Doctor BP

General

Full name : Doctor Bhupendra P

First name : Bhupendra P

Mail : Division of Biochemistry\; Walter Reed Army Institute of Research\; 503 Robert Grant Road\; Silver Spring\; MD 20910

Zip Code :

City :

Country : USA

Email :

Phone :

Fax :

Website :

Directory :

Comment
Bhupendra P. Doctor, also known as BP or Doc, was born in 1930 in India and died in 2014 in Maryland, US. He was the Director of the Division of Biochemistry at The Walter Reed Army Institute of Research in Washington, D.C. (now Silver Spring, MD). With many colleagues he produced monoclonal antibodies to AChE; purified, sequenced and cloned bovine AChE; and spearheaded the use of BChE as a stoichiometric scavenger of organophosphate compounds. He investigated the mechanisms of cholinesterase catalysis, alkylphosphate inhibition and nucleophilic reactivation. A tribute to BP by Palmer Taylor can be found here BPDoctor.pdf.

References (166)

Title : Prophylaxis with human serum butyrylcholinesterase protects Gottingen minipigs exposed to a lethal high-dose of sarin vapor - Saxena_2015_Chem.Biol.Interact_238_161
Author(s) : Saxena A , Hastings NB , Sun W , Dabisch PA , Hulet SW , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Chemico-Biological Interactions , 238 :161 , 2015
Abstract :
PubMedSearch : Saxena_2015_Chem.Biol.Interact_238_161
PubMedID: 26145887

Title : Structural analogs of huperzine A improve survival in guinea pigs exposed to soman - Gunosewoyo_2013_Bioorg.Med.Chem.Lett_23_1544
Author(s) : Gunosewoyo H , Tipparaju SK , Pieroni M , Wang Y , Doctor BP , Nambiar MP , Kozikowski AP
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :1544 , 2013
Abstract :
PubMedSearch : Gunosewoyo_2013_Bioorg.Med.Chem.Lett_23_1544
PubMedID: 23395652

Title : Amino acid residues at the N- and C-termini are essential for the folding of active human butyrylcholinesterase polypeptide - Naik_2013_Chem.Biol.Interact_203_24
Author(s) : Naik RS , Pattabiraman N , Patel KA , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 203 :24 , 2013
Abstract :
PubMedSearch : Naik_2013_Chem.Biol.Interact_203_24
PubMedID: 23044488

Title : Effect of polyethylene glycol conjugation on the circulatory stability of plasma-derived human butyrylcholinesterase in mice - Sun_2013_Chem.Biol.Interact_203_172
Author(s) : Sun W , Luo C , Tipparaju P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 203 :172 , 2013
Abstract :
PubMedSearch : Sun_2013_Chem.Biol.Interact_203_172
PubMedID: 23220586

Title : A combination of [+] and [-]-Huperzine A improves protection against soman toxicity compared to [+]-Huperzine A in guinea pigs - Wang_2013_Chem.Biol.Interact_203_120
Author(s) : Wang Y , Wei Y , Oguntayo S , Doctor BP , Nambiar MP
Ref : Chemico-Biological Interactions , 203 :120 , 2013
Abstract :
PubMedSearch : Wang_2013_Chem.Biol.Interact_203_120
PubMedID: 23123250

Title : Aerosolized delivery of oxime MMB-4 in combination with atropine sulfate protects against soman exposure in guinea pigs - Perkins_2012_Inhal.Toxicol_24_539
Author(s) : Perkins MW , Pierre Z , Sabnekar P , Sciuto AM , Song J , Soojhawon I , Oguntayo S , Doctor BP , Nambiar MP
Ref : Inhal Toxicol , 24 :539 , 2012
Abstract :
PubMedSearch : Perkins_2012_Inhal.Toxicol_24_539
PubMedID: 22860999

Title : Treatment with endotracheal therapeutics after sarin microinstillation inhalation exposure increases blood cholinesterase levels in guinea pigs - Che_2012_Toxicol.Mech.Methods_22_250
Author(s) : Che MM , Song J , Oguntayo S , Doctor BP , Rezk P , Perkins MW , Sciuto AM , Nambiar MP
Ref : Toxicol Mech Methods , 22 :250 , 2012
Abstract :
PubMedSearch : Che_2012_Toxicol.Mech.Methods_22_250
PubMedID: 22145985

Title : Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis - Costante_2012_Toxicol.In.Vitro_26_182
Author(s) : Costante M , Biggemann L , Alamneh Y , Soojhawon I , Short R , Nigam S , Garcia G , Doctor BP , Valiyaveettil M , Nambiar MP
Ref : Toxicol In Vitro , 26 :182 , 2012
Abstract :
PubMedSearch : Costante_2012_Toxicol.In.Vitro_26_182
PubMedID: 22120822

Title : Characterization of human serum butyrylcholinesterase in rhesus monkeys: behavioral and physiological effects - Myers_2012_Neurotoxicol.Teratol_34_323
Author(s) : Myers TM , Sun W , Naik RS , Clark MG , Doctor BP , Saxena A
Ref : Neurotoxicology & Teratology , 34 :323 , 2012
Abstract :
PubMedSearch : Myers_2012_Neurotoxicol.Teratol_34_323
PubMedID: 22402122

Title : Neuroprotective effects of imidazenil against chemical warfare nerve agent soman toxicity in guinea pigs - Wang_2012_Neurotoxicol_33_169
Author(s) : Wang Y , Oguntayo S , Wei Y , Wood E , Brown A , Jensen N , Auta J , Guiodotti A , Doctor BP , Nambiar MP
Ref : Neurotoxicology , 33 :169 , 2012
Abstract :
PubMedSearch : Wang_2012_Neurotoxicol_33_169
PubMedID: 22245390

Title : In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates - Valiyaveettil_2011_Toxicol.In.Vitro_25_905
Author(s) : Valiyaveettil M , Alamneh Y , Biggemann L , Soojhawon I , Farag HA , Agrawal P , Doctor BP , Nambiar MP
Ref : Toxicol In Vitro , 25 :905 , 2011
Abstract :
PubMedSearch : Valiyaveettil_2011_Toxicol.In.Vitro_25_905
PubMedID: 21382471

Title : Recombinant paraoxonase 1 protects against sarin and soman toxicity following microinstillation inhalation exposure in guinea pigs - Valiyaveettil_2011_Toxicol.Lett_202_203
Author(s) : Valiyaveettil M , Alamneh Y , Rezk P , Perkins MW , Sciuto AM , Doctor BP , Nambiar MP
Ref : Toxicol Lett , 202 :203 , 2011
Abstract :
PubMedSearch : Valiyaveettil_2011_Toxicol.Lett_202_203
PubMedID: 21329748

Title : Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs - Valiyaveettil_2011_Biochem.Pharmacol_81_800
Author(s) : Valiyaveettil M , Alamneh Y , Rezk P , Biggemann L , Perkins MW , Sciuto AM , Doctor BP , Nambiar MP
Ref : Biochemical Pharmacology , 81 :800 , 2011
Abstract :
PubMedSearch : Valiyaveettil_2011_Biochem.Pharmacol_81_800
PubMedID: 21219877

Title : Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Gottingen minipigs exposed to sarin vapor - Saxena_2011_Biochem.Pharmacol_82_1984
Author(s) : Saxena A , Sun W , Dabisch PA , Hulet SW , Hastings NB , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Biochemical Pharmacology , 82 :1984 , 2011
Abstract :
PubMedSearch : Saxena_2011_Biochem.Pharmacol_82_1984
PubMedID: 21968035

Title : Protective effects of aerosolized scopolamine against soman-induced acute respiratory toxicity in guinea pigs - Perkins_2011_Int.J.Toxicol_30_639
Author(s) : Perkins MW , Pierre Z , Rezk P , Song J , Oguntayo S , Morthole V , Sciuto AM , Doctor BP , Nambiar MP
Ref : Int J Toxicol , 30 :639 , 2011
Abstract :
PubMedSearch : Perkins_2011_Int.J.Toxicol_30_639
PubMedID: 21960666

Title : Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX - Saxena_2011_Biochem.Pharmacol_81_164
Author(s) : Saxena A , Sun W , Fedorko JM , Koplovitz I , Doctor BP
Ref : Biochemical Pharmacology , 81 :164 , 2011
Abstract :
PubMedSearch : Saxena_2011_Biochem.Pharmacol_81_164
PubMedID: 20846507

Title : Endotracheal aerosolization of atropine sulfate protects against soman-induced acute respiratory toxicity in guinea pigs - Perkins_2011_Inhal.Toxicol_23_182
Author(s) : Perkins MW , Pierre Z , Rezk P , Song J , Marshall S , Oguntayo S , Morthole V , Sciuto AM , Doctor BP , Nambiar MP
Ref : Inhal Toxicol , 23 :182 , 2011
Abstract :
PubMedSearch : Perkins_2011_Inhal.Toxicol_23_182
PubMedID: 21456952

Title : Acute changes in pulmonary function following microinstillation inhalation exposure to soman in nonatropenized guinea pigs - Perkins_2011_Int.J.Toxicol_30_348
Author(s) : Perkins MW , Pierre Z , Rezk P , Song J , Oguntayo S , Sciuto AM , Doctor BP , Nambiar MP
Ref : Int J Toxicol , 30 :348 , 2011
Abstract :
PubMedSearch : Perkins_2011_Int.J.Toxicol_30_348
PubMedID: 21527644

Title : Systemic administration of the potential countermeasure huperzine reversibly inhibits central and peripheral acetylcholinesterase activity without adverse cognitive-behavioral effects - Myers_2010_Pharmacol.Biochem.Behav_94_477
Author(s) : Myers TM , Sun W , Saxena A , Doctor BP , Bonvillain AJ , Clark MG
Ref : Pharmacol Biochem Behav , 94 :477 , 2010
Abstract :
PubMedSearch : Myers_2010_Pharmacol.Biochem.Behav_94_477
PubMedID: 19909771

Title : Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats - Genovese_2010_Basic.Clin.Pharmacol.Toxicol_106_428
Author(s) : Genovese RF , Sun W , Johnson CC , diTargiani RC , Doctor BP , Saxena A
Ref : Basic Clin Pharmacol Toxicol , 106 :428 , 2010
Abstract :
PubMedSearch : Genovese_2010_Basic.Clin.Pharmacol.Toxicol_106_428
PubMedID: 20050840

Title : Gastrointestinal acetylcholinesterase activity following endotracheal microinstillation inhalation exposure to sarin in guinea pigs - Chanda_2010_Chem.Biol.Interact_187_309
Author(s) : Chanda S , Song J , Rezk P , Sabnekar P , Doctor BP , Sciuto AM , Nambiar MP
Ref : Chemico-Biological Interactions , 187 :309 , 2010
Abstract :
PubMedSearch : Chanda_2010_Chem.Biol.Interact_187_309
PubMedID: 20227400

Title : Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1 - Valiyaveettil_2010_Biochem.Biophys.Res.Commun_403_97
Author(s) : Valiyaveettil M , Alamneh Y , Biggemann L , Soojhawon I , Doctor BP , Nambiar MP
Ref : Biochemical & Biophysical Research Communications , 403 :97 , 2010
Abstract :
PubMedSearch : Valiyaveettil_2010_Biochem.Biophys.Res.Commun_403_97
PubMedID: 21040699

Title : Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model - Rosenberg_2010_Chem.Biol.Interact_187_279
Author(s) : Rosenberg YJ , Saxena A , Sun W , Jiang X , Chilukuri N , Luo C , Doctor BP , Lee KD
Ref : Chemico-Biological Interactions , 187 :279 , 2010
Abstract :
PubMedSearch : Rosenberg_2010_Chem.Biol.Interact_187_279
PubMedID: 20211615

Title : Acute respiratory toxicity following inhalation exposure to soman in guinea pigs - Perkins_2010_Toxicol.Appl.Pharmacol_245_171
Author(s) : Perkins MW , Pierre Z , Rezk P , Sabnekar P , Kabra K , Chanda S , Oguntayo S , Sciuto AM , Doctor BP , Nambiar MP
Ref : Toxicol Appl Pharmacol , 245 :171 , 2010
Abstract :
PubMedSearch : Perkins_2010_Toxicol.Appl.Pharmacol_245_171
PubMedID: 20206646

Title : Pharmacokinetics and immunologic consequences of repeated administrations of purified heterologous and homologous butyrylcholinesterase in mice - Sun_2009_Life.Sci_85_657
Author(s) : Sun W , Luo C , Naik RS , Doctor BP , Saxena A
Ref : Life Sciences , 85 :657 , 2009
Abstract :
PubMedSearch : Sun_2009_Life.Sci_85_657
PubMedID: 19772863

Title : Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its aged soman conjugate - Gabel_2009_Biophys.J_96_1489
Author(s) : Gabel F , Masson P , Froment MT , Doctor BP , Saxena A , Silman I , Zaccai G , Weik M
Ref : Biophysical Journal , 96 :1489 , 2009
Abstract :
PubMedSearch : Gabel_2009_Biophys.J_96_1489
PubMedID: 19217865

Title : Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents - Chilukuri_2009_Mol.Pharmacol_76_612
Author(s) : Chilukuri N , Duysen EG , Parikh K , diTargiani RC , Doctor BP , Lockridge O , Saxena A
Ref : Molecular Pharmacology , 76 :612 , 2009
Abstract :
PubMedSearch : Chilukuri_2009_Mol.Pharmacol_76_612
PubMedID: 19542320

Title : Comparison of methods used for the determination of cholinesterase activity in whole blood - Naik_2008_Chem.Biol.Interact_175_298
Author(s) : Naik RS , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 175 :298 , 2008
Abstract :
PubMedSearch : Naik_2008_Chem.Biol.Interact_175_298
PubMedID: 18555980

Title : [+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure\/status epilepticus in rats - Coleman_2008_Chem.Biol.Interact_175_387
Author(s) : Coleman BR , Ratcliffe RH , Oguntayo SA , Shi X , Doctor BP , Gordon RK , Nambiar MP
Ref : Chemico-Biological Interactions , 175 :387 , 2008
Abstract :
PubMedSearch : Coleman_2008_Chem.Biol.Interact_175_387
PubMedID: 18588864

Title : Efficacy of human serum butyrylcholinesterase against sarin vapor - Saxena_2008_Chem.Biol.Interact_175_267
Author(s) : Saxena A , Sun W , Dabisch PA , Hulet SW , Hastings NB , Jakubowski EM , Mioduszewski RJ , Doctor BP
Ref : Chemico-Biological Interactions , 175 :267 , 2008
Abstract :
PubMedSearch : Saxena_2008_Chem.Biol.Interact_175_267
PubMedID: 18597747

Title : Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase - Haigh_2008_Chem.Biol.Interact_175_380
Author(s) : Haigh JR , Johnston SR , Peppernay A , Mattern PJ , Garcia GE , Doctor BP , Gordon RK , Aisen PS
Ref : Chemico-Biological Interactions , 175 :380 , 2008
Abstract :
PubMedSearch : Haigh_2008_Chem.Biol.Interact_175_380
PubMedID: 18572153

Title : Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines - Curtin_2008_J.Cell.Biochem_103_1524
Author(s) : Curtin BF , Seetharam KI , Dhoieam P , Gordon RK , Doctor BP , Nambiar MP
Ref : Journal of Cellular Biochemistry , 103 :1524 , 2008
Abstract :
PubMedSearch : Curtin_2008_J.Cell.Biochem_103_1524
PubMedID: 17879943

Title : Advantages of the WRAIR whole blood cholinesterase assay: comparative analysis to the micro-Ellman, Test-mate ChE, and Michel (DeltapH) assays - Haigh_2008_Chem.Biol.Interact_175_417
Author(s) : Haigh JR , Lefkowitz LJ , Capacio BR , Doctor BP , Gordon RK
Ref : Chemico-Biological Interactions , 175 :417 , 2008
Abstract :
PubMedSearch : Haigh_2008_Chem.Biol.Interact_175_417
PubMedID: 18555983

Title : The IXth International Meeting on Cholinesterases, Suzhou, People's Republic of China, 6 to 10 May 2007 -
Author(s) : Doctor BP , Tsim KWK , Siow NL
Ref : Chemico-Biological Interactions , 175 :1 , 2008
PubMedID: 18582448

Title : A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice - Chilukuri_2008_Toxicol.Appl.Pharmacol_231_423
Author(s) : Chilukuri N , Sun W , Parikh K , Naik RS , Tang L , Doctor BP , Saxena A
Ref : Toxicol Appl Pharmacol , 231 :423 , 2008
Abstract :
PubMedSearch : Chilukuri_2008_Toxicol.Appl.Pharmacol_231_423
PubMedID: 18586293

Title : Developing procedures for the large-scale purification of human serum butyrylcholinesterase - Saxena_2008_Protein.Expr.Purif_61_191
Author(s) : Saxena A , Luo C , Doctor BP
Ref : Protein Expr Purif , 61 :191 , 2008
Abstract :
PubMedSearch : Saxena_2008_Protein.Expr.Purif_61_191
PubMedID: 18602477

Title : Long-term effects of human butyrylcholinesterase pretreatment followed by acute soman challenge in cynomolgus monkeys - Sun_2008_Chem.Biol.Interact_175_428
Author(s) : Sun W , Doctor BP , Lenz DE , Saxena A
Ref : Chemico-Biological Interactions , 175 :428 , 2008
Abstract :
PubMedSearch : Sun_2008_Chem.Biol.Interact_175_428
PubMedID: 18674756

Title : Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo - Chilukuri_2008_Chem.Biol.Interact_175_327
Author(s) : Chilukuri N , Duysen EG , Parikh K , Sun W , Doctor BP , Lockridge O , Saxena A
Ref : Chemico-Biological Interactions , 175 :327 , 2008
Abstract :
PubMedSearch : Chilukuri_2008_Chem.Biol.Interact_175_327
PubMedID: 18499092

Title : Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase - Chilukuri_2008_Chem.Biol.Interact_175_255
Author(s) : Chilukuri N , Sun W , Naik RS , Parikh K , Tang L , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 175 :255 , 2008
Abstract :
PubMedSearch : Chilukuri_2008_Chem.Biol.Interact_175_255
PubMedID: 18603232

Title : Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs - Katos_2007_Toxicol.Ind.Health_23_231
Author(s) : Katos AM , Conti ML , Moran TS , Gordon RK , Doctor BP , Sciuto AM , Nambiar MP
Ref : Toxicol Ind Health , 23 :231 , 2007
Abstract :
PubMedSearch : Katos_2007_Toxicol.Ind.Health_23_231
PubMedID: 18429383

Title : Acute toxic effects of nerve agent VX on respiratory dynamics and functions following microinsillation inhalation exposure in guinea pigs - Rezk_2007_Inhal.Toxicol_19_291
Author(s) : Rezk PE , Graham JR , Moran TS , Gordon RK , Sciuto AM , Doctor BP , Nambiar MP
Ref : Inhal Toxicol , 19 :291 , 2007
Abstract :
PubMedSearch : Rezk_2007_Inhal.Toxicol_19_291
PubMedID: 17365032

Title : Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX - Nambiar_2007_Toxicol.Appl.Pharmacol_219_142
Author(s) : Nambiar MP , Gordon RK , Rezk PE , Katos AM , Wajda NA , Moran TS , Steele KE , Doctor BP , Sciuto AM
Ref : Toxicol Appl Pharmacol , 219 :142 , 2007
Abstract :
PubMedSearch : Nambiar_2007_Toxicol.Appl.Pharmacol_219_142
PubMedID: 17188727

Title : Bioscavenger for protection from toxicity of organophosphorus compounds - Saxena_2006_J.Mol.Neurosci_30_145
Author(s) : Saxena A , Sun W , Luo C , Myers TM , Koplovitz I , Lenz DE , Doctor BP
Ref : Journal of Molecular Neuroscience , 30 :145 , 2006
Abstract :
PubMedSearch : Saxena_2006_J.Mol.Neurosci_30_145
PubMedID: 17192662

Title : Celastrus paniculatus seed oil and organic extracts attenuate hydrogen peroxide- and glutamate-induced injury in embryonic rat forebrain neuronal cells - Godkar_2006_Phytomedicine_13_29
Author(s) : Godkar PB , Gordon RK , Ravindran A , Doctor BP
Ref : Phytomedicine , 13 :29 , 2006
Abstract :
PubMedSearch : Godkar_2006_Phytomedicine_13_29
PubMedID: 16360930

Title : Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman - Gordon_2005_Chem.Biol.Interact_157-158_239
Author(s) : Gordon RK , Haigh JR , Garcia GE , Feaster SR , Riel MA , Lenz DE , Aisen PS , Doctor BP
Ref : Chemico-Biological Interactions , 157-158 :239 , 2005
Abstract :
PubMedSearch : Gordon_2005_Chem.Biol.Interact_157-158_239
PubMedID: 16256090

Title : Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study - Gabel_2005_Biophys.J_89_3303
Author(s) : Gabel F , Weik M , Masson P , Renault F , Fournier D , Brochier L , Doctor BP , Saxena A , Silman I , Zaccai G
Ref : Biophysical Journal , 89 :3303 , 2005
Abstract :
PubMedSearch : Gabel_2005_Biophys.J_89_3303
PubMedID: 16100272

Title : Human serum butyrylcholinesterase: in vitro and in vivo stability, pharmacokinetics, and safety in mice - Saxena_2005_Chem.Biol.Interact_157-158_199
Author(s) : Saxena A , Sun W , Luo C , Doctor BP
Ref : Chemico-Biological Interactions , 157-158 :199 , 2005
Abstract :
PubMedSearch : Saxena_2005_Chem.Biol.Interact_157-158_199
PubMedID: 16263104

Title : Bioscavengers for the protection of humans against organophosphate toxicity - Doctor_2005_Chem.Biol.Interact_157-158_167
Author(s) : Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :167 , 2005
Abstract :
PubMedSearch : Doctor_2005_Chem.Biol.Interact_157-158_167
PubMedID: 16293236

Title : Safety and pharmacokinetics of human serum butyrylcholinesterase in guinea pigs - Sun_2005_Chem.Biol.Interact_157-158_428
Author(s) : Sun W , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :428 , 2005
Abstract :
PubMedSearch : Sun_2005_Chem.Biol.Interact_157-158_428
PubMedID: 16429577

Title : Polyethylene glycosylation prolongs the circulatory stability of recombinant human butyrylcholinesterase - Chilukuri_2005_Chem.Biol.Interact_157-158_115
Author(s) : Chilukuri N , Parikh K , Sun W , Naik R , Tipparaju P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :115 , 2005
Abstract :
PubMedSearch : Chilukuri_2005_Chem.Biol.Interact_157-158_115
PubMedID: 16253215

Title : Effects of physostigmine and human butyrylcholinesterase on acoustic startle reflex and prepulse inhibition in C57BL\/6J mice - Clark_2005_Pharmacol.Biochem.Behav_81_497
Author(s) : Clark MG , Sun W , Myers TM , Bansal R , Doctor BP , Saxena A
Ref : Pharmacol Biochem Behav , 81 :497 , 2005
Abstract :
PubMedSearch : Clark_2005_Pharmacol.Biochem.Behav_81_497
PubMedID: 15913750

Title : In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger - Cerasoli_2005_Chem.Biol.Interact_157-158_363
Author(s) : Cerasoli DM , Griffiths EM , Doctor BP , Saxena A , Fedorko JM , Greig NH , Yu QS , Huang Y , Wilgus H , Karatzas CN , Koplovitz I , Lenz DE
Ref : Chemico-Biological Interactions , 157-158 :363 , 2005
Abstract :
PubMedSearch : Cerasoli_2005_Chem.Biol.Interact_157-158_363
PubMedID: 16429486

Title : Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents - Nambiar_2005_Chem.Biol.Interact_157-158_409
Author(s) : Nambiar MP , Curtin BF , Pal N , Compton JR , Doctor BP , Gordon RK
Ref : Chemico-Biological Interactions , 157-158 :409 , 2005
Abstract :
PubMedSearch : Nambiar_2005_Chem.Biol.Interact_157-158_409
PubMedID: 16429504

Title : An ex vivo approach for the evaluation of reversible inhibitors as potential pretreatments against organophosphate toxicity - Tonduli_2005_Chem.Biol.Interact_157-158_426
Author(s) : Tonduli LS , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :426 , 2005
Abstract :
PubMedSearch : Tonduli_2005_Chem.Biol.Interact_157-158_426
PubMedID: 16429574

Title : Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure - Curtin_2005_J.Cell.Biochem_96_839
Author(s) : Curtin BF , Tetz LM , Compton JR , Doctor BP , Gordon RK , Nambiar MP
Ref : Journal of Cellular Biochemistry , 96 :839 , 2005
Abstract :
PubMedSearch : Curtin_2005_J.Cell.Biochem_96_839
PubMedID: 16149071

Title : Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys - Lenz_2005_Chem.Biol.Interact_157-158_205
Author(s) : Lenz DE , Maxwell DM , Koplovitz I , Clark CR , Capacio BR , Cerasoli DM , Federko JM , Luo C , Saxena A , Doctor BP , Olson C
Ref : Chemico-Biological Interactions , 157-158 :205 , 2005
Abstract :
PubMedSearch : Lenz_2005_Chem.Biol.Interact_157-158_205
PubMedID: 16289064

Title : Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases -
Author(s) : Luo C , Dawson M , Chambers C , Chilukuri N , Radic Z , Taylor P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :393 , 2005
PubMedID: 16429528

Title : Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity -
Author(s) : Haigh JR , Johnston SR , Peters BM , Doctor BP , Gordon RK , Adler M , Gall KJ , Deshpande SS
Ref : Chemico-Biological Interactions , 157-158 :381 , 2005
PubMedID: 16429510

Title : Interaction of beta-amyloid and cholinesterases by fluorescent polarization -
Author(s) : Nigam SV , Doctor BP , Gordon RK
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :171 , 2004
PubMedID:

Title : Poster (15) Molecular recognition in AChE catalysis - the view from near and far. -
Author(s) : Moussavi-Harami F , Sikorski RS , Quinn DM , Feaster SR , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :328 , 2004
PubMedID:

Title : Detection and identification of chemical warfare Agents polyurethane immobilized enzymes -
Author(s) : Gordon RK , Gunduz AT , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :243 , 2004
PubMedID:

Title : Strategy for reactivation of organophosphate-inhibited human butyrylcholinesterase -
Author(s) : Luo C , Dawson M , Maxwell DM , Doctor BP , Saxena A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :251 , 2004
PubMedID:

Title : Human serum butyrylcholinesterase: A future generation antidote for organophosphate chemical warfare agent toxicity . -
Author(s) : Saxena A , Luo C , Bansal R , Sun W , Clark M , Ashani Y , Ross M , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :269 , 2004
PubMedID:

Title : Poster (30) Detection and identification of chemical warfare agents polyurethane immobilized enzymes -
Author(s) : Gordon RK , Gunduz AT , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :336 , 2004
PubMedID:

Title : Poster (32) Bioscavengers: antidotes for organophosphate chemical warfare agent toxicity. -
Author(s) : Doctor BP , Saxena A , Ashani Y , Ross M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :337 , 2004
PubMedID:

Title : Poster (33) Strategy for the reactivation of organophosphate-inhibited human butyrylcholinesterase -
Author(s) : Luo C , McKissic D , Doctor BP , Saxena A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :338 , 2004
PubMedID:

Title : Poster (36) Human serum butyrylcholinesterase: a future generation antidote for organophosphate chemical warfare agent toxicity -
Author(s) : Saxena A , Luo C , Bansal R , Sun W , Clark M , Ashani Y , Ross M , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :339 , 2004
PubMedID:

Title : Protective effect of equine butyrylcholinesterase in inhalation intoxication of rats with sarin: determination of blood and brain cholinesterase activities - Sevelova_2004_Inhal.Toxicol_16_531
Author(s) : Sevelova L , Bajgar J , Saxena A , Doctor BP
Ref : Inhal Toxicol , 16 :531 , 2004
Abstract :
PubMedSearch : Sevelova_2004_Inhal.Toxicol_16_531
PubMedID: 15204744

Title : Polyurethane immobilized enzymes. -
Author(s) : Gordon RK , Gunduz AT , Doctor BP , Cronin T
Ref : Cholinergic Mechanisms, CRC Press :265 , 2004
PubMedID:

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. -
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Cholinergic Mechanisms, CRC Press :627 , 2004
PubMedID:

Title : Poster (81) Interaction of beta-amyloid and cholinesterases by fluorescent polarization -
Author(s) : Nigam SV , Doctor BP , Gordon RK
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :363 , 2004
PubMedID:

Title : The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study - Gabel_2004_Biophys.J_86_3152
Author(s) : Gabel F , Weik M , Doctor BP , Saxena A , Fournier D , Brochier L , Renault F , Masson P , Silman I , Zaccai G
Ref : Biophysical Journal , 86 :3152 , 2004
Abstract :
PubMedSearch : Gabel_2004_Biophys.J_86_3152
PubMedID: 15111428

Title : Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators - Ashani_2003_Biochem.Pharmacol_66_191
Author(s) : Ashani Y , Bhattacharjee AK , Leader H , Saxena A , Doctor BP
Ref : Biochemical Pharmacology , 66 :191 , 2003
Abstract :
PubMedSearch : Ashani_2003_Biochem.Pharmacol_66_191
PubMedID: 12826262

Title : Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases - Saxena_2003_Eur.J.Biochem_270_4447
Author(s) : Saxena A , Fedorko JM , Vinayaka CR , Medhekar R , Radic Z , Taylor P , Lockridge O , Doctor BP
Ref : European Journal of Biochemistry , 270 :4447 , 2003
Abstract :
PubMedSearch : Saxena_2003_Eur.J.Biochem_270_4447
PubMedID: 14622273

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase - Luo_2003_Biochem.Pharmacol_66_387
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Biochemical Pharmacology , 66 :387 , 2003
Abstract :
PubMedSearch : Luo_2003_Biochem.Pharmacol_66_387
PubMedID: 12907237

Title : Natural monomeric form of fetal bovine serum acetylcholinesterase lacks the C-terminal tetramerization domain - Saxena_2003_Biochemistry_42_15292
Author(s) : Saxena A , Hur RS , Luo C , Doctor BP
Ref : Biochemistry , 42 :15292 , 2003
Abstract :
PubMedSearch : Saxena_2003_Biochemistry_42_15292
PubMedID: 14690439

Title : Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B - Rajendran_2002_Bioorg.Med.Chem.Lett_12_1521
Author(s) : Rajendran V , Saxena A , Doctor BP , Kozikowski AP
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :1521 , 2002
Abstract :
PubMedSearch : Rajendran_2002_Bioorg.Med.Chem.Lett_12_1521
PubMedID: 12031333

Title : Pharmacokinetics and immunologic consequences of exposing macaques to purified homologous butyrylcholinesterase - Rosenberg_2002_Life.Sci_72_125
Author(s) : Rosenberg YJ , Luo C , Ashani Y , Doctor BP , Fischer R , Wolfe G , Saxena A
Ref : Life Sciences , 72 :125 , 2002
Abstract :
PubMedSearch : Rosenberg_2002_Life.Sci_72_125
PubMedID: 12417246

Title : The NMDA receptor ion channel: a site for binding of Huperzine A - Gordon_2001_J.Appl.Toxicol_21 Suppl 1_S47
Author(s) : Gordon RK , Nigam SV , Weitz JA , Dave JR , Doctor BP , Ved HS
Ref : J Appl Toxicol , 21 Suppl 1 :S47 , 2001
Abstract :
PubMedSearch : Gordon_2001_J.Appl.Toxicol_21 Suppl 1_S47
PubMedID: 11920920

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
Abstract :
PubMedSearch : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedID: 10421446

Title : Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1999_Chem.Biol.Interact_119-120_61
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :61 , 1999
Abstract :
PubMedSearch : Saxena_1999_Chem.Biol.Interact_119-120_61
PubMedID: 10421439

Title : Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases - Maxwell_1999_Chem.Biol.Interact_119-120_419
Author(s) : Maxwell DM , Saxena A , Gordon RK , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :419 , 1999
Abstract :
PubMedSearch : Maxwell_1999_Chem.Biol.Interact_119-120_419
PubMedID: 10421479

Title : Organophosphate skin decontamination using immobilized enzymes - Gordon_1999_Chem.Biol.Interact_119-120_463
Author(s) : Gordon RK , Feaster SR , Russell AJ , LeJeune KE , Maxwell DM , Lenz DE , Ross M , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :463 , 1999
Abstract :
PubMedSearch : Gordon_1999_Chem.Biol.Interact_119-120_463
PubMedID: 10421484

Title : Allosteric control of acetylcholinesterase activity by monoclonal antibodies -
Author(s) : Saxena A , Hur RS , Doctor BP
Ref : Biochemistry , 38 :15688 , 1999
PubMedID: 10569956

Title : Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium - Luo_1999_Biochemistry_38_9937
Author(s) : Luo C , Saxena A , Smith M , Garcia GE , Radic Z , Taylor P , Doctor BP
Ref : Biochemistry , 38 :9937 , 1999
Abstract :
PubMedSearch : Luo_1999_Biochemistry_38_9937
PubMedID: 10433700

Title : A Comparison of Blood Cholinesterase Activities, Pyridostigmine Inhibition of Red Cell Acetylcholinesterase, and Butyrylcholinesterase Phenotypes in Gulf War Veterans and Normal Controls -
Author(s) : Gentry MK , Powell S , Bitsko N , Bartels CF , Bartko J , Chung R , Lockridge O , Ribas J , Roy M , Malone J , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :300 , 1998
PubMedID:

Title : Synthesis and anticholinesterase activity of huperzine A analogues containing phenol and catechol replacements for the pyridone ring - Campiani_1998_Bioorg.Med.Chem.Lett_8_1413
Author(s) : Campiani G , Kozikowski AP , Wang S , Ming L , Nacci V , Saxena A , Doctor BP
Ref : Bioorganic & Medicinal Chemistry Lett , 8 :1413 , 1998
Abstract :
PubMedSearch : Campiani_1998_Bioorg.Med.Chem.Lett_8_1413
PubMedID: 9871776

Title : Stable Complexes Involving Acetylcholinesterase and Amyloid-beta Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer's Fibrils - Alvarez_1998_J.Neurosci_18_3213
Author(s) : Alvarez A , Alarcon R , Opazo C , Campos EO , Munoz FJ , Calderon FH , Dajas F , Gentry MK , Doctor BP , de Mello FG , Inestrosa NC
Ref : Journal of Neuroscience , 18 :3213 , 1998
Abstract :
PubMedSearch : Alvarez_1998_J.Neurosci_18_3213
PubMedID: 9547230

Title : pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants -
Author(s) : Viragh C , Saxena A , Frazier DS , Kovach IM , Lockridge O , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :247 , 1998
PubMedID:

Title : Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Fetal Bovine Serum Acetylcholinesterase by Monoquaternary and Bisquaternary Ligands - Luo_1998_Mol.Pharmacol_53_718
Author(s) : Luo C , Ashani Y , Doctor BP
Ref : Molecular Pharmacology , 53 :718 , 1998
Abstract :
PubMedSearch : Luo_1998_Mol.Pharmacol_53_718
PubMedID: 9547363

Title : Amino Acid Sequence of Horse Serum Butyrylcholinesterase -
Author(s) : Moorad DR , Luo C , Saxena A , Doctor BP , Garcia GE
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :145 , 1998
PubMedID:
Gene_locus related to this paper: horse-BCHE

Title : Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon - Amitai_1998_Biochem.Pharmacol_56_293
Author(s) : Amitai G , Moorad DR , Adani R , Doctor BP
Ref : Biochemical Pharmacology , 56 :293 , 1998
Abstract :
PubMedSearch : Amitai_1998_Biochem.Pharmacol_56_293
PubMedID: 9744565

Title : The Role of Oligosaccharides in the Pharmacokinetics of Cholinesterases -
Author(s) : Saxena A , Ashani Y , Raveh L , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :283 , 1998
PubMedID:

Title : Acceleration of oxime-induced reactivation of acetylcholinesterase-organophosphate conjugate and 31P NMR detection of phosporyl oxime from the conjugate -
Author(s) : Luo C , Ashani Y , Doctor BP
Ref : Journal de Physiologie (Paris) , 92 :461 , 1998
PubMedID:

Title : Characterization of ChEs Immobilized on Polyurethane Foams -
Author(s) : Gordon RK , Feaster SR , Herron PC II , Lowe ER , LeJeune KE , Russell AJ , Lenz DE , Ross M , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :307 , 1998
PubMedID:

Title : Allosteric control of acetylcholinesterase activity by monoclonal antibodies - Saxena_1998_Biochemistry_37_145
Author(s) : Saxena A , Hur RS , Doctor BP
Ref : Biochemistry , 37 :145 , 1998
Abstract :
PubMedSearch : Saxena_1998_Biochemistry_37_145
PubMedID: 9425034

Title : The pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants: Further Evidence for a Push-Pull Mechanism - Saxena_1998_Biochemistry_37_15086
Author(s) : Saxena A , Viragh C , Frazier DS , Kovach IM , Maxwell DM , Lockridge O , Doctor BP
Ref : Biochemistry , 37 :15086 , 1998
Abstract :
PubMedSearch : Saxena_1998_Biochemistry_37_15086
PubMedID: 9790671

Title : Comparison of Cholinesterases and Carboxylesterase as Bioscavengers for Organophosphorus Compounds -
Author(s) : Maxwell DM , Brecht KM , Saxena A , Feaster SR , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :387 , 1998
PubMedID:

Title : Role of oligosaccharides in the pharmacokinetics of tissue-derived and genetically engineered cholinesterases - Saxena_1998_Mol.Pharmacol_53_112
Author(s) : Saxena A , Ashani Y , Raveh L , Stevenson D , Patel T , Doctor BP
Ref : Molecular Pharmacology , 53 :112 , 1998
Abstract :
PubMedSearch : Saxena_1998_Mol.Pharmacol_53_112
PubMedID: 9443938

Title : Comparative Effects of Cholinesterase Inhibitors on Glutamate-Induced Neuronal Cell Death -
Author(s) : Ved HS , Dave JR , Nguyen T , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :181 , 1998
PubMedID:

Title : Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Acetylcholinesterase by Quaternary Ligands -
Author(s) : Luo C , Ashani Y , Saxena A , Leader H , Maxwell DM , Taylor P , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :215 , 1998
PubMedID:

Title : Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1997_Biochemistry_36_14642
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Biochemistry , 36 :14642 , 1997
Abstract :
PubMedSearch : Saxena_1997_Biochemistry_36_14642
PubMedID: 9398183

Title : A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme - Reyes_1997_Biochem.Biophys.Res.Commun_232_652
Author(s) : Reyes AE , Perez DR , Alvarez A , Garrido J , Gentry MK , Doctor BP , Inestrosa NC
Ref : Biochemical & Biophysical Research Communications , 232 :652 , 1997
Abstract :
PubMedSearch : Reyes_1997_Biochem.Biophys.Res.Commun_232_652
PubMedID: 9126330

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
Abstract :
PubMedSearch : Saxena_1997_Biochem.Pharmacol_54_269
PubMedID: 9271331

Title : Structure of glycan moieties responsible for the extended circulatory life time of fetal bovine serum acetylcholinesterase and equine serum butyrylcholinesterase - Saxena_1997_Biochemistry_36_7481
Author(s) : Saxena A , Raveh L , Ashani Y , Doctor BP
Ref : Biochemistry , 36 :7481 , 1997
Abstract :
PubMedSearch : Saxena_1997_Biochemistry_36_7481
PubMedID: 9200697

Title : Horse Serum Butyrylcholinesterase Does Not Disrupt Passive Avoidance Learning or Spontaneous Motor Activity in Rats -
Author(s) : Genovese RF , Roberts AR , Fantegrossi WE , Larrison RW , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :473 , 1995
PubMedID:

Title : Comparative Inhibition of Acetylcholinesterase by Tacrine, Physostigmine and Huperzine in the Adult Rat Brain -
Author(s) : Ved HS , Best JM , Dave JR , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :477 , 1995
PubMedID:

Title : Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes - Ashani_1995_J.Biol.Chem_270_6370
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : Journal of Biological Chemistry , 270 :6370 , 1995
Abstract :
PubMedSearch : Ashani_1995_J.Biol.Chem_270_6370
PubMedID: 7890775

Title : Amino Acid Alignment of Cholinesterases, Esterases, Lipases, and Related Proteins -
Author(s) : Gentry MK , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :493 , 1995
PubMedID:

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Behavioral and pharmacological assessment of butyrylcholinesterase in rats - Genovese_1995_Pharmacol.Biochem.Behav_51_647
Author(s) : Genovese RF , Doctor BP
Ref : Pharmacology, Biochemistry & Behavior , 51 :647 , 1995
Abstract :
PubMedSearch : Genovese_1995_Pharmacol.Biochem.Behav_51_647
PubMedID: 7675838

Title : Comparison of Acetylcholinesterase, Pyridostigmine, and HI-6 as Antidotes against Organophosphorus Compounds -
Author(s) : Maxwell DM , Brecht KM , Saxena A , Taylor P , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :353 , 1995
PubMedID:

Title : Structural Analysis of the Asparagine-Linked Oligosaccharides of Cholinesterases -
Author(s) : Saxena A , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :105 , 1995
PubMedID:

Title : Alterations in the Topography of Acetylcholinesterase Active Site Gorge after Binding of Peripheral Anionic Site Ligands -
Author(s) : Stalc A , Grubic Z , Sentjurc M , Pecar S , Gentry MK , Doctor BP
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :125 , 1995
PubMedID:

Title : Modulation of Catalysis and Inhibition of Fetal Bovine Serum Acetylcholinesterase by Monoclonal Antibodies -
Author(s) : Doctor BP , Gentry MK , Saxena A , Ashani Y
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :141 , 1995
PubMedID:

Title : Characterization of monoclonal antibodies that inhibit the catalytic activity of acetylcholinesterases - Gentry_1995_J.Neurochem_64_842
Author(s) : Gentry MK , Moorad DR , Hur RS , Saxena A , Ashani Y , Doctor BP
Ref : Journal of Neurochemistry , 64 :842 , 1995
Abstract :
PubMedSearch : Gentry_1995_J.Neurochem_64_842
PubMedID: 7830078

Title : Reversal of Glycerol Ether-Stimulated Acetylcholinesterase Activity by c-fos Antisense Oligonucleotide in Primary Neuronal Cultures -
Author(s) : Dave JR , Fasnacht E , Tortella FC , Best JM , Doctor BP , Ved HS
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :289 , 1995
PubMedID:

Title : Different effects of two peripheral anionic site-binding ligands on acetylcholinesterase active-site gorge topography revealed by electron paramagnetic resonance - Grubic_1995_Biochim.Biophys.Acta_1249_155
Author(s) : Grubic Z , Stalc A , Sentjurc M , Pecar S , Gentry MK , Doctor BP
Ref : Biochimica & Biophysica Acta , 1249 :155 , 1995
Abstract :
PubMedSearch : Grubic_1995_Biochim.Biophys.Acta_1249_155
PubMedID: 7599168

Title : Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes - Caranto_1994_Biochem.Pharmacol_47_347
Author(s) : Caranto GR , Waibel KH , Asher JM , Larrison RW , Brecht KM , Schutz MB , Raveh L , Ashani Y , Wolfe AD , Maxwell DM , Doctor BP
Ref : Biochemical Pharmacology , 47 :347 , 1994
Abstract :
PubMedSearch : Caranto_1994_Biochem.Pharmacol_47_347
PubMedID: 8304979

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
Abstract :
PubMedSearch : Saxena_1994_Protein.Sci_3_1770
PubMedID: 7849595

Title : Huperzine A as a pretreatment candidate drug against nerve agent toxicity - Grunwald_1994_Life.Sci_54_991
Author(s) : Grunwald J , Raveh L , Doctor BP , Ashani Y
Ref : Life Sciences , 54 :991 , 1994
Abstract :
PubMedSearch : Grunwald_1994_Life.Sci_54_991
PubMedID: 8139389

Title : Cholinesterases as scavengers for organophosphorus compounds: protection of primate performance against soman toxicity - Doctor_1993_Chem.Biol.Interact_87_285
Author(s) : Doctor BP , Blick DW , Caranto G , Castro CA , Gentry MK , Larrison RW , Maxwell DM , Murphy MR , Schutz MB , Waibel KH , Wolfe AD
Ref : Chemico-Biological Interactions , 87 :285 , 1993
Abstract :
PubMedSearch : Doctor_1993_Chem.Biol.Interact_87_285
PubMedID: 8343986

Title : Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins - Cygler_1993_Protein.Sci_2_366
Author(s) : Cygler M , Schrag JD , Sussman JL , Harel M , Silman I , Gentry MK , Doctor BP
Ref : Protein Science , 2 :366 , 1993
Abstract :
PubMedSearch : Cygler_1993_Protein.Sci_2_366
PubMedID: 8453375

Title : The role of glutamate-199 in the aging of cholinesterase - Saxena_1993_Biochem.Biophys.Res.Commun_197_343
Author(s) : Saxena A , Doctor BP , Maxwell DM , Lenz DE , Radic Z , Taylor P
Ref : Biochemical & Biophysical Research Communications , 197 :343 , 1993
Abstract :
PubMedSearch : Saxena_1993_Biochem.Biophys.Res.Commun_197_343
PubMedID: 7902714

Title : Epitope mapping of form-specific and nonspecific antibodies to acetylcholinesterase - Wasserman_1993_J.Neurochem_61_2124
Author(s) : Wasserman L , Doctor BP , Gentry MK , Taylor P
Ref : Journal of Neurochemistry , 61 :2124 , 1993
Abstract :
PubMedSearch : Wasserman_1993_J.Neurochem_61_2124
PubMedID: 7504082

Title : Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies - Gentry_1993_Chem.Biol.Interact_87_227
Author(s) : Gentry MK , Saxena A , Ashani Y , Doctor BP
Ref : Chemico-Biological Interactions , 87 :227 , 1993
Abstract :
PubMedSearch : Gentry_1993_Chem.Biol.Interact_87_227
PubMedID: 7688272

Title : Comparison of antidote protection against soman by pyridostigmine, HI-6 and acetylcholinesterase - Maxwell_1993_J.Pharmacol.Exp.Ther_264_1085
Author(s) : Maxwell DM , Brecht KM , Doctor BP , Wolfe AD
Ref : Journal of Pharmacology & Experimental Therapeutics , 264 :1085 , 1993
Abstract :
PubMedSearch : Maxwell_1993_J.Pharmacol.Exp.Ther_264_1085
PubMedID: 8450452

Title : Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy - Segall_1993_Biochemistry_32_13441
Author(s) : Segall Y , Waysbort D , Barak D , Ariel N , Doctor BP , Grunwald J , Ashani Y
Ref : Biochemistry , 32 :13441 , 1993
Abstract :
PubMedSearch : Segall_1993_Biochemistry_32_13441
PubMedID: 8257680

Title : Monoclonal antibody AE-2 modulates carbamate and organophosphate inhibition of fetal bovine serum acetylcholinesterase - Wolfe_1993_Mol.Pharmacol_44_1152
Author(s) : Wolfe AD , Chiang PK , Doctor BP , Fryar N , Rhee JP , Saeed M
Ref : Molecular Pharmacology , 44 :1152 , 1993
Abstract :
PubMedSearch : Wolfe_1993_Mol.Pharmacol_44_1152
PubMedID: 8264551

Title : Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity - Wolfe_1992_Toxicol.Appl.Pharmacol_117_189
Author(s) : Wolfe AD , Blick DW , Murphy MR , Miller SA , Gentry MK , Hartgraves SL , Doctor BP
Ref : Toxicology & Applied Pharmacology , 117 :189 , 1992
Abstract :
PubMedSearch : Wolfe_1992_Toxicol.Appl.Pharmacol_117_189
PubMedID: 1471150

Title : Membrane-bound acetylcholinesterase: an early differentiation marker for skeletal myoblasts - Elson_1992_Biochim.Biophys.Acta_1156_78
Author(s) : Elson HF , Gentry MK , Doctor BP
Ref : Biochimica & Biophysica Acta , 1156 :78 , 1992
Abstract :
PubMedSearch : Elson_1992_Biochim.Biophys.Acta_1156_78
PubMedID: 1472543

Title : Acetylcholinesterase: A Pretreatment Drug for Organophosphate Toxicity -
Author(s) : Doctor BP , Blick DW
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :277 , 1992
PubMedID:

Title : Mechanism of inhibition of cholinesterases by huperzine A - Ashani_1992_Biochem.Biophys.Res.Commun_184_719
Author(s) : Ashani Y , Peggins JO, 3rd , Doctor BP
Ref : Biochemical & Biophysical Research Communications , 184 :719 , 1992
Abstract :
PubMedSearch : Ashani_1992_Biochem.Biophys.Res.Commun_184_719
PubMedID: 1575745

Title : Protection of rhesus monkeys against soman and prevention of performance decrement by pretreatment with acetylcholinesterase - Maxwell_1992_Toxicol.Appl.Pharmacol_115_44
Author(s) : Maxwell DM , Castro CA , De La Hoz DM , Gentry MK , Gold MB , Solana RP , Wolfe AD , Doctor BP
Ref : Toxicology & Applied Pharmacology , 115 :44 , 1992
Abstract :
PubMedSearch : Maxwell_1992_Toxicol.Appl.Pharmacol_115_44
PubMedID: 1631892

Title : A microtiter assay for determining protein, acetylcholinesterase activity, and G418 (Neomycin) resistance in cultured cells - Elson_1992_Anal.Biochem_200_268
Author(s) : Elson HF , Gentry MK , Doctor BP
Ref : Analytical Biochemistry , 200 :268 , 1992
Abstract :
PubMedSearch : Elson_1992_Anal.Biochem_200_268
PubMedID: 1378703

Title : Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice - Ashani_1991_Biochem.Pharmacol_41_37
Author(s) : Ashani Y , Shapira S , Levy D , Wolfe AD , Doctor BP , Raveh L
Ref : Biochemical Pharmacology , 41 :37 , 1991
Abstract :
PubMedSearch : Ashani_1991_Biochem.Pharmacol_41_37
PubMedID: 1986743

Title : Bovine Brain Acetylcholinesterase Sequence Involved in Intersubunit Disulfide Linkages -
Author(s) : Rosenberry TL , Roberts WL , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :17 , 1991
PubMedID:

Title : Fetal Bovine Serum Acetylcholinesterase: Structure-Function Correlation -
Author(s) : Doctor BP , Gentry MK , Wu SJ , Ashani Y , De La Hoz DM
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :37 , 1991
PubMedID:

Title : Enzymes as pretreatment drugs for organophosphate toxicity - Doctor_1991_Neurosci.Biobehav.Rev_15_123
Author(s) : Doctor BP , Raveh L , Wolfe AD , Maxwell DM , Ashani Y
Ref : Neurosci Biobehav Rev , 15 :123 , 1991
Abstract :
PubMedSearch : Doctor_1991_Neurosci.Biobehav.Rev_15_123
PubMedID: 2052184

Title : Bovine brain acetylcholinesterase primary sequence involved in intersubunit disulfide linkages - Roberts_1991_J.Biol.Chem_266_7481
Author(s) : Roberts WL , Doctor BP , Foster JD , Rosenberry TL
Ref : Journal of Biological Chemistry , 266 :7481 , 1991
Abstract :
PubMedSearch : Roberts_1991_J.Biol.Chem_266_7481
PubMedID: 2019579

Title : Cholinesterase and Carboxyl esterase as Scavengers for Organophosphorus Agents -
Author(s) : Maxwell DM , Wolfe AD , Ashani Y , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :206 , 1991
PubMedID:

Title : Changes in the Catalytic Activity of Acetylcholinesterase upon Complexation with Monoclonal Antibodies -
Author(s) : Ashani Y , Bromberg A , Levy D , Gentry MK , Brady DR , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :235 , 1991
PubMedID:

Title : APPENDIX Alignment of Amino Acid Sequences of Acetylcholinesterases and Butyrylcholinesterases -
Author(s) : Gentry MK , Doctor BP
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :394 , 1991
PubMedID:

Title : Poster: Esterases as organophosphate scavengers -
Author(s) : Wolfe AD , Ashani Y , Doctor BP , Maxwell DM
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :306 , 1991
PubMedID:

Title : Studies on the topography of the catalytic site of acetylcholinesterase using polyclonal and monoclonal antibodies - Ogert_1990_J.Neurochem_55_756
Author(s) : Ogert RA , Gentry MK , Richardson EC , Deal CD , Abramson SN , Alving CR , Taylor P , Doctor BP
Ref : Journal of Neurochemistry , 55 :756 , 1990
Abstract :
PubMedSearch : Ogert_1990_J.Neurochem_55_756
PubMedID: 1696619

Title : Complete amino acid sequence of fetal bovine serum acetylcholinesterase and its comparison in various regions with other cholinesterases - Doctor_1990_FEBS.Lett_266_123
Author(s) : Doctor BP , Chapman TC , Christner CE , Deal CD , De La Hoz DM , Gentry MK , Ogert RA , Rush RS , Smyth KK , Wolfe AD
Ref : FEBS Letters , 266 :123 , 1990
Abstract :
PubMedSearch : Doctor_1990_FEBS.Lett_266_123
PubMedID: 2365060
Gene_locus related to this paper: bovin-ACHE

Title : Differences in conformational stability between native and phosphorylated acetylcholinesterase as evidenced by a monoclonal antibody - Ashani_1990_Biochemistry_29_2456
Author(s) : Ashani Y , Gentry MK , Doctor BP
Ref : Biochemistry , 29 :2456 , 1990
Abstract :
PubMedSearch : Ashani_1990_Biochemistry_29_2456
PubMedID: 1692236

Title : Differences in structure and distribution of the molecular forms of acetylcholinesterase - Abramson_1989_J.Cell.Biol_108_2301
Author(s) : Abramson SN , Ellisman MH , Deerinck TJ , Maulet Y , Gentry MK , Doctor BP , Taylor P
Ref : Journal of Cell Biology , 108 :2301 , 1989
Abstract :
PubMedSearch : Abramson_1989_J.Cell.Biol_108_2301
PubMedID: 2472404

Title : Acetylcholinesterase prophylaxis against organophosphate poisoning. Quantitative correlation between protection and blood-enzyme level in mice - Raveh_1989_Biochem.Pharmacol_38_529
Author(s) : Raveh L , Ashani Y , Levy D , De La Hoz DM , Wolfe AD , Doctor BP
Ref : Biochemical Pharmacology , 38 :529 , 1989
Abstract :
PubMedSearch : Raveh_1989_Biochem.Pharmacol_38_529
PubMedID: 2917010

Title : Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates - Leader_1989_J.Med.Chem_32_1522
Author(s) : Leader H , Smejkal RM , Payne CS , Padilla FN , Doctor BP , Gordon RK , Chiang PK
Ref : Journal of Medicinal Chemistry , 32 :1522 , 1989
Abstract :
PubMedSearch : Leader_1989_J.Med.Chem_32_1522
PubMedID: 2738887

Title : Structural and immunochemical properties of fetal bovine serum acetylcholinesterase -
Author(s) : Doctor BP , Smyth KK , Gentry MK , Ashani Y , Christner CE , De La Hoz DM , Ogert RA , Smith SW
Ref : Progress in Clinical & Biological Research , 289 :305 , 1989
PubMedID: 2471207

Title : Desethylaprophen: a metabolite of aprophen with antimuscarinic activities - Brown_1988_J.Pharm.Sci_77_145
Author(s) : Brown ND , Smejkal RM , Breuer E , Doctor BP , Chiang PK
Ref : J Pharm Sci , 77 :145 , 1988
Abstract :
PubMedSearch : Brown_1988_J.Pharm.Sci_77_145
PubMedID: 3258910

Title : Acetylcholinesterase prophylaxis against organophosphate toxicity - Wolfe_1987_Fundam.Appl.Toxicol_9_266
Author(s) : Wolfe AD , Rush RS , Doctor BP , Koplovitz I , Jones D
Ref : Fundamental & Applied Toxicology , 9 :266 , 1987
Abstract :
PubMedSearch : Wolfe_1987_Fundam.Appl.Toxicol_9_266
PubMedID: 3653568

Title : Microtiter assay for acetylcholinesterase - Doctor_1987_Anal.Biochem_166_399
Author(s) : Doctor BP , Toker L , Roth E , Silman I
Ref : Analytical Biochemistry , 166 :399 , 1987
Abstract :
PubMedSearch : Doctor_1987_Anal.Biochem_166_399
PubMedID: 3434781

Title : Disposition of aprophen in rats - Aarbakke_1986_J.Pharm.Pharmacol_38_928
Author(s) : Aarbakke J , Miura GA , Brown ND , Gray RR , Gordon RK , Doctor BP , Chiang PK
Ref : J Pharm Pharmacol , 38 :928 , 1986
Abstract :
PubMedSearch : Aarbakke_1986_J.Pharm.Pharmacol_38_928
PubMedID: 2880971

Title : A simplified procedure for the purification of large quantities of fetal bovine serum acetylcholinesterase - De La Hoz_1986_Life.Sci_39_195
Author(s) : De La Hoz DM , Doctor BP , Ralston JS , Rush RS , Wolfe AD
Ref : Life Sciences , 39 :195 , 1986
Abstract :
PubMedSearch : De La Hoz_1986_Life.Sci_39_195
PubMedID: 3736320

Title : Kinetic investigations into the interactions of aprophen with cholinesterases and a carboxylesterase - Rush_1986_Biochem.Pharmacol_35_4167
Author(s) : Rush RS , Doctor BP , Wolfe AD
Ref : Biochemical Pharmacology , 35 :4167 , 1986
Abstract :
PubMedSearch : Rush_1986_Biochem.Pharmacol_35_4167
PubMedID: 3098245

Title : Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine - Miura_1986_Gen.Pharmacol_17_477
Author(s) : Miura GA , Chiang PK , Gordon RK , Doctor BP , Twine CE , Philip A , Kepler JA , Carroll FI
Ref : General Pharmacology , 17 :477 , 1986
Abstract :
PubMedSearch : Miura_1986_Gen.Pharmacol_17_477
PubMedID: 2875921

Title : Acetylcholinesterase from fetal bovine serum. Purification and characterization of soluble G4 enzyme - Ralston_1985_J.Biol.Chem_260_4312
Author(s) : Ralston JS , Rush RS , Doctor BP , Wolfe AD
Ref : Journal of Biological Chemistry , 260 :4312 , 1985
Abstract :
PubMedSearch : Ralston_1985_J.Biol.Chem_260_4312
PubMedID: 3980478

Title : Molecular aspects of the biosynthesis and disposition of multiple forms of acetylcholinesterase -
Author(s) : Taylor P , Camp S , Lee SL , Amitai G , Taylor SS , Doctor BP
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :145 , 1984
PubMedID:

Title : Stability study of HI-6 dichloride in various anticholinergic formulations -
Author(s) : Brown ND , Gray RR , Stermer-Cox MG , Doctor BP , Hagedorn I
Ref : Journal of Chromatography , 315 :389 , 1984
PubMedID: 6526905

Title : Poster 8. Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase -
Author(s) : Doctor BP , Taylor P
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984
PubMedID:

Title : Antimuscarinic activity of aprophen -
Author(s) : Gordon RK , Padilla FN , Moore E , Doctor BP , Chiang PK
Ref : Biochemical Pharmacology , 32 :2979 , 1983
PubMedID: 6626268

Title : Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase - Doctor_1983_Proc.Natl.Acad.Sci.U.S.A_80_5767
Author(s) : Doctor BP , Camp S , Gentry MK , Taylor SS , Taylor P
Ref : Proceedings of the National Academy of Sciences of the United States of America , 80 :5767 , 1983
Abstract :
PubMedSearch : Doctor_1983_Proc.Natl.Acad.Sci.U.S.A_80_5767
PubMedID: 6193524

Title : A radioactive assay for acetylcholinesterase using anion-exchange disk -
Author(s) : Gordon RK , Doctor BP , Chiang PK
Ref : Analytical Biochemistry , 124 :333 , 1982
PubMedID: 6756205

Title : Inhibition of ribonucleic acid degradation in bacteria by spermine -
Author(s) : Herbst EJ , Doctor BP
Ref : Journal of Biological Chemistry , 234 :1497 , 1959
PubMedID: 13654404