Haga T

General

Full name : Haga Tatsuya

First name : Tatsuya

Mail : Department of Biochemistry, Hamamatsu University School of Medicine, Hamatsu

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Country : Japan

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References (39)

Title : Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist - Haga_2012_Nature_482_547
Author(s) : Haga K , Kruse AC , Asada H , Yurugi-Kobayashi T , Shiroishi M , Zhang C , Weis WI , Okada T , Kobilka BK , Haga T , Kobayashi T
Ref : Nature , 482 :547 , 2012
Abstract :
PubMedSearch : Haga_2012_Nature_482_547
PubMedID: 22278061

Title : Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase - Fujii_2009_J.Neurosci.Res_87_3024
Author(s) : Fujii T , Masai M , Misawa H , Okuda T , Takada-Takatori Y , Moriwaki Y , Haga T , Kawashima K
Ref : Journal of Neuroscience Research , 87 :3024 , 2009
Abstract :
PubMedSearch : Fujii_2009_J.Neurosci.Res_87_3024
PubMedID: 19405101

Title : Detection of the high-affinity choline transporter in the MOLT-3 human leukemic T-cell line - Fujii_2003_Life.Sci_72_2131
Author(s) : Fujii T , Okuda T , Haga T , Kawashima K
Ref : Life Sciences , 72 :2131 , 2003
Abstract :
PubMedSearch : Fujii_2003_Life.Sci_72_2131
PubMedID: 12628469

Title : Role of receptor kinase in long-term desensitization of the cardiac muscarinic receptor-K+ channel system - Shui_2002_Am.J.Physiol.Heart.Circ.Physiol_283_H819
Author(s) : Shui Z , Khan IA , Tsuga H , Dobrzynski H , Haga T , Henderson Z , Boyett MR
Ref : American Journal of Physiology Heart Circ Physiol , 283 :H819 , 2002
Abstract :
PubMedSearch : Shui_2002_Am.J.Physiol.Heart.Circ.Physiol_283_H819
PubMedID: 12124232

Title : Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate - Okuda_2002_J.Biol.Chem_277_45315
Author(s) : Okuda T , Okamura M , Kaitsuka C , Haga T , Gurwitz D
Ref : Journal of Biological Chemistry , 277 :45315 , 2002
Abstract :
PubMedSearch : Okuda_2002_J.Biol.Chem_277_45315
PubMedID: 12237312

Title : Effects of toluene exposure on signal transduction: toluene reduced the signaling via stimulation of human muscarinic acetylcholine receptor m2 subtypes in CHO cells - Tsuga_2002_Jpn.J.Pharmacol_89_282
Author(s) : Tsuga H , Haga T , Honma T
Ref : Japanese Journal of Pharmacology , 89 :282 , 2002
Abstract :
PubMedSearch : Tsuga_2002_Jpn.J.Pharmacol_89_282
PubMedID: 12184734

Title : Poster: Conformation of (S)-methacholine bound to the M2 muscarinic acetylcholine receptor -
Author(s) : Furukawa H , Haga T , Muto Y , Yokoyama S , Hamada T , Hirota H
Ref : Life Sciences , 68 :2621 , 2001
PubMedID:

Title : Alterations of muscarinic acetylcholine receptor subtypes in diffuse lewy body disease: relation to Alzheimer's disease - Shiozaki_1999_J.Neurol.Neurosurg.Psychiatry_67_209
Author(s) : Shiozaki K , Iseki E , Uchiyama H , Watanabe Y , Haga T , Kameyama K , Ikeda T , Yamamoto T , Kosaka K
Ref : Journal of Neurology Neurosurg Psychiatry , 67 :209 , 1999
Abstract :
PubMedSearch : Shiozaki_1999_J.Neurol.Neurosurg.Psychiatry_67_209
PubMedID: 10406992

Title : Control elements of muscarinic receptor gene expression - Saffen_1999_Life.Sci_64(6-7)_479
Author(s) : Saffen D , Mieda M , Okamura M , Haga T
Ref : Life Sciences , 64 :479 , 1999
Abstract :
PubMedSearch : Saffen_1999_Life.Sci_64(6-7)_479
PubMedID: 10069513

Title : Desensitization of human muscarinic acetylcholine receptor m2 subtypes is caused by their sequestration\/internalization - Tsuga_1998_J.Biochem_124_863
Author(s) : Tsuga H , Kameyama K , Haga T
Ref : J Biochem , 124 :863 , 1998
Abstract :
PubMedSearch : Tsuga_1998_J.Biochem_124_863
PubMedID: 9756635

Title : Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein-coupled receptor kinase 2 - Tsuga_1998_J.Biol.Chem_273_5323
Author(s) : Tsuga H , Kameyama K , Haga T , Honma T , Lameh J , Sadee W
Ref : Journal of Biological Chemistry , 273 :5323 , 1998
Abstract :
PubMedSearch : Tsuga_1998_J.Biol.Chem_273_5323
PubMedID: 9478991

Title : Sequestration of human muscarinic acetylcholine receptor hm1-hm5 subtypes: effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6 - Tsuga_1998_J.Pharmacol.Exp.Ther_284_1218
Author(s) : Tsuga H , Okuno E , Kameyama K , Haga T
Ref : Journal of Pharmacology & Experimental Therapeutics , 284 :1218 , 1998
Abstract :
PubMedSearch : Tsuga_1998_J.Pharmacol.Exp.Ther_284_1218
PubMedID: 9495886

Title : Role of receptor kinase in short-term desensitization of cardiac muscarinic K+ channels expressed in Chinese hamster ovary cells - Shui_1998_J.Physiol_507 ( Pt 2)_325
Author(s) : Shui Z , Khan IA , Tsuga H , Haga T , Boyett MR
Ref : Journal of Physiology , 507 ( Pt 2) :325 , 1998
Abstract :
PubMedSearch : Shui_1998_J.Physiol_507 ( Pt 2)_325
PubMedID: 9518696

Title : Poster: Inhibition by calmodulin or S100 protein of agonist-dependent phosphorylation of m2 muscarinic receptors by G protein-coupled receptor kinase 2 -
Author(s) : Haga K , Haga T
Ref : Life Sciences , 60 :1184 , 1997
PubMedID:

Title : Poster: Effects of G protein-coupled receptor kinases on desensitization of muscarinic receptors -
Author(s) : Tsuga H , Honma T , Okuno E , Kameyama K , Haga T
Ref : Life Sciences , 60 :1184 , 1997
PubMedID:

Title : [Acetylcholine receptor] -
Author(s) : Ebihara T , Haga T
Ref : Tanpakushitsu Kakusan Koso , 42 :275 , 1997
PubMedID: 9162961

Title : Ca2+-dependent inhibition of G protein-coupled receptor kinase 2 by calmodulin - Haga_1997_Biochemistry_36_1315
Author(s) : Haga K , Tsuga H , Haga T
Ref : Biochemistry , 36 :1315 , 1997
Abstract :
PubMedSearch : Haga_1997_Biochemistry_36_1315
PubMedID: 9063879

Title : Expression of the rat m4 muscarinic acetylcholine receptor gene is regulated by the neuron-restrictive silencer element\/repressor element 1 - Mieda_1997_J.Biol.Chem_272_5854
Author(s) : Mieda M , Haga T , Saffen DW
Ref : Journal of Biological Chemistry , 272 :5854 , 1997
Abstract :
PubMedSearch : Mieda_1997_J.Biol.Chem_272_5854
PubMedID: 9038202

Title : Poster: Allosteric ligand-receptor-G protein interactions in lipid vesicles -
Author(s) : Jakubik J , Haga T , Tucek S
Ref : Life Sciences , 60 :1170 , 1997
PubMedID:

Title : Phosphorylation of human m1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 and protein kinase C - Haga_1996_J.Biol.Chem_271_2776
Author(s) : Haga K , Kameyama K , Haga T , Kikkawa U , Shiozaki K , Uchiyama H
Ref : Journal of Biological Chemistry , 271 :2776 , 1996
Abstract :
PubMedSearch : Haga_1996_J.Biol.Chem_271_2776
PubMedID: 8576254

Title : Promoter region of the rat m4 muscarinic acetylcholine receptor gene contains a cell type-specific silencer element - Mieda_1996_J.Biol.Chem_271_5177
Author(s) : Mieda M , Haga T , Saffen DW
Ref : Journal of Biological Chemistry , 271 :5177 , 1996
Abstract :
PubMedSearch : Mieda_1996_J.Biol.Chem_271_5177
PubMedID: 8617799

Title : G protein-coupled receptor kinase: phosphorylation of muscarinic receptors and facilitation of receptor sequestration -
Author(s) : Haga T , Haga K , Kameyama K , Tsuga H
Ref : Advances in Pharmacology , 36 :173 , 1996
PubMedID: 8783560

Title : Receptor kinase-dependent desensitization of the muscarinic K+ current in rat atrial cells - Shui_1995_J.Physiol_487 ( Pt 2)_359
Author(s) : Shui Z , Boyett MR , Zang WJ , Haga T , Kameyama K
Ref : Journal of Physiology , 487 ( Pt 2) :359 , 1995
Abstract :
PubMedSearch : Shui_1995_J.Physiol_487 ( Pt 2)_359
PubMedID: 8558469

Title : Characterization of Gq family G proteins GL1 alpha (G14 alpha), GL2 alpha (G11 alpha), and Gq alpha expressed in the baculovirus-insect cell system - Nakamura_1995_J.Biol.Chem_270_6246
Author(s) : Nakamura F , Kato M , Kameyama K , Nukada T , Haga T , Kato H , Takenawa T , Kikkawa U
Ref : Journal of Biological Chemistry , 270 :6246 , 1995
Abstract :
PubMedSearch : Nakamura_1995_J.Biol.Chem_270_6246
PubMedID: 7890762

Title : Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells - Dong_1995_J.Pharmacol.Exp.Ther_274_378
Author(s) : Dong GZ , Kameyama K , Rinken A , Haga T
Ref : Journal of Pharmacology & Experimental Therapeutics , 274 :378 , 1995
Abstract :
PubMedSearch : Dong_1995_J.Pharmacol.Exp.Ther_274_378
PubMedID: 7616422

Title : Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2 - Tsuga_1994_J.Biol.Chem_269_32522
Author(s) : Tsuga H , Kameyama K , Haga T , Kurose H , Nagao T
Ref : Journal of Biological Chemistry , 269 :32522 , 1994
Abstract :
PubMedSearch : Tsuga_1994_J.Biol.Chem_269_32522
PubMedID: 7798253

Title : Synergistic activation of a G protein-coupled receptor kinase by G protein beta gamma subunits and mastoparan or related peptides - Haga_1994_J.Biol.Chem_269_12594
Author(s) : Haga K , Kameyama K , Haga T
Ref : Journal of Biological Chemistry , 269 :12594 , 1994
Abstract :
PubMedSearch : Haga_1994_J.Biol.Chem_269_12594
PubMedID: 8175667

Title : [Regulation of G protein-coupled receptor kinase activity] - Haga_1994_Nihon.Yakurigaku.Zasshi_104_207
Author(s) : Haga T , Haga K , Kameyama K , Nakata H
Ref : Nihon Yakurigaku Zasshi , 104 :207 , 1994
Abstract :
PubMedSearch : Haga_1994_Nihon.Yakurigaku.Zasshi_104_207
PubMedID: 7959413

Title : Solubilization of muscarinic receptor subtypes from baculovirus infected Sf9 insect cells - Rinken_1994_Biochem.Pharmacol_48_1245
Author(s) : Rinken A , Kameyama K , Haga T , Engstrom L
Ref : Biochemical Pharmacology , 48 :1245 , 1994
Abstract :
PubMedSearch : Rinken_1994_Biochem.Pharmacol_48_1245
PubMedID: 7945418

Title : Location of agonist-dependent-phosphorylation sites in the third intracellular loop of muscarinic acetylcholine receptors (m2 subtype) - Nakata_1994_Eur.J.Biochem_220_29
Author(s) : Nakata H , Kameyama K , Haga K , Haga T
Ref : European Journal of Biochemistry , 220 :29 , 1994
Abstract :
PubMedSearch : Nakata_1994_Eur.J.Biochem_220_29
PubMedID: 8119296

Title : Activation of a GTP-binding protein and a GTP-binding-protein-coupled receptor kinase (beta-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites - Kameyama_1994_Eur.J.Biochem_226_267
Author(s) : Kameyama K , Haga K , Haga T , Moro O , Sadee W
Ref : European Journal of Biochemistry , 226 :267 , 1994
Abstract :
PubMedSearch : Kameyama_1994_Eur.J.Biochem_226_267
PubMedID: 8001544

Title : Phosphorylation of muscarinic receptors: regulation by G proteins - Haga_1993_Life.Sci_52(5-6)_421
Author(s) : Haga T , Haga K , Kameyama K , Nakata H
Ref : Life Sciences , 52 :421 , 1993
Abstract :
PubMedSearch : Haga_1993_Life.Sci_52(5-6)_421
PubMedID: 8441323

Title : Poster: Effects of Mg2+ on the interaction of atrial muscarinic receptors and G proteins -
Author(s) : Shiozaki K , Haga T
Ref : Life Sciences , 52(5-6) :567 , 1993
PubMedID:

Title : Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase - Kameyama_1993_J.Biol.Chem_268_7753
Author(s) : Kameyama K , Haga K , Haga T , Kontani K , Katada T , Fukada Y
Ref : Journal of Biological Chemistry , 268 :7753 , 1993
Abstract :
PubMedSearch : Kameyama_1993_J.Biol.Chem_268_7753
PubMedID: 8463305

Title : Carbachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland - Kajimura_1990_Eur.J.Pharmacol_178_59
Author(s) : Kajimura M , Haga T , Ichiyama A , Kaneko E , Honda N
Ref : European Journal of Pharmacology , 178 :59 , 1990
Abstract :
PubMedSearch : Kajimura_1990_Eur.J.Pharmacol_178_59
PubMedID: 2332028

Title : [Muscarinic acetylcholine receptor] -
Author(s) : Kameyama K , Haga T
Ref : Tanpakushitsu Kakusan Koso , 35 :677 , 1990
PubMedID: 1692143

Title : Molecular properties of muscarinic receptors -
Author(s) : Haga T , Haga K , Berstein G , Nishiyama T , Uchiyama H , Ichiyama A
Ref : Trends in Pharmacological Sciences , Suppl :12 , 1988
PubMedID: 3074530

Title : Hydrodynamic properties of muscarinic acetylcholine receptors solubilized from rat forebrain - Berrie_1984_Br.J.Pharmacol_82_839
Author(s) : Berrie CP , Birdsall NJ , Haga K , Haga T , Hulme EC
Ref : British Journal of Pharmacology , 82 :839 , 1984
Abstract :
PubMedSearch : Berrie_1984_Br.J.Pharmacol_82_839
PubMedID: 6478114

Title : Solubilisation and molecular characterisation of muscarinic acetylcholine receptors - Hulme_1983_J.Recept.Res_3_301
Author(s) : Hulme EC , Berrie CP , Haga T , Birdsall NJ , Burgen AS , Stockton J
Ref : J Recept Res , 3 :301 , 1983
Abstract :
PubMedSearch : Hulme_1983_J.Recept.Res_3_301
PubMedID: 6854547