Carroll FI

General

Full name : Carroll Frank Ivy

First name : Frank Ivy

Mail : Center for Organic and Medicinal Chemistry, Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709

Zip Code :

City :

Country : USA

Email : fic@rti.org

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References (34)

Title : Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2'-Fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine Analogues - Ondachi_2014_J.Med.Chem_57_836
Author(s) : Ondachi PW , Castro AH , Bartkowiak JM , Luetje CW , Damaj MI , Mascarella SW , Navarro HA , Carroll FI
Ref : Journal of Medicinal Chemistry , 57 :836 , 2014
Abstract :
PubMedSearch : Ondachi_2014_J.Med.Chem_57_836
PubMedID: 24428686

Title : Nicotinic Receptor Agonists Reduce L-DOPA-Induced Dyskinesias in a Monkey Model of Parkinson's Disease - Zhang_2013_J.Pharmacol.Exp.Ther_347_225
Author(s) : Zhang D , Mallela A , Sohn D , Carroll FI , Bencherif M , Letchworth SR , Quik M
Ref : Journal of Pharmacology & Experimental Therapeutics , 347 :225 , 2013
Abstract :
PubMedSearch : Zhang_2013_J.Pharmacol.Exp.Ther_347_225
PubMedID: 23902940

Title : Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice - Jackson_2013_Psychopharmacology.(Berl)_226_763
Author(s) : Jackson KJ , McLaughlin JP , Carroll FI , Damaj MI
Ref : Psychopharmacology (Berl) , 226 :763 , 2013
Abstract :
PubMedSearch : Jackson_2013_Psychopharmacology.(Berl)_226_763
PubMedID: 22526543

Title : The antinociceptive effects of nicotinic receptors alpha7-positive allosteric modulators in murine acute and tonic pain models - Freitas_2013_J.Pharmacol.Exp.Ther_344_264
Author(s) : Freitas K , Carroll FI , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 344 :264 , 2013
Abstract :
PubMedSearch : Freitas_2013_J.Pharmacol.Exp.Ther_344_264
PubMedID: 23115222

Title : In vivo pharmacological interactions between a type II positive allosteric modulator of alpha7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model - Freitas_2013_Br.J.Pharmacol_169_567
Author(s) : Freitas K , Negus SS , Carroll FI , Damaj MI
Ref : British Journal of Pharmacology , 169 :567 , 2013
Abstract :
PubMedSearch : Freitas_2013_Br.J.Pharmacol_169_567
PubMedID: 23004024

Title : Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse - Grabus_2012_Nicotine.Tob.Res_14_1356
Author(s) : Grabus SD , Carroll FI , Damaj MI
Ref : Nicotine Tob Res , 14 :1356 , 2012
Abstract :
PubMedSearch : Grabus_2012_Nicotine.Tob.Res_14_1356
PubMedID: 22589419

Title : Effects of the specific alpha4beta2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice - Tobey_2012_Psychopharmacology.(Berl)_223_159
Author(s) : Tobey KM , Walentiny DM , Wiley JL , Carroll FI , Damaj MI , Azar MR , Koob GF , George O , Harris LS , Vann RE
Ref : Psychopharmacology (Berl) , 223 :159 , 2012
Abstract :
PubMedSearch : Tobey_2012_Psychopharmacology.(Berl)_223_159
PubMedID: 22526534

Title : Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine - Ondachi_2012_J.Med.Chem_55_6512
Author(s) : Ondachi P , Castro A , Luetje CW , Damaj MI , Mascarella SW , Navarro HA , Carroll FI
Ref : Journal of Medicinal Chemistry , 55 :6512 , 2012
Abstract :
PubMedSearch : Ondachi_2012_J.Med.Chem_55_6512
PubMedID: 22742586

Title : The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models - AlSharari_2012_J.Pharmacol.Exp.Ther_342_742
Author(s) : AlSharari SD , Carroll FI , McIntosh JM , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 342 :742 , 2012
Abstract :
PubMedSearch : AlSharari_2012_J.Pharmacol.Exp.Ther_342_742
PubMedID: 22678099

Title : Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration - George_2011_Psychopharmacology.(Berl)_213_715
Author(s) : George O , Lloyd A , Carroll FI , Damaj MI , Koob GF
Ref : Psychopharmacology (Berl) , 213 :715 , 2011
Abstract :
PubMedSearch : George_2011_Psychopharmacology.(Berl)_213_715
PubMedID: 20924754

Title : Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine - Carroll_2011_J.Med.Chem_54_1441
Author(s) : Carroll FI , Muresan AZ , Blough BE , Navarro HA , Mascarella SW , Eaton JB , Huang X , Damaj MI , Lukas RJ
Ref : Journal of Medicinal Chemistry , 54 :1441 , 2011
Abstract :
PubMedSearch : Carroll_2011_J.Med.Chem_54_1441
PubMedID: 21319801

Title : Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation - Lukas_2010_J.Med.Chem_53_4731
Author(s) : Lukas RJ , Muresan AZ , Damaj MI , Blough BE , Huang X , Navarro HA , Mascarella SW , Eaton JB , Marxer-Miller SK , Carroll FI
Ref : Journal of Medicinal Chemistry , 53 :4731 , 2010
Abstract :
PubMedSearch : Lukas_2010_J.Med.Chem_53_4731
PubMedID: 20509659

Title : Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice - Damaj_2010_J.Pharmacol.Exp.Ther_334_1087
Author(s) : Damaj MI , Grabus SD , Navarro HA , Vann RE , Warner JA , King LS , Wiley JL , Blough BE , Lukas RJ , Carroll FI
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :1087 , 2010
Abstract :
PubMedSearch : Damaj_2010_J.Pharmacol.Exp.Ther_334_1087
PubMedID: 20576796

Title : In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs - Abdrakhmanova_2010_Neuropharmacol_59_511
Author(s) : Abdrakhmanova GR , Blough BE , Nesloney C , Navarro HA , Damaj MI , Carroll FI
Ref : Neuropharmacology , 59 :511 , 2010
Abstract :
PubMedSearch : Abdrakhmanova_2010_Neuropharmacol_59_511
PubMedID: 20633568

Title : Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation - Carroll_2010_J.Med.Chem_53_2204
Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI
Ref : Journal of Medicinal Chemistry , 53 :2204 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Med.Chem_53_2204
PubMedID: 20158204

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists - Carroll_2010_J.Nat.Prod_73_306
Author(s) : Carroll FI , Ma W , Deng L , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Natural Products , 73 :306 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Nat.Prod_73_306
PubMedID: 20038125

Title : Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2beta-substituted tropanes - Carroll_2010_J.Med.Chem_53_8345
Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI
Ref : Journal of Medicinal Chemistry , 53 :8345 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Med.Chem_53_8345
PubMedID: 21058665

Title : Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse - Jackson_2010_Psychopharmacology.(Berl)_210_285
Author(s) : Jackson KJ , Carroll FI , Negus SS , Damaj MI
Ref : Psychopharmacology (Berl) , 210 :285 , 2010
Abstract :
PubMedSearch : Jackson_2010_Psychopharmacology.(Berl)_210_285
PubMedID: 20232057

Title : Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats - LeSage_2009_Pharmacol.Biochem.Behav_91_461
Author(s) : LeSage MG , Shelley D , Ross JT , Carroll FI , Corrigall WA
Ref : Pharmacol Biochem Behav , 91 :461 , 2009
Abstract :
PubMedSearch : LeSage_2009_Pharmacol.Biochem.Behav_91_461
PubMedID: 18817808

Title : 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs - Abdrakhmanova_2008_Neuropharmacol_55_1287
Author(s) : Abdrakhmanova GR , Carroll FI , Damaj MI , Martin BR
Ref : Neuropharmacology , 55 :1287 , 2008
Abstract :
PubMedSearch : Abdrakhmanova_2008_Neuropharmacol_55_1287
PubMedID: 18775444

Title : Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine - Carroll_2007_J.Med.Chem_50_6383
Author(s) : Carroll FI , Robinson TP , Brieaddy LE , Atkinson RN , Mascarella SW , Damaj MI , Martin BR , Navarro HA
Ref : Journal of Medicinal Chemistry , 50 :6383 , 2007
Abstract :
PubMedSearch : Carroll_2007_J.Med.Chem_50_6383
PubMedID: 17994682

Title : 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs - Abdrakhmanova_2006_Mol.Pharmacol_69_1945
Author(s) : Abdrakhmanova GR , Damaj MI , Carroll FI , Martin BR
Ref : Molecular Pharmacology , 69 :1945 , 2006
Abstract :
PubMedSearch : Abdrakhmanova_2006_Mol.Pharmacol_69_1945
PubMedID: 16505153

Title : Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes - Carroll_2006_J.Med.Chem_49_3244
Author(s) : Carroll FI , Hu X , Navarro HA , Deschamps J , Abdrakhmanova GR , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 49 :3244 , 2006
Abstract :
PubMedSearch : Carroll_2006_J.Med.Chem_49_3244
PubMedID: 16722642

Title : Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues - Carroll_2005_J.Med.Chem_48_7491
Author(s) : Carroll FI , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 48 :7491 , 2005
Abstract :
PubMedSearch : Carroll_2005_J.Med.Chem_48_7491
PubMedID: 16279810

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists - Carroll_2005_J.Med.Chem_48_1221
Author(s) : Carroll FI , Ma W , Yokota Y , Lee JR , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 48 :1221 , 2005
Abstract :
PubMedSearch : Carroll_2005_J.Med.Chem_48_1221
PubMedID: 15715488

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist - Carroll_2004_J.Med.Chem_47_4588
Author(s) : Carroll FI , Ware R , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 47 :4588 , 2004
Abstract :
PubMedSearch : Carroll_2004_J.Med.Chem_47_4588
PubMedID: 15317468

Title : Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors - Damaj_2004_Mol.Pharmacol_66_675
Author(s) : Damaj MI , Carroll FI , Eaton JB , Navarro HA , Blough BE , Mirza S , Lukas RJ , Martin BR
Ref : Molecular Pharmacology , 66 :675 , 2004
Abstract :
PubMedSearch : Damaj_2004_Mol.Pharmacol_66_675
PubMedID: 15322260

Title : Reversing the action of noncompetitive inhibitors (MK-801 and cocaine) on a protein (nicotinic acetylcholine receptor)-mediated reaction - Hess_2003_Biochemistry_42_6106
Author(s) : Hess GP , Gameiro AM , Schoenfeld RC , Chen Y , Ulrich H , Nye JA , Sit B , Carroll FI , Ganem B
Ref : Biochemistry , 42 :6106 , 2003
Abstract :
PubMedSearch : Hess_2003_Biochemistry_42_6106
PubMedID: 12755612

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues - Carroll_2002_J.Med.Chem_45_4755
Author(s) : Carroll FI , Lee JR , Navarro HA , Ma W , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 45 :4755 , 2002
Abstract :
PubMedSearch : Carroll_2002_J.Med.Chem_45_4755
PubMedID: 12361403

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist - Carroll_2001_J.Med.Chem_44_4039
Author(s) : Carroll FI , Lee JR , Navarro HA , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 44 :4039 , 2001
Abstract :
PubMedSearch : Carroll_2001_J.Med.Chem_44_4039
PubMedID: 11708907

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues - Carroll_2001_J.Med.Chem_44_2229
Author(s) : Carroll FI , Liang F , Navarro HA , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 44 :2229 , 2001
Abstract :
PubMedSearch : Carroll_2001_J.Med.Chem_44_2229
PubMedID: 11405659

Title : Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs - Damaj_1999_J.Pharmacol.Exp.Ther_289_1229
Author(s) : Damaj MI , Slemmer JE , Carroll FI , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1229 , 1999
Abstract :
PubMedSearch : Damaj_1999_J.Pharmacol.Exp.Ther_289_1229
PubMedID: 10336510

Title : 6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent - Carroll_1987_J.Med.Chem_30_805
Author(s) : Carroll FI , Abraham P , Parham K , Griffith RC , Ahmad A , Richard MM , Padilla FN , Witkin JM , Chiang PK
Ref : Journal of Medicinal Chemistry , 30 :805 , 1987
Abstract :
PubMedSearch : Carroll_1987_J.Med.Chem_30_805
PubMedID: 3494849

Title : Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine - Miura_1986_Gen.Pharmacol_17_477
Author(s) : Miura GA , Chiang PK , Gordon RK , Doctor BP , Twine CE , Philip A , Kepler JA , Carroll FI
Ref : General Pharmacology , 17 :477 , 1986
Abstract :
PubMedSearch : Miura_1986_Gen.Pharmacol_17_477
PubMedID: 2875921