| Title : Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 - Tang_2011_FEBS.Lett_585_3409 |
| Author(s) : Tang HK , Chen KC , Liou GG , Cheng SC , Chien CH , Tang HY , Huang LH , Chang HP , Chou CY , Chen X |
| Ref : FEBS Letters , 585 :3409 , 2011 |
| Abstract : |
| PubMedSearch : Tang_2011_FEBS.Lett_585_3409 |
| PubMedID: 22001206 |
| Gene_locus related to this paper: human-DPP4 , human-DPP9 |
| Title : Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein - Tsai_2010_J.Med.Chem_53_6572 |
| Author(s) : Tsai TY , Yeh TK , Chen X , Hsu T , Jao YC , Huang CH , Song JS , Huang YC , Chien CH , Chiu JH , Yen SC , Tang HK , Chao YS , Jiaang WT |
| Ref : Journal of Medicinal Chemistry , 53 :6572 , 2010 |
| Abstract : |
| PubMedSearch : Tsai_2010_J.Med.Chem_53_6572 |
| PubMedID: 20718420 |
| Title : (2S,4S)-1-[2-(1,1-dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-p yrrolidine-2-carbonitrile: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV - Yeh_2010_Bioorg.Med.Chem.Lett_20_3596 |
| Author(s) : Yeh TK , Tsai TY , Hsu T , Cheng JH , Chen X , Song JS , Shy HS , Chiou MC , Chien CH , Tseng YJ , Huang CY , Yeh KC , Huang YL , Huang CH , Huang YW , Wang MH , Tang HK , Chao YS , Chen CT , Jiaang WT |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :3596 , 2010 |
| Abstract : |
| PubMedSearch : Yeh_2010_Bioorg.Med.Chem.Lett_20_3596 |
| PubMedID: 20483603 |
| Title : Biochemical properties and expression profile of human prolyl dipeptidase DPP9 - Tang_2009_Arch.Biochem.Biophys_485_120 |
| Author(s) : Tang HK , Tang HY , Hsu SC , Chu YR , Chien CH , Shu CH , Chen X |
| Ref : Archives of Biochemistry & Biophysics , 485 :120 , 2009 |
| Abstract : |
| PubMedSearch : Tang_2009_Arch.Biochem.Biophys_485_120 |
| PubMedID: 19268648 |
| Gene_locus related to this paper: human-DPP9 |
| Title : Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors - Tsai_2009_Bioorg.Med.Chem_17_2388 |
| Author(s) : Tsai TY , Hsu T , Chen CT , Cheng JH , Yeh TK , Chen X , Huang CY , Chang CN , Yeh KC , Hsieh SH , Chien CH , Chang YW , Huang CH , Huang YW , Huang CL , Wu SH , Wang MH , Lu CT , Chao YS , Jiaang WT |
| Ref : Bioorganic & Medicinal Chemistry , 17 :2388 , 2009 |
| Abstract : |
| PubMedSearch : Tsai_2009_Bioorg.Med.Chem_17_2388 |
| PubMedID: 19261480 |
| Title : Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8\/9 inhibitor - Wu_2009_Biochem.Pharmacol_78_203 |
| Author(s) : Wu JJ , Tang HK , Yeh TK , Chen CM , Shy HS , Chu YR , Chien CH , Tsai TY , Huang YC , Huang YL , Huang CH , Tseng HY , Jiaang WT , Chao YS , Chen X |
| Ref : Biochemical Pharmacology , 78 :203 , 2009 |
| Abstract : |
| PubMedSearch : Wu_2009_Biochem.Pharmacol_78_203 |
| PubMedID: 19439267 |
| Title : A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors - Lu_2008_Eur.J.Med.Chem_43_1603 |
| Author(s) : Lu IL , Tsai KC , Chiang YK , Jiaang WT , Wu SH , Mahindroo N , Chien CH , Lee SJ , Chen X , Chao YS , Wu SY |
| Ref : Eur Journal of Medicinal Chemistry , 43 :1603 , 2008 |
| Abstract : |
| PubMedSearch : Lu_2008_Eur.J.Med.Chem_43_1603 |
| PubMedID: 18207285 |
| Title : 3-[2-((2S)-2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes - Coumar_2007_Bioorg.Med.Chem.Lett_17_1274 |
| Author(s) : Coumar MS , Chang CN , Chen CT , Chen X , Chien CH , Tsai TY , Cheng JH , Wu HY , Han CH , Wu SH , Huang YW , Hsu T , Hsu LJ , Chao YS , Hsieh HP , Jiaang WT |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :1274 , 2007 |
| Abstract : |
| PubMedSearch : Coumar_2007_Bioorg.Med.Chem.Lett_17_1274 |
| PubMedID: 17194587 |
| Title : Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8 - Lee_2006_J.Biol.Chem_281_38653 |
| Author(s) : Lee HJ , Chen YS , Chou CY , Chien CH , Lin CH , Chang GG , Chen X |
| Ref : Journal of Biological Chemistry , 281 :38653 , 2006 |
| Abstract : |
| PubMedSearch : Lee_2006_J.Biol.Chem_281_38653 |
| PubMedID: 17040910 |
| Gene_locus related to this paper: human-DPP8 |
| Title : Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors - Tsai_2006_Bioorg.Med.Chem.Lett_16_3268 |
| Author(s) : Tsai TY , Coumar MS , Hsu T , Hsieh HP , Chien CH , Chen CT , Chang CN , Lo YK , Wu SH , Huang CY , Huang YW , Wang MH , Wu HY , Lee HJ , Chen X , Chao YS , Jiaang WT |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :3268 , 2006 |
| Abstract : |
| PubMedSearch : Tsai_2006_Bioorg.Med.Chem.Lett_16_3268 |
| PubMedID: 16581245 |
| Title : 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV - Tsu_2006_J.Med.Chem_49_373 |
| Author(s) : Tsu H , Chen X , Chen CT , Lee SJ , Chang CN , Kao KH , Coumar MS , Yeh YT , Chien CH , Wang HS , Lin KT , Chang YY , Wu SH , Chen YS , Lu IL , Wu SY , Tsai TY , Chen WC , Hsieh HP , Chao YS , Jiaang WT |
| Ref : Journal of Medicinal Chemistry , 49 :373 , 2006 |
| Abstract : |
| PubMedSearch : Tsu_2006_J.Med.Chem_49_373 |
| PubMedID: 16392822 |
| Title : Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8 - Jiaang_2005_Bioorg.Med.Chem.Lett_15_687 |
| Author(s) : Jiaang WT , Chen YS , Hsu T , Wu SH , Chien CH , Chang CN , Chang SP , Lee SJ , Chen X |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :687 , 2005 |
| Abstract : |
| PubMedSearch : Jiaang_2005_Bioorg.Med.Chem.Lett_15_687 |
| PubMedID: 15664838 |
| Gene_locus related to this paper: human-DPP8 |
| Title : Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors - Lu_2005_Bioorg.Med.Chem.Lett_15_3271 |
| Author(s) : Lu IL , Lee SJ , Tsu H , Wu SY , Kao KH , Chien CH , Chang YY , Chen YS , Cheng JH , Chang CN , Chen TW , Chang SP , Chen X , Jiaang WT |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3271 , 2005 |
| Abstract : |
| PubMedSearch : Lu_2005_Bioorg.Med.Chem.Lett_15_3271 |
| PubMedID: 15927466 |
| Title : Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells - Chen_2004_Protein.Expr.Purif_35_142 |
| Author(s) : Chen YS , Chien CH , Goparaju CM , Hsu JT , Liang PH , Chen X |
| Ref : Protein Expr Purif , 35 :142 , 2004 |
| Abstract : |
| PubMedSearch : Chen_2004_Protein.Expr.Purif_35_142 |
| PubMedID: 15039077 |
| Gene_locus related to this paper: human-DPP8 |