Report for Sugimoto H

General

Full name : Sugimoto Hachiro

First name : Hachiro

Mail : Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501

Zip Code :

City :

Country : Japan

Email : hsugimot@pharm.kyoto-u.ac.jp

Phone :

Fax :

Website :

Directory :

References (34)

Title : The study of ghrelin deacylation enzymes - Satou_2012_Methods.Enzymol_514_165
Author(s) : Satou M , Sugimoto H
Ref : Methods Enzymol , 514 :165 , 2012
Abstract : Satou_2012_Methods.Enzymol_514_165
ESTHER : Satou_2012_Methods.Enzymol_514_165
PubMedSearch : Satou_2012_Methods.Enzymol_514_165
PubMedID: 22975053

Title : Understanding the functional significance of ghrelin processing and degradation - Satou_2011_Peptides_32_2183
Author(s) : Satou M , Nakamura Y , Ando H , Sugimoto H
Ref : Peptides , 32 :2183 , 2011
Abstract : Satou_2011_Peptides_32_2183
ESTHER : Satou_2011_Peptides_32_2183
PubMedSearch : Satou_2011_Peptides_32_2183
PubMedID: 21763742

Title : Mechanisms of chronic nicotine treatment-induced enhancement of the sensitivity of cortical neurons to the neuroprotective effect of donepezil in cortical neurons - Takada-Takatori_2010_J.Pharmacol.Sci_112_265
Author(s) : Takada-Takatori Y , Kume T , Izumi Y , Niidome T , Fujii T , Sugimoto H , Akaike A
Ref : J Pharmacol Sci , 112 :265 , 2010
Abstract : Takada-Takatori_2010_J.Pharmacol.Sci_112_265
ESTHER : Takada-Takatori_2010_J.Pharmacol.Sci_112_265
PubMedSearch : Takada-Takatori_2010_J.Pharmacol.Sci_112_265
PubMedID: 20173312

Title : Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718
Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Kunimoto R , Tsumura Y , Akaike A , Niidome T , Okuno Y , Takahashi T , Sugimoto H
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1718 , 2010
Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718
ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718
PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718
PubMedID: 20137934

Title : Cadmium reduces adipocyte size and expression levels of adiponectin and Peg1\/Mest in adipose tissue - Kawakami_2010_Toxicology_267_20
Author(s) : Kawakami T , Sugimoto H , Furuichi R , Kadota Y , Inoue M , Setsu K , Suzuki S , Sato M
Ref : Toxicology , 267 :20 , 2010
Abstract : Kawakami_2010_Toxicology_267_20
ESTHER : Kawakami_2010_Toxicology_267_20
PubMedSearch : Kawakami_2010_Toxicology_267_20
PubMedID: 19666079

Title : Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors - Shen_2010_Br.J.Pharmacol_161_127
Author(s) : Shen H , Kihara T , Hongo H , Wu X , Kem WR , Shimohama S , Akaike A , Niidome T , Sugimoto H
Ref : British Journal of Pharmacology , 161 :127 , 2010
Abstract : Shen_2010_Br.J.Pharmacol_161_127
ESTHER : Shen_2010_Br.J.Pharmacol_161_127
PubMedSearch : Shen_2010_Br.J.Pharmacol_161_127
PubMedID: 20718745

Title : [Development of anti-Alzheimer's disease drug based on beta-amyloid hypothesis] - Sugimoto_2010_Yakugaku.Zasshi_130_521
Author(s) : Sugimoto H
Ref : Yakugaku Zasshi , 130 :521 , 2010
Abstract : Sugimoto_2010_Yakugaku.Zasshi_130_521
ESTHER : Sugimoto_2010_Yakugaku.Zasshi_130_521
PubMedSearch : Sugimoto_2010_Yakugaku.Zasshi_130_521
PubMedID: 20371996

Title : Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721
Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Tsumura Y , Akaike A , Niidome T , Takahashi T , Sugimoto H
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1721 , 2010
Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721
ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721
PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721
PubMedID: 20137941

Title : Thioesterase activity and subcellular localization of acylprotein thioesterase 1\/lysophospholipase 1 - Hirano_2009_Biochim.Biophys.Acta_1791_797
Author(s) : Hirano T , Kishi M , Sugimoto H , Taguchi R , Obinata H , Ohshima N , Tatei K , Izumi T
Ref : Biochimica & Biophysica Acta , 1791 :797 , 2009
Abstract : Hirano_2009_Biochim.Biophys.Acta_1791_797
ESTHER : Hirano_2009_Biochim.Biophys.Acta_1791_797
PubMedSearch : Hirano_2009_Biochim.Biophys.Acta_1791_797
PubMedID: 19439193

Title : Roles of nicotinic receptors in acetylcholinesterase inhibitor-induced neuroprotection and nicotinic receptor up-regulation - Takada-Takatori_2009_Biol.Pharm.Bull_32_318
Author(s) : Takada-Takatori Y , Kume T , Izumi Y , Ohgi Y , Niidome T , Fujii T , Sugimoto H , Akaike A
Ref : Biol Pharm Bull , 32 :318 , 2009
Abstract : Takada-Takatori_2009_Biol.Pharm.Bull_32_318
ESTHER : Takada-Takatori_2009_Biol.Pharm.Bull_32_318
PubMedSearch : Takada-Takatori_2009_Biol.Pharm.Bull_32_318
PubMedID: 19252271

Title : Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment - Takada-Takatori_2008_Eur.J.Pharmacol_590_150
Author(s) : Takada-Takatori Y , Kume T , Ohgi Y , Fujii T , Niidome T , Sugimoto H , Akaike A
Ref : European Journal of Pharmacology , 590 :150 , 2008
Abstract : Takada-Takatori_2008_Eur.J.Pharmacol_590_150
ESTHER : Takada-Takatori_2008_Eur.J.Pharmacol_590_150
PubMedSearch : Takada-Takatori_2008_Eur.J.Pharmacol_590_150
PubMedID: 18585378

Title : Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil - Takada-Takatori_2008_J.Neurosci.Res_86_3575
Author(s) : Takada-Takatori Y , Kume T , Ohgi Y , Izumi Y , Niidome T , Fujii T , Sugimoto H , Akaike A
Ref : Journal of Neuroscience Research , 86 :3575 , 2008
Abstract : Takada-Takatori_2008_J.Neurosci.Res_86_3575
ESTHER : Takada-Takatori_2008_J.Neurosci.Res_86_3575
PubMedSearch : Takada-Takatori_2008_J.Neurosci.Res_86_3575
PubMedID: 18655200

Title : The new approach in development of anti-Alzheimer's disease drugs via the cholinergic hypothesis - Sugimoto_2008_Chem.Biol.Interact_175_204
Author(s) : Sugimoto H
Ref : Chemico-Biological Interactions , 175 :204 , 2008
Abstract : Sugimoto_2008_Chem.Biol.Interact_175_204
ESTHER : Sugimoto_2008_Chem.Biol.Interact_175_204
PubMedSearch : Sugimoto_2008_Chem.Biol.Interact_175_204
PubMedID: 18577377

Title : [New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis] -
Author(s) : Sugimoto H
Ref : Nihon Yakurigaku Zasshi , 131 :338 , 2008
PubMedID: 18480562

Title : Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe\/PS1dE9 mouse model of Alzheimer's disease - Goto_2008_Eur.J.Pharmacol_583_84
Author(s) : Goto Y , Niidome T , Hongo H , Akaike A , Kihara T , Sugimoto H
Ref : European Journal of Pharmacology , 583 :84 , 2008
Abstract : Goto_2008_Eur.J.Pharmacol_583_84
ESTHER : Goto_2008_Eur.J.Pharmacol_583_84
PubMedSearch : Goto_2008_Eur.J.Pharmacol_583_84
PubMedID: 18282567

Title : Donepezil potentiates nerve growth factor-induced neurite outgrowth in PC12 cells - Oda_2007_J.Pharmacol.Sci_104_349
Author(s) : Oda T , Kume T , Katsuki H , Niidome T , Sugimoto H , Akaike A
Ref : J Pharmacol Sci , 104 :349 , 2007
Abstract : Oda_2007_J.Pharmacol.Sci_104_349
ESTHER : Oda_2007_J.Pharmacol.Sci_104_349
PubMedSearch : Oda_2007_J.Pharmacol.Sci_104_349
PubMedID: 17675796

Title : Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity - Takada-Takatori_2006_Eur.J.Pharmacol_549_19
Author(s) : Takada-Takatori Y , Kume T , Sugimoto M , Katsuki H , Niidome T , Sugimoto H , Fujii T , Okabe S , Akaike A
Ref : European Journal of Pharmacology , 549 :19 , 2006
Abstract : Takada-Takatori_2006_Eur.J.Pharmacol_549_19
ESTHER : Takada-Takatori_2006_Eur.J.Pharmacol_549_19
PubMedSearch : Takada-Takatori_2006_Eur.J.Pharmacol_549_19
PubMedID: 16996497

Title : Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade - Takada-Takatori_2006_Neuropharmacol_51_474
Author(s) : Takada-Takatori Y , Kume T , Sugimoto M , Katsuki H , Sugimoto H , Akaike A
Ref : Neuropharmacology , 51 :474 , 2006
Abstract : Takada-Takatori_2006_Neuropharmacol_51_474
ESTHER : Takada-Takatori_2006_Neuropharmacol_51_474
PubMedSearch : Takada-Takatori_2006_Neuropharmacol_51_474
PubMedID: 16762377

Title : Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons - Kume_2005_Eur.J.Pharmacol_527_77
Author(s) : Kume T , Sugimoto M , Takada Y , Yamaguchi T , Yonezawa A , Katsuki H , Sugimoto H , Akaike A
Ref : European Journal of Pharmacology , 527 :77 , 2005
Abstract : Kume_2005_Eur.J.Pharmacol_527_77
ESTHER : Kume_2005_Eur.J.Pharmacol_527_77
PubMedSearch : Kume_2005_Eur.J.Pharmacol_527_77
PubMedID: 16313899

Title : [Scope and limitations of acetylcholinesterase inhibitors] - Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163
Author(s) : Sugimoto H
Ref : Nihon Yakurigaku Zasshi , 124 :163 , 2004
Abstract : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163
ESTHER : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163
PubMedSearch : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163
PubMedID: 15333989

Title : Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons - Takada_2003_J.Pharmacol.Exp.Ther_306_772
Author(s) : Takada Y , Yonezawa A , Kume T , Katsuki H , Kaneko S , Sugimoto H , Akaike A
Ref : Journal of Pharmacology & Experimental Therapeutics , 306 :772 , 2003
Abstract : Takada_2003_J.Pharmacol.Exp.Ther_306_772
ESTHER : Takada_2003_J.Pharmacol.Exp.Ther_306_772
PubMedSearch : Takada_2003_J.Pharmacol.Exp.Ther_306_772
PubMedID: 12734391

Title : Research and development of donepezil hydrochloride, a new type of acetylcholinesterase inhibitor - Sugimoto_2002_Jpn.J.Pharmacol_89_7
Author(s) : Sugimoto H , Ogura H , Arai Y , Limura Y , Yamanishi Y
Ref : Japanese Journal of Pharmacology , 89 :7 , 2002
Abstract : Sugimoto_2002_Jpn.J.Pharmacol_89_7
ESTHER : Sugimoto_2002_Jpn.J.Pharmacol_89_7
PubMedSearch : Sugimoto_2002_Jpn.J.Pharmacol_89_7
PubMedID: 12083745

Title : Donepezil hydrochloride: a treatment drug for Alzheimer's disease - Sugimoto_2001_Chem.Rec_1_63
Author(s) : Sugimoto H
Ref : Chem Rec , 1 :63 , 2001
Abstract : Sugimoto_2001_Chem.Rec_1_63
ESTHER : Sugimoto_2001_Chem.Rec_1_63
PubMedSearch : Sugimoto_2001_Chem.Rec_1_63
PubMedID: 11893059

Title : Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors - Sugimoto_2000_Curr.Med.Chem_7_303
Author(s) : Sugimoto H , Iimura Y , Kawakami Y , Yamanishi Y
Ref : Curr Med Chem , 7 :303 , 2000
Abstract : Sugimoto_2000_Curr.Med.Chem_7_303
ESTHER : Sugimoto_2000_Curr.Med.Chem_7_303
PubMedSearch : Sugimoto_2000_Curr.Med.Chem_7_303
PubMedID: 10637367

Title : Synthesis and biological evaluation of 1-(4-[18F]fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for in vivo studies of acetylcholinesterase - Lee_2000_Nucl.Med.Biol_27_741
Author(s) : Lee SY , Choe YS , Sugimoto H , Kim SE , Hwang SH , Lee K , Choi Y , Lee J , Kim B
Ref : Nucl Med Biol , 27 :741 , 2000
Abstract : Lee_2000_Nucl.Med.Biol_27_741
ESTHER : Lee_2000_Nucl.Med.Biol_27_741
PubMedSearch : Lee_2000_Nucl.Med.Biol_27_741
PubMedID: 11150705

Title : [Discovery and development of donepezil hydrochloride for the treatment of Alzheimer's disease] - Sugimoto_1999_Yakugaku.Zasshi_119_101
Author(s) : Sugimoto H , Yamanishi Y , Ogura H , Iimura Y , Yamatsu K
Ref : Yakugaku Zasshi , 119 :101 , 1999
Abstract : Sugimoto_1999_Yakugaku.Zasshi_119_101
ESTHER : Sugimoto_1999_Yakugaku.Zasshi_119_101
PubMedSearch : Sugimoto_1999_Yakugaku.Zasshi_119_101
PubMedID: 10067428

Title : Sequence, expression in Escherichia coli, and characterization of lysophospholipase II - Toyoda_1999_Biochim.Biophys.Acta_1437_182
Author(s) : Toyoda T , Sugimoto H , Yamashita S
Ref : Biochimica & Biophysica Acta , 1437 :182 , 1999
Abstract : Toyoda_1999_Biochim.Biophys.Acta_1437_182
ESTHER : Toyoda_1999_Biochim.Biophys.Acta_1437_182
PubMedSearch : Toyoda_1999_Biochim.Biophys.Acta_1437_182
PubMedID: 10064901
Gene_locus related to this paper: mouse-lypla2

Title : The dimer and trimer of 3-hydroxybutyrate oligomer as a precursor of ketone bodies for nutritional care - Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321
Author(s) : Tasaki O , Hiraide A , Shiozaki T , Yamamura H , Ninomiya N , Sugimoto H
Ref : JPEN J Parenter Enteral Nutr , 23 :321 , 1999
Abstract : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321
ESTHER : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321
PubMedSearch : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321
PubMedID: 10574479

Title : Purification, cDNA cloning, and regulation of lysophospholipase from rat liver - Sugimoto_1996_J.Biol.Chem_271_7705
Author(s) : Sugimoto H , Hayashi H , Yamashita S
Ref : Journal of Biological Chemistry , 271 :7705 , 1996
Abstract : Sugimoto_1996_J.Biol.Chem_271_7705
ESTHER : Sugimoto_1996_J.Biol.Chem_271_7705
PubMedSearch : Sugimoto_1996_J.Biol.Chem_271_7705
PubMedID: 8631810
Gene_locus related to this paper: ratno-lypla1a

Title : The rationale for E2020 as a potent acetylcholinesterase inhibitor - Kawakami_1996_Bioorg.Med.Chem_4_1429
Author(s) : Kawakami Y , Inoue A , Kawai T , Wakita M , Sugimoto H , Hopfinger AJ
Ref : Bioorganic & Medicinal Chemistry , 4 :1429 , 1996
Abstract : Kawakami_1996_Bioorg.Med.Chem_4_1429
ESTHER : Kawakami_1996_Bioorg.Med.Chem_4_1429
PubMedSearch : Kawakami_1996_Bioorg.Med.Chem_4_1429
PubMedID: 8894101

Title : The simulated binding of (+\/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]m eth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses - Inoue_1996_J.Med.Chem_39_4460
Author(s) : Inoue A , Kawai T , Wakita M , Iimura Y , Sugimoto H , Kawakami Y
Ref : Journal of Medicinal Chemistry , 39 :4460 , 1996
Abstract : Inoue_1996_J.Med.Chem_39_4460
ESTHER : Inoue_1996_J.Med.Chem_39_4460
PubMedSearch : Inoue_1996_J.Med.Chem_39_4460
PubMedID: 8893840

Title : Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2- yl)methyl]piperidine hydrochloride and related compounds - Sugimoto_1995_J.Med.Chem_38_4821
Author(s) : Sugimoto H , Iimura Y , Yamanishi Y , Yamatsu K
Ref : Journal of Medicinal Chemistry , 38 :4821 , 1995
Abstract : Sugimoto_1995_J.Med.Chem_38_4821
ESTHER : Sugimoto_1995_J.Med.Chem_38_4821
PubMedSearch : Sugimoto_1995_J.Med.Chem_38_4821
PubMedID: 7490731

Title : Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-(2-phthalimidoethyl)piperidine and related derivatives - Sugimoto_1992_J.Med.Chem_35_4542
Author(s) : Sugimoto H , Tsuchiya Y , Sugumi H , Higurashi K , Karibe N , Iimura Y , Sasaki A , Araki S , Yamanishi Y , Yamatsu K
Ref : Journal of Medicinal Chemistry , 35 :4542 , 1992
Abstract : Sugimoto_1992_J.Med.Chem_35_4542
ESTHER : Sugimoto_1992_J.Med.Chem_35_4542
PubMedSearch : Sugimoto_1992_J.Med.Chem_35_4542
PubMedID: 1469686

Title : Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives - Sugimoto_1990_J.Med.Chem_33_1880
Author(s) : Sugimoto H , Tsuchiya Y , Sugumi H , Higurashi K , Karibe N , Iimura Y , Sasaki A , Kawakami Y , Nakamura T , Araki S , Yamanishi Y , Yamatsu K
Ref : Journal of Medicinal Chemistry , 33 :1880 , 1990
Abstract : Sugimoto_1990_J.Med.Chem_33_1880
ESTHER : Sugimoto_1990_J.Med.Chem_33_1880
PubMedSearch : Sugimoto_1990_J.Med.Chem_33_1880
PubMedID: 2362265