| Title : Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359 - Hermes_2021_Nat.Commun_12_144 |
| Author(s) : Hermes C , Richarz R , Wirtz DA , Patt J , Hanke W , Kehraus S , Voss JH , Kuppers J , Ohbayashi T , Namasivayam V , Alenfelder J , Inoue A , Mergaert P , Gutschow M , Muller CE , Kostenis E , Konig GM , Crusemann M |
| Ref : Nat Commun , 12 :144 , 2021 |
| Abstract : |
| PubMedSearch : Hermes_2021_Nat.Commun_12_144 |
| PubMedID: 33420046 |
| Title : Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359 - Hermes_2021_Nat.Commun_12_144 |
| Author(s) : Hermes C , Richarz R , Wirtz DA , Patt J , Hanke W , Kehraus S , Voss JH , Kuppers J , Ohbayashi T , Namasivayam V , Alenfelder J , Inoue A , Mergaert P , Gutschow M , Muller CE , Kostenis E , Konig GM , Crusemann M |
| Ref : Nat Commun , 12 :144 , 2021 |
| Abstract : |
| PubMedSearch : Hermes_2021_Nat.Commun_12_144 |
| PubMedID: 33420046 |
| Title : Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359 - Hermes_2021_Nat.Commun_12_144 |
| Author(s) : Hermes C , Richarz R , Wirtz DA , Patt J , Hanke W , Kehraus S , Voss JH , Kuppers J , Ohbayashi T , Namasivayam V , Alenfelder J , Inoue A , Mergaert P , Gutschow M , Muller CE , Kostenis E , Konig GM , Crusemann M |
| Ref : Nat Commun , 12 :144 , 2021 |
| Abstract : |
| PubMedSearch : Hermes_2021_Nat.Commun_12_144 |
| PubMedID: 33420046 |
| Title : Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation - Kawanai_2016_Neurochem.Res_41_2574 |
| Author(s) : Kawanai T , Ago Y , Watanabe R , Inoue A , Taruta A , Onaka Y , Hasebe S , Hashimoto H , Matsuda T , Takuma K |
| Ref : Neurochem Res , 41 :2574 , 2016 |
| Abstract : |
| PubMedSearch : Kawanai_2016_Neurochem.Res_41_2574 |
| PubMedID: 27300699 |
| Title : Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation - Kawanai_2016_Neurochem.Res_41_2574 |
| Author(s) : Kawanai T , Ago Y , Watanabe R , Inoue A , Taruta A , Onaka Y , Hasebe S , Hashimoto H , Matsuda T , Takuma K |
| Ref : Neurochem Res , 41 :2574 , 2016 |
| Abstract : |
| PubMedSearch : Kawanai_2016_Neurochem.Res_41_2574 |
| PubMedID: 27300699 |
| Title : Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation - Kawanai_2016_Neurochem.Res_41_2574 |
| Author(s) : Kawanai T , Ago Y , Watanabe R , Inoue A , Taruta A , Onaka Y , Hasebe S , Hashimoto H , Matsuda T , Takuma K |
| Ref : Neurochem Res , 41 :2574 , 2016 |
| Abstract : |
| PubMedSearch : Kawanai_2016_Neurochem.Res_41_2574 |
| PubMedID: 27300699 |
| Title : Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair\/hypotrichosis: Establishment of a useful assay system for LPA6 - Hayashi_2015_J.Dermatol.Sci_78_197 |
| Author(s) : Hayashi R , Inoue A , Suga Y , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 78 :197 , 2015 |
| Abstract : |
| PubMedSearch : Hayashi_2015_J.Dermatol.Sci_78_197 |
| PubMedID: 25828854 |
| Title : Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair\/hypotrichosis: Establishment of a useful assay system for LPA6 - Hayashi_2015_J.Dermatol.Sci_78_197 |
| Author(s) : Hayashi R , Inoue A , Suga Y , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 78 :197 , 2015 |
| Abstract : |
| PubMedSearch : Hayashi_2015_J.Dermatol.Sci_78_197 |
| PubMedID: 25828854 |
| Title : Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair\/hypotrichosis: Establishment of a useful assay system for LPA6 - Hayashi_2015_J.Dermatol.Sci_78_197 |
| Author(s) : Hayashi R , Inoue A , Suga Y , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 78 :197 , 2015 |
| Abstract : |
| PubMedSearch : Hayashi_2015_J.Dermatol.Sci_78_197 |
| PubMedID: 25828854 |
| Title : A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1alpha in autosomal recessive wooly hair\/hypotrichosis - |
| Author(s) : Yoshizawa M , Nakamura M , Farooq M , Inoue A , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 72 :61 , 2013 |
| PubMedID: 23768866 |
| Gene_locus related to this paper: human-LIPH |
| Title : A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1alpha in autosomal recessive wooly hair\/hypotrichosis - |
| Author(s) : Yoshizawa M , Nakamura M , Farooq M , Inoue A , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 72 :61 , 2013 |
| PubMedID: 23768866 |
| Gene_locus related to this paper: human-LIPH |
| Title : A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1alpha in autosomal recessive wooly hair\/hypotrichosis - |
| Author(s) : Yoshizawa M , Nakamura M , Farooq M , Inoue A , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 72 :61 , 2013 |
| PubMedID: 23768866 |
| Gene_locus related to this paper: human-LIPH |
| Title : Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids - Arima_2012_J.Lipid.Res_53_513 |
| Author(s) : Arima N , Inoue A , Makide K , Nonaka T , Aoki J |
| Ref : J Lipid Res , 53 :513 , 2012 |
| Abstract : |
| PubMedSearch : Arima_2012_J.Lipid.Res_53_513 |
| PubMedID: 22172514 |
| Title : Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids - Arima_2012_J.Lipid.Res_53_513 |
| Author(s) : Arima N , Inoue A , Makide K , Nonaka T , Aoki J |
| Ref : J Lipid Res , 53 :513 , 2012 |
| Abstract : |
| PubMedSearch : Arima_2012_J.Lipid.Res_53_513 |
| PubMedID: 22172514 |
| Title : The beta9 loop domain of PA-PLA1alpha has a crucial role in autosomal recessive woolly hair\/hypotrichosis - |
| Author(s) : Shinkuma S , Inoue A , Aoki J , Nishie W , Natsuga K , Ujiie H , Nomura T , Abe R , Akiyama M , Shimizu H |
| Ref : Journal of Investigative Dermatology , 132 :2093 , 2012 |
| PubMedID: 22475755 |
| Gene_locus related to this paper: human-LIPH |
| Title : The beta9 loop domain of PA-PLA1alpha has a crucial role in autosomal recessive woolly hair\/hypotrichosis - |
| Author(s) : Shinkuma S , Inoue A , Aoki J , Nishie W , Natsuga K , Ujiie H , Nomura T , Abe R , Akiyama M , Shimizu H |
| Ref : Journal of Investigative Dermatology , 132 :2093 , 2012 |
| PubMedID: 22475755 |
| Gene_locus related to this paper: human-LIPH |
| Title : The beta9 loop domain of PA-PLA1alpha has a crucial role in autosomal recessive woolly hair\/hypotrichosis - |
| Author(s) : Shinkuma S , Inoue A , Aoki J , Nishie W , Natsuga K , Ujiie H , Nomura T , Abe R , Akiyama M , Shimizu H |
| Ref : Journal of Investigative Dermatology , 132 :2093 , 2012 |
| PubMedID: 22475755 |
| Gene_locus related to this paper: human-LIPH |
| Title : Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids - Arima_2012_J.Lipid.Res_53_513 |
| Author(s) : Arima N , Inoue A , Makide K , Nonaka T , Aoki J |
| Ref : J Lipid Res , 53 :513 , 2012 |
| Abstract : |
| PubMedSearch : Arima_2012_J.Lipid.Res_53_513 |
| PubMedID: 22172514 |
| Title : Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis - Shinkuma_2010_Hum.Mutat_31_602 |
| Author(s) : Shinkuma S , Akiyama M , Inoue A , Aoki J , Natsuga K , Nomura T , Arita K , Abe R , Ito K , Nakamura H , Ujiie H , Shibaki A , Suga H , Tsunemi Y , Nishie W , Shimizu H |
| Ref : Hum Mutat , 31 :602 , 2010 |
| Abstract : |
| PubMedSearch : Shinkuma_2010_Hum.Mutat_31_602 |
| PubMedID: 20213768 |
| Gene_locus related to this paper: human-LIPH |
| Title : Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis - Shinkuma_2010_Hum.Mutat_31_602 |
| Author(s) : Shinkuma S , Akiyama M , Inoue A , Aoki J , Natsuga K , Nomura T , Arita K , Abe R , Ito K , Nakamura H , Ujiie H , Shibaki A , Suga H , Tsunemi Y , Nishie W , Shimizu H |
| Ref : Hum Mutat , 31 :602 , 2010 |
| Abstract : |
| PubMedSearch : Shinkuma_2010_Hum.Mutat_31_602 |
| PubMedID: 20213768 |
| Gene_locus related to this paper: human-LIPH |
| Title : Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis - Shinkuma_2010_Hum.Mutat_31_602 |
| Author(s) : Shinkuma S , Akiyama M , Inoue A , Aoki J , Natsuga K , Nomura T , Arita K , Abe R , Ito K , Nakamura H , Ujiie H , Shibaki A , Suga H , Tsunemi Y , Nishie W , Shimizu H |
| Ref : Hum Mutat , 31 :602 , 2010 |
| Abstract : |
| PubMedSearch : Shinkuma_2010_Hum.Mutat_31_602 |
| PubMedID: 20213768 |
| Gene_locus related to this paper: human-LIPH |
| Title : Two pathways for lysophosphatidic acid production - Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| Author(s) : Aoki J , Inoue A , Okudaira S |
| Ref : Biochimica & Biophysica Acta , 1781 :513 , 2008 |
| Abstract : |
| PubMedSearch : Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| PubMedID: 18621144 |
| Gene_locus related to this paper: human-LIPH |
| Title : Two pathways for lysophosphatidic acid production - Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| Author(s) : Aoki J , Inoue A , Okudaira S |
| Ref : Biochimica & Biophysica Acta , 1781 :513 , 2008 |
| Abstract : |
| PubMedSearch : Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| PubMedID: 18621144 |
| Gene_locus related to this paper: human-LIPH |
| Title : Two pathways for lysophosphatidic acid production - Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| Author(s) : Aoki J , Inoue A , Okudaira S |
| Ref : Biochimica & Biophysica Acta , 1781 :513 , 2008 |
| Abstract : |
| PubMedSearch : Aoki_2008_Biochim.Biophys.Acta_1781_513 |
| PubMedID: 18621144 |
| Gene_locus related to this paper: human-LIPH |
| Title : Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family - Aoki_2007_Biochimie_89_197 |
| Author(s) : Aoki J , Inoue A , Makide K , Saiki N , Arai H |
| Ref : Biochimie , 89 :197 , 2007 |
| Abstract : |
| PubMedSearch : Aoki_2007_Biochimie_89_197 |
| PubMedID: 17101204 |
| Title : Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family - Aoki_2007_Biochimie_89_197 |
| Author(s) : Aoki J , Inoue A , Makide K , Saiki N , Arai H |
| Ref : Biochimie , 89 :197 , 2007 |
| Abstract : |
| PubMedSearch : Aoki_2007_Biochimie_89_197 |
| PubMedID: 17101204 |
| Title : Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family - Aoki_2007_Biochimie_89_197 |
| Author(s) : Aoki J , Inoue A , Makide K , Saiki N , Arai H |
| Ref : Biochimie , 89 :197 , 2007 |
| Abstract : |
| PubMedSearch : Aoki_2007_Biochimie_89_197 |
| PubMedID: 17101204 |
| Title : An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125 - Takami_1999_Extremophiles_3_21 |
| Author(s) : Takami H , Nakasone K , Hirama C , Takaki Y , Masui N , Fuji F , Nakamura Y , Inoue A |
| Ref : Extremophiles , 3 :21 , 1999 |
| Abstract : |
| PubMedSearch : Takami_1999_Extremophiles_3_21 |
| PubMedID: 10086841 |
| Title : An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125 - Takami_1999_Extremophiles_3_21 |
| Author(s) : Takami H , Nakasone K , Hirama C , Takaki Y , Masui N , Fuji F , Nakamura Y , Inoue A |
| Ref : Extremophiles , 3 :21 , 1999 |
| Abstract : |
| PubMedSearch : Takami_1999_Extremophiles_3_21 |
| PubMedID: 10086841 |
| Title : An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125 - Takami_1999_Extremophiles_3_21 |
| Author(s) : Takami H , Nakasone K , Hirama C , Takaki Y , Masui N , Fuji F , Nakamura Y , Inoue A |
| Ref : Extremophiles , 3 :21 , 1999 |
| Abstract : |
| PubMedSearch : Takami_1999_Extremophiles_3_21 |
| PubMedID: 10086841 |
| Title : Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates - Inoue_1997_Science_276_1428 |
| Author(s) : Inoue A , Sanes JR |
| Ref : Science , 276 :1428 , 1997 |
| Abstract : |
| PubMedSearch : Inoue_1997_Science_276_1428 |
| PubMedID: 9162013 |
| Title : Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates - Inoue_1997_Science_276_1428 |
| Author(s) : Inoue A , Sanes JR |
| Ref : Science , 276 :1428 , 1997 |
| Abstract : |
| PubMedSearch : Inoue_1997_Science_276_1428 |
| PubMedID: 9162013 |
| Title : Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates - Inoue_1997_Science_276_1428 |
| Author(s) : Inoue A , Sanes JR |
| Ref : Science , 276 :1428 , 1997 |
| Abstract : |
| PubMedSearch : Inoue_1997_Science_276_1428 |
| PubMedID: 9162013 |
| Title : The simulated binding of (+\/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]m eth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses - Inoue_1996_J.Med.Chem_39_4460 |
| Author(s) : Inoue A , Kawai T , Wakita M , Iimura Y , Sugimoto H , Kawakami Y |
| Ref : Journal of Medicinal Chemistry , 39 :4460 , 1996 |
| Abstract : |
| PubMedSearch : Inoue_1996_J.Med.Chem_39_4460 |
| PubMedID: 8893840 |
| Title : The simulated binding of (+\/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]m eth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses - Inoue_1996_J.Med.Chem_39_4460 |
| Author(s) : Inoue A , Kawai T , Wakita M , Iimura Y , Sugimoto H , Kawakami Y |
| Ref : Journal of Medicinal Chemistry , 39 :4460 , 1996 |
| Abstract : |
| PubMedSearch : Inoue_1996_J.Med.Chem_39_4460 |
| PubMedID: 8893840 |
| Title : The simulated binding of (+\/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]m eth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses - Inoue_1996_J.Med.Chem_39_4460 |
| Author(s) : Inoue A , Kawai T , Wakita M , Iimura Y , Sugimoto H , Kawakami Y |
| Ref : Journal of Medicinal Chemistry , 39 :4460 , 1996 |
| Abstract : |
| PubMedSearch : Inoue_1996_J.Med.Chem_39_4460 |
| PubMedID: 8893840 |
| Title : The rationale for E2020 as a potent acetylcholinesterase inhibitor - Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| Author(s) : Kawakami Y , Inoue A , Kawai T , Wakita M , Sugimoto H , Hopfinger AJ |
| Ref : Bioorganic & Medicinal Chemistry , 4 :1429 , 1996 |
| Abstract : |
| PubMedSearch : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| PubMedID: 8894101 |
| Title : The rationale for E2020 as a potent acetylcholinesterase inhibitor - Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| Author(s) : Kawakami Y , Inoue A , Kawai T , Wakita M , Sugimoto H , Hopfinger AJ |
| Ref : Bioorganic & Medicinal Chemistry , 4 :1429 , 1996 |
| Abstract : |
| PubMedSearch : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| PubMedID: 8894101 |
| Title : The rationale for E2020 as a potent acetylcholinesterase inhibitor - Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| Author(s) : Kawakami Y , Inoue A , Kawai T , Wakita M , Sugimoto H , Hopfinger AJ |
| Ref : Bioorganic & Medicinal Chemistry , 4 :1429 , 1996 |
| Abstract : |
| PubMedSearch : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| PubMedID: 8894101 |