A
Ref : Toxicol Appl Pharmacol , 231 :423 , 2008
PubMedID: 18586293

Title : Developing procedures for the large-scale purification of human serum butyrylcholinesterase - Saxena_2008_Protein.Expr.Purif_61_191
Author(s) : Saxena A , Luo C , Doctor BP
Ref : Protein Expr Purif , 61 :191 , 2008
PubMedID: 18602477

Title : Long-term effects of human butyrylcholinesterase pretreatment followed by acute soman challenge in cynomolgus monkeys - Sun_2008_Chem.Biol.Interact_175_428
Author(s) : Sun W , Doctor BP , Lenz DE , Saxena A
Ref : Chemico-Biological Interactions , 175 :428 , 2008
PubMedID: 18674756

Title : [+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure\/status epilepticus in rats - Coleman_2008_Chem.Biol.Interact_175_387
Author(s) : Coleman BR , Ratcliffe RH , Oguntayo SA , Shi X , Doctor BP , Gordon RK , Nambiar MP
Ref : Chemico-Biological Interactions , 175 :387 , 2008
PubMedID: 18588864

Title : Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo - Chilukuri_2008_Chem.Biol.Interact_175_327
Author(s) : Chilukuri N , Duysen EG , Parikh K , Sun W , Doctor BP , Lockridge O , Saxena A
Ref : Chemico-Biological Interactions , 175 :327 , 2008
PubMedID: 18499092

Title : Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase - Chilukuri_2008_Chem.Biol.Interact_175_255
Author(s) : Chilukuri N , Sun W , Naik RS , Parikh K , Tang L , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 175 :255 , 2008
PubMedID: 18603232

Title : Comparison of methods used for the determination of cholinesterase activity in whole blood - Naik_2008_Chem.Biol.Interact_175_298
Author(s) : Naik RS , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 175 :298 , 2008
PubMedID: 18555980

Title : Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines - Curtin_2008_J.Cell.Biochem_103_1524
Author(s) : Curtin BF , Seetharam KI , Dhoieam P , Gordon RK , Doctor BP , Nambiar MP
Ref : Journal of Cellular Biochemistry , 103 :1524 , 2008
PubMedID: 17879943

Title : Efficacy of human serum butyrylcholinesterase against sarin vapor - Saxena_2008_Chem.Biol.Interact_175_267
Author(s) : Saxena A , Sun W , Dabisch PA , Hulet SW , Hastings NB , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Chemico-Biological Interactions , 175 :267 , 2008
PubMedID: 18597747

Title : Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase - Haigh_2008_Chem.Biol.Interact_175_380
Author(s) : Haigh JR , Johnston SR , Peppernay A , Mattern PJ , Garcia GE , Doctor BP , Gordon RK , Aisen PS
Ref : Chemico-Biological Interactions , 175 :380 , 2008
PubMedID: 18572153

Title : Advantages of the WRAIR whole blood cholinesterase assay: comparative analysis to the micro-Ellman, Test-mate ChE, and Michel (DeltapH) assays - Haigh_2008_Chem.Biol.Interact_175_417
Author(s) : Haigh JR , Lefkowitz LJ , Capacio BR , Doctor BP , Gordon RK
Ref : Chemico-Biological Interactions , 175 :417 , 2008
PubMedID: 18555983

Title : Acute toxic effects of nerve agent VX on respiratory dynamics and functions following microinsillation inhalation exposure in guinea pigs - Rezk_2007_Inhal.Toxicol_19_291
Author(s) : Rezk PE , Graham JR , Moran TS , Gordon RK , Sciuto AM , Doctor BP , Nambiar MP
Ref : Inhal Toxicol , 19 :291 , 2007
PubMedID: 17365032

Title : Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs - Katos_2007_Toxicol.Ind.Health_23_231
Author(s) : Katos AM , Conti ML , Moran TS , Gordon RK , Doctor BP , Sciuto AM , Nambiar MP
Ref : Toxicol Ind Health , 23 :231 , 2007
PubMedID: 18429383

Title : Celastrus paniculatus seed oil and organic extracts attenuate hydrogen peroxide- and glutamate-induced injury in embryonic rat forebrain neuronal cells - Godkar_2006_Phytomedicine_13_29
Author(s) : Godkar PB , Gordon RK , Ravindran A , Doctor BP
Ref : Phytomedicine , 13 :29 , 2006
PubMedID: 16360930

Title : Bioscavenger for protection from toxicity of organophosphorus compounds - Saxena_2006_J.Mol.Neurosci_30_145
Author(s) : Saxena A , Sun W , Luo C , Myers TM , Koplovitz I , Lenz DE , Doctor BP
Ref : Journal of Molecular Neuroscience , 30 :145 , 2006
PubMedID: 17192662

Title : Polyethylene glycosylation prolongs the circulatory stability of recombinant human butyrylcholinesterase - Chilukuri_2005_Chem.Biol.Interact_157-158_115
Author(s) : Chilukuri N , Parikh K , Sun W , Naik R , Tipparaju P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :115 , 2005
PubMedID: 16253215

Title : Safety and pharmacokinetics of human serum butyrylcholinesterase in guinea pigs - Sun_2005_Chem.Biol.Interact_157-158_428
Author(s) : Sun W , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :428 , 2005
PubMedID: 16429577

Title : In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger - Cerasoli_2005_Chem.Biol.Interact_157-158_363
Author(s) : Cerasoli DM , Griffiths EM , Doctor BP , Saxena A , Fedorko JM , Greig NH , Yu QS , Huang Y , Wilgus H , Karatzas CN , Koplovitz I , Lenz DE
Ref : Chemico-Biological Interactions , 157-158 :363 , 2005
PubMedID: 16429486

Title : Effects of physostigmine and human butyrylcholinesterase on acoustic startle reflex and prepulse inhibition in C57BL\/6J mice - Clark_2005_Pharmacol.Biochem.Behav_81_497
Author(s) : Clark MG , Sun W , Myers TM , Bansal R , Doctor BP , Saxena A
Ref : Pharmacol Biochem Behav , 81 :497 , 2005
PubMedID: 15913750

Title : Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents - Nambiar_2005_Chem.Biol.Interact_157-158_409
Author(s) : Nambiar MP , Curtin BF , Pal N , Compton JR , Doctor BP , Gordon RK
Ref : Chemico-Biological Interactions , 157-158 :409 , 2005
PubMedID: 16429504

Title : Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure - Curtin_2005_J.Cell.Biochem_96_839
Author(s) : Curtin BF , Tetz LM , Compton JR , Doctor BP , Gordon RK , Nambiar MP
Ref : Journal of Cellular Biochemistry , 96 :839 , 2005
PubMedID: 16149071

Title : Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys - Lenz_2005_Chem.Biol.Interact_157-158_205
Author(s) : Lenz DE , Maxwell DM , Koplovitz I , Clark CR , Capacio BR , Cerasoli DM , Federko JM , Luo C , Saxena A , Doctor BP , Olson C
Ref : Chemico-Biological Interactions , 157-158 :205 , 2005
PubMedID: 16289064

Title : An ex vivo approach for the evaluation of reversible inhibitors as potential pretreatments against organophosphate toxicity - Tonduli_2005_Chem.Biol.Interact_157-158_426
Author(s) : Tonduli LS , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :426 , 2005
PubMedID: 16429574

Title : Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases -
Author(s) : Luo C , Dawson M , Chambers C , Chilukuri N , Radic Z , Taylor P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :393 , 2005
PubMedID: 16429528

Title : Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity -
Author(s) : Haigh JR , Johnston SR , Peters BM , Doctor BP , Gordon RK , Adler M , Gall KJ , Deshpande SS
Ref : Chemico-Biological Interactions , 157-158 :381 , 2005
PubMedID: 16429510

Title : Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman - Gordon_2005_Chem.Biol.Interact_157-158_239
Author(s) : Gordon RK , Haigh JR , Garcia GE , Feaster SR , Riel MA , Lenz DE , Aisen PS , Doctor BP
Ref : Chemico-Biological Interactions , 157-158 :239 , 2005
PubMedID: 16256090

Title : Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study - Gabel_2005_Biophys.J_89_3303
Author(s) : Gabel F , Weik M , Masson P , Renault F , Fournier D , Brochier L , Doctor BP , Saxena A , Silman I , Zaccai G
Ref : Biophysical Journal , 89 :3303 , 2005
PubMedID: 16100272

Title : Human serum butyrylcholinesterase: in vitro and in vivo stability, pharmacokinetics, and safety in mice - Saxena_2005_Chem.Biol.Interact_157-158_199
Author(s) : Saxena A , Sun W , Luo C , Doctor BP
Ref : Chemico-Biological Interactions , 157-158 :199 , 2005
PubMedID: 16263104

Title : Bioscavengers for the protection of humans against organophosphate toxicity - Doctor_2005_Chem.Biol.Interact_157-158_167
Author(s) : Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :167 , 2005
PubMedID: 16293236

Title : Poster (81) Interaction of beta-amyloid and cholinesterases by fluorescent polarization -
Author(s) : Nigam SV , Doctor BP , Gordon RK
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :363 , 2004
PubMedID:

Title : The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study - Gabel_2004_Biophys.J_86_3152
Author(s) : Gabel F , Weik M , Doctor BP , Saxena A , Fournier D , Brochier L , Renault F , Masson P , Silman I , Zaccai G
Ref : Biophysical Journal , 86 :3152 , 2004
PubMedID: 15111428

Title : Interaction of beta-amyloid and cholinesterases by fluorescent polarization -
Author(s) : Nigam SV , Doctor BP , Gordon RK
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :171 , 2004
PubMedID:

Title : Poster (15) Molecular recognition in AChE catalysis - the view from near and far. -
Author(s) : Moussavi-Harami F , Sikorski RS , Quinn DM , Feaster SR , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :328 , 2004
PubMedID:

Title : Detection and identification of chemical warfare Agents polyurethane immobilized enzymes -
Author(s) : Gordon RK , Gunduz AT , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :243 , 2004
PubMedID:

Title : Strategy for reactivation of organophosphate-inhibited human butyrylcholinesterase -
Author(s) : Luo C , Dawson M , Maxwell DM , Doctor BP , Saxena A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :251 , 2004
PubMedID:

Title : Human serum butyrylcholinesterase: A future generation antidote for organophosphate chemical warfare agent toxicity . -
Author(s) : Saxena A , Luo C , Bansal R , Sun W , Clark M , Ashani Y , Ross M , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :269 , 2004
PubMedID:

Title : Poster (30) Detection and identification of chemical warfare agents polyurethane immobilized enzymes -
Author(s) : Gordon RK , Gunduz AT , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :336 , 2004
PubMedID:

Title : Poster (32) Bioscavengers: antidotes for organophosphate chemical warfare agent toxicity. -
Author(s) : Doctor BP , Saxena A , Ashani Y , Ross M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :337 , 2004
PubMedID:

Title : Poster (33) Strategy for the reactivation of organophosphate-inhibited human butyrylcholinesterase -
Author(s) : Luo C , McKissic D , Doctor BP , Saxena A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :338 , 2004
PubMedID:

Title : Poster (36) Human serum butyrylcholinesterase: a future generation antidote for organophosphate chemical warfare agent toxicity -
Author(s) : Saxena A , Luo C , Bansal R , Sun W , Clark M , Ashani Y , Ross M , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :339 , 2004
PubMedID:

Title : Protective effect of equine butyrylcholinesterase in inhalation intoxication of rats with sarin: determination of blood and brain cholinesterase activities - Sevelova_2004_Inhal.Toxicol_16_531
Author(s) : Sevelova L , Bajgar J , Saxena A , Doctor BP
Ref : Inhal Toxicol , 16 :531 , 2004
PubMedID: 15204744

Title : Polyurethane immobilized enzymes. -
Author(s) : Gordon RK , Gunduz AT , Doctor BP , Cronin T
Ref : Cholinergic Mechanisms, CRC Press :265 , 2004
PubMedID:

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. -
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Cholinergic Mechanisms, CRC Press :627 , 2004
PubMedID:

Title : Natural monomeric form of fetal bovine serum acetylcholinesterase lacks the C-terminal tetramerization domain - Saxena_2003_Biochemistry_42_15292
Author(s) : Saxena A , Hur RS , Luo C , Doctor BP
Ref : Biochemistry , 42 :15292 , 2003
PubMedID: 14690439

Title : Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases - Saxena_2003_Eur.J.Biochem_270_4447
Author(s) : Saxena A , Fedorko JM , Vinayaka CR , Medhekar R , Radic Z , Taylor P , Lockridge O , Doctor BP
Ref : European Journal of Biochemistry , 270 :4447 , 2003
PubMedID: 14622273

Title : Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators - Ashani_2003_Biochem.Pharmacol_66_191
Author(s) : Ashani Y , Bhattacharjee AK , Leader H , Saxena A , Doctor BP
Ref : Biochemical Pharmacology , 66 :191 , 2003
PubMedID: 12826262

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase - Luo_2003_Biochem.Pharmacol_66_387
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Biochemical Pharmacology , 66 :387 , 2003
PubMedID: 12907237

Title : Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B - Rajendran_2002_Bioorg.Med.Chem.Lett_12_1521
Author(s) : Rajendran V , Saxena A , Doctor BP , Kozikowski AP
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :1521 , 2002
PubMedID: 12031333

Title : Pharmacokinetics and immunologic consequences of exposing macaques to purified homologous butyrylcholinesterase - Rosenberg_2002_Life.Sci_72_125
Author(s) : Rosenberg YJ , Luo C , Ashani Y , Doctor BP , Fischer R , Wolfe G , Saxena A
Ref : Life Sciences , 72 :125 , 2002
PubMedID: 12417246

Title : The NMDA receptor ion channel: a site for binding of Huperzine A - Gordon_2001_J.Appl.Toxicol_21 Suppl 1_S47
Author(s) : Gordon RK , Nigam SV , Weitz JA , Dave JR , Doctor BP , Ved HS
Ref : J Appl Toxicol , 21 Suppl 1 :S47 , 2001
PubMedID: 11920920

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
PubMedID: 10421446

Title : Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1999_Chem.Biol.Interact_119-120_61
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :61 , 1999
PubMedID: 10421439

Title : Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases - Maxwell_1999_Chem.Biol.Interact_119-120_419
Author(s) : Maxwell DM , Saxena A , Gordon RK , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :419 , 1999
PubMedID: 10421479

Title : Organophosphate skin decontamination using immobilized enzymes - Gordon_1999_Chem.Biol.Interact_119-120_463
Author(s) : Gordon RK , Feaster SR , Russell AJ , LeJeune KE , Maxwell DM , Lenz DE , Ross M , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :463 , 1999
PubMedID: 10421484

Title : Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium - Luo_1999_Biochemistry_38_9937
Author(s) : Luo C , Saxena A , Smith M , Garcia GE , Radic Z , Taylor P , Doctor BP
Ref : Biochemistry , 38 :9937 , 1999
PubMedID: 10433700

Title : Allosteric control of acetylcholinesterase activity by monoclonal antibodies -
Author(s) : Saxena A , Hur RS , Doctor BP
Ref : Biochemistry , 38 :15688 , 1999
PubMedID: 10569956

Title : Comparative Effects of Cholinesterase Inhibitors on Glutamate-Induced Neuronal Cell Death -
Author(s) : Ved HS , Dave JR , Nguyen T , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :181 , 1998
PubMedID:

Title : Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Acetylcholinesterase by Quaternary Ligands -
Author(s) : Luo C , Ashani Y , Saxena A , Leader H , Maxwell DM , Taylor P , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :215 , 1998
PubMedID:

Title : Synthesis and anticholinesterase activity of huperzine A analogues containing phenol and catechol replacements for the pyridone ring - Campiani_1998_Bioorg.Med.Chem.Lett_8_1413
Author(s) : Campiani G , Kozikowski AP , Wang S , Ming L , Nacci V , Saxena A , Doctor BP
Ref : Bioorganic & Medicinal Chemistry Lett , 8 :1413 , 1998
PubMedID: 9871776

Title : Stable Complexes Involving Acetylcholinesterase and Amyloid-beta Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer's Fibrils - Alvarez_1998_J.Neurosci_18_3213
Author(s) : Alvarez A , Alarcon R , Opazo C , Campos EO , Munoz FJ , Calderon FH , Dajas F , Gentry MK , Doctor BP , de Mello FG , Inestrosa NC
Ref : Journal of Neuroscience , 18 :3213 , 1998
PubMedID: 9547230

Title : Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Fetal Bovine Serum Acetylcholinesterase by Monoquaternary and Bisquaternary Ligands - Luo_1998_Mol.Pharmacol_53_718
Author(s) : Luo C , Ashani Y , Doctor BP
Ref : Molecular Pharmacology , 53 :718 , 1998
PubMedID: 9547363

Title : pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants -
Author(s) : Viragh C , Saxena A , Frazier DS , Kovach IM , Lockridge O , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :247 , 1998
PubMedID:

Title : Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon - Amitai_1998_Biochem.Pharmacol_56_293
Author(s) : Amitai G , Moorad DR , Adani R , Doctor BP
Ref : Biochemical Pharmacology , 56 :293 , 1998
PubMedID: 9744565

Title : Acceleration of oxime-induced reactivation of acetylcholinesterase-organophosphate conjugate and 31P NMR detection of phosporyl oxime from the conjugate -
Author(s) : Luo C , Ashani Y , Doctor BP
Ref : Journal de Physiologie (Paris) , 92 :461 , 1998
PubMedID:

Title : A Comparison of Blood Cholinesterase Activities, Pyridostigmine Inhibition of Red Cell Acetylcholinesterase, and Butyrylcholinesterase Phenotypes in Gulf War Veterans and Normal Controls -
Author(s) : Gentry MK , Powell S , Bitsko N , Bartels CF , Bartko J , Chung R , Lockridge O , Ribas J , Roy M , Malone J , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :300 , 1998
PubMedID:

Title : The Role of Oligosaccharides in the Pharmacokinetics of Cholinesterases -
Author(s) : Saxena A , Ashani Y , Raveh L , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :283 , 1998
PubMedID:

Title : Characterization of ChEs Immobilized on Polyurethane Foams -
Author(s) : Gordon RK , Feaster SR , Herron PC II , Lowe ER , LeJeune KE , Russell AJ , Lenz DE , Ross M , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :307 , 1998
PubMedID:

Title : Allosteric control of acetylcholinesterase activity by monoclonal antibodies - Saxena_1998_Biochemistry_37_145
Author(s) : Saxena A , Hur RS , Doctor BP
Ref : Biochemistry , 37 :145 , 1998
PubMedID: 9425034

Title : The pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants: Further Evidence for a Push-Pull Mechanism - Saxena_1998_Biochemistry_37_15086
Author(s) : Saxena A , Viragh C , Frazier DS , Kovach IM , Maxwell DM , Lockridge O , Doctor BP
Ref : Biochemistry , 37 :15086 , 1998
PubMedID: 9790671

Title : Amino Acid Sequence of Horse Serum Butyrylcholinesterase -
Author(s) : Moorad DR , Luo C , Saxena A , Doctor BP , Garcia GE
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :145 , 1998
PubMedID:
Gene_locus related to this paper: horse-BCHE

Title : Comparison of Cholinesterases and Carboxylesterase as Bioscavengers for Organophosphorus Compounds -
Author(s) : Maxwell DM , Brecht KM , Saxena A , Feaster SR , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :387 , 1998
PubMedID:

Title : Role of oligosaccharides in the pharmacokinetics of tissue-derived and genetically engineered cholinesterases - Saxena_1998_Mol.Pharmacol_53_112
Author(s) : Saxena A , Ashani Y , Raveh L , Stevenson D , Patel T , Doctor BP
Ref : Molecular Pharmacology , 53 :112 , 1998
PubMedID: 9443938

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
PubMedID: 9271331

Title : A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme - Reyes_1997_Biochem.Biophys.Res.Commun_232_652
Author(s) : Reyes AE , Perez DR , Alvarez A , Garrido J , Gentry MK , Doctor BP , Inestrosa NC
Ref : Biochemical & Biophysical Research Communications , 232 :652 , 1997
PubMedID: 9126330

Title : Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1997_Biochemistry_36_14642
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Biochemistry , 36 :14642 , 1997
PubMedID: 9398183

Title : Structure of glycan moieties responsible for the extended circulatory life time of fetal bovine serum acetylcholinesterase and equine serum butyrylcholinesterase - Saxena_1997_Biochemistry_36_7481
Author(s) : Saxena A , Raveh L , Ashani Y , Doctor BP
Ref : Biochemistry , 36 :7481 , 1997
PubMedID: 9200697

Title : Reversal of Glycerol Ether-Stimulated Acetylcholinesterase Activity by c-fos Antisense Oligonucleotide in Primary Neuronal Cultures -
Author(s) : Dave JR , Fasnacht E , Tortella FC , Best JM , Doctor BP , Ved HS
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :289 , 1995
PubMedID:

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Different effects of two peripheral anionic site-binding ligands on acetylcholinesterase active-site gorge topography revealed by electron paramagnetic resonance - Grubic_1995_Biochim.Biophys.Acta_1249_155
Author(s) : Grubic Z , Stalc A , Sentjurc M , Pecar S , Gentry MK , Doctor BP
Ref : Biochimica & Biophysica Acta , 1249 :155 , 1995
PubMedID: 7599168

Title : Horse Serum Butyrylcholinesterase Does Not Disrupt Passive Avoidance Learning or Spontaneous Motor Activity in Rats -
Author(s) : Genovese RF , Roberts AR , Fantegrossi WE , Larrison RW , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :473 , 1995
PubMedID:

Title : Comparative Inhibition of Acetylcholinesterase by Tacrine, Physostigmine and Huperzine in the Adult Rat Brain -
Author(s) : Ved HS , Best JM , Dave JR , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :477 , 1995
PubMedID:

Title : Characterization of monoclonal antibodies that inhibit the catalytic activity of acetylcholinesterases - Gentry_1995_J.Neurochem_64_842
Author(s) : Gentry MK , Moorad DR , Hur RS , Saxena A , Ashani Y , Doctor BP
Ref : Journal of Neurochemistry , 64 :842 , 1995
PubMedID: 7830078

Title : Amino Acid Alignment of Cholinesterases, Esterases, Lipases, and Related Proteins -
Author(s) : Gentry MK , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :493 , 1995
PubMedID:

Title : Structural Analysis of the Asparagine-Linked Oligosaccharides of Cholinesterases -
Author(s) : Saxena A , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :105 , 1995
PubMedID:

Title : Alterations in the Topography of Acetylcholinesterase Active Site Gorge after Binding of Peripheral Anionic Site Ligands -
Author(s) : Stalc A , Grubic Z , Sentjurc M , Pecar S , Gentry MK , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :125 , 1995
PubMedID:

Title : Comparison of Acetylcholinesterase, Pyridostigmine, and HI-6 as Antidotes against Organophosphorus Compounds -
Author(s) : Maxwell DM , Brecht KM , Saxena A , Taylor P , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :353 , 1995
PubMedID:

Title : Modulation of Catalysis and Inhibition of Fetal Bovine Serum Acetylcholinesterase by Monoclonal Antibodies -
Author(s) : Doctor BP , Gentry MK , Saxena A , Ashani Y
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :141 , 1995
PubMedID:

Title : Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes - Ashani_1995_J.Biol.Chem_270_6370
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : Journal of Biological Chemistry , 270 :6370 , 1995
PubMedID: 7890775

Title : Behavioral and pharmacological assessment of butyrylcholinesterase in rats - Genovese_1995_Pharmacol.Biochem.Behav_51_647
Author(s) : Genovese RF , Doctor BP
Ref : Pharmacology, Biochemistry & Behavior , 51 :647 , 1995
PubMedID: 7675838

Title : Huperzine A as a pretreatment candidate drug against nerve agent toxicity - Grunwald_1994_Life.Sci_54_991
Author(s) : Grunwald J , Raveh L , Doctor BP , Ashani Y
Ref : Life Sciences , 54 :991 , 1994
PubMedID: 8139389

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
PubMedID: 7849595

Title : Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes - Caranto_1994_Biochem.Pharmacol_47_347
Author(s) : Caranto GR , Waibel KH , Asher JM , Larrison RW , Brecht KM , Schutz MB , Raveh L , Ashani Y , Wolfe AD , Maxwell DM , Doctor BP
Ref : Biochemical Pharmacology , 47 :347 , 1994
PubMedID: 8304979

Title : Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy - Segall_1993_Biochemistry_32_13441
Author(s) : Segall Y , Waysbort D , Barak D , Ariel N , Doctor BP , Grunwald J , Ashani Y
Ref : Biochemistry , 32 :13441 , 1993
PubMedID: 8257680

Title : Monoclonal antibody AE-2 modulates carbamate and organophosphate inhibition of fetal bovine serum acetylcholinesterase - Wolfe_1993_Mol.Pharmacol_44_1152
Author(s) : Wolfe AD , Chiang PK , Doctor BP , Fryar N , Rhee JP , Saeed M
Ref : Molecular Pharmacology , 44 :1152 , 1993
PubMedID: 8264551

Title : Comparison of antidote protection against soman by pyridostigmine, HI-6 and acetylcholinesterase - Maxwell_1993_J.Pharmacol.Exp.Ther_264_1085
Author(s) : Maxwell DM , Brecht KM , Doctor BP , Wolfe AD
Ref : Journal of Pharmacology & Experimental Therapeutics , 264 :1085 , 1993
PubMedID: 8450452

Title : The role of glutamate-199 in the aging of cholinesterase - Saxena_1993_Biochem.Biophys.Res.Commun_197_343
Author(s) : Saxena A , Doctor BP , Maxwell DM , Lenz DE , Radic Z , Taylor P
Ref : Biochemical & Biophysical Research Communications , 197 :343 , 1993
PubMedID: 7902714

Title : Cholinesterases as scavengers for organophosphorus compounds: protection of primate performance against soman toxicity - Doctor_1993_Chem.Biol.Interact_87_285
Author(s) : Doctor BP , Blick DW , Caranto G , Castro CA , Gentry MK , Larrison RW , Maxwell DM , Murphy MR , Schutz MB , Waibel KH , Wolfe AD
Ref : Chemico-Biological Interactions , 87 :285 , 1993
PubMedID: 8343986

Title : Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins - Cygler_1993_Protein.Sci_2_366
Author(s) : Cygler M , Schrag JD , Sussman JL , Harel M , Silman I , Gentry MK , Doctor BP
Ref : Protein Science , 2 :366 , 1993
PubMedID: 8453375

Title : Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies - Gentry_1993_Chem.Biol.Interact_87_227
Author(s) : Gentry MK , Saxena A , Ashani Y , Doctor BP
Ref : Chemico-Biological Interactions , 87 :227 , 1993
PubMedID: 7688272

Title : Epitope mapping of form-specific and nonspecific antibodies to acetylcholinesterase - Wasserman_1993_J.Neurochem_61_2124
Author(s) : Wasserman L , Doctor BP , Gentry MK , Taylor P
Ref : Journal of Neurochemistry , 61 :2124 , 1993
PubMedID: 7504082

Title : Protection of rhesus monkeys against soman and prevention of performance decrement by pretreatment with acetylcholinesterase - Maxwell_1992_Toxicol.Appl.Pharmacol_115_44
Author(s) : Maxwell DM , Castro CA , De La Hoz DM , Gentry MK , Gold MB , Solana RP , Wolfe AD , Doctor BP
Ref : Toxicology & Applied Pharmacology , 115 :44 , 1992
PubMedID: 1631892

Title : A microtiter assay for determining protein, acetylcholinesterase activity, and G418 (Neomycin) resistance in cultured cells - Elson_1992_Anal.Biochem_200_268
Author(s) : Elson HF , Gentry MK , Doctor BP
Ref : Analytical Biochemistry , 200 :268 , 1992
PubMedID: 1378703

Title : Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity - Wolfe_1992_Toxicol.Appl.Pharmacol_117_189
Author(s) : Wolfe AD , Blick DW , Murphy MR , Miller SA , Gentry MK , Hartgraves SL , Doctor BP
Ref : Toxicology & Applied Pharmacology , 117 :189 , 1992
PubMedID: 1471150

Title : Membrane-bound acetylcholinesterase: an early differentiation marker for skeletal myoblasts - Elson_1992_Biochim.Biophys.Acta_1156_78
Author(s) : Elson HF , Gentry MK , Doctor BP
Ref : Biochimica & Biophysica Acta , 1156 :78 , 1992
PubMedID: 1472543

Title : Mechanism of inhibition of cholinesterases by huperzine A - Ashani_1992_Biochem.Biophys.Res.Commun_184_719
Author(s) : Ashani Y , Peggins JO, 3rd , Doctor BP
Ref : Biochemical & Biophysical Research Communications , 184 :719 , 1992
PubMedID: 1575745

Title : Acetylcholinesterase: A Pretreatment Drug for Organophosphate Toxicity -
Author(s) : Doctor BP , Blick DW
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :277 , 1992
PubMedID:

Title : APPENDIX Alignment of Amino Acid Sequences of Acetylcholinesterases and Butyrylcholinesterases -
Author(s) : Gentry MK , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :394 , 1991
PubMedID:

Title : Poster: Esterases as organophosphate scavengers -
Author(s) : Wolfe AD , Ashani Y , Doctor BP , Maxwell DM
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :306 , 1991
PubMedID:

Title : Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice - Ashani_1991_Biochem.Pharmacol_41_37
Author(s) : Ashani Y , Shapira S , Levy D , Wolfe AD , Doctor BP , Raveh L
Ref : Biochemical Pharmacology , 41 :37 , 1991
PubMedID: 1986743

Title : Bovine Brain Acetylcholinesterase Sequence Involved in Intersubunit Disulfide Linkages -
Author(s) : Rosenberry TL , Roberts WL , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :17 , 1991
PubMedID:

Title : Fetal Bovine Serum Acetylcholinesterase: Structure-Function Correlation -
Author(s) : Doctor BP , Gentry MK , Wu SJ , Ashani Y , De La Hoz DM
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :37 , 1991
PubMedID:

Title : Bovine brain acetylcholinesterase primary sequence involved in intersubunit disulfide linkages - Roberts_1991_J.Biol.Chem_266_7481
Author(s) : Roberts WL , Doctor BP , Foster JD , Rosenberry TL
Ref : Journal of Biological Chemistry , 266 :7481 , 1991
PubMedID: 2019579

Title : Cholinesterase and Carboxyl esterase as Scavengers for Organophosphorus Agents -
Author(s) : Maxwell DM , Wolfe AD , Ashani Y , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :206 , 1991
PubMedID:

Title : Changes in the Catalytic Activity of Acetylcholinesterase upon Complexation with Monoclonal Antibodies -
Author(s) : Ashani Y , Bromberg A , Levy D , Gentry MK , Brady DR , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :235 , 1991
PubMedID:

Title : Enzymes as pretreatment drugs for organophosphate toxicity - Doctor_1991_Neurosci.Biobehav.Rev_15_123
Author(s) : Doctor BP , Raveh L , Wolfe AD , Maxwell DM , Ashani Y
Ref : Neurosci Biobehav Rev , 15 :123 , 1991
PubMedID: 2052184

Title : Differences in conformational stability between native and phosphorylated acetylcholinesterase as evidenced by a monoclonal antibody - Ashani_1990_Biochemistry_29_2456
Author(s) : Ashani Y , Gentry MK , Doctor BP
Ref : Biochemistry , 29 :2456 , 1990
PubMedID: 1692236

Title : Studies on the topography of the catalytic site of acetylcholinesterase using polyclonal and monoclonal antibodies - Ogert_1990_J.Neurochem_55_756
Author(s) : Ogert RA , Gentry MK , Richardson EC , Deal CD , Abramson SN , Alving CR , Taylor P , Doctor BP
Ref : Journal of Neurochemistry , 55 :756 , 1990
PubMedID: 1696619

Title : Complete amino acid sequence of fetal bovine serum acetylcholinesterase and its comparison in various regions with other cholinesterases - Doctor_1990_FEBS.Lett_266_123
Author(s) : Doctor BP , Chapman TC , Christner CE , Deal CD , De La Hoz DM , Gentry MK , Ogert RA , Rush RS , Smyth KK , Wolfe AD
Ref : FEBS Letters , 266 :123 , 1990
PubMedID: 2365060
Gene_locus related to this paper: bovin-ACHE

Title : Acetylcholinesterase prophylaxis against organophosphate poisoning. Quantitative correlation between protection and blood-enzyme level in mice - Raveh_1989_Biochem.Pharmacol_38_529
Author(s) : Raveh L , Ashani Y , Levy D , De La Hoz DM , Wolfe AD , Doctor BP
Ref : Biochemical Pharmacology , 38 :529 , 1989
PubMedID: 2917010

Title : Structural and immunochemical properties of fetal bovine serum acetylcholinesterase -
Author(s) : Doctor BP , Smyth KK , Gentry MK , Ashani Y , Christner CE , De La Hoz DM , Ogert RA , Smith SW
Ref : Progress in Clinical & Biological Research , 289 :305 , 1989
PubMedID: 2471207

Title : Differences in structure and distribution of the molecular forms of acetylcholinesterase - Abramson_1989_J.Cell.Biol_108_2301
Author(s) : Abramson SN , Ellisman MH , Deerinck TJ , Maulet Y , Gentry MK , Doctor BP , Taylor P
Ref : Journal of Cell Biology , 108 :2301 , 1989
PubMedID: 2472404

Title : Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates - Leader_1989_J.Med.Chem_32_1522
Author(s) : Leader H , Smejkal RM , Payne CS , Padilla FN , Doctor BP , Gordon RK , Chiang PK
Ref : Journal of Medicinal Chemistry , 32 :1522 , 1989
PubMedID: 2738887

Title : Desethylaprophen: a metabolite of aprophen with antimuscarinic activities - Brown_1988_J.Pharm.Sci_77_145
Author(s) : Brown ND , Smejkal RM , Breuer E , Doctor BP , Chiang PK
Ref : J Pharm Sci , 77 :145 , 1988
PubMedID: 3258910

Title : Acetylcholinesterase prophylaxis against organophosphate toxicity - Wolfe_1987_Fundam.Appl.Toxicol_9_266
Author(s) : Wolfe AD , Rush RS , Doctor BP , Koplovitz I , Jones D
Ref : Fundamental & Applied Toxicology , 9 :266 , 1987
PubMedID: 3653568

Title : Microtiter assay for acetylcholinesterase - Doctor_1987_Anal.Biochem_166_399
Author(s) : Doctor BP , Toker L , Roth E , Silman I
Ref : Analytical Biochemistry , 166 :399 , 1987
PubMedID: 3434781

Title : Kinetic investigations into the interactions of aprophen with cholinesterases and a carboxylesterase - Rush_1986_Biochem.Pharmacol_35_4167
Author(s) : Rush RS , Doctor BP , Wolfe AD
Ref : Biochemical Pharmacology , 35 :4167 , 1986
PubMedID: 3098245

Title : Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine - Miura_1986_Gen.Pharmacol_17_477
Author(s) : Miura GA , Chiang PK , Gordon RK , Doctor BP , Twine CE , Philip A , Kepler JA , Carroll FI
Ref : General Pharmacology , 17 :477 , 1986
PubMedID: 2875921

Title : A simplified procedure for the purification of large quantities of fetal bovine serum acetylcholinesterase - De La Hoz_1986_Life.Sci_39_195
Author(s) : De La Hoz DM , Doctor BP , Ralston JS , Rush RS , Wolfe AD
Ref : Life Sciences , 39 :195 , 1986
PubMedID: 3736320

Title : Disposition of aprophen in rats - Aarbakke_1986_J.Pharm.Pharmacol_38_928
Author(s) : Aarbakke J , Miura GA , Brown ND , Gray RR , Gordon RK , Doctor BP , Chiang PK
Ref : J Pharm Pharmacol , 38 :928 , 1986
PubMedID: 2880971

Title : Acetylcholinesterase from fetal bovine serum. Purification and characterization of soluble G4 enzyme - Ralston_1985_J.Biol.Chem_260_4312
Author(s) : Ralston JS , Rush RS , Doctor BP , Wolfe AD
Ref : Journal of Biological Chemistry , 260 :4312 , 1985
PubMedID: 3980478

Title : Molecular aspects of the biosynthesis and disposition of multiple forms of acetylcholinesterase -
Author(s) : Taylor P , Camp S , Lee SL , Amitai G , Taylor SS , Doctor BP
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :145 , 1984
PubMedID:

Title : Stability study of HI-6 dichloride in various anticholinergic formulations -
Author(s) : Brown ND , Gray RR , Stermer-Cox MG , Doctor BP , Hagedorn I
Ref : Journal of Chromatography , 315 :389 , 1984
PubMedID: 6526905

Title : Poster 8. Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase -
Author(s) : Doctor BP , Taylor P
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984
PubMedID:

Title : Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase - Doctor_1983_Proc.Natl.Acad.Sci.U.S.A_80_5767
Author(s) : Doctor BP , Camp S , Gentry MK , Taylor SS , Taylor P
Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :5767 , 1983
PubMedID: 6193524

Title : Antimuscarinic activity of aprophen -
Author(s) : Gordon RK , Padilla FN , Moore E , Doctor BP , Chiang PK
Ref : Biochemical Pharmacology , 32 :2979 , 1983
PubMedID: 6626268

Title : A radioactive assay for acetylcholinesterase using anion-exchange disk -
Author(s) : Gordon RK , Doctor BP , Chiang PK
Ref : Analytical Biochemistry , 124 :333 , 1982
PubMedID: 6756205

Title : Inhibition of ribonucleic acid degradation in bacteria by spermine -
Author(s) : Herbst EJ , Doctor BP
Ref : Journal of Biological Chemistry , 234 :1497 , 1959
PubMedID: 13654404