Full name : Lameh Jelveh
First name : Jelveh
Mail : ACADIA Pharmaceuticals Inc., 3911 Sorrento Valley Blvd., San Diego, CA 92129
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Country : USA
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Comment
Title : Discovery of potential antipsychotic agents possessing pro-cognitive properties - Lameh_2012_Naunyn.Schmiedebergs.Arch.Pharmacol_385_313 |
Author(s) : Lameh J , McFarland K , Ohlsson J , Ek F , Piu F , Burstein ES , Tabatabaei A , Olsson R , Bradley SR , Bonhaus DW |
Ref : Naunyn Schmiedebergs Arch Pharmacol , 385 :313 , 2012 |
Abstract : |
PubMedSearch : Lameh_2012_Naunyn.Schmiedebergs.Arch.Pharmacol_385_313 |
PubMedID: 22083558 |
Title : AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model - Bradley_2010_Neuropharmacol_58_365 |
Author(s) : Bradley SR , Lameh J , Ohrmund L , Son T , Bajpai A , Nguyen D , Friberg M , Burstein ES , Spalding TA , Ott TR , Schiffer HH , Tabatabaei A , McFarland K , Davis RE , Bonhaus DW |
Ref : Neuropharmacology , 58 :365 , 2010 |
Abstract : |
PubMedSearch : Bradley_2010_Neuropharmacol_58_365 |
PubMedID: 19835892 |
Title : Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands - Davis_2009_BMC.Pharmacol_9_14 |
Author(s) : Davis CN , Bradley SR , Schiffer HH , Friberg M , Koch K , Tolf BR , Bonhaus DW , Lameh J |
Ref : BMC Pharmacol , 9 :14 , 2009 |
Abstract : |
PubMedSearch : Davis_2009_BMC.Pharmacol_9_14 |
PubMedID: 19951444 |
Title : Pharmacology of N-desmethylclozapine - Lameh_2007_Pharmacol.Ther_115_223 |
Author(s) : Lameh J , Burstein ES , Taylor E , Weiner DM , Vanover KE , Bonhaus DW |
Ref : Pharmacol Ther , 115 :223 , 2007 |
Abstract : |
PubMedSearch : Lameh_2007_Pharmacol.Ther_115_223 |
PubMedID: 17583355 |
Title : The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine - Weiner_2004_Psychopharmacology.(Berl)_177_207 |
Author(s) : Weiner DM , Meltzer HY , Veinbergs I , Donohue EM , Spalding TA , Smith TT , Mohell N , Harvey SC , Lameh J , Nash N , Vanover KE , Olsson R , Jayathilake K , Lee M , Levey AI , Hacksell U , Burstein ES , Davis RE , Brann MR |
Ref : Psychopharmacology (Berl) , 177 :207 , 2004 |
Abstract : |
PubMedSearch : Weiner_2004_Psychopharmacology.(Berl)_177_207 |
PubMedID: 15258717 |
Title : Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory - DeLorey_2001_Eur.J.Pharmacol_426_45 |
Author(s) : DeLorey TM , Lin RC , McBrady B , He X , Cook JM , Lameh J , Loew GH |
Ref : European Journal of Pharmacology , 426 :45 , 2001 |
Abstract : |
PubMedSearch : DeLorey_2001_Eur.J.Pharmacol_426_45 |
PubMedID: 11525770 |
Title : Differential regulation of muscarinic M1 and M3 receptors by a putative phosphorylation domain - Shockley_1999_Eur.J.Pharmacol_377_137 |
Author(s) : Shockley MS , Tolbert LM , Tobin AB , Nahorski SR , Sadee W , Lameh J |
Ref : European Journal of Pharmacology , 377 :137 , 1999 |
Abstract : |
PubMedSearch : Shockley_1999_Eur.J.Pharmacol_377_137 |
PubMedID: 10448936 |
Title : Poster: Multiphasic calcium currents stimulated by the HM1 receptors - |
Author(s) : Lin K , Quillan JM , Lameh J , Sadee W |
Ref : Life Sciences , 64 :577 , 1999 |
PubMedID: |
Title : Antibody to epitope tag induces internalization of human muscarinic subtype 1 receptor - Tolbert_1998_J.Neurochem_70_113 |
Author(s) : Tolbert LM , Lameh J |
Ref : Journal of Neurochemistry , 70 :113 , 1998 |
Abstract : |
PubMedSearch : Tolbert_1998_J.Neurochem_70_113 |
PubMedID: 9422353 |
Title : Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein-coupled receptor kinase 2 - Tsuga_1998_J.Biol.Chem_273_5323 |
Author(s) : Tsuga H , Kameyama K , Haga T , Honma T , Lameh J , Sadee W |
Ref : Journal of Biological Chemistry , 273 :5323 , 1998 |
Abstract : |
PubMedSearch : Tsuga_1998_J.Biol.Chem_273_5323 |
PubMedID: 9478991 |
Title : Residues specifically involved in down-regulation but not internalization of the m1 muscarinic acetylcholine receptor - Shockley_1997_J.Neurochem_68_601 |
Author(s) : Shockley MS , Burford NT , Sadee W , Lameh J |
Ref : Journal of Neurochemistry , 68 :601 , 1997 |
Abstract : |
PubMedSearch : Shockley_1997_J.Neurochem_68_601 |
PubMedID: 9003046 |
Title : Poster: Muscarinic receptors colocalize with proteins in clathrin-coated vesicles - |
Author(s) : Tolbert LM , Lameh J |
Ref : Life Sciences , 60 :1196 , 1997 |
PubMedID: |
Title : Human muscarinic cholinergic receptor Hm1 internalizes via clathrin-coated vesicles - Tolbert_1996_J.Biol.Chem_271_17335 |
Author(s) : Tolbert LM , Lameh J |
Ref : Journal of Biological Chemistry , 271 :17335 , 1996 |
Abstract : |
PubMedSearch : Tolbert_1996_J.Biol.Chem_271_17335 |
PubMedID: 8663385 |
Title : Poster: Determination of the pathway of muscarinic receptor internalization - |
Author(s) : Tolbert LM , Lameh J |
Ref : Life Sciences , 56(11-12) :1025 , 1995 |
PubMedID: |
Title : Activating and inactivating mutations in N- and C-terminal i3 loop junctions of muscarinic acetylcholine Hm1 receptors - Hogger_1995_J.Biol.Chem_270_7405 |
Author(s) : Hogger P , Shockley MS , Lameh J , Sadee W |
Ref : Journal of Biological Chemistry , 270 :7405 , 1995 |
Abstract : |
PubMedSearch : Hogger_1995_J.Biol.Chem_270_7405 |
PubMedID: 7706286 |
Title : Poster: Identification of residues in the intracellular loops of the human muscarinic cholinergic HM1 receptor involved in G-protein coupling and down-regulation - |
Author(s) : Shockley MS , Hogger P , Lameh J , Sadee W |
Ref : Life Sciences , 56(11-12) :1030 , 1995 |
PubMedID: |
Title : Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration - Moro_1994_J.Biol.Chem_269_6651 |
Author(s) : Moro O , Shockley MS , Lameh J , Sadee W |
Ref : Journal of Biological Chemistry , 269 :6651 , 1994 |
Abstract : |
PubMedSearch : Moro_1994_J.Biol.Chem_269_6651 |
PubMedID: 8120019 |
Title : Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling - Moro_1993_J.Biol.Chem_268_22273 |
Author(s) : Moro O , Lameh J , Hogger P , Sadee W |
Ref : Journal of Biological Chemistry , 268 :22273 , 1993 |
Abstract : |
PubMedSearch : Moro_1993_J.Biol.Chem_268_22273 |
PubMedID: 8226735 |
Title : Serine- and threonine-rich domain regulates internalization of muscarinic cholinergic receptors - Moro_1993_J.Biol.Chem_268_6862 |
Author(s) : Moro O , Lameh J , Sadee W |
Ref : Journal of Biological Chemistry , 268 :6862 , 1993 |
Abstract : |
PubMedSearch : Moro_1993_J.Biol.Chem_268_6862 |
PubMedID: 8463213 |
Title : Mutational analysis of third cytoplasmic loop domains in G-protein coupling of the HM1 muscarinic receptor - Arden_1992_Biochem.Biophys.Res.Commun_188_1111 |
Author(s) : Arden JR , Nagata O , Shockley MS , Philip M , Lameh J , Sadee W |
Ref : Biochemical & Biophysical Research Communications , 188 :1111 , 1992 |
Abstract : |
PubMedSearch : Arden_1992_Biochem.Biophys.Res.Commun_188_1111 |
PubMedID: 1445347 |
Title : Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop - Lameh_1992_J.Biol.Chem_267_13406 |
Author(s) : Lameh J , Philip M , Sharma YK , Moro O , Ramachandran J , Sadee W |
Ref : Journal of Biological Chemistry , 267 :13406 , 1992 |
Abstract : |
PubMedSearch : Lameh_1992_J.Biol.Chem_267_13406 |
PubMedID: 1618842 |
Title : Mapping the ligand binding pocket of the human muscarinic cholinergic receptor Hm1: contribution of tyrosine-82 - Drubbisch_1992_Pharm.Res_9_1644 |
Author(s) : Drubbisch V , Lameh J , Philip M , Sharma YK , Sadee W |
Ref : Pharm Res , 9 :1644 , 1992 |
Abstract : |
PubMedSearch : Drubbisch_1992_Pharm.Res_9_1644 |
PubMedID: 1488411 |
Title : Structure and function of G protein coupled receptors - Lameh_1990_Pharm.Res_7_1213 |
Author(s) : Lameh J , Cone RI , Maeda S , Philip M , Corbani M , Nadasdi L , Ramachandran J , Smith GM , Sadee W |
Ref : Pharm Res , 7 :1213 , 1990 |
Abstract : |
PubMedSearch : Lameh_1990_Pharm.Res_7_1213 |
PubMedID: 1965663 |
Title : Internalization of the Hm1 muscarinic cholinergic receptor involves the third cytoplasmic loop - Maeda_1990_FEBS.Lett_269_386 |
Author(s) : Maeda S , Lameh J , Mallet WG , Philip M , Ramachandran J , Sadee W |
Ref : FEBS Letters , 269 :386 , 1990 |
Abstract : |
PubMedSearch : Maeda_1990_FEBS.Lett_269_386 |
PubMedID: 2401364 |