Francis PT

General

Full name : Francis Paul T

First name : Paul T

Mail : King's College London, Wolfson Centre for Age-Related Diseases, St Thomas Street, London, SE1 1UL

Zip Code :

City :

Country : United Kingdom

Email : paul.francis@kcl.ac.uk

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Fax :

Website :

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Comment

References (19)

Title : Serotonin 5-HT6 Receptor Antagonists in Alzheimer's Disease: Therapeutic Rationale and Current Development Status - Ferrero_2017_CNS.Drugs_31_19
Author(s) : Ferrero H , Solas M , Francis PT , Ramirez MJ
Ref : CNS Drugs , 31 :19 , 2017
Abstract :
PubMedSearch : Ferrero_2017_CNS.Drugs_31_19
PubMedID: 27914038

Title : Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status - Ramirez_2014_Drugs_74_729
Author(s) : Ramirez MJ , Lai MK , Tordera RM , Francis PT
Ref : Drugs , 74 :729 , 2014
Abstract :
PubMedSearch : Ramirez_2014_Drugs_74_729
PubMedID: 24802806

Title : Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer's disease - Francis_2012_Expert.Rev.Neurother_12_1351
Author(s) : Francis PT , Parsons CG , Jones RW
Ref : Expert Rev Neurother , 12 :1351 , 2012
Abstract :
PubMedSearch : Francis_2012_Expert.Rev.Neurother_12_1351
PubMedID: 23234396

Title : Cholinergic imbalance in the multiple sclerosis hippocampus - Kooi_2011_Acta.Neuropathol_122_313
Author(s) : Kooi EJ , Prins M , Bajic N , Belien JA , Gerritsen WH , van Horssen J , Aronica E , van Dam AM , Hoozemans JJ , Francis PT , van der Valk P , Geurts JJ
Ref : Acta Neuropathologica , 122 :313 , 2011
Abstract :
PubMedSearch : Kooi_2011_Acta.Neuropathol_122_313
PubMedID: 21691765

Title : Neurochemical basis for symptomatic treatment of Alzheimer's disease - Francis_2010_Neuropharmacol_59_221
Author(s) : Francis PT , Ramirez MJ , Lai MK
Ref : Neuropharmacology , 59 :221 , 2010
Abstract :
PubMedSearch : Francis_2010_Neuropharmacol_59_221
PubMedID: 20156462

Title : Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease - Lai_2006_Neurobiol.Dis_22_555
Author(s) : Lai MK , Tsang SW , Garcia-Alloza M , Minger SL , Nicoll JA , Esiri MM , Wong PT , Chen CP , Ramirez MJ , Francis PT
Ref : Neurobiol Dis , 22 :555 , 2006
Abstract :
PubMedSearch : Lai_2006_Neurobiol.Dis_22_555
PubMedID: 16473016

Title : A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease? - Francis_2005_Trends.Pharmacol.Sci_26_104
Author(s) : Francis PT , Nordberg A , Arnold SE
Ref : Trends in Pharmacological Sciences , 26 :104 , 2005
Abstract :
PubMedSearch : Francis_2005_Trends.Pharmacol.Sci_26_104
PubMedID: 15681028

Title : Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease - Garcia-Alloza_2005_Neuropsychologia_43_442
Author(s) : Garcia-Alloza M , Gil-Bea FJ , Diez-Ariza M , Chen CP , Francis PT , Lasheras B , Ramirez MJ
Ref : Neuropsychologia , 43 :442 , 2005
Abstract :
PubMedSearch : Garcia-Alloza_2005_Neuropsychologia_43_442
PubMedID: 15707619

Title : The interplay of neurotransmitters in Alzheimer's disease - Francis_2005_CNS.Spectr_10_6
Author(s) : Francis PT
Ref : CNS Spectr , 10 :6 , 2005
Abstract :
PubMedSearch : Francis_2005_CNS.Spectr_10_6
PubMedID: 16273023

Title : Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy - Wilkinson_2004_Drugs.Aging_21_453
Author(s) : Wilkinson DG , Francis PT , Schwam E , Payne-Parrish J
Ref : Drugs & Aging , 21 :453 , 2004
Abstract :
PubMedSearch : Wilkinson_2004_Drugs.Aging_21_453
PubMedID: 15132713

Title : The cholinergic system and cognitive and noncognitive behavioral dysfunction in Alzheimer?s disease. -
Author(s) : Francis PT , Minger SL
Ref : Cholinergic Mechanisms, CRC Press :431 , 2004
PubMedID:

Title : The cholinergic hypothesis of Alzheimer's disease: a review of progress - Francis_1999_J.Neurol.Neurosurg.Psychiatry_66_137
Author(s) : Francis PT , Palmer AM , Snape M , Wilcock GK
Ref : Journal of Neurology Neurosurg Psychiatry , 66 :137 , 1999
Abstract :
PubMedSearch : Francis_1999_J.Neurol.Neurosurg.Psychiatry_66_137
PubMedID: 10071091

Title : Changes in cortical nicotinic acetylcholine receptor numbers following unilateral destruction of pyramidal neurones by intrastriatal volkensin injection - Chessell_1995_Neurodegeneration_4_415
Author(s) : Chessell IP , Francis PT , Bowen DM
Ref : Neurodegeneration , 4 :415 , 1995
Abstract :
PubMedSearch : Chessell_1995_Neurodegeneration_4_415
PubMedID: 8846235

Title : Cholinomimetics increase glutamate outflow via an action on the corticostriatal pathway: implications for Alzheimer's disease - Dijk_1995_J.Neurochem_65_2165
Author(s) : Dijk SN , Francis PT , Stratmann GC , Bowen DM
Ref : Journal of Neurochemistry , 65 :2165 , 1995
Abstract :
PubMedSearch : Dijk_1995_J.Neurochem_65_2165
PubMedID: 7595503

Title : Antemortem measurements of neurotransmission: possible implications for pharmacotherapy of Alzheimer's disease and depression - Francis_1993_J.Neurol.Neurosurg.Psychiatry_56_80
Author(s) : Francis PT , Pangalos MN , Stephens PH , Bartlett JR , Bridges PK , Malizia AL , Neary D , Procter AW , Thomas DJ , Bowen DM
Ref : Journal of Neurology Neurosurg Psychiatry , 56 :80 , 1993
Abstract :
PubMedSearch : Francis_1993_J.Neurol.Neurosurg.Psychiatry_56_80
PubMedID: 7679142

Title : Neurotransmitters and second messengers in aging and Alzheimer's disease - Francis_1993_Ann.N.Y.Acad.Sci_695_19
Author(s) : Francis PT , Webster MT , Chessell IP , Holmes C , Stratmann GC , Procter AW , Cross AJ , Green AR , Bowen DM
Ref : Annals of the New York Academy of Sciences , 695 :19 , 1993
Abstract :
PubMedSearch : Francis_1993_Ann.N.Y.Acad.Sci_695_19
PubMedID: 7902054

Title : Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats - Francis_1990_Epilepsia_31_697
Author(s) : Francis PT , Lowe SL , Bowen DM , Jefferys JG
Ref : Epilepsia , 31 :697 , 1990
Abstract :
PubMedSearch : Francis_1990_Epilepsia_31_697
PubMedID: 1700950

Title : Tacrine, a drug with therapeutic potential for dementia: post-mortem biochemical evidence - Francis_1989_Can.J.Neurol.Sci_16_504
Author(s) : Francis PT , Bowen DM
Ref : Can Journal of Neurology Sci , 16 :504 , 1989
Abstract :
PubMedSearch : Francis_1989_Can.J.Neurol.Sci_16_504
PubMedID: 2572313

Title : Neurochemical studies of early-onset Alzheimer's disease. Possible influence on treatment - Francis_1985_N.Engl.J.Med_313_7
Author(s) : Francis PT , Palmer AM , Sims NR , Bowen DM , Davison AN , Esiri MM , Neary D , Snowden JS , Wilcock GK
Ref : N Engl J Med , 313 :7 , 1985
Abstract :
PubMedSearch : Francis_1985_N.Engl.J.Med_313_7
PubMedID: 2582256